• 대한예방한의학회지
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• 제13권2호
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• pp.27-38
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• 2009

Objective : This study was to examine a relationship among subjective psychological stress, physical stress response and oxidative stress. Methods : The subjects were consisted of 87 healthy volunteers. To assess subjective psychological stress, SRI(stress response inventory) was completed. To assess psychological and physical stress response, HRV(Heart Rate Variability) were tested. To assess oxidative stress, d-roms(Derivatives of reactive oxygen metabolites test) test was conducted. Subjects were divided into 3 groups depending on SRI(Stress Response Inventory) score, low stress response(LSR: lower than 30 percentile), Medium(MSR: 30-70 percentile) and high stress response(HSR: higher than 70 percentile). The Relationship between Stress Response and Oxidative Stress was estimated by correlation and One-way ANOVA analysis. Results : There were no significant differences of demographic data among 3 groups. There was a significant difference of oxidative stress among 3 groups. Conclusion : Our results suggest that there is a weak positive correlation between subjective psychological stress and oxidative stress. There is a significant difference of oxidative stress between HSR group and LSR group.

• 전력전자학회논문지
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• 제13권2호
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• pp.145-151
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• 2008

본 논문에서는 계통 전압이 불평형인 경우에 정확한 위상각을 검출할 수 있는 정상분 전압 관측기를 이용한 PLL(Phase Locked Loop) 방법을 제안한다. 제안된 PLL 방법은 기존의 전역 통과 필터(APF, All Pass Filter)를 이용하여 불평형 전원전압으로부터 정상분 전압을 구하는 것과는 달리 전차원 상태관측기를 사용함으로써 불평형사고 발생 시 추정위상각의 과도상태 응답특성을 개선하였다. 기존의 정상분 전압 추출 PLL 방법과 본 논문에서 제안된 PLL 방법의 성능을 비교하기 위해, 전원단 전압에 불평형 사고 발생시 위상각을 검출하는 실험을 하였고, 이를 통해 기존의 전역 통과 필터를 이용한 정상분 전압 추출 PLL 방법보다 제안된 전차원 상태관측기를 이용한 정상분 전압 추출 PLL 방법의 과도상태 응답특성이 개선됨을 입증하였다.

• 전력전자학회논문지
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• 제20권1호
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• pp.19-30
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• 2015

A static synchronous compensator (STATCOM) applied to rapidly changing, highly unbalanced loads such as electric arc furnaces (EAFs), requires both positive-sequence and negative-sequence current control, which indicates fast response characteristics and can be controlled independently. Furthermore, a delta-connected STATCOM with cascaded H-bridge configuration accompanying multiple separate DC-sides, should have high performance zero-sequence current control to suppress a phase-to-phase imbalance in DC-side voltages when compensating for unbalanced load. In this paper, actual EAF data is analyzed to reflect on the design of current controllers and a pioneering zero-sequence current controller with a superb transient performance is devised, which generates an imaginary -axis component from the presumed response of forwarded reference. Via simulation and experiments, the performance of the positive, negative, and zero-sequence current control of a cascaded H-bridge STATCOM for EAF is verified.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 제39회 하계학술대회
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• pp.2100-2101
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• 2008

This paper is studied on a protective control system for electrical fire and electrical faults due to over current or electric short circuit faults by using electrical thermal characteristics of PTC (Positive Temperature Coefficient) thermistor and current response characteristics of high sensitive reed switch. The PTC thermistor has characteristic of positive resistivity temperature coefficient according to the temperature variation, which is construction of a regular square and cube demarcation with BaTiO3_Ceramics of positive temperature coefficient. Also PTC thermistor shows the phenomenon which is rapidly increased in the resistivity if the temperature is increased over Curie temperature point, and reed switch, which is used for electrical fault current sensing devices, have a excellent characteristic of response velocity in degree of ${\mu}s{\sim}ms$ that sensing magnetic flux in proportion to dimension of line current. This paper is proposed on a protective control system use PTC thermistor and reed switch for sensor which is protected from electrical fire due to overload faults or electric short circuit faults. Some experimental results of the proposed electric safety control device are confirmed to the validity of the analytical results.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 하계학술대회 논문집 Vol.9
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• pp.399-400
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• 2008

The light efficiency of fringe-field switching (FFS) mode when using a liquid crystal (LC) with positive dielectric anisotropy was found to be dependent on the magnitude of dielectric anisotropy, such that the lower dielectric anisotropy, the higher. We studied out not only light efficiency but also response time according to dependence on the magnitude of dielectric anisotropy. Rising and decay time became fast and slow respectively according to decreasing the magnitude of dielectric anisotropy. This paper investigates electro-optical characteristic of FFS mode using LC with a positive dielectric anisotropy dependent on the magnitude of dielectric anisotropy of the LC.

• 경영과정보연구
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• 제34권4호
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• pp.97-120
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• 2015

본 연구는 소비자 공감 반응에 대한 연구로 이론적 배경을 바탕으로 하여 실증분석을 통해 검증하였으며, 연구결과를 토대로 연구결과를 요약하면 다음과 같다. 소비자 공감 반응에 대한 관계를 살펴보기 위해 인지적 반응(매력성, 친숙성, 실제적 자아일치성, 이상적 자아일치성 그리고 동감)요인, 감정적 반응(공감, 몰입, 애착) 그리고 인지적 반응과 감정적 반응을 매개하는 동일시와 상호작용성의 역할 및 관계를 살펴보고자 하였다. 본 연구의 가설을 검증한 결과 2개의 가설(가설 1-1, 가설 3)을 제외하고 모든 가설이 채택되었다. 이에 대한 구체적인 결과는 다음과 같다. 첫째, 인물매력성, 실제적 자아일치성을 제외하고, 스토리 매력성, 인물친숙성, 스토리친숙성, 이상적 자아일치성은 동감에 정의 영향을 미치고 있음을 알 수 있다. 둘째, 인지적 반응과 감정적 반응을 매개하는 변수로 동일시, 그리고 상호작용성의 관계 및 역할을 살펴보면 다음과 같다. 동감반응과 공감반응의 매개 역할로 동일시와 상호작용성 모두 정의 영향을 미치고 있음을 알 수 있다. 셋째, 감정적 반응간의 관계를 살펴보면 다음과 같다. 먼저 공감과 몰입 그리고 애착은 모두 정의 영향을 미치고 있음을 알 수 있다.

• 한국산학기술학회논문지
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• 제14권10호
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• pp.5003-5011
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• 2013

본 논문은 정서-주의 태스크를 수행할 때의 신경학적, 행동학적 반응이 정서조절 능력을 반영할 수 있는지를 측정하였다. 이를 위해, 건강한 성인 남녀 19명을 대상으로 3일에 걸쳐 1일 1회씩 동일 시간대에 정서-주의 상호작용이 요구되는 실험을 수행하였다. 이 실험을 통해 정서를 유발하는 비디오를 보여주기 전과 후, 정서-주의 태스크를 수행할 때의 EEG와 반응시간이 측정되었다. ERP P100과 P300 성분 간의 밀접한 상관관계가 나타났으며, P100 진폭이 높을수록 P300 잠재기가 길게 나타났다. 또한 P300 잠재기가 길수록 반응시간이 길게 나타났다. 또한, 정서-주의 태스크를 수행할 때 ERP 성분과 반응시간에 개인별 차이가 존재하였다. 정서유발을 위해 사용된 비디오 자극의 유형에 관계없이 ERP 성분의 낮은 진폭과 빠른 잠재기를 나타낸 집단이 더 빠른 반응시간을 나타내었다. 이러한 반응특성은 목표인식에 대한 성급한 반응으로 해석될 수 있으며, 낮은 정서 조절력과 관련이 있다고 할 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권10호
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• pp.4117-4123
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• 2014

Background: To determine prognostic value of excision repair cross-complementation 1 (ERCC1) in patients with malignant pleural mesothelioma (MPM). Materials and Methods: The study included 60 patients with MPM who were diagnosed and treated in the Radiation Oncology Department of Kayseri Teaching Hospital and Medical Oncology Department of Erciyes University, Medicine School between 2005 and 2013. By using immunohistochemical methods, ERCC1 expression in biopsy specimens was evaluated. We retrospectively assessed whether there is a correlation between ERCC1 and response to anti-neoplastic therapy or survival. Results: There were 50 men and 10 women with median age of 62 years (range: 39-83). Histological type was epithelial mesothelioma in the majority of the cases (85%), most commonly presenting in stage four. Of the cases, 20 (33%) received radiotherapy, 60 (%100) received first-line chemotherapy and 15 (%25) received second-line chemotherapy. In the assessment after therapy, it was found that there was partial response in 12 cases (20%), stable disease in 19 cases (31.4%) and progression in 25 cases (41.7%). ERCC1 was positive in 43% of the cases. Mean OS was 11.7 months and mean DFS was 9.5 months in ERCC1-positive cases regardless of therapy, while they were 19.2 months and 17.1 months in ERCC1-negative cases, respectively. The difference was found to be significant (p<0.05). In univariate analysis, stage, comorbidity, response to treatment and ERCC1 expression were found to be significantly associated with OS (p=0.083; p=0.043; p=0.041; p=0.050). In multivariate analysis, response to treatment remained to be significant for OS (p=0.005). In univariate and multivariate analyses, response to treatment and ERCC1 were found to be significantly associated with DFS (p=0.049; p=0.041). Conclusions: ERCC1 was identified as poor prognostic factor in patients with MPM.

• Journal of Preventive Medicine and Public Health
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• 제38권2호
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• pp.170-174
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• 2005

Objectives: The aim of this study was to evaluate the response to a hepatitis B vaccination, and investigate the HBV DNA in subjects with isolated anti-HBc. Methods: 34 subjects with persistent isolated anti-HBc were included in the study. 32 subjects negative for HBsAg, anti-HBs and anti-HBc were included as a control group. They were all vaccinated with Hepaccine at 0, 1 and 2 months, and anti-HBs titers were measured 1 month after the 1st and 3rd vaccinations (1 and 3 months). The HBV-DNA was tested by polymerase chain reaction in subjects with isolated anti-HBc. Results: After the 1st & 3rd vaccinations, the anti-HBs titers$\geq$10mIU/ml were 70.6 & 70.6% in isolated anti-HBc group, and 34.4 & 81.2% in the control group, respectively. There were statistically significant differences after the 1st vaccination, but none after the 3rd, between the two groups. In the isolated anti-HBc and control groups, the primary, amnestic and no responses were 0 vs. 46.9%, 55.9 vs. 6.3% and 29.4 vs. 18.8%, respectively. The HBV DNA was not detected in all subjects with isolated anti-HBc. Conclusion: None of the subjects with isolated anti-HBc had a false positive result (primary response); therefore, they should be excluded from vaccination programs in Korea. To differentiate between immunity and occult infections, a single dose of vaccine, with a follow-up anti-HBs test, is preferable for subjects with isolated anti-HBc. An amnestic response indicates late immunity, and no response a suspect occult infection.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.2753-2758
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• 2013

Various studies examining the relationship between Ezrin overexpression and response to chemotherapy and clinical outcome in patients with osteosarcoma have yielded inconclusive results. We accordingly conducted a meta-analysis of 7 studies (n = 318 patients) that evaluated the correlation between Ezrin and histologic response to chemotherapy and clinical prognosis (death). Data were synthesized in receiver operating characteristic curves and with fixed-effects and random-effects likelihood ratios and risk ratios. Quantitative synthesis showed that Ezrin is not a prognostic factor for the response to chemotherapy. The positive likelihood ratio was 0.538 (95% confidence interval [95% CI], 0.296- 0.979; random-effects calculation), and the negative likelihood ratio was 2.151 (95% CI, 0.905- 5.114; random-effects calculations). There was some between-study heterogeneity, but no study showed strong discriminating ability. Conversely, Ezrin positive status tended to be associated with a lower 2-year survival (risk ratio, 2.45; 95% CI, 1.26-4.76; random-effects calculation) with some between-study heterogeneity that disappeared when only studies that employed immunohistochemistry were considered (risk ratio, 2.97; 95% CI, 2.01- 4.40; fixed-effects calculation). To conclude, Ezrin is not associated with the histologic response to chemotherapy in patients with osteosarcoma, whereas Ezrin positivity was associated with a lower 2-year survival rate regarding risk of death at 2 years. Expression change of Ezrin is an independent prognostic factor in patients with osteosarcoma.