• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3791-3794
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• 2012

CD44v, especially splice variants containing exon v6, has been shown to be related closely to development of different tumors. High levels of CD44v6/v7 have been reported to be associated with invasiveness and metastasis of many malignancies. The objective of this study was to detect expression of CD44v6-containing variants in patients with acute promyelocytic leukemia (APL) and evaluate the potential of CD44v6/v7 for risk stratification. Reverse transcription polymerase chain reaction (RT-PCR) followed by PCR product purification, ligation into T vectors and positive clone sequencing were used to detect CD44 v6-containing variant isoforms in 23 APL patients. Real-time quantitative PCR of the CD44v6/v7 gene was performed in patients with APL and in NB4 cells that were treated with all-trans retinoic acid (ATRA) or arsenic trioxide ($As_2O_3$). Sequencing results identified four isoforms (CD44v6/v7, CD44v6/v8/v10, CD44v6/v8/v9/v10, and CD44v6/v7/v8/v9/v10) in bone marrow mononuclear cells of 23 patients with APL. The level of CD44v6/v7 in high-risk cases was significantly higher than those with low-risk. Higher levels of CD44v6/v7 were found in three patients with central nervous system relapse than in other patients inthe same risk group. Furthermore, in contrast to ATRA, only $As_2O_3$ could significantly down-regulate CD44v6/v7 expression in NB4 cells. Our data suggest that CD44v6/v7 expression may be a prognostic indicator for APL.

• The Journal of Society for e-Business Studies
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• v.24 no.4
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• pp.119-133
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• 2019

Recently, the importance prediction of photovoltaic power (PV) is considered as an essential function for scheduling adjustments, deciding on storage size, and overall planning for stable operation of PV facility systems. In particular, since most of PV power is generated in peak time, PV power prediction in a peak time is required for the PV system operators that enable to maximize revenue and sustainable electricity quantity. Moreover, Prediction of the PV power output in peak time without meteorological information such as solar radiation, cloudiness, the temperature is considered a challenging problem because it has limitations that the PV power was predicted by using predicted uncertain meteorological information in a wide range of areas in previous studies. Therefore, this paper proposes the LSTM (Long-Short Term Memory) based the PV power prediction model only using the meteorological, seasonal, and the before the obtained PV power before peak time. In this paper, the experiment results based on the proposed model using the real-world data shows the superior performance, which showed a positive impact on improving the PV power in a peak time forecast performance targeted in this study.

• The Journal of the Convergence on Culture Technology
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• v.6 no.3
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• pp.253-260
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• 2020

The purpose of this study is to verify the relationship between the elderly's life satisfaction, self-neglect, and psychological well-being and to provide the basis for the development of mediation program to improve the psychological well-being of the elderly. The subjects of this study were 143 elderly persons who living in J city of G province. For data analysis, SPSS WIn 21.0 program was used to calculate real numbers, percentages, the mean values, and standard deviation values, and to conduct t-test, ANOVA, Pearson correlation, and multiple regression analysis. The subjects' psychological well-being was analyzed according to their general characteristics. As a result, their subjective well-being had a positive correlation with their life satisfaction (r=.841, p<.001), and had a negative correlation with their self-neglect (r=-.501, p<.001). As a result of stepwise regression analysis, the factors affecting the psychological well-being of the elderly were life satisfaction (β=.787, p<.001), income source (β=-.114, p=.028), and the explanatory power of these variables was 71.3%. In order to improve the psychological well-being of the elderly through the results of this study, it is necessary to prepare various social systems suitable for the characteristics of the elderly.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.2
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• pp.21-28
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• 2012

The continuous deployment of Urban Traffic Information System (UTIS) in Korea has increased the need for developing more practical applications utilizing the standard functions of UTIS facilities installed on urban arterials beyond its basic applications like gathering traffic data and providing traffic information. The UTIS-based bus signal priority may be one of UTIS-based applications meeting such demands. However, the studies on BSP have not been sufficient for actual field deployment in terms of theories and algorithms so that there have been few actual installations on real urban arterials. Thus, this study was aimed at developing a UTIS-based bus priority signal system and evaluating its effectiveness through a field study. To this end, this study presents the system development processes by dividing the UTIS-based bus priority signal system into hardware and software. In addition, the positive effectiveness of the UTIS-based bus priority signal system was verified through a field application test which was conducted at Gyeonggi Global Trade High School intersection.

• Journal of Korea Port Economic Association
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• v.36 no.1
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• pp.141-164
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• 2020

With business environments around the world facing uncertainty and complexity, companies have focused on supply chain management as one of the essential elements in securing a competitive advantage. Successful supply chain management requires internal efforts to strengthen the core competencies of the company and the integration of individual functions in the supply chain. This study aims to investigate the effect of information sharing between companies on supply chain integration and corporate performance. The research hypothesis established in previous studies was analyzed using structural equation modeling. A total of 723 questionnaire responses were used to test the hypotheses of this study. We found that the integration and sharing of information between companies have a great influence on supply chain integration, which has positive effects on corporate performance at the operational and strategic levels, including finance, market share, and customer satisfaction. The integration of supply chains via information integration and sharing between companies can promote the flow of information, services, goods, and money. Therefore, if information is disconnected between actors in the supply chain, it will lead to negative effects on the management of the entire supply chain. On the other hand, if supply chain actors can share information efficiently in real time on one platform, they can expect to optimize the entire supply chain. Information sharing and integration at the strategic and operational levels play a vital role in supply chain integration, which contributes to achieving a company's performance targets and enhancing its competitiveness.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.351-351
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• 2017

Arbuscular mycorrhizal fungi (AMF) are particular soil fungi that benefit many crops and require a symbiosis with plant roots to survive. In our previous study, there was a positive correlation between AMF root colonization and soybean grain yield in a four-year consecutive winter cover crop-soybean rotational system without phosphorus fertilizer. It is suggested that higher AMF root colonization can be a better solution for improving soybean growth and grain yield in P-limited soil. Our purpose in this study was to test the hypothesis that a P application is the main factor improving soybean growth, P nutrition and grain yield, and the benefit from AMF to soybean P uptake and growth in a P-limited soil. Impact of a P application on AMF root colonization and communities in soybean roots and their potential contribution to soybean growth and P nutrition under a five-year P-unfertilized crop rotational system were investigated over two-years. In this study, four cover crop treatments included 1) wheat (Triticum aestivum); 2) red clover (Trifolium pratense); 3) rapeseed (Brassica napus); and 4) fallow in the crop rotation. The amount of triple superphosphate as a P fertilizer applied rate after cultivation of cover crops was 120 and $360k\;ha^{-1}$ in 2014 and 2015, respectively. Soybean roots were sampled at full-flowering and analyzed for AMF communities using polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) and quantitative real-time PCR (qPCR) techniques. The AMF root colonization in the soybean roots at full bloom stage was significantly influenced by cover crop and P application throughout the two-year rotation. The two-year rotation of different cover crops or fallow impacted the molecular diversity of AMF communities colonizing roots of soybean. Redundancy analysis (RDA) indicated that AMF communities colonizing roots of soybean were significantly different among cover crop rotations. The AMF communities colonizing roots of soybean were clearly influenced by a P application in the two-year trial. Moreover, a P application may have positively impacts on the AMF communities under P-deficit soil due to the continuous cover crop-soybean rotational system without a P fertilizer.

• Applied Chemistry for Engineering
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• v.24 no.3
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• pp.274-278
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• 2013

Automatic transmission fluid (ATF) is used as an automatic transmission in the vehicle or as a characterized fluid for automatic transmission. Recently, vehicle manufacturers usually guarantee for changing fluids over 80000~100000 km mileage or no exchange. However, most drivers usually change ATF below every 50000 km driving distance when driving in Republic of Korea according to a survey from the Korea Institute of Petroleum Management which can cause both a serious environmental contamination by the used ATF and an increase in the cost of driving. In this study, various physical properties such as flash point, pour point, kinematic viscosity, dynamic viscosity at low temperature, total acid number and four-ball test were investigated for both fresh ATF and used ATF after the actual vehicle driving distance of 50000 km and 100000 km. It was shown that most physical properties were suitable for the specification of ATF, but the foam characteristics of the used oil after running 100000 km was unsuitable for the specification of fresh ATF. Therefore, the exchange cycle of ATF every 80000~100000 km driving distance is recommended considering great positive contributions to preventing environmental pollution and reducing driving cost.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.6 no.2
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• pp.112-119
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• 2003

Purpose: Helicobacter pylori infection is thought to be correlated with iron-deficiency anemia (IDA) at puberty. The H. pylori feoB gene, a high-affinity ferrous iron transporter, plays a central role in iron acquisition. This study aims to analyze the H. pylori feoB status according to the presence of antral gastritis with or without IDA. Methods: Fourteen H. pylori-positive patients aged from 10~18 years were categorized into subgroups based on the presence or absence of IDA. Eight patients had IDA, and the other six showed normal hematological findings. Genomic DNA was isolated from cultured H. pylori. Five sets of primers were used for PCR amplification of the feoB gene. The feoB region, 1.93 kb, was generated by linking of the PCR products and sequenced. The feoB gene sequences of H. pylori J99 and 26695 were used to compare with the clinical strains. Sequence comparisons of the feoB regions between the IDA (+) and (-) groups were performed. Results: Sequence analysis of the complete coding region of the feoB revealed 16 sites of polymorphism. Among these, 3 polymorphisms-Glu/Thr254Ala, Ile263Val, and Lys511Gln - were indigenous to Korean strains. Although statistically significant differences appear in 4 sites between IDA (+) and (-), the number of specimens are too low to assess the real differences. Conclusion: The 4 polymorphisms in the feoB gene seem to be related with IDA, but it is unclear yet because of small number of study strains. Further studies are required to prove the correlation of IDA and H. pylori infection.

• Proceedings of the KSRS Conference
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• 2009.03a
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• pp.227-236
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• 2009

This study investigates the characteristics of cloud top brightness temperature (CTBT) of WV and IR1 from MTSAT-1R when lightning strikes in South Korea. For temporal and spatial collocations, lightnings, occurred only within ${\pm}5$ minutes from the six minutes added official satellite observation time (e.g., not 0600 UTC but 0606 UTC, considering the real scan time over South Korea), were selected. And the CTBTs corresponding to lightning spots were determined using the nearest pixel within 5 km. The brightness temperature difference (BTD, defined as WV - IR1) between two channels is negatively large when no lightning occurrs, whereas it increases up to positive values (sometimes, +5 K) and the largest frequency distributes around 225 K and 205 K in lightning cases. The probablistic approach for lightning frequency forecast, presented by Machado et al. (2008) in Southern America, was applied over South Korea and new exponential equations, with high coefficients of determination around 0.95 to 0.99, were developed using two channels' BTDs when lightning strikes. Moreover, a case study on 10th June, 2006, the largest number of lightning occurred between 2002 and 2006, was made. The major finding is that lightning activity is closely related to the dramatic decreases in BT and the increases in BTD (esp., equal to or larger than 0 K). Lightning frequency increases exponentially when BTD increases up to 0 K. Therefore, lightning forecast skill will be improved when the integrated strategy (synoptic background and satellite-based CTBT and BTD) is applied. It is believed that this study contributes to the application of the Korean first geostationary satellite (COMS), scheduled to launch at the end of this year, to severe weather detections.

• Journal of Food Hygiene and Safety
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• v.35 no.2
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• pp.109-117
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• 2020

This study aimed to develop an analytical method for determination of 18 dyes in livestock and fishery products by liquid chromatograph-tandem mass spectrometry (LC-MS/MS). The developed method was validated for linearity, accuracy, limit of quantifications (LOQ) and recovery based on the CODEX guideline (CAC/GL-71). Target matrices (beef, pork, chicken, egg, milk, flatfish, eel, and shrimp) were extracted using acetonitrile (containing 1% of acetic acid) and then, purified with C₁₈ and primary secondary amine (PSA). Calibration linearity was obtained (r²>0.98) and LOQs were 0.002 mg/kg in animal products. The recoveries of dyes were ranged from 63 to 112% and relative standard deviations (RSDs, %) were less than 15%. The residues of 18 dyes were investigated in real samples (n=124) collected from retail markets in South Korea. As a result, a total of seven samples showed positive results for target analytes in fish samples. However, there was no violation according to the maximum residue limits set by the Korean Food Code. The proposed method will be used for routine analysis of dye residues in livestock and fishery products.