• Membrane Journal
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• v.20 no.4
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• pp.342-350
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• 2010

Membrane distillation (MD) is a separation process which higher vapor pressure components are evaporated in mixed liquid solution through hydrophobic membrane with 0.1 or $0.5{\mu}m$ pore size. In this study, direct contact membrane distillation process for hollow fiber module were interpreted numerically using the "COMSOL Multiphysics" software. The variables for the system were temperatures and flow rates of lumen and shell side solutions. The permeate flux increased from 1.0 to $3.8L/m^2{\cdot}hr$ as temperature of the feed solution for lumen increased from 30 to $50^{\circ}C$. However the effect of shell solution temperature on permeate flux was relatively low. Also, the optimum velocity of lumen feed was obtained at 0.15 m/s ($Re_L=135$) by considering MD permeate flux as well as operating pressure loss.

• Bulletin of the Korean Chemical Society
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• v.32 no.1
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• pp.251-262
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• 2011

Human ether-a-go-go related gene (hERG) potassium channel blockade, an undesirable side effect which might cause sudden cardiac death, is one of the major concerns facing the pharmaceutical industry. The purpose of this study is to develop an in silico QSAR model which uncovers the structural parameters of T-type calcium channel blockers to reduce hERG blockade. Comparative molecular similarity indices analysis (CoMSIA) was conducted on a series of piperazine and benzimidazole derivatives bearing methyl 5-(ethyl(methyl)amino)-2-isopropyl-2-phenylpentanoate moieties, which was synthesized by our group. Three different alignment methods were applied to obtain a reliable model: ligand based alignment, pharmacophore based alignment, and receptor guided alignment. The CoMSIA model with receptor guided alignment yielded the best results : $r^2$ = 0.955, $q^2$ = 0.781, $r^2_{pred}$ = 0.758. The generated CoMSIA contour maps using electrostatic, hydrophobic, H-bond donor, and acceptor fields explain well the structural requirements for hERG nonblockers and also correlate with the lipophilic potential map of the hERG channel pore.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.549-552
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• 2008

Corrosion of reinforcing steel is prohibited under normal condition by the alkalinity of the pore water in the concrete. But the probability of steel corrosion becomes higher when the chloride ions are introduced into the concrete. Steel corrosion is decisive factor for the determination of service life of the marine concrete structures because chloride ions are abundant in the sea. In this paper, chloride penetration analysis for the rectangular pier in the marine environment is performed considering the diffusion movement of chlorides. Result reveals that the chloride concentration in the corner bar is higher than that of in the side bar with rectangular pier. Also the time to the specified accumulation of chloride in the corner bar is much shorter than that in the side bar. Because the corrosion initiation time of corner bar is half as much as that of side bar, service life for the rectangular pier in marine environment should be determined with respect to the coner bar.

• Journal of the Korean Geotechnical Society
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• v.21 no.8
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• pp.27-35
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• 2005

Several damages due to large displacement caused by liquefaction have been reported increasingly. Numerical procedures based on effective stress analysis are therefore necessary to predict liquefaction-induced deformation. In this paper, the fully coupled effective stress model called UBCSAND is proposed to simulate pore pressure rise due to earthquake or repeated loadings. The proposed model is a modification of the simple perfect elasto-plactic Mohr-Coulomb model, and can simulate a continuous yielding by mobilizing friction and dilation angles below failure state. Yield function is defined as the ratio of shear stress to mean normal stress. It is radial lines on stress space and has the same shape of Mohr-Columob failure envelope. Plastic hardening is based on an isotropic and kinematic hardening rule. The proposed model always causes plastic deformation during loading and reloading but it predicts elastic unloading. It is verified by capturing direct simple shear tests on loose Fraser River sand.

• Journal of the Korean Geotechnical Society
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• v.15 no.2
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• pp.129-138
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• 1999

This study is performed for the development of a field monitoring and test technique both of self-weight and hydraulic consolidation by which the soil parameters of dredge-reclaimed clay can be obtained effectively. The field monitoring development and tests mentioned above make it possible to reproduce the process of the self-weight consolidation from settling to reclaimed soft ground. The experimental research is mainly focussed on the characteristics of self-weight consolidation of dredged clayey soil. And theoretical study has pointed out the limits in the application of Terzaghi's one dimensional consolidation theory in interpreting reclaimed clayey ground. Furthermore, a finite difference analysis has been made on the basis of Mikasa s self-weight consolidation theory which takes the problems of Terzaghi's theory into consideration. The relationships between specific volume, effective stress, and the coefficient of permeability of Kunsan reclaimed clayey soil have been obtained by laboratory tests. On the other hand, through the field monitoring, pore pressure, total pressure, and water levels have been measured after pouring. The results of these experiments have been analyzed, and compared with those from Terzaghi's method and the finite difference analysis of Mikasa's self-weight consolidation theory. In conclusion, the measured settlements is comparatively consistent with Mikasa's self-weight consolidation theory rather than Terzaghi's consolidation theory.

• Korean Journal of Microbiology
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• v.53 no.1
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• pp.49-54
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• 2017

Sus1 / ENY2 is a tiny conserved protein that is involved in chromatin remodeling and mRNA biogenesis. Sus1 is associated to two nuclear complexes, the transcriptional coactivator SAGA and the nuclear pore associated TREX2. In fission yeast, Schizosaccharomyces pombe, ortholog of Sus1 / ENY2 was identified from the genome database. Tetrad analysis showed that the S. pombe sus1 is not essential for growth. However, deletion of the sus1 gene caused cold-sensitive growth retardation with slight accumulation of $poly(A)^+$ RNA in the nucleus. And the Sus1-GFP protein is localized mainly in the nucleus. Yeast two-hybrid analysis and co-immunoprecipitation experiment showed that Sus1 interacts with Sac3, another subunit of TREX2 complex. These results suggest that S. pombe Sus1 is also involved in mRNA export from the nucleus as a component of TREX-2 complex.

• Journal of the Korean GEO-environmental Society
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• v.11 no.6
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• pp.77-83
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• 2010

In this study, we tried to determine any detrimental effects on water quality when bottom ash obtained from a coal-fired power plant intended to be used as a fill material in construction sites. Physical-chemical properties of bottom ash were determined using proximate analysis, elemental analysis, XRD, and XRF. Classification of bottom ash as a waste material and soil contamination due to the use of bottom ash were performed by Korea waste standard leaching test and soil toxicity test, respectively. Results of leaching tests were compared to the regulations for water quality and groundwater quality and no harmful effects on water quality were found. Most of heavy metals in leachate were below detection limits but trace amount of $Cr^{6+}$ was found. However, concentration of $Cr^{6+}$ was below the regulation criteria. Column leaching tests indicated that concentrations of Pb and Zn were slightly higher than regulations but below regulations within 1 PVE, but concentrations of sulfate were 10 times higher than regulation and thus, the required time to reach regulation was almost 8 PVE.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.11
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• pp.7433-7438
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• 2015

Deactivation characteristics of $V_2O_5/TiO_2$ catalysts were studied for selective catalytic reduction(SCR) of NOx with ammonia in the presence of $SO_2$. Performance of catalyst was investigated for $deNO_x$ activity while changing temperature, $SO_2$ concentration. The activity of catalyst was decreased with the increase of $SO_2$ concentration and reaction time. Also, degree of activity drop was largely decreased with the increase of reaction temperature in the range of $250{\sim}300^{\circ}C$. Physicochemical properties of deactivated catalysts were characterized by BET, XRD, SEM, TPD analysis. According to the analysis results, deactivation phenomena occur due to the relatively high formation of ammonium sulfate salts, which created by unreacted ammonia and water in the presence of $SO_2$. It was revealed that ammonium sulfate cause the pore plogging of support and deposition of active matter.

• 한국환경농학회:학술대회논문집
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• 2011.07a
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• pp.207-222
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• 2011

Relationships between soil saturated hydraulic conductivity ($K_s$) and porosity (${\phi}$) have been developed over many years; however, use of these relationships for evaluating rain-induced seals is limited mainly because of difficulties in estimating seal pore-size characteristics. The objectives of this study were to evaluate the $K_s$ of soil surface seals over a range of thicknesses, where seal thickness was determined using a High-Resolution-Computed-Tomography (HRCT) scanner, and to investigate relationships between $K_s$ and ${\phi}$ of developing seals in samples with equivalent diameters (e.d.) ${\geq}15\;{\mu}m$. A Mexico silt loam soil was packed to a bulk density (${\rho}_b$) of $1.1\;Mg\;m^{-3}$ in cylinders 160-mm i.d. by 160-mm long and subjected to $61-mm\;h^{-1}$ simulated rainfall having a kinetic energy (KE) of $25\;J\;m^{-2}\;min^{-1}$ for 7.5, 15, 30, and 60 min to create a range in seal development. Thicknesses of the seal layers were determined by analysis of HRCT images of seals. The $K_s$ values of the seals were estimated using an effective $K_s$ value ($K_{s-eff}$). The $K_s-{\phi}$ relationship was described by a Kozeny and Carmen equation, $K_s=B{\phi}^n$; where B and n are empirical constants and n = 31. This approach explained 86% of the variation between $K_s$ and ${\phi}$ within the soil seals. Knowledge of surface seal information and hydraulic conductivity can provide useful information to use in management of sites prone to sealing formation.

• Magazine of the Korean Society of Agricultural Engineers
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• v.35 no.2
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• pp.43-56
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• 1993

The laboratory tests are performed on how the liquefaction potential of the sea dike structures on the saturated sand or silty sand seabed could be affected due to earthquake before and after construction results are given as follows ; 1. Earthquake damages to sea dike structures consist of lateral deformation, settlement, minor abnormality of the structures and differential settlement of embankments, etc. It is known that severe disasters due to this type of damages are not much documented. Because of its high relative cost of the preventive measures against this type of damages, the designing engineer has much freedom for the play of judgement and ingenuity in the selection of the construction methods, that is, by comparing the cost of the preventive design cost at a design stage to reconstruction cost after minor failure. 2. The factors controlling the liquefaction potential of the hydraulic fill structure are magnitude of earthquake(max. surface velocity), N-value(relative density), gradation, consistency(plastic limit), classification of soil(G & vs), ground water level, compaction method, volumetric shear stress and strain, effective confining stress, and primary consolidation. 3. The probability of liquefaction can be evaluated by the simple method based on SPT and CPT test results or the precise method based on laboratory test results. For sandy or silty sand seabed of the concerned area of this study, it is said that evaluation of liquefaction potential can be done by the one-dimensional analysis using some geotechnical parameters of soil such as Ip, Υt' gradation, N-value, OCR and classification of soils. 4. Based on above mentioned analysis, safety factor of liquefaction potential on the sea bed at the given site is Fs =0.84 when M = 5.23 or amax= 0.12g. With sea dike structures H = 42.5m and 35.5m on the same site Fs= 3.M~2.08 and Fs = 1.74~1.31 are obtained, respectively. local liquefaction can be expected at the toe of the sea dike constructed with hydraulic fill because of lack of constrained effective stress of the area.