• 대한간호학회지
• /
• 제30권4호
• /
• pp.917-931
• /
• 2000

This study was to provide understanding for the juvenile problem of drug brought about by industrialization, and the importance people that we should take a role in helping to resolve the problem. The purpose of this study lies in approaching the effective methods to prevent Korean adolescents from being involved in drug by examining the factors of their experience. The method of this study is designed to grasp the adolescents' drug experience, its meaning, its structure and the nursing intervention ways. By applying a phenomenological approach which is based on a qualitative research method, the researchers hoped to reveal key data in each group. It has been carried on from October 1998 until September 1999 with sample of 5 adolescent inmates in K mental hospital located in Seoul. The data were collected by sereous personal deep interviews and observations. Collected data were analyzed according to the phenomenological method suggested by Giorgi. The results of this study are as follows: First, pleasure seeking: curiosity, joy, and fun; Second, affiliation: formation of clique with the same age; Third, escape from reality: loneliness, emptiness, heroic mind, self- confidence, self-absorption, and comfort; Forth, feeble- mindedness: anxiety, fear, and temptation; Fifth, psychological unadaptation: wandering, forfeiture, and incompetence; Sixth, physical counteraction: headache, vomiting, loss of memory, loss of appetite and loss of sensibility; Seventh, psychological confusion: illusion, auditory hallucination and dream; Eighth, recovery of self-consciousness: repentance, desire and awareness This study results in the following suggestions of the nursing intervention 1. To cultivate a wholesome game culture for the adolescents. 2. To make up the group activities so that the adolescents can establish their sense of identity through a variety of group counseling program. 3. To foster the capability to cope with the change in the process of social accommodation. 4. To enforce the social life skill for the adolescents. 5. To practice the systematic education about drug use. 6. To develop the social education programs. 7. To help the adolescents build up their sense of identity by applying the adolescent cure programs. Above all, it is necessary that school and community as well as home should establish the educational environment paying special concern and consideration to the adolescents.

• The Korean Journal of Pain
• /
• 제29권3호
• /
• pp.153-157
• /
• 2016

Tapentadol is a novel oral analgesic with a dual mode of action as an agonist of the ${\mu}$-opioid receptor (MOR), and as a norepinephrine reuptake inhibitor (NRI) all in a single molecule. Immediate release (IR) tapentadol shows its analgesic effect quickly, at around 30 minutes. Its MOR agonistic action produces acute nociceptive pain relief; its role as an NRI brings about chronic neuropathic pain relief. Absorption is rapid, with a mean maximal serum concentration at 1.25-1.5 h after oral intake. It is present primarily in the form of conjugated metabolites after glucuronidation, and excretes rapidly and completely via the kidneys. The most common adverse reactions are nausea, dizziness, vomiting, and somnolence. Constipation is more common in use of the ER formulation. Precautions against concomitant use of central nervous system depressants, including sedatives, hypnotics, tranquilizers, general anesthetics, phenothiazines, other opioids, and alcohol, or use of tapentadol within 14 days of the cessation of monoamine oxidase inhibitors, are advised. The safety and efficacy have not been established for use during pregnancy, labor, and delivery, or for nursing mothers, pediatric patients less than 18 years of age, and cases of severe renal impairment and severe hepatic impairment. The major concerns for tapentadol are abuse, addiction, seeking behavior, withdrawal, and physical dependence. The presumed problem for use of tapentadol is to control the ratio of MOR agonist and NRI. In conclusion, tapentadol produces both nociceptive and neuropathic pain relief, but with worries about abuse and dependence.

• 보건교육건강증진학회지
• /
• 제9권2호
• /
• pp.103-120
• /
• 1992

The purpose of this study was designed for the model development of curriculum of school health education including learning-teaching method, through analysis of results compared between a regular schedule health instruction and irregular health education. And this study is an attempt to give fundamental information for establishing of school health subject as the concept and scope of the school health subject is still not recognized and accepted satisfactorily in Korea. The data were collected by questionnaire from middle school girls and were carried out from 1989 to 1991. The major results obtained from this study were as follows: A Analysis of the case of school health. instruction 1. The responses of students about health eaducation : The positive rate of answers on the 'Health education is very important subject' was 91.2%, and on the 'I can maintain well healthful life : int of selfcare' was 87.1%. 2. The condition on knowledge, attitude and practice about health education: Education group had higher scores than comparison group about all most of questions, especially sex-education and drug abuse prevention education. 3. All the case of disease early founded out during the health instruction were children disease such as bone-tumor, lymphoma, hydrocephalus, and leukemia. B. Model development of school health education 1. Component of the health education subject (1) Healthful Life → Personal Health (2) Physical anatomy and Prevention of disease → Community Health (3) Growth and Development(sex education) → Community Health (4) Environment and Health → Community Health (5) Previntion of drug abuse → Human Health (6) Safety life → Human Health 2. Leanning - teaching method of health instruction (1) A Model of leaning-teaching method : A regular circulating health instruction by the component health subject for 2 hours a month. (2) B Model of leaning-teaching method : A regular schedule health education for hour a week.

• 한국가족복지학
• /
• 제54호
• /
• pp.225-262
• /
• 2016

본 연구의 목적은 아동보호서비스 개입사례의 재학대 특성을 확인하는 것이다. 이를 위해 국가아동학대정보시스템에 접근하여 2012년에 신고 접수된 전수를 추출하였고 이들 사례 중 아동학대로 판정된 사례를 중심으로 2014년까지 총 3년간의 데이터를 수집하여 해당기간 내 재학대가 발생한 사례들의 특성을 확인하였다. 재학대 특성은 생존분석을 통해 재학대 발생 시점 및 빈도를 중심으로 살펴보았다. 분석결과, 2012년에 학대판정을 받은 5,542사례 중 323사례가 이후 3년 이내에 재학대를 기록하였다. 대부분의 사례(93.5%)가 1회의 재학대를 기록하였지만 2회의 재학대를 기록한 사례도 21사례로 확인되었다. 또한 학대로 판정된 이후 1개월 이내에 가장 많은 재학대가 발생하였고, 이전 아동보호서비스 연루 유무, 중복학대 유무, 신체학대 포함 여부, 서비스 제공 유형 등에 따라 재학대 발생 시기 및 빈도가 다르게 나타났다. 아동의 연령 및 문제행동 수, 학대행위자의 스트레스 및 사회적 고립, 가족구성원인 학대행위자, 이전 아동보호서비스 연루 기록, 재신고 총 횟수 증가 등은 이후의 재학대 발생과 관련되었다. 본 연구는 이러한 분석결과를 토대로 아동학대의 재학대 예방을 위한 정책적, 실천적 함의를 논하고 관련 제언을 제시하였다.

• International Journal of Computer Science & Network Security
• /
• 제22권2호
• /
• pp.424-435
• /
• 2022

When the owners of the intellectual property rights of digital content have lost control over it in the digital environment, there emerged fears that the intellectual property laws, especially copyright law, would not be effective as in the material (Offline ) world. The reason is that the digital environment helps to reproduce copies in high quality and at almost no cost, while copyright law protection has been limited to programs embedded in CDs. According to copyright laws, the owner of the program did not have the right to prevent buyers of the initial physical copy of the program from copying and reselling it to more than one individual without the permission of the original owner. As a result, business owners have invented the idea of licensing digital content and programs instead of selling them. They set out terms that serve their commercial interests regardless of their abuse to intellectual property laws or even the rules of the traditional contract to sell a material property. The abuse has resulted from the way those terms are concluded and the heavy rules that are unfair to consumer rights. Therefore, business owners insisted on dealing with the website and its programs and digital content as material property. Here raises the question of whether the website and its digital content are subject to the protection of copyright law or the rules of the traditional contract or licensing contracts. As the answer to this question affects the protection of consumer rights, is it possible to find a balance between it and the protection of the owners of digital programs' rights.That is what we will discuss in this paper.

• Biomolecules & Therapeutics
• /
• 제30권3호
• /
• pp.238-245
• /
• 2022

Previous reports have demonstrated that genetic mechanisms greatly mediate responses to drugs of abuse, including methamphetamine (METH). The circadian gene Period 2 (Per2) has been previously associated with differential responses towards METH in mice. While the behavioral consequences of eliminating Per2 have been illustrated previously, Per2 overexpression has not yet been comprehensively described; although, Per2-overexpressing (Per2 OE) mice previously showed reduced sensitivity towards METH-induced addiction-like behaviors. To further elucidate this distinct behavior of Per2 OE mice to METH, we identified possible candidate biomarkers by determining striatal differentially expressed genes (DEGs) in both drug-naïve and METH-treated Per2 OE mice relative to wild-type (WT), through RNA sequencing. Of the several DEGs in drug naïve Per2 OE mice, we identified six genes that were altered after repeated METH treatment in WT mice, but not in Per2 OE mice. These results, validated by quantitative real-time polymerase chain reaction, could suggest that the identified DEGs might underlie the previously reported weaker METH-induced responses of Per2 OE mice compared to WT. Gene network analysis also revealed that Asic3, Hba-a1, and Rnf17 are possibly associated with Per2 through physical interactions and predicted correlations, and might potentially participate in addiction. Inhibiting the functional protein of Asic3 prior to METH administration resulted in the partial reduction of METH-induced conditioned place preference in WT mice, supporting a possible involvement of Asic3 in METH-induced reward. Although encouraging further investigations, our findings suggest that these DEGs, including Asic3, may play significant roles in the lower sensitivity of Per2 OE mice to METH.

• 한국직업건강간호학회지
• /
• 제26권3호
• /
• pp.184-196
• /
• 2017

Purpose: We investigated the effects of emotional labor and workplace violence on various physical and mental health outcomes among female workers. Methods: We obtained data from 24,760 female workers who participated in the 4th Korean Working Conditions Survey (2014). Hierarchical logistic regression analysis was used to analyze the relationships. Results: Female emotional workers were more exposed to workplace violence than were female non-emotional workers. Verbal abuse was the most common type of workplace violence. Logistic regression analyses revealed that (1) emotional labor was significantly associated with higher odds of having musculoskeletal or abdominal pain (physical health outcomes), along with overall fatigue (a mental health outcome), and (2) workplace violence experiences were significantly associated with higher odds of musculoskeletal pain, headache/eye strain, abdominal pain, depression/anxiety disorder, overall fatigue, and insomnia/sleep disturbance, after controlling for covariates. Conclusion: This study demonstrated that both emotional labor and workplace violence have negative effects on physical and mental health. However, workplace violence experience has a stronger negative impact on health outcomes than does emotional labor alone. A management system to eradicate workplace violence and programs aimed at managing emotional labor are urgently needed at the organizational level.

• Biomolecules & Therapeutics
• /
• 제19권1호
• /
• pp.45-51
• /
• 2011

These experiments were designed to use typical makers from behaviors and molecular basis in addicted animals of morphine and cocaine. Morphine has been widely abused with a high physical dependence liability. Morphine withdrawal activates the intracellular cAMP signaling pathway and further leads to changes in the expression of the cAMP response element binding protein (CREB), which may be important to the development and expression of morphine dependence. From these experiments, repeated morphine (10 mg/kg, twice per day for 7 days) developed physical dependence. Withdrawal signs were precipitated by naloxone and also increased the expression of the CREB. In addition, repeated exposure of cocaine (15 mg/kg) to mice develops locomotor sensitization and produced lasting behavioral sensitivity. Cocaine- and amphetamine-regulated transcript peptide (CART) peptide was up-regulated by repeated administration of cocaine in the striatum. Therefore, repeated morphine induced the development of physical dependence and increased pCREB. In addition, repeated cocaine induced locomotor sensitization and over-expressed CART peptide. In conclusion, the development of physical dependence and pCREB for morphine, and locomotor sensitization and CART peptide over-expression for cocaine would be useful markers to predict the abuse potential of opioid analgesics and pychostimulant drugs in animals, respectively.

• Safety and Health at Work
• /
• 제12권2호
• /
• pp.249-254
• /
• 2021

Introduction: Workplace violence (WPV) is a major occupational and health hazard for nurses. It affects nurses' physical and psychological well-being and impacts health service delivery. We aimed to assess the prevalence and describe the consequences of WPV experienced by nurses working in an emergency department in Kenya. Methods: We conducted a descriptive cross-sectional study among emergency nurses at one of the largest tertiary hospitals in Kenya. We collected data using a structured questionnaire adapted from the 'WPV in the Health Sector, Country Case Studies Research Instruments' questionnaire. We described the prevalence and effects of WPV using frequencies and percentages. Results: Of the 82 participating nurses, 64.6% were female, 57.3% were married and 65.8% were college-educated (65.8%). Participants' mean age was 33.8 years (standard deviation: 6.8 years, range: 23-55). The overall lifetime prevalence of WPV was 81.7% (n = 67, 95% confidence interval [CI]: 71.6%-88.8%) and the 1-year prevalence was 73.2% (n = 63, 95% CI: 66.3-84.8%). The main WPV included verbal abuse, physical violence, and sexual harassment. Most incidents were perpetrated by patients and their relatives. No action was taken in 50% of the incidents, but 57.1% of physical violence incidents were reported to the hospital security and 28.6% to supervisors. Perpetrators of physical violence were verbally warned (42.9%) and reported to the hospital security (28.6%). Conclusion: Workplace violence is a significant problem affecting emergency nurses in Kenya. Hospitals should promote workplace safety with zero-tolerance to violence. Nurses should be sensitised on WPV to mitigate violence and supported when they experience WPV.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제9권2호
• /
• pp.138-147
• /
• 1998

전국의 산부인과, 소아과, 가정의학과 및 응급의학과 전문의 7055명을 대상으로 근친간 성학대를 당한 15세 이하 아동을 진료한 경험에 대하여 조사하여 다음과 같은 결과를 얻었다. 1) 조사에 응한 의사들(1205명)중 157명(13.0%)이 진료시작 후 지금까지 근친간 성학대를 당한 만 15세이하 아동 315명을 진료한 경험이 있다고 응답하였고 이중 8명은 조사시점 1개월 이내에, 71명은 조사시점 1달이내에 경험하였다. 성학대의 아동진료를 보고한 157명 의사중 111명(70%)은 산부인과 전문의였다. 2) 가해자중 형제가 58명(36.9%)으로서 가장 많았고, 계부 32명(20.4%), 친부 26명(16.6%) 순이었고 가해자의 연령 분포상 10대가 70명(44.6%)으로서 가장 많았으며, 다음은 40∼59세(33.7%)이었다. 성별로는 대부분(98.7%)이 남자였다. 3) 피해 아동의 나이는 2세부터 15세까지 다양하였는데, 평균연령은 $12.1{\pm}3.3$세였고, 15세가 41명(26.1%)으로서 가장 많았다. 성별로는 모두 여자였고, 대부분 정상아동이였다. 4) 근친간 아동성학대 사실을 알게 된 경위는 행동이 이상해서 추궁하여 알게 된 경우가 45명(28.7%), 아동이 직접 이야기해서 알게 된 경우가 40명(25.5%), 임신으로 인해 알게 된 경우는 18명(11.5%)이였다. 아동이 근친간 성학대를 당한 후 병원에 오기까지 소요된 시간은 1개월 이상이 97명(61.8%)으로서 가장 많았으며, 근친간 아동성학대는 잘 알려지지 않은 채 장기간 지속되는 경향이 있음을 시사하였다. 5) 신체적 피해 상황은 회음부 손상이 93명(59.2%), 처녀막 파열이 90명(57.3%), 임신이 68명(43.3%)으로서, 임신 때문에 근친간 성학대가 발견되고 의사를 찾게 되었음이 두드러진 특성으로 보였다. 상기 결과는 상당수의 의사들이 근친간 성학대를 당한 피해 아동을 진료하고 있고 근친간 아동성학대는 사회적 문제일뿐 아니라 의학적으로도 중요한 문제이며 근친간 아동성학대의 예방과 치료를 위해서는 의사들의 적극적인 관심과 노력이 필요함을 시사한다. 또한 근친간 아동성학대는 가해자가 친족이라는 정의상의 차이점 외에 빈도와 의뢰이유, 발견방법, 신체적 후유증 및 학대의 원인등에서 가정외 아동성폭력과 매우 다른 양상을 보였음은 앞으로 아동성학대 연구에서 이들을 구분하여 연구할 필요성을 시사해준다.