• Title/Summary/Keyword: potential gradient

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Multi-classification of Osteoporosis Grading Stages Using Abdominal Computed Tomography with Clinical Variables : Application of Deep Learning with a Convolutional Neural Network (멀티 모달리티 데이터 활용을 통한 골다공증 단계 다중 분류 시스템 개발: 합성곱 신경망 기반의 딥러닝 적용)

  • Tae Jun Ha;Hee Sang Kim;Seong Uk Kang;DooHee Lee;Woo Jin Kim;Ki Won Moon;Hyun-Soo Choi;Jeong Hyun Kim;Yoon Kim;So Hyeon Bak;Sang Won Park
    • Journal of the Korean Society of Radiology
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    • v.18 no.3
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    • pp.187-201
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    • 2024
  • Osteoporosis is a major health issue globally, often remaining undetected until a fracture occurs. To facilitate early detection, deep learning (DL) models were developed to classify osteoporosis using abdominal computed tomography (CT) scans. This study was conducted using retrospectively collected data from 3,012 contrast-enhanced abdominal CT scans. The DL models developed in this study were constructed for using image data, demographic/clinical information, and multi-modality data, respectively. Patients were categorized into the normal, osteopenia, and osteoporosis groups based on their T-scores, obtained from dual-energy X-ray absorptiometry, into normal, osteopenia, and osteoporosis groups. The models showed high accuracy and effectiveness, with the combined data model performing the best, achieving an area under the receiver operating characteristic curve of 0.94 and an accuracy of 0.80. The image-based model also performed well, while the demographic data model had lower accuracy and effectiveness. In addition, the DL model was interpreted by gradient-weighted class activation mapping (Grad-CAM) to highlight clinically relevant features in the images, revealing the femoral neck as a common site for fractures. The study shows that DL can accurately identify osteoporosis stages from clinical data, indicating the potential of abdominal CT scans in early osteoporosis detection and reducing fracture risks with prompt treatment.

Characterization of a heat-resistant antimicrobial peptide secreted by Bacillus subtilis A405 (Bacillus subtilis A405 균주가 생성하는 내열성 항균 peptide의 특성 검정)

  • Koo, Bon-Sung;Lee, Seung-Bum;Yoon, Sang-Hong;Song, Gae-Kyung;Chung, Dae-Sung;Byun, Myung-Ok;Ryu, Jin-Chang
    • The Korean Journal of Pesticide Science
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    • v.2 no.3
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    • pp.28-35
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    • 1998
  • An antimicrobial peptide producing bacterium, Bacillus subtilis A405, was screened and identified among 700 of antagonistic bacteria. The heat-resistant antimicrobial peptide, AMP-405, was purified from the broth culture of B. subtilis A405 through $20{\sim}40%$ ammonium sulfate precipitation and ultrafiltration. The AMP-405 exhibited strong antimicrobial activities against Botrytis cinerea, Cercospora sp., Fusarium oxysporum, Penicillium digitatum, Celletotrichum gloeosporioides, Rhizoctonia solani, Pythium ultimum, Pyricularia oryzae, Escherichia coli, Pseudomonas spp. and Candida albicans. The molecular weight of the peptide was about 3.0 kDa determined by SDS-PAGE, Native-PAGE and Tris-Tricine gradient electrophoresis, and composed of 9 kinds of amino acid such as aspartic acid, glycine, serine, glutamine, valine, leucine, isoleucine, proline, tyrocine. To determine the efficiency of AMP-405 as a potential maintenance of fruits freshness, cherry tomato was srored at $25^{\circ}C$ for 2 weeks after treatment with $50{\mu}g/ml$ of AMP-405 and $10^{5}$ spores/ml of Botrytis cinerea simultaneously. Treatment with AMP-405 resulted in significantly less infection by Botrytis cinerea, than the treatment with tap water as a control.

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An Experimental Study on Ground Resistivity and Grounding Resistance of Water Environment (수상환경의 대지저항률 및 접지저항 측정의 실험적 연구)

  • Choi, Young-Kwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.4
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    • pp.2343-2348
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    • 2014
  • Main ground net of power plant is formed to protect human body from increase in potential gradient caused by grounding current during ground fault. Calculations during ground design are generally performed according to IEEE Std-80-2000 (Kepco Design Standard 2602). However, it is difficult to apply this Standard to water environment, and a grounding technology is required to secure grounding resistance of floating photovoltaic system. Therefore the aim of this paper is to investigate and analyze ground resistivity on the water surface and underwater of reservoir using Wenner 4-pin method, a general method of measuring ground resistivity. Also, grounding resistance of floating photovoltaic systems currently in operation was measured and analyzed using the voltage drop method suggested in the international standard (IEEE Std-81) to propose a grounding method for stable grounding of floating photovoltaic system. The resistivity at 1m below the surface of water ($126.3969[{\Omega}{\cdot}m]$) is mostly higher than resistivity at the river bed ($97.5713[{\Omega}{\cdot}m]$). Also the proposed grounding anchor method was determined as the most effective method of securing stable grounding resistance in floating photovoltaic systems and is expected to be utilized as a ground method for future floating photovoltaic generation systems.

Effect of Lactobacillus mucosae on In vitro Rumen Fermentation Characteristics of Dried Brewers Grain, Methane Production and Bacterial Diversity

  • Soriano, Alvin P.;Mamuad, Lovelia L.;Kim, Seon-Ho;Choi, Yeon Jae;Jeong, Chang Dae;Bae, Gui Seck;Chang, Moon Baek;Lee, Sang Suk
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.11
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    • pp.1562-1570
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    • 2014
  • The effects of Lactobacillus mucosae (L. mucosae), a potential direct fed microbial previously isolated from the rumen of Korean native goat, on the rumen fermentation profile of brewers grain were evaluated. Fermentation was conducted in serum bottles each containing 1% dry matter (DM) of the test substrate and either no L. mucosae (control), 1% 24 h broth culture of L. mucosae (T1), or 1% inoculation with the cell-free culture supernatant (T2). Each serum bottle was filled anaerobically with 100 mL of buffered rumen fluid and sealed prior to incubation for 0, 6, 12, 24, and 48 h from which fermentation parameters were monitored and the microbial diversity was evaluated. The results revealed that T1 had higher total gas production (65.00 mL) than the control (61.33 mL) and T2 (62.00 mL) (p<0.05) at 48 h. Consequently, T1 had significantly lower pH values (p<0.05) than the other groups at 48 h. Ammonia nitrogen ($NH_3$-N), individual and total volatile fatty acids (VFA) concentration and acetate:propionate ratio were higher in T1 and T2 than the control, but T1 and T2 were comparable for these parameters. Total methane ($CH_4$) production and carbon dioxide ($CO_2$) were highest in T1. The percent DM and organic matter digestibilities were comparable between all groups at all times of incubation. The total bacterial population was significantly higher in T1 (p<0.05) at 24 h, but then decreased to levels comparable to the control and T2 at 48 h. The denaturing gradient gel electrophoresis profile of the total bacterial 16s rRNA showed higher similarity between T1 and T2 at 24 h and between the control and T1 at 48 h. Overall, these results suggest that addition of L. mucosae and cell-free supernatant during the in vitro fermentation of dried brewers grain increases the VFA production, but has no effect on digestibility. The addition of L. mucosae can also increase the total bacterial population, but has no significant effect on the total microbial diversity. However, inoculation of the bacterium may increase $CH_4$ and $CO_2$ in vitro.

Convergence Analysis of the Least Mean Fourth Adaptive Algorithm (최소평균사승 적응알고리즘의 수렴특성 분석)

  • Cho, Sung-Ho;Kim, Hyung-Jung;Lee, Jong-Won
    • The Journal of the Acoustical Society of Korea
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    • v.14 no.1E
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    • pp.56-64
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    • 1995
  • The least mean fourth (LMF) adaptive algorithm is a stochastic gradient method that minimizes the error in the mean fourth sense. Despite its potential advantages, the algorithm is much less popular than the conventional least mean square (LMS) algorithm in practice. This seems partly because the analysis of the LMF algorithm is much more difficult than that of the LMS algorithm, and thus not much still has been known about the algorithm. In this paper, we explore the statistical convergence behavior of the LMF algorithm when the input to the adaptive filter is zero-mean, wide-sense stationary, and Gaussian. Under a system idenrification mode, a set of nonlinear evolution equations that characterizes the mean and mean-squared behavior of the algorithm is derived. A condition for the conbergence is then found, and it turns out that the conbergence of the LMF algorithm strongly depends on the choice of initial conditions. Performances of the LMF algorithm are compared with those of the LMS algorithm. It is observed that the mean convergence of the LMF algorithm is much faster than that of the LMS algorithm when the two algorithms are designed to achieve the same steady-state mean-squared estimation error.

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Hot-wall epitaxial growth and characterization of $Cd_{1-x}Mn_xTe$ films (Hot-wall epitaxy 법에 의한 $Cd_{1-x}Mn_xTe$ 박막의 성장과 특성)

  • 황영훈;엄영호
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.9 no.1
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    • pp.126-131
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    • 1999
  • $Cd_{1-x}Mn_xTe$ thin films were grown on GaTs (100) substrates by hot-wall epitaxy method. From the XRD measurements, it was found that CdTe/GaAs (100)film was grown as a single crystal with the same growth plane of (100) and $Cd_{1-x}Mn_xTe$film as a poly crystal as Mn content was increased, and the lattice constant was decressed with the similar gradient of bulk crystal as x was increased. From the PL measurements, $L_1$line due to the exciton trapped on an acceptor and $L_2$line due to an exciton trapped on a shallow potential fluctuation were observed, and $L_1$line was observed only in $Cd_{0.91}Mn_{0.09}$te but it was disappeared probably due to a stronger lacalization of excitons with increasing alloy fluctuation.$L_2$line was dominant in case of $x{\ge}0.2$and for higher Mn contents the broad transition about 2.0eV associated to the 3d levels of the $Mn^{2+}$ ion dominated the PL spectrum, and the $L_2$ transition become weaker and weaker. For$x{\ge}0.4$, the transition line about 2.0eV due to $Mn^{2+}$ion showed no shift.

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The quality investigation of 6H-SiC crystals grown by conventional PVT method with various SiC powders

  • Yeo, Im-Gyu;Lee, Won-Jae;Shin, Byoung-Chul
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.06a
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    • pp.113-114
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    • 2009
  • Silicon carbide is one of the most attractive and promising wide band-gap semiconductor material with excellent physical properties and huge potential for electronic applications. Up to now, the most successful method for growth of large SiC crystals with high quality is the physical vapor transport (PVT) method [1, 2]. Since further reduction of defect densities in larger crystal are needed for the true implementation of SiC devices, many researchers are focusing to improve the quality of SiC single crystal through the process modifications for SiC bulk growth or new material implementations [3, 4]. It is well known that for getting high quality SiC crystal, source materials with high purity must be used in PVT method. Among various source materials in PVT method, a SiC powder is considered to take an important role because it would influence on crystal quality of SiC crystal as well as optimum temperature of single crystal growth, the growth rate and doping characteristics. In reality, the effect of powder on SiC crystal could definitely exhibit the complicated correlation. Therefore, the present research was focused to investigate the quality difference of SiC crystal grown by conventional PVT method with using various SiC powders. As shown in Fig. 1, we used three SiC powders with different particles size. The 6H-SiC crystals were grown by conventional PVT process and the SiC seeds and the high purity SiC source materials are placed on opposite side in a sealed graphite crucible which is surrounded by graphite insulation[5, 6]. The bulk SiC crystal was grown at $2300^{\circ}C$ of the growth temperature and 50mbar of an argon pressure. The axial thermal gradient across the SiC crystal during the growth is estimated in the range of $15\sim20^{\circ}C/cm$. The chemical etch in molten KOH maintained at $450^{\circ}C$ for 10 min was used for defect observation with a polarizing microscope in Nomarski mode. Electrical properties of bulk SiC materials were measured by Hall effect using van der Pauw geometry and a UV/VIS spectrophotometer. Fig. 2 shows optical photographs of SiC crystal ingot grown by PVT method and Table 1 shows electrical properties of SiC crystals. The electrical properties as well as crystal quality of SiC crystals were systematically investigated.

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Honeycomb-type Single Chamber SOFC Running on Methane-Air Mixture (Methane-Air 혼합 Gas에서 구동하는 하니컴 형태의 SC-SOFC)

  • Park Byung-Tak;Yoon Sung Pil;Kim Hyun Jae;Nam Suk Woo;Han Jonghee;Lim Tae-Hoon;Hong Seong-Ahn;Lee Dokyol
    • 한국신재생에너지학회:학술대회논문집
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    • 2005.06a
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    • pp.306-309
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    • 2005
  • One of the most critical issues in sol id oxide fuel cell (SOFC)running on hydrocarbon fuels is the risk of carbon formation from the fuel gas. The simple method to reduce the risk of carbon formation from the reactions is to add steam to the fuel stream, leading to the carbon gasification react ion. However, the addition of steam to fuel is not appropriate for the auxiliary power unit (APU) and potable power generation (PPG) systems due to an increase of complexity and bulkiness. In this regard, many researchers have focused on so-called 'direct methane' operation of SOFC, which works with dry methane without coking. However, coking can be suppressed only by the operation with a high current density, which may be a drawback especially for the APU and PPG systems. The single chamber fuel cell (SC-SOFC) is a novel simplification of the conventional SOFC into which a premixed fuel/air mixture is introduced. It relies on the selectivity of the anode and cathode catalysts to generate a chemical potential gradient across the cell. Moreover it allows compact and seal-free stack design. In this study, we fabricated honeycomb type mixed-gas fuel cell (MGFC) which has advantages of stacking to the axial direction and increasing volume power density. Honeycomb-structured SOFC with four channels was prepared by dry pressing method. Two alternative channels were coated with electrolyte and cathode slurry in order to make cathodic reaction sites. We will discuss that the anode supported honeycomb type cell running on mixed gas condition.

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Role of Electrode Reaction of Electrolyte in Electrokinetic-Fenton Process for Phenanthrene Removal (동전기-펜턴 공정에서 전해질의 전극반응이 처리효율에 미치는 영향)

  • Park Ji-Yeon;Kim Sang-Joon;Lee You-Jin;Yang Ji-Won
    • Journal of Soil and Groundwater Environment
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    • v.11 no.1
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    • pp.7-13
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    • 2006
  • The effects of electrolytes were investigated on the removal efficiency when several different electrolytes were used to change the electrode reaction in an electrokinetic (EK)-Fenton process to remediate phenanthrene-contaminated soil. Electrical potential gradient decreased initially due to the ion entrance into soil and then increased due to the ion extraction from soil under the electric field. Accumulated electroosmotic flow was $NaCl>KH_2PO_4>MgSO_4$ at the same concentration because the ionic strength of $MgSO_4$ was the highest and $Mg(OH)_2$ formed near the cathode reservoir plugged up soil pore to inhibit water flow. When hydrogen peroxide was contained in electrolyte solution, removal efficiency increased by Fenton reaction. When NaCl was used as an electrolyte compound, chlorine ($Cl_2$) was generated at the anode and dissolved to form hypochlorous acid (HClO), which increased phenanthrene removal. Therefore, the electrode reaction of electrolyte in the anode reservoir as well as its transport into soil should be considered to improve removal efficiency of EK-Fenton process.

Effects of Air Current Speed on the Microclimates of the Plug Stand under Artificial Light (기류속도가 인공광하에서 공정육묘 개체군의 미기상에 미치는 영향)

  • 김용현;고재풍수
    • Journal of Bio-Environment Control
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    • v.5 no.2
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    • pp.160-166
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    • 1996
  • Objective of this study was to investigate the effects of all current speed on the microclimates above and inside the plug stand under artificial light. Maximum air temperature appeared near the top of the plug stand. Difference in air temperature inside the plug stand increased with the decreasing air current speed. Difference in relative humidity(DRH) to the relative humidity at the Inlet of the main air flow conditioner Inside and above the plug stand decreased with the increasing air current speed. Relative humidity inside the plug stand was 10-15% higher than that above the plug stand. DRH inside a stand of plug at air current speed of 0.3m s$^{-1}$ was about two times as many as that at air current speed of 0.9 m s$^{-1}$ . DRH inside the plug stand was 2.8-6.5% higher at LAI of 2.6 than that at LAI of 0.5. Gradient for the vapour pressure deficit was distinctly appeared at the low air current speed. Direction of vapour pressure flux is from the medium surface upwards. Difference in vapour pressure(DVPD) to the vapour pressure deficit at the inlet of the main air flow conditioner inside and above the plug stand decreased with the increasing height above the medium surface. DVPD inside the plug stand was 0.3-0.4㎪ higher at air current speed of 0.9m s$^{-1}$ than that at air current speed of 0.3m s$^{-1}$ . Results for the effects of air current speed on the relative humidity and vapour pressure deficit indicated that the microclimates above and inside the plug stand at the rear region in plug trays were slightly unfavorable compared to those at middle region.

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