• Title/Summary/Keyword: pathological findings

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Vision transformers for endoscopic pathological findings classification (내시경 병리소견 분류를 위한 비전 트랜스포머)

  • Ayana, Gelan;Choe, Se-woon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.05a
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    • pp.396-398
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    • 2022
  • The endoscopic pathological findings of gastrointestinal tract (GIT) are important in the early diagnosis of colorectal cancer. Deep learning based on convolutional nueral network (CNN) has been implemented to solve the subjective analysis problem and to increase the performance of early detection of pathological findings. However, the desired performance is yet to be achieved and CNNs are computationally complex. To solve these problems, in this paper, we propose a vision transformer based endoscopic pathological findings classification for the early detection of colorectal cancer. Publicly available endoscopic images with three pathological findings, including esophagitis, polyps, and ulcerative colitis, each with 1000 images were used. Using our approach, we have achieved a test accuracy of 98% in classifying the three pathological findings.

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Pathological findings of swine dysentery (돼지 적리의 병리학적 소견)

  • 김순복;문운경
    • Korean Journal of Veterinary Service
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    • v.23 no.3
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    • pp.219-221
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    • 2000
  • This experiment was done to determine pathological findings of swine dysentery naturally occurred in Korea. Clinical sign was characterized by mucohemorrhagic diarrhea. Characteristic mucofibrinous lesions composed of fibrin, mucus, and sloughed cell debri were mostly limited to the large intestine of affected pjgs. A myriad of coiled spirochetes were detected in the colonic crypts.

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Radiological Findings of Lung Cancer: Focus on Atypical Pattern (폐암의 방사선 소견(비전형적 소견을 중심으로))

  • Sung, Dong-Wook
    • Tuberculosis and Respiratory Diseases
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    • v.58 no.6
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    • pp.554-561
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    • 2005
  • The clinical and radiographic findings of lung cancer have been well established many journals. Even if the radiographic findings of lung cancer show a typical pattern, the specific cell type of lung cancer sometimes needs to be determined prior to a pathological diagnosis. For example, the usual finding of a squamous cell carcinoma is similar to other cancer types such as an adenocarcinoma or a small cell carcinoma but with a lower incidence. Therefore, it should not be used to make a diagnosis of the cell type prior to a pathological diagnosis. Many unusual findings of lung cancer, so called atypical pattern have been reported, but atypical findings are widely accepted. The more important thing is not to diagnose a specific cell type of cancer but to differentiate it from other benign conditions such as tuberculosis, fungal infections or organizing pneumonia. This paper presents typical information of the cell type of lung cancer along with the atypical radiographic findings.

Secondary Circulating Tumor Cells (CTCs) but not Primary CTCs are Associated with the Clinico-Pathological Parameters in Chilean Patients With Colo-Rectal Cancer

  • Murray, Nigel P;Albarran, Vidal;Perez, Guillermo;Villalon, Ricardo;Ruiz, Amparo
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4745-4749
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    • 2015
  • Background: The aim of this study was to assess detection of circulating tumor cells (CTC) using anti-CEA pre and post surgery in Chilean patients with colo-rectal cancer. Materials and Methods: The presence of CTCs was evaluated in 80 colorectal cancer patients pre and post surgery using standard immunocytochemistry and the results were compared with findings for standard clinico-pathological parameters. Results: In patients presurgery CEA (+) CTCs were frequently found, with no relation to tumor size or nodal status. After surgery, the presence of CTCs was associated with such clinico-pathological parameters. The frequency of CTC detection in node positive patients did not change after surgery. In patients with metastasis there was also no change in the frequency of CTC detection, and clusters of 3 or more CTCs were evident. Conclusions: Secondary CTCs are associated with clinico-pathological parameters only after surgical removal of the primary tumor, and might be important in identifying patients at high risk of relapse. Primary CTCs detected before surgical removal are frequently found, are not associated with the clinico-pathological parameters and might have a role in cancer screening. These findings suggest the need for studies with a larger population of patients.

Pathological observations of rabbit hemorrhagic disease (토끼 출혈병의 병리학적 관찰)

  • 문운경;하준일;인민권;김순복;곽수동
    • Korean Journal of Veterinary Service
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    • v.23 no.4
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    • pp.309-312
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    • 2000
  • Pathological findings of natural cases of rabbit hemorrhagic disease was investigated. Clinically inappentence, increase in body temperature, depression, bloody foam from nostrils, and sudden death were recognized. Characteristic anatomical findings were hemorrhages in the lungs, liver, kidneys, and heart. Intestinal catarrh and retention of turbid urine in urinary bladder were also often observed. Severe .necrosis of hepatic cells, massive hemorrhages in many organs and membranous glomerulonephritis with hyaline droplet formation were characteristic changes under the microscopy. Perivascular cuffing of brain and catarrhal enteritis were also seen in many cases.

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Pathological findings of leucocytozoonosis in chickens (닭 leucocytozoonosis의 병리학적 소견)

  • 문운경;김순복
    • Korean Journal of Veterinary Service
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    • v.23 no.3
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    • pp.223-226
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    • 2000
  • Pathological findings of leucocytozoonosis naturally occurred in Korea are described. Most of the affected chickens showed paleness of comb and wattle, egg drop, approximately 20 to 30% mortality, green diarrhea, anorexia and weakness. On the blood smear merozoits and gametocytes were detected. At necropsy, petechial and ecchymotic hemorrhages in liver, kidney, heart, muscle, and splenomegaly were frequently observed. Microscopically schizonts with fine granular merozoits were often detected in kidney, intestine, brain, lung, myocardium, muscle, liver with cenrilobular fatty change, and spleen.

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Problems in the Pathologic Diagnosis of Suspected Lung Cancer

  • Soo Han Kim;Mi-Hyun Kim;Min Ki Lee;Jung Seop Eom
    • Tuberculosis and Respiratory Diseases
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    • v.86 no.3
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    • pp.176-182
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    • 2023
  • Since the introduction of low-dose computed tomography (CT) screening for patients at high risk of lung cancer, the detection rate of suspicious lung cancer has increased. In addition, there have been many advances in therapeutics targeting oncogenic drivers in non-small cell lung cancer. Therefore, accurate pathological diagnosis of lung cancer, including molecular diagnosis, is increasingly important. This review examines the problems in the pathological diagnosis of suspected lung cancer. For successful pathological diagnosis of lung cancer, clinicians should determine the appropriate modality of the diagnostic procedure, considering individual patient characteristics, CT findings, and the possibility of complications. Furthermore, clinicians should make efforts to obtain a sufficient amount of tissue sample using non- or less-invasive procedures for pathological diagnosis and biomarker analysis.

Schistosomiasis Combined with Colorectal Carcinoma Diagnosed Based on Endoscopic Findings and Clinicopathological Characteristics: A Report on 32 Cases

  • Liu, Wei;Zeng, Hong-Ze;Wang, Qi-Ming;Yi, Hang;Mou, Yi;Wu, Chun-Cheng;Hu, Bing;Tang, Cheng-Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4839-4842
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    • 2013
  • Aims and Background: To improve understanding of the relationship between schistosome-related enteropathy and colorectal carcinoma with particular focus on endoscopic findings and clinicopathological characteristics of colonic schistosomiasis. Materials and Methods: All cases of intestinal schistosomiasis diagnosed at West China Hospital, Chengdu, China, between October 2006 and October 2012 were included in this study. A total of 179 cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected for analysis and the demographics, symptoms, endoscopic findings and clinicopathological characteristics were retrospectively evaluated. Results: Of the 179 colonic schistosomiasis patients, 32 combined with colorectal cancer (CRC) were found, between the ages of 44 and 85 years (24 males, 75%). These 32 lesions were classified as 12 endophytic/ulcerative (37.5%), 10 exophytic/fungating (31.2%), 4 annular (12.5%), 3 giant polypus (9.4%), and 3 IIc (superficial depressed type) (9.4%). The segments of rectum and sigmoid colon were involved in 19 patients (59.4%) and 6 patients (18.8%), respectively. The histopathologic types were classified as follows: 30 welldifferentiated adenocarcinomas, one mucinous adenocarcinoma and one poorly differentiated adenocarcinoma. The pathological findings suggest colorectal malignancy with deposited schistosome ova. Conclusions: Chronic schistosomal infestation has a probable etiological role in promoting genesis of colorectal neoplasms.

A clinico-pathological observation in dogs associated with zinc-deficient dermatosis (개에 발생한 아연부족성 피부병의 임상병리학적 관찰)

  • Oh, Kyu-Shil;Lee, Cha-Soo;Han, Hee-Seak;Chung, Jae-Yong;Park, Chung-Kyu
    • Korean Journal of Veterinary Pathology
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    • v.3 no.1
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    • pp.45-50
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    • 1999
  • Canine dermatosis associated with zinc deficiency naturally occurred in three districts of Kyungpook. A diagnosis was made by clinical findings, clinico-pathological examinations, skin biopsy, and therapeutic tests. The result was diagnosed as a zinc-deficient dermatosis. The disease occurred in rapidly growing Tosa-dog hybrids 5 to 7 months old. Skin lesions included erytherma, alopecia, crusting, scaling around the mouth, eyes, legs and tail. Clinico-pathological findings were decreased serum zinc levels, slightly increased white blood cells, and secondary Staphylococcus intermedius infection of the crusts. The skin biopsies for histopathological examination revealed marked parakeratotic hyperkeratosis. The patients with skin lesions were successfully treated by zinc methonine(Zinpro) medication In conclusion, serum zinc level and skin biopsy are very helpful in diagnosis of canine zinc-deficient dermatosis.

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Effects of a Family Education Program for Families of Pathological Gamblers (병적도박자 가족교육 프로그램의 적용효과)

  • Hong, Jungah;Yang, Soo
    • Journal of Korean Academy of Nursing
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    • v.43 no.4
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    • pp.497-506
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    • 2013
  • Purpose: This study was done to examine the intervention effects on the family of a family education program for pathological gamblers based on Community Reinforcement and Family Training (CRAFT). Methods: A quasi-experimental, nonequivalent control group pretest-posttest design was used. The participants were 44 families of pathological gamblers from G center in Gyung-gi Province and 5 Gam-Anon groups in Seoul City and Gyung-gi Province. The experimental group (n=22) attended the 6 weekly 2 hour-long CRAFT family education program. The control group (n=22) attended the 12-step program of Gam-Anon. Data were collected from November, 2011 to May, 2012. Results: Compared with the control group, the experimental group showed significant decrease in depression (p=.001) and state anger (p=.039). There were no significant differences between groups in the level of interpersonal communication, trait anger, the mode of anger expression and self-esteem. Conclusion: Findings from this study suggest that the CRAFT family education program is effective in decreasing depression and state anger in families of pathological gamblers.