• 제목/요약/키워드: plasma components

검색결과 536건 처리시간 0.032초

Antidiabetic and Hypolipidemic Effects of Collybia confluens Mycelia Produced by Submerged Culture in Streptozotocin-Diabetic Rats

  • Yang, Byung-Keun;Jeong, Sang-Chul;Lee, Hyun-Ji;Sohn, Dong-Hwan;Song, Chi-Hyun
    • Archives of Pharmacal Research
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    • 제29권1호
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    • pp.73-79
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    • 2006
  • This investigation was undertaken to study the effects of oral administration (3 weeks) of Collybia confluens mycelial powder (CCMP) produced by a submerged culture on plasma glucose and other biochemical parameters in streptozotocin (STZ)-induced diabetic rats. Antidiabetic and hypolipidemic effects were proportionally increased with the increasing concentration of the CCMP for oral administration. The CCMP, at the dose of 400 mg/kg BW, substantially reduced the plasma glucose level by as much as 33.1 % as compared to the STZ-induced diabetic rats group. It also lowered the plasma total cholesterol, triglyceride, and low density lipoprotein (LDL) cholesterol by 22.9%, 19.9%, and 37.3%, respectively. The levels of total cholesterol and triglyceride in liver were reduced to the extent of by 13.5% and 18.8%, and the activity of alanine transaminase (ALT) and aspartate transaminase (AST) was decreased by 48.8% and 37.2%, respectively, under the influence of CCMP. The general components of CCMP were found to contain 26.18% carbohydrate, 3.67% crude ash, 4.02% crude fat, 22.55% crude protein, and 43.58% dietary fiber. The amino acid composition of the CCMP was also analyzed in detail.

Analysis of Vasopressin-Induced $Ca^{2+}$ Increase in Rat Hepatocytes

  • Kim, Hyun-Sook;Fumikazu-Okajima;Im, Dong-Soon
    • Archives of Pharmacal Research
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    • 제26권1호
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    • pp.64-69
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    • 2003
  • To analyze vasopressin-induced $Ca^{2+}$ increase in liver cells, rat hepatocytes were isolated and attached to collagen-coated cover slips. Using fura-2, a $Ca^{2+}$-sensing dye, changes in intracellular $Ca^{2+}$ concentration by vasopressin were monitored. Results in this communication suggested that vasopressin-induced $Ca^{2+}$ increase were composed of both $Ca^{2+}$ release from internal $Ca^{2+}$ stores and influx from the plasma membrane. The $Ca^{2+}$ influx consisted of two distinguishable components. One was dependent on the presence of vasopressin and the other was not. SK&F96365 blocked vasopressin-induced $Ca^{2+}$ influx in a dose-dependent manner. Vasopressin-induced $Ca^{2+}$ release from internal stores diminished in a primary culture of hepatocytes according to the culture time. However, changes in vasopressin-induced $Ca^{2+}$ influx across the plasma membrane differed from changes in the $Ca^{2+}$ release from internal stores, suggesting two separate signalings from receptor activation to internal stores and to the plasma membrane.

Analysis on an Oxidation-Reduction Reaction of Photocatalytic Plasma Complex Module

  • KIM, Young-Do;KWON, Woo-Taeg
    • 웰빙융합연구
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    • 제5권2호
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    • pp.21-27
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    • 2022
  • Purpose: This study is about photocatalytic technology and plasma oxidation-reduction technology. To the main cause of exposure to odor pollution, two deodorization techniques were applied to develop a module with higher removal efficiency and ozone reduction effect. Research design, data and methodology: A composite module was constructed by arranging two types of dry deodorization equipment (catalyst, adsorbent) in one module. This method was designed to increase the responsiveness to the components of complex odors and the environment. standard, unity, two types of oxidizing photo-catalyst technology and plasma dry deodorization device installed in one module to increase the potential by reduction to 76% of ozone, 100%, and 82%. Results: The complex odor disposal efficiency was 92%. Ammonia was processed with 50% hydrogen sulfide and 100% hydrogen sulfide, and ozone was 0.01ppm, achieving a target value of 0.07ppm or less. The combined odor showed a disposal efficiency of 93%, ammonia was 82% and hydrogen sulfide was 100% processed, and ozone achieved a target value of 0.07 ppm or less. Conclusions: Ozone removal efficiency was 76% by increasing Oxidation-Reduction Reaction(ORR). The H2S removal efficiency of the deodorizer was higher than that of the biofilter system currently used in sewage disposal plants.

Lifetime Enhancement of Aerospace Components Using a Dual Nitrogen Plasma Immersion ion Implantation Process

  • Honghui Tong;Qinchuan Chen;Shen, Li-Lu;Yanfeng Huo;Ke Wang;Tanmin Feng;Lilan Mu;Jun Zha;Paul K. Chu
    • Journal of Korean Vacuum Science & Technology
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    • 제6권2호
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    • pp.62-66
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    • 2002
  • Hydraulic pumps are used to control the landing wheels of aircrafts, and their proper operation is vital to plane safety It is well hewn that adhesive wear failure is a major cause of pump failure. A dual nitrogen plasma immersion ion implantation process calling for the implantation of nitrogen at two different energies and doses has been developed to enhance the surface properties of the disks in the pumps. The procedures meet the strict temperature requirement of <200$^{\circ}C$, and after the treatment, the working lifetime of the pumps increases by more than a factor of two. This experimental protocol has been adopted by the hydraulic pump factory as a standard manufacturing procedure.

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Cyclic 증착방법에 의해성장된 다이아몬드 박막의 cathodoluminescence 특성에 관한 연구 (Cathodoluminescence Study of Diamond Films Grown by Cyclic Deposition Method)

  • 서수형;신완철;박진석
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2001년도 추계학술대회 논문집 전기물성,응용부문
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    • pp.12-15
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    • 2001
  • Polycrystalline diamond films are deposited by cyclic method. modulating the $H_2$ Plasma and $CH_4+H_2$ plasma during the growth step. Diamond quality is evaluated by FWHM and $I_D/I_G$ ratio obtained from Raman spectroscopic analysis. Structural defects and impurities generated during the growth step are characterized by cathodoluminescence, and the variations between band-A(430 nm) line and nitrogen-related(578 nm) line are investigated as a function of $T_E/T_G$. Furthermore, the correlations between preferential orientation. film morphologies and CL characteristics are also investigated.

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KSTAR 초전도자석 지지각 시작품재작 및 구조시험 (KSTAR Superconducting Magnet Supporting Post Prototype Manufacturing and Structural Load Test)

  • 허남일;이영신
    • 한국초전도ㆍ저온공학회논문지
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    • 제3권1호
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    • pp.45-49
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    • 2001
  • A magnet supporting post installed between the lower TF coil tooled by 4.5 K supercritical helium and the cryostat base is one of the most important components of the superconducting magnet supporting structure for KSTAR Tokamak. This structure should be flexible to absorb thermal shrink of the magnet and also should be rigid to support the magnet weight and the Plasma disruptions load. The Post was designed with stainless steel 316LN and CFRP that have low thermal conductivity and high structural strength at low temperature. In order to verify the possibility of fabrication and the structural safety. a whole scale prototype of the KSTAR magnet supporting post was manufactured and tested. Static and compressive cyclic load tests under the maximum Plasma vertical disruption load and the magnet dead weight were performed. The teat results showed that the magnet supporting post of KSTAR Tokamak was possible to manufacture and structurally rigid.

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Association between Genetic Variation in the Human Factor Ⅶ Gene and Essential Hypertension in Korean Population

  • Shin, Jung-Hee;Kang, Byung-Yong;Lee, Kyung-Ho;Lee, Chung-Choo;Kim, Ki-Tae
    • 한국환경성돌연변이발암원학회지
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    • 제21권2호
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    • pp.106-112
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    • 2001
  • In view of the effect of factor Ⅶ as a risk factor for essential hypertension, we investigated the length (I/D) polymorphism at position 323 promoter region and exon 8-Msp I RFLP of the human factor Ⅶ gene in the Korean patients with essential hypertension and normal controls. There were no significant differences in the allele, genotype and haplotype frequencies of these polymorphisms between normotensive and essential hypertensive subjects. The significant linkage disequilibrium was however, detected between two polymorphic sites. The Msp I RFLP and I/D polymorphism were also significantly associated with plasma triglyceride (TG) levels. Therefore, our results suggest that the significant association between two genetic variations in the human factor Ⅶ gene and plasma TG level may reflect the potential role of human factor Ⅶ gene as one of the genetic components for cardiovascular risk.

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Multifactorial Regulation of G Protein-Coupled Receptor Endocytosis

  • Zhang, Xiaohan;Kim, Kyeong-Man
    • Biomolecules & Therapeutics
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    • 제25권1호
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    • pp.26-43
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    • 2017
  • Endocytosis is a process by which cells absorb extracellular materials via the inward budding of vesicles formed from the plasma membrane. Receptor-mediated endocytosis is a highly selective process where receptors with specific binding sites for extracellular molecules internalize via vesicles. G protein-coupled receptors (GPCRs) are the largest single family of plasma-membrane receptors with more than 1000 family members. But the molecular mechanisms involved in the regulation of GPCRs are believed to be highly conserved. For example, receptor phosphorylation in collaboration with ${\beta}$-arrestins plays major roles in desensitization and endocytosis of most GPCRs. Nevertheless, a number of subsequent studies showed that GPCR regulation, such as that by endocytosis, occurs through various pathways with a multitude of cellular components and processes. This review focused on i) functional interactions between homologous and heterologous pathways, ii) methodologies applied for determining receptor endocytosis, iii) experimental tools to determine specific endocytic routes, iv) roles of small guanosine triphosphate-binding proteins in GPCR endocytosis, and v) role of post-translational modification of the receptors in endocytosis.

Reconstruction of the Electron Density Profile in O-mode Ultrashort Pulse Reflectometry using a Two-dimensional Finite Difference Time Domain

  • Roh, Young-Su
    • 조명전기설비학회논문지
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    • 제27권7호
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    • pp.52-58
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    • 2013
  • The two-dimensional finite difference time domain algorithm is used to numerically reconstruct the electron density profile in O-mode ultrashort pulse reflectometry. A Gaussian pulse is employed as the source of a probing electromagnetic wave. The Gaussian pulse duration is chosen in such a manner as to have its frequency spectrum cover the whole range of the plasma frequency. By using a number of numerical band-pass filters, it is possible to compute the time delays of the frequency components of the reflected signal from the plasma. The electron density profile is reconstructed by substituting the time delays into the Abel integral equation. As a result of simulation, the reconstructed electron density profile agrees well with the assumed profile.

Improved Dual-Path Energy Recovery Circuit using a Current Source and a Voltage Source for High Resolution and Large-Sized Plasma Display Panel

  • Yi, Kang-Hyun;Moon, Gun-Woo
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2008년도 하계학술대회 논문집
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    • pp.544-546
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    • 2008
  • An improved dual-path energy recovery circuit (ERC) using a current source and a voltage source for plasma display panel (PDP) is proposed. The proposed ERC uses the voltage source to charge a panel and the current source to discharge the panel. Thus, the proposed circuit can make the panel charge to $V_S$ and discharge to 0V, fully and it is possible to achieve zero voltage switching (ZVS) of all switches in H-bridge inverter and zero current switching (ZCS) of all switches in the ERC. Moreover, it has less conduction and switching loss in ERC devices by the dual energy recovery paths for charging and discharging the panel. Furthermore, it has features of canceling the gas discharge current, high performance and the low cost ERC components. The operation principle and features of the proposed ERC are presented in detail and verified with 42-inch SD PDP.

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