• Explosives and Blasting
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• v.34 no.4
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• pp.1-9
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• 2016

For underwater steel structure, cut that underwater shaped charge device that combines a spring hose, which is an external device of pressure resistance and flexibility with flexible shaped charge, was invented. As a basic experiment for an optimum condition design, an penetration performance was compared by external device shape. To evaluate the result of an experiment, image analysis was carried out after obtaining the model by using the liquid rubber for the penetrated steel plate. To simulate the penetrating process of shaped charge, the AUTODYN program has been used. As a result of analysis, while the average penetration depth of circular and square shaped external devices were similar, the penetration quality was more uniform in the case of circle. In addition, water infiltration occurred in square case, displacement and strain rate according to the increase of the water pressure were measured high.

• The Journal of Engineering Geology
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• v.27 no.3
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• pp.305-312
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• 2017

The most effective way to distinguish subsurface interfaces that produce various geophysical responses is through the integration of multiple geophysical methods, with each method detecting both a complementary and unique set of distinct physical properties relating to the subsurface. In this study, shallow seismic reflection (SSR) and ground penetrating radar (GPR) surveys were conducted at the Cheongju-Gadeok site of the Korea National Groundwater Monitoring Network to map the water table, which was measured at 12 m depth during the geophysical surveys. The water table proved to be a good target reflector in both datasets, as the abrupt transition from the overlying unsaturated weathered rock to the underlying saturated weathered rock yielded large acoustic impedance and dielectric constant contrasts. The two datasets were depth converted and integrated into a single section, with the SSR and GPR surveys conducted to ensure subsurface imaging at approximately the same wavelength. The GPR data provided detailed information on the upper ~15 m of the section, whereas the SSR data imaged structures at depths of 10-45 m. The integrated section thus captured the full depth coverage of the sandy clay, water table, weathered rock, soft rock, and hard rock structures, which correlated well with local drillcore and water table observations. Incorporation of these two geophysical datasets yielded a synthetic section that resembled a simplified aquifer model, with the best-fitting seismic velocity, dielectric constant, and porosity of the saturated weathered layer being $v_{seismic}=1000m/s$, ${\varepsilon}_r=16$, and ${\phi}=0.32$, respectively.

• Journal of the Korean Society of Industry Convergence
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• v.14 no.2
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• pp.59-65
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• 2011

$CO_2$ Welding which uses $CO_2$ instead of inert gas is most widely used in industrial sites. Welding rod for $CO_2$ Welding is roughly divided into solid wire and flux cored wire. $CO_2$ Welding has higher efficiency than any other welding methods, and also economic and speedy to handle, that's why is used frequently for welding general structures. As most of studies about $CO_2$ Welding are focused on metallurgical changes of successful joints, they developed theories about the change of configuration on weld parts. This study is especially focused on not only the change of configuration on weld parts, but also the change of the penetrating depth through changing the position of welding torch. For inspection, applied AWS A5.20 E70-1 among welding wires and fixed moving angles of torch, but controled the values of voltage and the position of welding. Also Automatic Feed Mechanism is used for exact movement of material, specimen is a piece of steel for general structures. By measuring and analyzing the configuration of sliced section and the values of welding leg length and welding throat after welding, the outcome about the changes turned out.

• Journal of Korean Neurosurgical Society
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• v.29 no.5
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• pp.623-627
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• 2000

Objective : Spontaneous lumbar epidural hematoma is a rare entity, although the precipitating factors such as anticoagulation therapy frequently precede it. The authors report four cases of surgically confirmed spontaneous epidural hematoma mimicking lumbar disc herniation. Methods : Between 1995 and 1998, four patients with spontaneous lumbar epidural hematoma were diagnosed. The clinical findings which are identical to that of acute disc herniation are included in this study. The operative findings and radiological characteristics are also included. Results : The magnetic resonance(MR) image findings demonstrated epidural lesions of intermediate to low signal intensity equivalent to those of normal discs on $T_1$-weighted images, and epidural lesions of high signal intensity higher than these normal discs on a $T_2$-weighted image. The image findings also showed rim enhanced pattern of the gadolinium-enhanced $T_1$-weighted MR images. All of the hematomas was associated with a small concomitant disc herniation or underlying annular tear. Conclusion : The authors speculate that spontaneous lumbar epidural hematoma results from tearing of the fragile penetrating vein caused by underlying disc or annulus disruption between Batson' plexus and vertebral body.

• Clinical and Experimental Pediatrics
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• v.48 no.10
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• pp.1143-1143
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• 2005

The traumatic ventricular septal defect (VSD) is a rare but potentially life threatening complication of chest wall injury. The traumatic VSD occurs in up to 4.5% of penetrating cardiac trauma. Most of the patients are usually operated on because of heart failure and/or significant left-to-right shunt. The feasibility of surgical repair under cardiopulmonary bypass may be affected by coexisting pulmonary, cerebral or other vascular injuries. Transcatheter closure of VSD is being considered as an alternative therapeutic modality to surgery in order to avoid the potential risk of cardiopulmonary bypass. We report a patient who underwent a successful transcatheter closure of VSD with an $Amplatzer^{(R)}$ VSD occluder. The patient had a residual VSD with significant left-to-right shunt after surgical repair of post-traumatic VSD using cardiopulmonary bypass.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.1
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• pp.11-17
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• 2017

Crohn's disease (CD) is a chronic inflammatory bowel disease with multifactorial causes including environmental and genetic factors. Several studies have demonstrated that the organic cation/carnitine transporter 1 (OCTN1) non-synonymous variant L503F is associated with susceptibility to CD. However, it was reported that L503F is absent in Asian populations. Previously, we identified and functionally characterized genetic variants of the OCTN1 promoter region in Koreans. In that study, four variants demonstrated significant changes in promoter activity. In the present study, we determined whether four functional variants of the OCTN1 promoter play a role in the susceptibility to or clinical course of CD in Koreans. To examine it, the frequencies of the four variants of the OCTN1 promoter were determined by genotyping using DNA samples from 194 patients with CD and 287 healthy controls. Then, associations between genetic variants and the susceptibility to CD or clinical course of CD were evaluated. We found that susceptibility to CD was not associated with OCTN1 functional promoter variants or haplotypes showing altered promoter activities in in vitro assays. However, OCTN1 functional promoter haplotypes showing decreased promoter activities were significantly associated with a penetrating behavior in CD patients (HR=2.428, p=0.009). Our results suggest that the OCTN1 functional promoter haplotypes can influence the CD phenotype, although these might not be associated with susceptibility to this disease.

• Journal of the Korean Applied Science and Technology
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• v.21 no.2
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• pp.117-123
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• 2004

According to increase of using quantity, people interested in the environmental influence by synthetic detergent. The main visible form when synthetic detergent dissolved in water is generating foams. This foam makes coating over water surface and prevents oxygen penetrating in water and make water more polluted with that result. To analyze, components and origins of the foam, and to make clear its environmental influence in this study. The analyzing objects are introducing water of sewage treatment plant from the a tributary to the Han River. After analysis, reached the conclusion like below, Analyzing foams and introducing water by sublation method, average return rate of standard LAS (1.0ppm) is 90%. LAS contents of foams analyzed by UV photometric method and HPLC method are 35.0ppm and 44.5ppm each, and AOS contents of foams analyzed by the same method are 0.6ppm and 0.4ppm each. We can find out by this study's analyzing results that the main components of foams are anion surfactant, it's content and in case of capric acid linoleic acid, it's contents.

• Journal of Microbiology and Biotechnology
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• v.29 no.11
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• pp.1707-1716
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• 2019

The development of new antimicrobial agents is essential for the effective treatment of diseases such as sepsis. We previously developed a new short peptide, Pap12-6, using the 12 N-terminal residues of papiliocin, which showed potent and effective antimicrobial activity against multidrug-resistant Gram-negative bacteria. Here, we investigated the antimicrobial mechanism of Pap12-6 and a newly designed peptide, Pap12-7, in which the 12^th Trp residue of Pap12-6 was replaced with Val to develop a potent peptide with high bacterial selectivity and a different antibacterial mechanism. Both peptides showed high antimicrobial activity against Gram-negative bacteria, including multidrug-resistant Gram-negative bacteria. In addition, the two peptides showed similar anti-inflammatory activity against lipopolysaccharide-stimulated RAW 264.7 cells, but Pap12-7 showed very low toxicities against sheep red blood cells and mammalian cells compared to that showed by Pap12-6. A calcein dye leakage assay, membrane depolarization, and confocal microscopy observations revealed that the two peptides with one single amino acid change have different mechanisms of antibacterial action: Pap12-6 directly targets the bacterial cell membrane, whereas Pap12-7 appears to penetrate the bacterial cell membrane and exert its activities in the cell. The therapeutic efficacy of Pap12-7 was further examined in a mouse model of sepsis, which increased the survival rate of septic mice. For the first time, we showed that both peptides showed anti-septic activity by reducing the infiltration of neutrophils and the production of inflammatory factors. Overall, these results indicate Pap12-7 as a novel non-toxic peptide with potent antibacterial and anti-septic activities via penetrating the cell membrane.

• KIEAE Journal
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• v.10 no.4
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• pp.137-145
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• 2010

Active sunlighting systems have been applied to deliver sunlight into the indoor space where natural light is insufficient, mainly because of the congested high-rise buildings in urban areas. Among various active sunlighting systems, a mirror sunlighting system which is simple structure and economically reasonable has been widely used in different types of spaces such as underground, north facing place and atrium. This study was to evaluate the mirror sunlighting systems, which were consisted of the first mirror of $3.5m{\times}2.5m$, the eight sets of the second mirrors of $1.0m{\times}1.25m$ and a sun tracker. Ten sets of the systems were installed for 40 apartment living rooms, the configuration of $3.5m(W){\times}4.0m(D){\times}2.5m(H)$ where sunlighting were not possible due to high retaining walls located in the front of the living rooms. The 45 HOBO data logger sensors for the indoor illuminance were equipped and 2 Li-cor photometers for outdoor illuminance. Both indoor and outdoor horizontal illuminances were monitored every second from 9am to 3pm on 17 January 2010 under clear sky condition. The results showed that the indoor illuminance of installed mirror sunlighting system was significant relationship with outdoor illuminance and increased the indoor illuminance level by 4.2 times on the whole floor space, by 8 times on the sun patch space of 6m2 and even by 2 times on the no sun patch space. In addition, the luminous conditions of the living room under real sky conditions met the KS recommendation for difficult task (600-1000-1500 lux) such as sewing and reading on whole floor space and sun patch space. It was proved that the benefits of mirror sunlighting systems included an effective technology for penetrating daylight into indoors where sunlighting was not possible and improving occupants' satisfaction and health, and contributing to energy saving in apartments during daytime.

• Journal of the Korean Society for Railway
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• v.12 no.6
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• pp.1024-1029
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• 2009

According to increase of massive concrete structures, Thermal crack done by heat of hydration have been increased in a process of the execution. In case of a subway concrete box structure, thickness of structures are almost over 1 meter, and penetrating crack by external restraint takes a bad effect on the durability with a water leakage and deterioration in especially concrete wall. A try of shortening a constructing period often occurs as subway is generally constructed according to a road to decrease a traffic jam. The research proposes executing method by skipping one block as a plan of shortening a constructing period and investigate an influence on thermal cracking control. Additionally, sensitivity analysis is accomplished by changing a height of a concrete wall, and concrete placing and air temperature met with a field condition.