• Proceedings of the Korean Society of Marine Engineers Conference
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• 2001.05a
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• pp.207-212
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• 2001

In this paper, a method to be able to decide the possible maximum gain of P, PI control for the retarded processes under stable condition is proposed. At first, adjustable parameter set causing stability limit are obtained based on the frequency domain condition which makes the roots of transfer function locate on the $j\omega$ axis. And the cut-in frequency $\omega{_p}$ to bring the parameter set to P control from PI control is derived by an equation with 2 parameters L and $T_m$ given, then $\omega{_p}$ is used to compute the maximum gain with stable condition. For the calculation, the controlled process of first order system with time delay element is introduced and all parameters are presumed to be time invariant.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.77.1-77
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• 2001

In this paper, we propose a control scheme for improving the performance of a conventional Proportional-Integral (PI) controller for Active Queue Management (AQM) supporting TCP flows. When the PI controller is used for AQM, the windup phenomenon of the integral action causes the performance degradation. Therefore we model AQM as a system with a saturator and apply anti-windup methods to the PI controller for AQM. We compare the performances of anti-windup algorithm with the conventional PI controller through ns simulations. The simulation results show that the PI controller with anti-windup method performs better than the conventional PI controller.

• Journal of Integrative Natural Science
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• v.9 no.1
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• pp.41-61
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• 2016

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide. Phosphoinositide 3-kinases (PI3Ks) play important role in Non-Small Cell Lung Cancer. PI3Ks constitute a lipid kinase family which modulates the function of numerous substrates involved in the regulation of cell survival, cell cycle progression and cellular growth. Herein, we describe the ligand based pharmacophore combined with molecular docking studies methods to identify new potent PI3K inhibitors. Several pharmacophore models were generated and validated by Guner-Henry scoring Method. The best models were utilized as 3D pharmacophore query to screen against ZINC database (Chemical and Natural) and the retrieved hits were further validated by fitness score, Lipinski's rule of five. Finally four compounds were found to have good potential and they may act as novel lead compounds for PI3K inhibitor designing.

• Journal of Korean Society for Quality Management
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• v.46 no.4
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• pp.863-876
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• 2018

Purpose: There are several KPI(key performance indicators) models: BSC(balanced scorecard), IPOO(Input-process-output-outcomes) indicators, QCDP(quality-cost-delivery-productivity) indicators. This paper analyze these models and gives some suggestions to help the effective usage of KPI. Methods: This paper reviews and summarize the criteria to evaluate the PI(performance indicators) through literature review. Evaluation and analysis on the PI factors of the KPI developing models is performed by the criteria. Results: Criteria to evaluate the PI, which can be used to evaluate the goodness of PI is suggested. This paper also proposes some suggestions for the KPI models and their factors for the effective development of PI in the organization. Conclusion: This research will help the managers to develop and select useful PI and KPI for their business and processes.

• Proceedings of the Korea Society of Design Studies Conference
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• 2003.05a
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• pp.252-253
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• 2003

• Transactions on Electrical and Electronic Materials
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• v.9 no.6
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• pp.243-246
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• 2008

We have studied the liquid crystal (LC) alignment, the pretilt angle generation, and the annealing behavior for a nematic liquid crystal (NLC) on the homogeneous polyimide (PI) surfaces by using the rubbing method and the ion beam (IB) method. An excellent LC alignment of the NLC on the PI surface with rubbing and IB irradiation were observed. The pretilt angle of NLC on the homogeneous PI surface for the rubbing method is decreased from $4.5^{\circ}$ to $3.5^{\circ}$ as rubbing time is increased, that of the for the IB irradiation method is decreased from $0.5^{\circ}$ to $0.1^{\circ}$ as the time of IB irradiation is increased. After the annealing, the pretilt angles of the rubbed PI surfaces increased up to $4^{\circ}$, these of the IB irradiated PI surfaces little increased. It is considered the side chain of the rubbed PI show the its abilities of the original capacities, while the side chain of the IB irradiated PI cannot show the its abilities of the original capacities due to the IB has already destroyed the side chain of the PI.

• Journal of Electrical Engineering and Technology
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• v.12 no.1
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• pp.78-90
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• 2017

This paper presents the design of closed loop controllers operating a single-phase AC-DC three-level converter for improving power quality at AC mains. Closed loop inhibits outer voltage controller and inner current controller. Simulations of three level converter with three different voltage and current controller combinations such as PI-Hysteresis, Fuzzy-Hysteresis and Fuzzy tuned PI-Hysteresis are carried out in MATLAB/Simulink. Performance parameters such as input power factor and source current total harmonic distortion (THD) are considered for comparison of the three controller combinations. The fuzzy-tuned PI voltage controller with hysteresis current controller combination provides a better result, with a source-current THD of 0.93% and unity power factor without any source side filter for the three level converter. For load variations of 25% to 100%, a THD of less than 5% is obtained with a maximum value of only 1.67%. Finally, the fuzzy-tuned PI voltage with hysteresis controller combination is implemented in a Xilinx Spartan-6 XC6SLX25 FPGA board for experimental validation of power quality enhancement. A prototype 100 W, 0-24-48 V as output converter is considered for the testing of controller performance. A source-current THD of 1.351% is obtained in the experimental study with a power factor near unity. For load variations of 25% to 100%, the THD is found to be less than 5%, with a maximum value of only 2.698% in the experimental setup which matches with the simulation results.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.2
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• pp.257-267
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• 2001

This paper presents a design for a single-layer feeder waveguide array using $\pi$-junctions with the inductive wall. The feed structure consists of a single waveguide placed on the same layer as radiating waveguide and is characterized by the unit divider, called a $\pi$-junction. This $\pi$-junction with an inductive wall splits part of the power into two branchs waveguide through one coupling window, and can excite densely arrayed waveguide at equal phase and amplitude. The power dividing characteristics of the cascade of $\pi$ -junctions are analyzed by Galerkin's method of moments. The numerical results show reasonable agreement with the experimental results. From the optimum simulation results based on the feeder waveguide using $\pi$-junction, we obtained the scattering matrices of the feeder divided power at 3.95 GHz.

• 한국약용작물학회:학술대회논문집
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• 2011.09a
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• pp.31-45
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• 2011

The amyloid ${\beta}$-peptide ($A{\beta}$), which originates from the proteolytic cleavage of amyloid precursor protein (APP), plays a central role in the pathogenesis of Alzheimer's disease (AD). Mounting evidence indicates that different species of $A{\beta}$, such as $A{\beta}$ oligomers and fibrils, may contribute to AD pathogenesis via distinct mechanisms at different stages of the disease. Importantly, elevation and accumulation of soluble $A{\beta}$ oligomers closely correlate with cognitive decline and/or disease progression in animal models of AD. In agreement with these studies, oligomers of $A{\beta}$ have been shown to directly affect synaptic plasticity, a neuronal process that is known to be essential for memory formation. Our previous studies showed that $A{\beta}$ induces the breakdown of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), a phospholipid that regulates key aspects of neuronal function. PI(4,5)P2 breakdown was found to be a key step toward synaptic and memory dysfunction in a mouse model of AD. To this end, we seek to identify small molecules that could elevate the levels of PI(4,5)P2 and subsequently block $A{\beta}$ oligomer-induced breakdown of PI(4,5)P2 and synaptic dysfunction.. We found that (20S)Rg3, an active triterpene glycoside from heat-processed ginseng, serves as an agonist for phosphatidylinositol 4-kinase IIalpha (PI4KIIalpha), which is a lipid kinase that mediates a rate-limiting step in PI(4,5)P2 synthesis. Consequently, (20S)Rg3 stimulates PI(4,5)P2 synthesis by directly stimulating the activity of PI4KIIalpha. Interestingly, treatment of a mouse model of AD with (20S)Rg3 leads to reversal of memory deficits. Our data suggest that the PI(4,5)P2-promoting effects of (20S)Rg3 may help mitigate the cognitive symptoms associated with AD.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.21 no.5
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• pp.25-31
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• 2007

This paper presents a comparison of different current controller response characteristics of SRM. The most common current controllers of the SRM is hysteresis type. The hysteresis controller is easy to implement and fast current control response, but has the inherent disadvantage of switching frequency variations. The other common type of current controller is PI scheme. The design of a classical PI current controller with fixed parameters for SRM is not an easy task due to the extreme nonlinear characteristics. In this paper, some linearization technique is used for design of PI current controller. Experimental results of 1-hp SRM are presented for the basic reference data which can be used to select the proper current control scheme according to the applications.