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Studies on Xanthine Oxidase from Bovine Thyroid Glands -[Part 2] Composition and Some Properties- (소의 갑상선에 있는 크산친 옥시다아제에 관한연구 [제2보] 효소의 조성과 특성-)

  • Lee, Hyo-Sa
    • Applied Biological Chemistry
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    • v.21 no.3
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    • pp.137-143
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    • 1978
  • Xanthine oxidase from bovine thyroid glands was found to contain FAD, molybdenum and iron in a ratio 1:0. 36:1. 6. The molecular weight of the thyroid enzyme was similar to that of the milk enzyme when estimated by gel filtration and polyacrylamide gel electrophoresis. The optimum pH for the enzyme activity was 7.8. The pH of the isoelectric point was determined to be 6.2 by electrofocusing. Sodium dodecyl sulfatepolyacrylamide gel electrophoresis experiment indicated that the enzyme was dissociated into subunits and that the molecular weight for the smallest subunit was 65,000 daltons. Absorption spectra were dissimilar between milk and thyroid xanthine oxidase.

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Effects of Scolopendrid Water-Alcohol Extract Injection Applied to the Acupuncture Point on the Neuropathic Pain in Rats (백서(白鼠)에서 오공약침(蜈蚣藥鍼)이 신경병증성(神經病症性) 통증(痛症)에 미치는 영향(影響))

  • Lee, Sam-Ro;Koo, Sung-Tae;Kim, Sung-Nam;Hwang, Woo-Jun;Lee, Geon-Mok;Cho, Nam-Geun;Lim, Kyu-Sang;Kim, Sung-Chul
    • Korean Journal of Acupuncture
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    • v.21 no.2
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    • pp.47-67
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    • 2004
  • Objectives : In the present study, the effect of Scolopendrid Water-Alcohol Extract (SWAE) applied to acupuncture point BL23 (Shinsu) on the neuropathic pain was examined. A common source of persistent pain in humans is the neuropathic pain. Anti-convulsant drugs are used to treat the neuropathic pain. In the oriental medicine, Scolopendrid was used for long time to treat convulsant syndrome and back pain, etc. Methods : On the bases of the Scolopendrid clinical application, the effect of SWAE applied to the acupuncture point was tested in the rat model of neuropathic pain. Neuropathic pain was induced by tight ligation of L5 spinal nerve. When rats developed pain behaviors, One hundred microliter of SWAE was applied into the ipsilateral BL23 point at a dose of 10 mg/ml under enflurane anesthesia. The foot withdraw latency of the hind limb was measured for an indicator of pain level after each manipulation. Results : SWAE injection increased the mechanical threshold of the foot in the rat model of neuropathic pain significantly for the duration of 4h, suggesting a partial alleviation of pain. SWAE applied to BL23 point produced a significant improvement of mechanical sensitivity of the foot lasting for at least 4h. However, neither contralateral BL23 point, ST25 (Chonchu) point, nor LR3 (Taechung) point produce as much increase of mechanical sensitivity as ipsilateral BL23 point. And, this increase of mechanical sensitivity was dose-dependent. The improvement of mechanical threshold was interpreted as an analgesic effect. In addition, the analgesic effect of Scolopendrid 4 mg/kg injection is equivalent to that of gabapentin 50 mg/kg injection. The relations between SWAE-induced analgesia and endogenous nitric oxide(NO), inducible NO synthase (iNOS)/neuronal NO synthase (nNOS) were also examined. Results were turned out that both NO production and nNOS/iNOS protein expression which are increased by nerve injury were suppressed by SWAE injection applied to BL23 point. Conclusions : The data suggest 1) that SWAE produces a potent analgesic effect on the neuropathic pain model in the rat and 2) that SWAE-induced analgesia modulate endogenous NO through the suppression of nNOS/iNOS protein expression.

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Welding Characteristics of 400MPa Grade Hot Rolled H-beam(SHN400) for Building Structure (400MPa급 건축구조용 열간압연 H형강(SHN400)의 용접특성)

  • Kim, Hee-Dong;Yang, Jae-Geun;Lee, Eun-Taik;Kim, Woo-Bum;Oh, Young-Suk
    • Journal of Korean Society of Steel Construction
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    • v.24 no.1
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    • pp.129-136
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    • 2012
  • This study seeks to evaluate the welding characteristics of SHN400 steel, which is suitable for the steel material used in building structures in KS. For this purpose, the Y-groove weld crack test and hardness, tensile, bending, cross tensile, and charpy V notch tests at the welding point were conducted with specimens taken from the highest, the thickest and the commonly used H-beams for girder or beam members. Each test was conducted under the KS test conditions. All tests results satisfied the requirements of KS and the welding requirements for the proper inelastic behavior of structure, indicating that SHN400 can be used for the building structure as a structural material.

A Study on Combustion and Heat Transfer in Premixed Impinging Flames of Syngas(H2/CO)/Air Part II: Heat Transfer Characteristics (합성가스(H2/CO)/공기 예혼합 충돌화염의 연소 및 열전달 연구 Part II : 열전달 특성)

  • Sim, Keunseon;Jeong, Byeonggyu;Lee, Yongho;Lee, Keeman
    • Transactions of the Korean hydrogen and new energy society
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    • v.25 no.1
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    • pp.59-71
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    • 2014
  • An experimental study has been conducted to investigate the heat transfer characteristics of laminar syngas/air mixture with 10% hydrogen content impinging normally to a flat plate of cylinder. Effects of impinging distance, Reynolds number and equivalence ratio as major parameters on heat fluxes of stagnation point and radial direction were examined experimentally by the direct photos and data acquisitions from heat flux sensor. In this work, we could find the incurved flame behavior of line shaped inner top-flame in very closed distance between flat plate and burner exit, which has been not reported from general gas-fuels. There were 3 times of maximum and 2 times minimum heat flux of stagnation point with respect to the impinging distance for the investigation of Reynolds number and equivalence ratio effect. It was confirmed that the maximum heat flux of stagnation point in 1'st and 2'nd peaks increased with the increase of the Reynolds number due to the Nusselt number increment. There was a third maximum rise in the heat flux of stagnation point for larger separation distances and this phenomenon was different each for laminar and turbulent condition. The heat transfer characteristics between the stagnation and wall jet region in radial heat flux profiles was investigated by the averaged heat flux value. It has been observed that the values of averaged heat flux traced well with the characteristics of major parameters and the decreasing of averaged heat flux was coincided with the decreasing trend of adiabatic temperature in spite of the same flow condition, especially for impinging distance and equivalence ratio effects.

Studying the Ephemeris Effect on Position Accuracy Based on Criteria Applied to Baseline Lengths by New MATLAB Program (NMP)

  • Shimaa Farouk;Mahmoud El-Nokrashy;Ahmed Abd-Elhay;Nasr Saba
    • Journal of Astronomy and Space Sciences
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    • v.40 no.3
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    • pp.113-122
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    • 2023
  • Although the Relative Global Navigation Satellite System (GNSS) positioning technique provides high accuracy, it has several drawbacks. The scarcity of control points, the long baselines, and using of ultra-rabid and rabid products increased position errors. This study has designed a New MATLAB Program that helps users automatically select suitable IGS stations related to the baseline lengths and the azimuth between GNSS points and IGS stations. This study presented criteria for the length of the baselines used in Egypt and an advanced estimated accuracy before starting the project. The experimental test studies the performance of the position accuracy related to the relation between three factors: observation session, final, rabid, and ultrarabid products, and the baseline lengths. Ground control point mediates Egypt was selected as a test point. Nine surrounding IGS stations were selected as reference stations, and the coordinates of the tested point were calculated based on them. Baselines between the tested point and the IGS stations were classified regarding proposal criteria. The coordinates of the tested point were obtained in different observation sessions (0.5, 1, 2, 4, 5, 6, 7, 7.5 h). The results indicated that the lengths of the baseline in Egypt were classified short (less than 600 km), medium (600-1,200 km), and long (greater than 1,200 km) and required a minimum observation time of 4, 5, and 7 h to obtain accuracy 10, 19, 48 mm sequentially. The position accuracy was superior for the rapid and the final than the ultra-rapid products by 16%. A short baseline was at the best case; there was a performance in position accuracy with a 57% deduction in observation time compared with the long baseline.

APPLICATION OF HISTOGRAM OUTLIER ANALYSIS ON THE IMAGE DEGRADATION MODEL FOR BEST FOCAL POINT SELECTION

  • Shin, Hyun-Kyung
    • Journal of applied mathematics & informatics
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    • v.27 no.1_2
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    • pp.175-182
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    • 2009
  • Microscopic imaging system often requires the algorithm to adjust location of camera lenses automatically in machine level. An effort to detect the best focal point is naturally interpreted as a mathematical inverse problem [1]. Following Wiener's point of view [2], we interpret the focus level of images as the quantified factor appeared in image degradation model: g = $f{\ast}H+{\eta}$, a standard mathematical model for understanding signal or image degradation process [3]. In this paper we propose a simple, very fast and robust method to compare the degradation parameters among the multiple images given by introducing outlier analysis of histogram.

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COMMON FIXED POINT THEOREMS FOR MULTIVALUED MAPS SATISFYING CONTACTIVE CONDITIONS OF AN INTEGRAL TYPE

  • Cho, Seong-Hoon;Bae, Jong-Sook
    • Journal of applied mathematics & informatics
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    • v.28 no.1_2
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    • pp.397-409
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    • 2010
  • We prove the existence of common fixed points for multivalued maps satisfying a contractive condition of an integral type. Our results are extent ions of results of Feng and Liu[Y. Feng, S. Liu, Fixed point theorems for multi-valued contractive mappings and multi-valued Caristi type mappings, J. Math. Anal. Appl. 317(2006), 103-112] and also, extent ions of results of Daffer and Kaneko[P. Z. Daffer, H. Kaneko, Fixed points of generalized contractive multi-valued map pings, J. Math. Anal. Appl. 192(1995), 655-666]. A main result in Feng and Liu[Y. Feng, S. Liu, Fixed point theorems for multi-valued contractive mappings and multi-valued Caristi type mappings, J. Math. Anal. Appl. 317(2006), 103-112] is proved under necessary additional conditions.

A Study on the Constrained Dispatch Scheduling Using Affine Scaling Interior Point Methdod (Affine Scaling Interior Point Method를 이용한 제약급전계획에 관한 연구)

  • Kim, Kyung-Min;Han, Seok-Man;Kim, Kang-Won;Park, Jung-Sung;Chung, Koo-Hyung;Kim, Bal-Ho H.
    • Proceedings of the KIEE Conference
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    • 2005.07a
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    • pp.858-860
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    • 2005
  • This paper presents an Optimal Power Flow (OPF) algorithm using Interior Point Method (IPM) to swiftly and precisely perform the five minute dispatch. This newly suggested methodology is based on Affine Scailing Interior Point Method (AS IPM), which is favorable for large-scale problems involving many constraints. It is also eligible for OPF problems in order to improve the calculation speed and the preciseness of its resultant solutions. Lastly, this paper provides a relevant case study to confirm the efficiency of the proposed methodology.

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Optimal Power Flow Using Affine Scaling interior Point Method (Affine Scaling Interior Point Method를 이용한 최적조류계산)

  • Kim, Kyung-Min;Park, Jung-Sung;Han, Seok-Man;Chung, Koo-Hyung;Kim, Bal-Ho H.
    • Proceedings of the KIEE Conference
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    • 2005.11b
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    • pp.156-158
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    • 2005
  • This paper presents an Optimal Power Flow (OPF) algorithm using Interior Point Method (IPM) to swiftly and precisely perform the five minute dispatch. This newly suggested methodology is based on Affine Sealing Interior Point Method (AS IPM), which is favorable for large-scale problems involving many constraints. It is also eligible for OPF problems in order to improve the calculation speed and the preciseness of its resultant solutions. Big-M Method is also used to improve the solution stability. Finally, this paper provides a relevant case study to confirm the efficiency of the proposed methodology.

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Slicing a Point Cloud (점군 절단 알고리즘)

  • Park, Hyeong-T.;Chang, Min-H.;Park, Sang-C.
    • Korean Journal of Computational Design and Engineering
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    • v.12 no.2
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    • pp.146-152
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    • 2007
  • Presented in the paper is an algorithm to generate a section curve by slicing a point cloud which may include tens of thousands of points. Although there are couple of previous results, they are very sensitive on the density variations and local noising points. In the paper, three technological requirements are identified; 1) dominant point sampling, 2) avoiding local vibration, and 3) robustness on the density changes. To satisfy these requirements, we propose a new slicing algorithm which is based on a node-circle diagram. The algorithm has been implemented and tested with various examples.