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Comparison of Gangji-hwan-1, 2, 3, 4 and Combination of Gangji-hwan-1 and Gamisoche-hwan in the Reducing Effects of Body Weight in a High Fat Diet-Fed Obese Mice (고지방식이 비만마우스 모델에서 파키스탄산 및 중국산 마황으로 조성된 강지환(降脂丸)-1, 2, 3, 4와 강지환(降脂丸)-1합가미소체환(合加味消滯丸)의 체중감량효과 비교)

  • Yoo, Jae Sang;Ku, Ja Ryong;Yoon, Ki Hyeon;Jo, Ju Heum;Jang, Du Hyon;Jung, Yang Sam;Kim, Jong Hoon;Kim, Byeong Chul;Seok, Hoa Jun;Yoon, Michung;Roh, Jong Seong;Shin, Soon Shik
    • Journal of Korean Medicine for Obesity Research
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    • v.15 no.1
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    • pp.9-23
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    • 2015
  • Objectives: This study was investigated the improvement effects of Pakistani Ephedra herba-containing Gangji-hwan-1, 2, 3 (Di-fatty; DF-1, 2, 3), Chinese Ephedra herba-containing Gangjihwan-4 (DF-4) and combination of DF-1 and Gamisoche-hwan (GSH) on obesity in a high fat diet-fed obese mouse model. Methods: Eight-week-old C57BL/6N mice were divided into seven groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and DF-1, 2, 3, 4, and DF-1+GSH groups given a high fat diet with DF-1, 2, 3, 4 (40, 80, 160, 80 mg/kg), and DF-1+ GSH (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, feeding efficiency ratio (FER), blood lipid markers, liver histology, and fat weight and histology were examined. Results: Body weight gain was significantly decreased in DF and DF-1+GSH groups compared with control. The extent of decreases was eminent in DF-1+GSH group. FER and circulating concentration of leptin were decreased in DF and DF-1+GSH groups compared with control. Circulating concentrations of triglyceride, glucose and insulin were decreased in DF and DF-1+GSH groups compared with control. The size of adipocytes were decreased by DF and DF-1+GSH groups compared with control, whereas the adipocyte number per unit area was increased by them, suggesting that DF and DF-1+GSH groups decreased the number of large adipocytes. Conclusions: In conclusion, these results suggest that DF and DF-1+GSH groups decrease FER, plasma leptin concentration, blood anti-obesity biomarkers and fat mass, improves body weight gain. In addition, these effects were more effective in DF-1+GSH combination group than in DF-1, 2, 3, 4 groups.

Fabrication process of embedded passive components in MCM-D (MCM-D 기판 내장형 수동소자 제조공정)

  • 주철원;이영민;이상복;현석봉;박성수;송민규
    • Journal of the Microelectronics and Packaging Society
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    • v.6 no.4
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    • pp.1-7
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    • 1999
  • We developed Fabrication process of embedded passive components in MCM-D substrate. The proposed MCM-D substrate is based on Cu/photosensitive BCB multilayer. The substrate used is Si wafer and Ti/cu metallization is used to form the interconnect layer. Interconnect layers are formed with 1000$\AA$ Ti/3000$\AA$ Cu by sputtering method and 3$\mu\textrm{m}$ Cu by electrical plating method. In order to form the vias in photosensitive BCB layer, the process of BCB and plasma etch using $C_2F_6$ gas were evaluated. The MCM-D substrate is composed of 5 dielectric layers and 4 interconnect layers. Embedded resistors are made with NiCr and implemented on the $2^{nd}$ dielectric layer. The sheet resistance of NiCr is controlled to be about 21 $\Omega$/sq at the thickness of 600$\AA$. The multi-turn sprial inductors are designed in coplanar fashion on the $4^{th}$ interconnect layer with an underpass from the center to outside using the lower $3^{rd}$ interconnect layer. Capacitors are designed and realized between $1^{st}$ interconnect layer and $2^{nd}$ interconnect layer. An important issue in capacitor is the accurate determination of the dielectric thickness. We use the 900$\AA$ thickness of PECVD silicon nitride film as dielectric. Capacitance per unit area is about 88nF/$\textrm {cm}^2$at the thickness of 900$\AA$. The advantage of this integration process is the compatibility with the conventional semiconductor process due to low temperature PECVD silicon nitride process and thermal evaporation NiCr process.

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Analysis of Energy Consumption Pattern and Greenhouse Gas Emission in the Academic Facility (대학에서의 에너지 소비패턴 및 온실가스 배출현황 분석)

  • Kim, Jin-Sik;Lee, Kyoung-Bin;Lee, Im-Hack;Kim, Shin-Do
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.9
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    • pp.604-612
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    • 2012
  • Self-management plan for GHG (Greenhouse Gas) reduction should be prepared in academic facilities, which occupy a large amount of energy consumption. In this study, a university was chosen as one of the major academic facilities and its energy consuming pattern and GHG emission were analyzed. The results have shown that annual $CO_2$ emission from university buildings was 10,452 ton-$CO_2$ (0.65 ton-$CO_2/m^2$), and dependent upon 78.0% electricity, 20.5% LNG and 1.5% oil, respectively as energy sources. According to more detail analysis by usage of energy consumption, appliances occupies 36.7% followed by gas heating (18.9%), lighting (18.6%), heating with electricity (12.5%), cooling with electricity (10.2%), transportation (1.5%), gas cooling (1.2%) and cooking (0.4%). Furthermore, annual $CO_2$ emissions per unit area and a student by electricity usage were evaluated to 51.30 kg-$CO_2/m^2$ and 981.86 kg-$CO_2$/capita, respectively and those by LNG usage were 14.61 kg-$CO_2/m^2$ and 241.01 kg-$CO_2$/capita.

THE EFFECT OF DIFFERENT CURING MODES ON COMPOSITE RESIN/DENTIN BOND STRENGTH IN CLASS ICAVITIES (1급 와동에서 상아질과 복합레진의 결합강도에 대한 중합방법의 효과)

  • Baek, Shin-Young;Cho, Young-Gon;Song, Byeong-Choon
    • Restorative Dentistry and Endodontics
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    • v.33 no.5
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    • pp.428-434
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    • 2008
  • The purpose of this study was to compare the microtensile bond strength in Class I cavities associated with different light curing modes of same light energy density. Occlusal enamel was removed to expose a flat dentin surface and twenty box-shaped Class I cavities were prepared in dentin. Single Bond (3M Dental product) was applied and Z 250 was inserted using bulk technique. The composite was light-cured using one of four techniques, pulse delay (PD group), soft-start (SS group), pulse cure (PC group) and standard continuous cure (CC group). The light-curing unit capable of adjusting time and intensity (VIP, Bisco Dental product) was selected and the light energy density for all curing modes was fixed at $16J/cm^2$. After storage for 24 hours, specimens were sectioned into beams with a rectangular cross-sectional area of approximately $1mm^2$ Microtensile bond strength $({\mu}TBS)$ test was per- formed using a univel·sal testing machine (EZ Test, Shimadzu Co.). The results were analyzed using oneway ANOVA and Tukey's test at significance level 0.05. The ${\mu}TBS$ of PD group and SS group was higher than that of PC group and CC group. Within the limitations of this in vitro study, modification of curing modes such as pulse delay and soft start polymerization can improve resin/dentin bond strength in Class I cavities by controlling polymerization velocity of composite resin.

Constructing of Humidity Automatic Regulation Environment to Build Effective Mushroom Growing Environment (버섯의 효과적인 생육환경 구축을 위한 자동 습도조절 환경 연구)

  • Xu, Chen-Lin;Lee, Hyun-Chang;Kang, Sun-kyung;Shin, Seong-Yoon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.11
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    • pp.2597-2602
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    • 2015
  • With the development of economy and improving of people's living standards, people dietary needs will be achieved from subsistence to high nutrition and from high nutrition to healthy transformation. Mushroom as a kind of highly nutritious, low fat, rich vitamin food has a great interest among the people. This makes the mushroom into a new sunrise industry and it gradually from pure manual cultivation develops toward the fully automatic factory. In the process of mushroom factory production, regulation of environmental factors directly affects the yield and quality of mushroom. In related to the methods of mushroom cultivation, the recent technologies apply the new technology such as sensors and IT convergence services. And then cultivating mushroom is managed effectively. This paper in order to solve the above problems and construct an effective mushroom growth environment using technology such as humidity sensor construct an environment that can automatically adjust the humidity. This environment has important significance to improve the level of automation mushroom production, increase yield per unit area and quality of mushroom, increase economic efficiency of mushroom production, and enhance the competitiveness of mushroom production.

Relationship between Leaf Chlorophyll Reading Value and Soil N-supplying Capability for Tomato in Green House (시설재배 토마토 잎의 엽록소 측정치와 토양 질소공급능력의 상호관계)

  • Hong, Soon-Dal;Kim, Ki-In;Park, Hyo-Taek;Kang, Seong-Soo
    • Korean Journal of Soil Science and Fertilizer
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    • v.34 no.2
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    • pp.85-91
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    • 2001
  • To find diagnosing method of nitrogen status in tomato plant for determining optimum application rate of side dress, chlorophyll reading values were measured by portable chlorophyll meter(SPAD 502, Minolta), and compared with nitrogen supplying capability of soils. Regression between dry weight, amount of nitrogen uptake, and chlorophyll reading at stalk positions of tomato grown on the condition of no fertilization were evaluated For 6 green house soils with different nitrate concentrations ranged from $55mg\;kg^{-1}$ to $306mg\;kg^{-1}$. The chlorophyll reading of tomato leave was significantly correlated with amount of nitrogen per unit area of leave suggesting that chlorophyll content is useful for nitrogen diagnosis of tomato plant. The chlorophyll reading showed peak at the 15th leaf of stalk position on the 45th days after transplanting and this suggested that below or near the 15th leaf and before or near the 45th days after transplanting is the critical stalk position and time for diagnosing nitrogen status of tomato by chlorophyll test. The chlorophyll reading at the 14th leaf on the 40th days after transplanting was significantly correlated with soil nitrate status, dry weight and amount of nitrogen uptake by tomato grown with no fertilization. From the above correlation, the chlorophyll reading value of 57.1 at the 14th leaf of tomato was estimated as the critical level for maximum dry weight and amount of nitrogen uptake by tomato grown with no fertilization. Consequently, chlorophyll reading of tomato leaves measured by portable chlorophyll meter was thought to be available as a rapid plant test for predicting the nitrogen supplying capability of green house soils.

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Comparison of Farm Based Fertilizer Usage in 1992 and 1999 (1992년과 1999년의 농가 비료이용 실태 변화 비교)

  • Kim, Seok-Cheol;Park, Yang-Ho;Lee, Youn;Lee, Ju-Young;Kim, Chung-Su;Kim, Pil-Joo
    • Korean Journal of Soil Science and Fertilizer
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    • v.36 no.5
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    • pp.344-355
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    • 2003
  • Korea is one of those countries that have very high usage rates of chemical fertilizers per unit area of cropland. To reduce the fertilizer application rate, a variety of agricultural polices has been introduced since the 1990s. In this study, fertilizer usage was surveyed on the farm base throughout the country in 1999, and the data were compared with those of 1992. Organic fertilizer application rates were decreased in most cereal crops with time pass, but maintained similar levels in vegetables grown in plastic-film houses and in upland soils. Chemical fertilizer application rates were decreased in most of the cereal crops and vegetables surveyed; however, this reduction was concentrated in phosphate and potassium usage, but not in nitrogen. In spite of this decrease, the fertilizer application levels to most crops were maintained at levels much higher than recommended. In the nutrient balance, which was calculated from the difference between input (chemical and organic fertilizers) and output (agricultural products), the nitrogen nutrient surplus did not decrease; however, phosphate and potassium decreased by 21% and 13%, respectively, in 1999 compared with 1992. To reduce fertilizer utilization and to conserve environment, further reduction of fertilizer application is essential.

A Study on Dose Distribution around Fletcher-Suit Colpostat Containing Cs-137 Source by a Computer (컴퓨터 의한 Fletcher-Suit Colpostat 주변의 Cs-137의 선량분포에 관한 연구)

  • Kang Wee-Saing
    • Radiation Oncology Journal
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    • v.7 no.2
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    • pp.305-311
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    • 1989
  • Fletcher-Suit colpostat has an internal structure to reduce dose to bladder and rectum. Some programs were developed to calculate dose at any point in water in three dimension around the colpostat containing Cs-137 tube, to find the shielding effect to dose by the internal structure, and to draw isodose curves and iso-shielding effect curves. Computer was an IBM compatible AT with EGA card and language was MS-Basic V6.0, Material, shape and geometry of the strucure, tube and colpostat were considered in algorithm for calculation of dose. Dose rates per unit mg. Ra. eq. in water calculated by a program were stored in auxiliary memory devices and retrieved in another programs. Isodose curves on medial side shrinked. Dose distribution was not symmetric about a transverse axis bisecting the colpostat. Reduction of dose was more excessive on top side than on bottom. Iso-shielding effect curve showed that the shielding effect was higher on top side than on bottom, and that there was shielding effect over almost all area of medial side. Such results were related to both shifted position of tube in the colpostat and asymmetric distribution of active source in the tube. Maximum of shielding effect was $49\%$ on top side and $44\%$ on bottom side. The direction of iso-shielding effect curve was generally radial from the center of active source. In treatment planning using Fletcher-Suit colpostat, the internal structure should be considered to find precise doses to bladder and rectum, etc.

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Chemical Characteristics of soils in Cheju Island -II. Variations in Chemical Characteristics of the Citrus Orchard Soils as a Function of Years of Cultivation (제주도(濟州道) 토양(土壤)의 화학적(化學的) 특성(特性) 조사(調査) 연구(硏究) -II. 경작년대(耕作年代)에 따른 감귤원(柑橘園) 토양(土壤)의 화학적(化學的) 특성(特性) 변화(變化))

  • Yoo, Sun-Ho;Song, Kwan-Cheol
    • Korean Journal of Soil Science and Fertilizer
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    • v.17 no.2
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    • pp.161-166
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    • 1984
  • The Cheju citrus orchards have been chemically fertilized with both phosphates high in Ca and Mg contents and potassium. The amount of chemical fertilizers consumed per unit area of cultivated land and the ratios of $P_2O_5$ and $K_2O$ to N in chemical fertilizers applied were much higher in the Cheju Island than those of the Korean mainland. These trends were particularly prominant in Southern Cheju where 70% of the Cheju citrus orchards are located. As the result of heavy applications of phosphate fertilizers, the available phosphorus of citrus orchard soils increased with increasing number of years under cultivation. The available phosphorus of sub-soil increased slightly with the number of years under cultivation compared to that of surface soil. Base saturation and pH increased with the number of years under cultivation, inasmuch as exchangeable bases such as Ca, Mg and K increased predominantly, but the cation exchange capacity did not vary in the citrus orchard soils.

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Development of Hydraulic Jet Dredge ( 2 ) - Field Experiment of Hydraulic Jet Dredge for Catching Surf Clam - (분사식 행망의 개발에 관한 연구 ( 2 ) - 분사식 개량조개 시험행망의 현장실험 -)

  • 고관서
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.27 no.4
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    • pp.266-277
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    • 1991
  • To catch the surf clam, Mactra chinensis, in sand bottom using the excavating performance of water jet, the authors had constructed the experimental hydraulic jet dredge by the result of water tank experiment of previous report, and also were carried out the field experiments in the surf clam fishing ground near Kunsan, Korea from 5th to 30th of October, 1990. The results obtained are as follows. 1) Excavating depth was more than 10~11cm at the 1500cm/s water-jet velocity in the fine sand and muddy sand. 2) Towing tention was only 105$\pm$5kg in the 6.7cm/s towing speed. 3) Average catch amount per unit towing area was 0.42kg/m super(2) and it was 1.2~1.6 times comparing on the conventional dredge. 4) Experimental hydraulic jet dredge did not nearly brake the surf clam. 5) Turbidity variation by the water jet of dredge was not serious in the fishing ground; On the surface, when the depth is more than 5.2m, turbidity variation was not found at all, and on the 3m layer above the bottom, turbidity variations was increased 9~11ppm at 1m backward from the dredge, but it was gradually decrease, and it was nearly not at 9m backward from the dredge.

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