• Asian Pacific Journal of Cancer Prevention
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• v.13 no.1
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• pp.361-365
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• 2012

Aims: To investigate the relationship between the expression of ${\beta}$-tubulin III and survivin in advanced breast cancers and chemotherapeutic effects of docetaxel. Methods: Clinical pathological data of 74 patients with advanced breast cancer were retrospectively analyzed after docetaxel chemotherapy. Expression of ${\beta}$-tubulin III and survivin was assessed by immunohistochemistry and analyzed with reference to therapeutical and adverse effects of docetaxel. Results: The positive expression rate of ${\beta}$-tubulin III was 38.1% (32/84), while that of survivin was 76.2% (64/84). The effective rate (complete response + partial response) was 52.4%. That for patients with the positive expression of ${\beta}$-tubulin III or/and survivin was significantly lower than for those with negative expression (P<0.05). There were significant differences in the non-progression of median diseases, 1-year and 2-year survival rates of between the patients with positive and negative expression (P<0.05). The main side effects were myelosuppression, alimentary canal response and alopecie, no differences being observed between groups. Conclusions: The combined detection of ${\beta}$-tubulin III and survivin is a predictive index for chemotherapy effects of docetaxel in metastatic breast cancer.

• The Korean Journal of Pain
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• v.14 no.2
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• pp.199-206
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• 2001

Background: The lumbar sympathetic ganglia are variable in both position and numbers. The aim of this study was to detect the appropriate lumbar vertebral level where the lumbar sympathetic ganglia primarily aggregate. Methods: Forty patients comprising of hyperhidrosis (26 cases), complex regional pain syndrome (10 cases), peripheral artery occlusion disease (3 cases) and postherpetic neuralgia (1 case) underwent lumbar sympathetic block. We randomly selected one of two (L2 or L3) levels and the L4 level. The position of the needle tip and distribution of dye was verified by injection of a mixture of radio-opaque dye (1.5 ml) and 4% lidocaine (1.5 ml) and subsequently confirmed by L-spine anteroposterior and a lateral view X-ray. We considered the response positive when the skin temperature increased more than $1^{\circ}C$ in 5 min. Results: In general, the positive response ratio was greater when the needle tip located at the L2 or L4 level vice L3 and when the drug was distributed on the lower half of the L4 body and in the L4/5 intervertebral disc space. In a right side block, the positive response ratio was greater when the drug was distributed on the lower half of the L4 body and in the L4/5 intervertebral disc space, although in a left side block there was no significant difference seen between the levels. The complications of the neurolytic block were alcohol neuritis (7.5%) and hypoesthesia (5%) on the L1 or L2 dermatome. Conclusions: The best effect with least chance of complication may be induced by spreading the drug on the lower half of the L4 body and/or into the L4/5 intervertebral disc space by placing the needle tip on the L4 body.

• Journal of Distribution Research
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• v.6 no.2
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• pp.65-89
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• 2002

Compromise is a conflict-resolution mechanism whereby both parties mutually make concessions and reach an agreement somewhere between their initial positions. In the process of a compromise, both parties may engage in three kinds of behaviors with respect to concessions. First, a party makes a concession in response to another's concession (a positive matching behavior). Second, a party makes a demand in response to another's demand (a negative matching behavior). Third, a party makes a concession/demand in response to another's demand/concession (a mismatching behavior). A situation is considered where a manufacturer intends to resolve a conflict with a distributor using a compromise. In this situation, a conceptual framework is addressed. This framework presents a set of variables affecting the likelihood that given a manufacturer's concession, the distributor engages in a positive matching behavior, Then, the framework explains how this positive matching behavior affects the distributor's commitment to the relationship with the manufacturer. Seventeen propositions are derived from the conceptual framework. Discussions on conflict-resolution strategies are developed on the basis of this framework.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.116.1-116.1
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• 2012

When an interplanetary (IP) shock passes over the Earth's magnetosphere, the geosynchronous magnetic field strength near the noon is always enhanced, while the geosynchronous magnetic field near the midnight decreases or increases. In order to understand what determines the positive or negative magnetic field response at nightside geosynchronous orbit to sudden increases in the solar wind dynamic pressure, we have examined 120 IP shock-associated sudden commencements (SC) using magnetic field data from the GOES spacecraft near the midnight (MLT = 2200~0200) and found the following magnetic field perturbation characteristics. (1) There is a strong seasonal dependence of geosynchronous magnetic field perturbations during the passage of IP shocks. That is, the SC-associated geosynchronous magnetic field near the midnight increases (a positive response) in summer and decreases (a negative response) in winter. (2) These field perturbations are dominated by the radial magnetic field component rather than the north-south magnetic field component at nightside geosynchronous orbit. (3) The magnetic elevation angles corresponding to positive and negative responses decrease and increase, respectively. These field perturbation properties can be explained by the location of the cross-tail current enhancement during SC interval with respect to geosynchronous spacecraft position.

• Asia Marketing Journal
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• v.9 no.3
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• pp.75-115
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• 2007

This study investigated the effect of service provider's recovery effort and pre-failure customer-employee rapport on post-recovery consumer response such as satisfaction, purchase intention, and positive Word-of-Mouth communication. First, this study explored the interaction effect of recovery effort and customer-employee rapport on post-recovery consumer response. The result shows when the level of pre-failure customer-employee rapport is high, customer's positive responses decreased slightly even though they perceived low recovery effort. However, when the level of pre-failure customer-employee rapport is low, customer's responses were decreased considerably in case of low recovery effort. Second, this study examined 'service recovery paradox' which is post-recovery consumer's satisfaction is greater than the case of no service failure. The result shows recovery paradox was not supported in all samples regardless of the level of recovery effort and customer-employee rapport. Synthetically, customer-employee rapport took a buffering role in customer response after service failure although it's not the same as error-free state.

• The Pure and Applied Mathematics
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• v.17 no.3
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• pp.211-229
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• 2010

Various types of predator-prey systems are studied in terms of the stabilities of their steady-states. Necessary conditions for the existences of non-negative constant steady-states for those systems are obtained. The linearized stabilities of the non-negative constant steady-states for the predator-prey system with monotone response functions are analyzed. The predator-prey system with non-monotone response functions are also investigated for the linearized stabilities of the positive constant steady-states.

• Journal of the Korea Safety Management & Science
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• v.10 no.2
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• pp.25-31
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• 2008

The purpose of this paper is to review the relationship between job characteristics and job stress responses(physiological response, psychological response, behavioral response), and the moderating effect of social support. Based on the responses from 187 employees in small & medium manufacturing industry, hierarchical regressional analysis showed that job characteristics factors have partly negative relationships with job stress response. However, job variety has positive relationship. Social support has partly moderating effect on the relationship between job characteristics and job stress.

• Communications for Statistical Applications and Methods
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• v.24 no.2
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• pp.163-172
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• 2017

Economic sentiment is typically measured using ordinary response options. The University of Michigan and the United States Conference Board are two widely used major indexes that have separately established independent consumer sentiment indexes based on three-level ordinary response options: positive, neutral, and negative. Notwithstanding, limited attention has been paid to the structural differences in their built-in formulas, which are referred to the disparate micro scoring schemes applied to an individual question. This paper examines the structural difference of the two indexes and then addresses situations where one is more reliable than the other. Real data from business tendency surveys of the Organization for Economic Cooperation and Development are used to illustrate our points empirically. As a conclusion, it is stressed that the two indexes should be handled with care when applied to economic sentiment comparison studies.

• Journal of the Korean housing association
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• v.7 no.1
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• pp.105-116
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• 1996

The purpose of this study is to improve the quality of the light environment of classroom. To attain this purpose, this study estimated the physical factor and evaluation of the subjective response of classroon located in south and north in the summer and the winter. The results are as followed. 1. The evaluation of the illumination, uniformity factor, daylight factor as physical factor of light environment is good as classroom, but the classroom in south is better that that in north, the light environment in summer is better than winter. 2. The subjective response to light environment of classroom is positive on both seasons at all calssroom. Comparing summer with winter, I found that the difference of subjective response between both classrooms on summer is attentive. 3. The realtion between subjective response and physical factor of light environment in classroom is attentive on the light sense, content sense, uniformity.

• Proceedings of the Acoustical Society of Korea Conference
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• 1994.06a
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• pp.686-691
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• 1994

For evaluating the response fluctuation of the actual environmental acoustic system excited by arbitrary random inputs, it is important to predict a whole probability distribution form closely connected with evaluation indexes Lx, Leq and so on. In this paper, a new type evaluation method is proposed by introducing three functional models matched to the prediction of the response probability distribution from a problem-oriented viewpoint. Because of the positive variable of the sound intensity, the response probability density function can be reasonably expressed theoretically by a statistical Laguerre expansion series form. The relationship between input and output is described by the regression relationship between the distribution parameters(containing expansion coefficients of this expression) and the stochastic input. These regression functions are expressed in terms of the orthogonal series expansion and their parameters are determined based on the least-squares error criterion and the measure of statistical independency.