• 제목/요약/키워드: perusal

검색결과 6건 처리시간 0.022초

Roles of Galectin-7 in Cancer

  • Kaur, Manpreet;Kaur, Tarnjeet;Kamboj, Sukhdev Singh;Singh, Jatinder
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.455-461
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    • 2016
  • Galectins are ${\beta}$-galactoside binding lectins that contain one or more carbohydrate recognition domains. As a consequence of sugar-binding properties, galectins exhibit a variety of interactions with glycoproteins, thus playing important roles in various pathological processes. A number of studies have shown roles of galectins in cancer. Galectin-7 is a prototype member of the galectin family implicated in epithelial stratification and cell migration. It can act as a potent dual regulator in different types of cancer. Galectin-7 may contribute either to neoplastic transformation and tumour progression through regulation of cell growth, cell cycle, angiogenesis, apoptosis and cell migration or may have a protective effect in cancer depending on the tissue type. A perusal of the literature indicates particular roles of galectin-7 in carcinomas and melanomas, while contributions await greater exploration in other types of cancers including sarcomas and leukemia. This review collectively summarizes available literature on expression and roles of galectin-7 in different cancers.

AHP 방법에 의한 기록연구사의 직무분석 (Job Analysis of Records Managers based on the AHP Method)

  • 이성태
    • 한국기록관리학회지
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    • 제9권2호
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    • pp.133-158
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    • 2009
  • 본 연구는 기록연구사의 정체성이 명확하지 못하고 기록연구사의 역할이 정확히 인식되지 못하고 있다는 문제의식에서 출발하였다. 그래서 기록연구사가 어떤 직무를 하고 있고 어떤 직무를 수행해야 하는지를 파악하고자 하였다. 이에 직무분석방법을 이용하여 기록연구사의 직무정보를 파악하였으며 AHP 분석을 이용하여 기록연구사의 핵심직무를 파악하였다. 그 결과 기록관리정책수립, 교육, 생산제어, 기준관리, 수집, 이관, 정리/기술, 평가, 폐기, 서고관리, 공개, 열람서비스, 기록관리시스템 영역이 핵심직무로 분석되었다. 그리하여 기록연구사의 정체성과 역할을 제시하고 직무의 우선순위를 제시할 수 있었다.

지식정보의 형태적 진화와 도서관 서가의 변천에 관한 연구 - 20세기이전의 서양도서관사를 중심으로 - (A Study on the Changes of the Library's Bookshelves by the Morphological Evolution of Knowledge-Information - Focus on the History of Western Libraries before the 20th Century -)

  • 황미영
    • 한국실내디자인학회논문집
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    • 제19권4호
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    • pp.90-98
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    • 2010
  • This study intends to understand the change of the library's bookshelves shape, composition and arrangement based on the social-culture in each period. For this purpose, this study analyzes the morphological shift of the library's bookshelves and knowledge information focused on the history of western libraries from the ancient libraries to the modern public libraries before the 20th century. And the results are follows. 1) We can make sure that the changes of the library's bookshelves are based on the environmental factors like social cultural political factors and also understand that the knowledge information are developed based on the function which is decided by the needs of the times and the serious necessities of users. With this reason, the morphology and the function of the library's bookshelves have been changed. 2) The characters and meanings of the library's bookshelves are changed with the times from movable type to fixed type, from closing type to opening type, from privileged use to public use, from religious contents to general scientific contents. 3) The morphology of the library's bookshelves are shifted from cylindrical box to Chest type Press type and Lectern system, Stall system, Wall system and advanced to Mixed(Stall+Wall) system. 4) The construction and arrangement methods of the library's bookshelves are determined by the convenience and efficiency of the installation for the perusal environments as well as the regarding to the social-cultural factors. The arrangement criteria are determined by the security topics in the earlier stage, after that determined by the lightening topics and nowadays the access topics to the information. These analysis results are very useful to research the technology of the library's bookshelves to be changed continuously and also to forecast the morphology of the library's bookshelves can be planned in the spaces of the future libraries.

국학고전자료의 디지털화를 위한 모범적인 방안 연구 (Study on Model Case of Ideal Digitization of Korean Ancient Books)

  • 이희재
    • 정보관리학회지
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    • 제22권1호
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    • pp.105-123
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    • 2005
  • 이 연구는 보존 기록 자료로서의 우리의 고전 장서를 보다 안전하게 보호하고 연구자나 이용자들에게는 시공을 초월한 열람이 가능토록 하기 위한 디지털 도서관으로서의 방법을 모색하는 데 목적이 있다. 즉, 우선 동양 전래의 사부 분류법과 현대적인 주제 분류, 그리고 색인어 등을 통해 다양한 접근점을 제공하고, 둘째, MARC나 XML 등을 활용한 DL시스템을 구축하되, 서지적 기술요소를 최대한 확대시키며. 셋째, 쉬운 해제와 색인어로 이용자의 이해를 극대화하고, 마지막으로 원본의 손상을 막기 위해 원문 DB를 구축하여 열람용으로 사용한다. 이는 향후 국내외 한국 고전 관련기관과 협력, 공유할 수 있는 네트워크 체제를 통해 국제적 서지통정으로 발전될 수 있을 것이다.

OpenAPI를 이용한 실시간 자치도서관 도서검색 서비스구현 (Implementation of Real-time Book Search Service of Library using OpenAPI)

  • 임대현;박진태;이혜림;정재필;문일영
    • 한국항행학회논문지
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    • 제13권5호
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    • pp.793-798
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    • 2009
  • 본 논문에서는 OpenAPI를 이용해 실시간 자치도서관 도서통합검색 서비스에 대해 구현하였다. 2000년도부터 독서 장려정책으로 각 시,도등 자치지역마다 지역민들을 위한 지역도서관이 지어지기 시작했다. 이를 통해 방대한량의 도서를 확보하고 각 자치도서관은 회원제를 통해 대여 및 열람을 서비스하고 있다. 일반적으로 각 자치도서관에 방문하여 대여/반납과 열람하고, 각 도서관별 홈페이지를 운영하여 도서현황을 검색하고, 예약서비스를 하고 있다. 하지만 방대한 도서를 검색하고 이용하기란 쉽지 않은 실정이다. 따라서 현재 각 도서관에서 구축되어있는 모든 시스템의 구성 그대로 활용하면서 각 도서관별 데이터베이스의 효율적 통합과 검색을 위한 방안으로 TCP/IP방식의 네트워크와 각 도서관의 Database를 연결하기 위한 어플리케이션, OpenAPI 이용한 실시간 Database접근을 통해 도서검색을 서비스하는 방안을 제시하고자 한다.

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항공(航空) 자유화(自由化)와 '단일(單一)' 유럽항공시장(航空市場) 접근(接近);유럽사법재판소(司法裁判所)의 미(美) ${\cdot}$ 독(獨) 항공운수협정(航空運輸協定)상 '국적요건(國籍要件)' 조항(條項)의 공동체법(共同體法)상 '내국민대우(內國民待遇)' 규정 위반(違反) 관련 '집행위원회(執行委員會) 대(對) 독일연방(獨逸聯邦)' 사건 판결(判決)(2002)의 문제점을 중심으로 ('Open Skies' Agreements and Access to the 'Single' European Sky;Legal and Economic Problems with the European Court of Justice's Judgment in 'Commission v. Germany'(2002) Striking Down the 'Nationality Clause' in the U.S.-German Agreement)

  • 박현진
    • 한국항공운항학회지
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    • 제15권1호
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    • pp.38-53
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    • 2007
  • In a seminal judgment of November 2002 (Case C-476/98) relating to the compatibility with Community laws of the 'nationality clause' in the 1996 amending protocol to the 1955 U.S.-German Air Services Agreement, the European Court of Justice(ECJ) decided that the provision constituted a measure of an intrinsically discriminatory nature and was thus contrary to the principle of national treatment established under Art. 52 of the EC Treaty. The Court, rejecting bluntly the German government' submissions relying on public policy grounds(Art. 56, EC Treaty), seemed content to declare and rule that the protocol provision requiring a contracting state party to ensure substantial ownership and effective control by its nationals of its designated airlines had violated the requirement of national treatment reserved for other Community Members under the salient Treaty provision. The German counterclaims against the Commission, although tantalizing not only from the perusal of the judgment but from the perspective of international air law, were nonetheless invariably correct and to the point. For such a clause has been justified to defend the 'fundamental interests of society from a serious threat' that may result from granting operating licenses or necessary technical authorizations to an airline company of a third country. Indeed, the nationality clause has been inserted in most of the liberal bilaterals to allow the parties to enforce their own national laws and regulations governing aviation safety and security. Such a clause is not targeted as a device for discriminating against the nationals of any third State. It simply acts as the minimum legal safeguards against aviation risk empowering a party to take legal control of the designated airlines. Unfortunately, the German call for the review of such a foremost objective and rationale underlying the nationality clause landed on the deaf ears of the Court which appeared quite happy not to take stock of the potential implications and consequences in its absence and of the legality under international law of the 'national treatment' requirement of Community laws. Again, while US law limits foreign shareholders to 24.9% of its airlines, the European Community limits non-EC ownership to 49%, precluding any ownership and effective control by foreign nationals of EC airlines, let alone any foreign takeover and merger. Given this, it appears inconsistent and unreasonable for the EC to demand, $vis-{\grave{a}}-vis$ a non-EC third State, national treatment for all of its Member States. The ECJ's decision was also wrongly premised on the precedence of Community laws over international law, and in particular, international air law. It simply is another form of asserting and enforcing de facto extraterritorial application of Community laws to a non-EC third country. Again, the ruling runs counter to an established rule of international law that a treaty does not, as a matter of principle, create either obligations or rights for a third State. Aside from the legal problems, the 'national treatment' may not be economically justified either, in light of the free-rider problem and resulting externalities or inefficiency. On the strength of international law and economics, therefore, airlines of Community Members other than the designated German and U.S. air carriers are neither eligible for traffic rights, nor entitled to operate between or 'free-ride' on the U.S. and German points. All in all and in all fairness, the European Court's ruling was nothing short of an outright condemnation of established rules and principles of international law and international air law. Nor is the national treatment requirement justified by the economic logic of deregulation or liberalization of aviation markets. Nor has the requirement much to do with fair competition and increased efficiency.

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