• Child Health Nursing Research
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• 제10권1호
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• pp.89-97
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• 2004

Purpose: Adolescence is viewed as a critical period in the formation of health behavior and many health behaviors developed during this era persist into adulthood. Social-cognitive theory, self-efficacy as a central construct, has been used to predict and intervene the health behavioral patterns in adolescent. Previous research demonstrated that the attachment in childhood and self-esteem as psychosocial factors are predictors of the health efficacy in adolescent and it is viewed as solely an antecedent for the lifelong health behavior. Method: To investigate the path pattern of attachment in childhood, self-esteem and health efficacy in adolescents, 381 adolescents in high school from two urban cities in Korea were recruited for cross-sectional sample. Attachment in childhood was measured using Mother-Father-Peer Scale. Self esteem was measured with Hare self esteem. Perceived self efficacy in Health was measured by the School Health Efficacy Questionnaire. The path analysis revealed a significant relationship between attachment in childhood and self-esteem, self-esteem and health efficacy in adolescents. Self esteem was the strongest contributing factor for health efficacy in adolescent. The results suggest that attachment in childhood may aid in formulating positive self -esteem in adolescents and self-esteem played a major role in predicting health efficacy in adolescents. Conclusion: Therefore, self-esteem enrichment should be incorporated with adolescent health promotion and certainly should be a component in any health education program in school health program and interventions. These results have implications of psychosocial and family related factors on health promotion and health education for the health care provider with regard to primary and secondary prevention in adolescent population.

• 의학교육논단
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• 제16권2호
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• pp.99-107
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• 2014

The purpose of this study was to establish a better operation plan for medical school student internship by gaining a deeper understanding of the student internship process. Toward this end, an investigation was carried out using in-depth interviews of students with experience as student internship at Catholic University of Daegu School of Medicine. Students who participated in the student internship program at Catholic University of Daegu School of Medicine took part in the clinic twice every two-week period for a total of four weeks as a member of the care team. The students performed several activities during their internships, including for example history taking, physical examinations, keeping medical records, simulation of writing prescriptions, clinical skills, patient education, night work, and rounds with the attending professor. In this study were analyzed the contents of a student internship, the difference in clerkship, the competence of the faculty, student participation attitudes and the overall effect of the internship on the students. It was found that the in-depth contents, passion of members including professors and students, especially the role of the professor, was more important component than the contents of the internship program or clinical training. The student-intern system was revealed to have the following positive characteristics: 1) education deeper than clerkship was performed through one-on-one faculty-student interaction, and 2) students' experience was broadened.

• 멤브레인
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• 제18권1호
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• pp.53-64
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• 2008

벤토나이트 현탁액에 의한 폴리에틸렌 정밀여과 모세관 막의 오염특성에 대하여 검토하였다. 막오염의 윈인은 막표면 위에서 생성되는 케익층의 성장과 입자들이 세공을 막는 표준 및 완전세공막힘 때문이었으며, 막오염은 이들 세 가지 오염형태가 동시에 발생하지만 케익여과오염에 의해 크게 지배를 받는다. 운전압력 $1.0kg/cm^2$에서 총 막오염에 대한 성분오염의 비율은 표준세공막힘 3.36%, 완전세공막힘 3.18% 그리고 케익여과오염 93.46%이었다. 현탁액의 농도가 1000 ppm인 경우에는 완전세공막힘 1.71%, 표준세공막힘 1.90% 그리고 케익여과오염이 96.39%이었으며, 운전초기에 총 오염의 96.14%가 발생했다. 총 오염에 대한 케익여과의 영향은 세공이 $0.34{\mu}m$막에서 컸다. 순환흐름속도의 증가로 인해 성분오염은 약 10.20% 감소하였고, 총 오염에 대한 세공막힘의 비율은 높았다.

• 한국항공우주학회지
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• 제41권12호
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• pp.994-1001
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• 2013

헬기의 개발 과정은 설계, 제작 및 시험평가로 구분될 수 있으며, 시험평가는 구성품 시험, Rig 시험, 체계 지상시험 및 비행시험의 순서로 단계적으로 수행된다. 지상시험이 종료되고 최초 비행에 앞서, 비행 안전성을 담보하기 위해 미군사규격은 50시간 비행전 수락시험을 요구하고 있다. 비행전 수락시험은 헬기를 지상결박하여 가혹한 하중을 부과하는 시험으로서, 이의 수행을 위해서는 헬기 시제기와 유사한 별도의 지상 시험 시제기가 필요하며, 많은 비용과 기간이 소요되는 시험이다. KUH의 경우 국내 개발 환경을 고려하여 미군사규격의 요구도를 변형 후 수행하였으며, 본 논문은 KUH 비행전 수락시험의 절차 및 결과를 통하여 헬기 개발 환경에 따른 적절한 비행전 수락시험 수행 방안을 제시하고자 한다.

• 대한약침학회지
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• 제20권3호
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• pp.158-172
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• 2017

Nigella sativa (N. sativa, family Ranunculaceae) is a medicinal plant that has been widely used for centuries throughout the world as a natural remedy. A wide range of chemical compounds found in N. sativa expresses its vast therapeutic effects. Thymoquinone (TQ) is the main component (up to 50%) in the essential oil of N. sativa. Also, pinene (up to 15%), p-cymene (40%), thymohydroquinone (THQ), thymol (THY), and dithymoquinone (DTQ) are other pharmacologically active compounds of its oil. Other terpenoid compounds, such as carvacrol, carvone, 4-terpineol, limonenes, and citronellol, are also found in small quantities in its oil. The main pharmacological characteristics of this plant are immune system stimulatory, anti-inflammatory, hypotensive, hepatoprotective, antioxidant, anti-cancer, hypoglycemic, anti-tussive, milk production, uricosuric, choleretic, anti-fertility, and spasmolytic properties. In this regard, we have searched the scientific databases PubMed, Web of Science, and Google Scholar with keywords of N. sativa, anti-cancer, apoptotic effect, antitumor, antioxidant, and malignancy over the period from 2000 to 2017. The effectiveness of N. sativa against cancer in the blood system, kidneys, lungs, prostate, liver, and breast and on many malignant cell lines has been shown in many studies, but the molecular mechanisms behind that anti-cancer role are still not clearly understood. From among the many effects of N. sativa, including its anti-proliferative effect, cell cycle arrest, apoptosis induction, ROS generation, anti-metastasis/anti-angiogenesis effects, Akt pathway control, modulation of multiple molecular targets, including p53, p73, STAT-3, PTEN, and $PPAR-{\gamma}$, and activation of caspases, the main suggestive anti-cancer mechanisms of N. sativa are its free radical scavenger activity and the preservation of various anti-oxidant enzyme activities, such as glutathione peroxidase, catalase, and glutathione-S-transferase. In this review, we highlight the molecular mechanisms of apoptosis and the anti-cancer effects of N. sativa, with a focus on its molecular targets in apoptosis pathways.

• 한국수산과학회지
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• 제27권2호
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• pp.200-214
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• 1994

진해만의 저서동물 군집생태 연구의 일환으로 저서환경의 특성을 구명하기 위하여, 1987년 6월부터 1990년 5월까지 12개 정점에서 표층 및 저층수의 수온, 염분, 용존산소와 퇴적물의 입도조성 및 유기물량을 조사하였다. 진해만의 저서환경은 내만으로 들어 갈수록 퇴적물 입도의 세립화, 높은 유기물함량, 여름철 성층의 발달로 인한 저층 빈산소 수괴의 형성 등이 특징적으로 나타났다. 저층의 빈산소수괴는 5월부터 내만에서 형성되기 시작하여, 여름철로 접어들면서 점차 외해역으로 확산되어 9월에 최고에 달하였으며, 진해만 전 해역의 절반이상이 빈산소 영향을 받고 있는 것으로 나타났다. 이러한 저층의 빈산소 환경은 가을철로 접어들면서 성층의 점진적 소멸과 함께 회복된다. 저층수의 수온, 염분 및 용존 산소량과 퇴적물의 입도 및 유기물 함량의 5개 환경요인에 대하여 주성분 분석을 실시한 결과 4개 해역으로 나눌 수 있었으며, 이러한 공간 분포는 전반적으로 퇴적물의 유기물함량과 가장 높은 상관관계를 가지는 것으로 나타났다.

• Preventive Nutrition and Food Science
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• 제8권4호
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• pp.390-394
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• 2003

In the post-genome period, the technique for identifying gene expression has been progressed to high throughput screening. In the field of molecular nutrition, the use of screening techniques to clarify molecular function of specific nutrients would be very advantageous. In this study, we have evaluated Zn-regulated gene expression in Zn-deficient, homocystein-treated EA.hy926 cells, using cDNA microarray, which can be used to screen the expression of many genes simultaneously. The information obtained can be used for preliminary assessment of molecular and signaling events modulated by Zn under pro-atherogenic conditions. EA.hy926 cells derived from human umbilical vein endothelial cells were cultured in Zn-adequate (control, 15 $\mu$M Zn) or Zn-deficient (experimental, 0 $\mu$M Zn) Dulbecco's MEM media under high homocysteine level (100 $\mu$M) for 3 days of post-confluency. Cells were harvested and RNA was extracted. Total RNA was reverse-transcribed and the synthesized cDNA was labeled with Cy3 or Cy5. Fluorescent labeled cDNA probe was applied to microarray slides for hybridization, and the slide was then scanned using a fluorescence scanner. The expression of seven genes was found to be significantly decreased, and one significantly increased, in response to treatment of EA.hy926 cells with Zn-deficient medium, compared with Zn-supplemented medium. The upregulated genes were oncogenes and tumor suppressor genes, cell cycle-related genes and transporter genes. The down-regulated gene was RelB, a component of the NF-kappaB complex of transcription factors. The results of this study imply the effectiveness of cDNA microarray for expression profiling of a singly nutrient deficiency, namely Zn. Furthur study, using tailored-cDNA array and vascular endothelial cell lines, would be beneficial to clarify the molecular function of Zn in atherosclerosis, more in detail.

• 한국환경과학회지
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• 제15권10호
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• pp.919-928
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• 2006

The present study applied an atmospheric flow field model in Gwangyang-Bay which can predict local sea/land breezes formed in a complex terrain lot the development of a model that can predict short term concentration of air pollution. Estimated values from the conduct of the atmospheric flow field were used to evaluate and compare with observation data of the meteorological stations in Yeosu and the Yeosu airport, and the effect of micrometeorology of surround region by the coastal area reclamation was predicted by using the estimated values, Simulation results, a nighttime is appeared plainly land breezes of the Gwangyang-bay direction according to a mountain wind that formed in the Mt. of Baekwooun, Mt. of Youngchui. Land winds is formed clockwise circulation in the north, clockwise reverse direction in the south with Gangyang-bay as the center. Compared with model and observation value, Temperature is tend to appeared some highly simulation value in the night, observation value in the daytime in two sites all, but it is veil accorded generally, the pattern of one period can know very the similarity. And also, wind speed and wind direction is some appeared the error of observation value and calculation results in crossing time of the land wind and sea land, it can see that reproducibility is generally good, is very appeared the change land wind in the nighttime, the change of sea wind in the daytime. And also, according to change of the utilization coefficient of soil before and after development with Gwangyang-Bay area as the center. Temperature after development was high $0.55\sim0.67^{\circ}C$ in the 14 hoots, also was tend to appear lowly $0.10\sim0.22^{\circ}C$ in the 02 hours, the change of u, v component is comparatively tend to reduced sea wind and land wind, it is affected ascending air current and frictional power of the earth surface according to inequality heating of the generation of earth surface.

• 대한족부족관절학회지
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• 제23권4호
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• pp.183-188
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• 2019

Purpose: Bone contusion is usually treated with conservative therapy for 3 months. Bone contusion around knee and hip joints has been extensively reported on, but there are scant reports on this condition in foot and ankle joints. This study evaluated the nature, characteristics and location of bone contusion around foot and ankle joints to enlighten clinicians on how to better treat this disease entity. Materials and Methods: We classified bone contusion of the 76 patients into three types (102 sites; 47 ankle sprains, 18 traffic accidents, 11 falls) according to the Costa-Paz system with employing magnetic resonance imaging (MRI), and the study then analyzed the common sites and areas of occurrence according to the mechanism of injury and duration of pain after first conducting conservative therapy. Results: Of the 76 patients (102 sites) on the MRI, 43 case (42.2%) for talus, 19 cases for distal tibia, and 12 cases for calcaneus were involved. The classification, according to the Costa-Paz system, was Type I, 51 cases; Type II, 32 cases; and Type III, 19 cases. The duration of pain after conservative treatment was 12.15±2.17 weeks for Type I, 14.5±2.15 weeks for Type II, and 21.0±3.8 weeks for Type III. Conclusion: The most common location of post-traumatic bone contusion around both the foot and ankle is the talus, distal tibia, and calcaneus. The most common type of injury noted on MRI is a diffuse signal with change of the medullary component (Type I), In cases of bone contusion extending to a subjacent articular surface or disruption or depression of the normal contour of the cortical surface (Types II, III), the patients' pain appears to last longer. Thus, it is necessary to consider a longer period of conservative treatment in cases of Types II and III bone contusion because the patients' pain may last longer than 3 months.

• 한국자동차공학회논문집
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• 제24권1호
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• pp.33-38
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• 2016

The turbocharger is an essential component to realize the engine down-sizing. The moment of inertia of turbocharger rotor is an important parameter with respect to acceleration performance of the vehicle. It can be calculated from the CAD software based the geometry data and the material properties. But the accurate value of the inertia of turbocharger rotor must be measured through the experimental method. In this study, the measurement of moment of inertia of turbocharger rotor for 2.0 L spark-ignition engine was carried out. First, an experimental equipment using a trifilar method was designed and fabricated. Some optical devices, that is, photo sensor, counter, convex lens, etc, were used to increase the accuracy of the measurement. Second, error sensitivity for the equipment was analyzed. The error of period time and the radius can give big affects to the accuracy of the moment of inertia. When the amount of error of these two were each 1.0 %, maximum error of the moment of inertia was under 3.0 %. Third, the calibration for the equipment was performed using a calibration rotor which has similar shape to turbine rotor but simple. Calculated value from CAD software and measured one for the calibration rotor were compared. The total error of the equipment and the measurement is about 1.3 %. This result shows that the equipment can give the good result with resonable accuracy. Finally the moment of inertia of the turbine rotor and compressor wheel were measured. The coefficient of variations, the ratio of standard deviation to mean value, were reasonably small at 0.57 % and 0.73 % respectively. Therefore this equipment is suitable for the measurement of the moment of inertia of the turbine rotor and compressor wheel.