• Title/Summary/Keyword: path-dependent

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A Study on the Foreign Direct Investment Determinants of Chinese Manufacturing Firms into local Korea (해외직접투자 결정요인에 관한 실증연구 - 중국 제조 기업의 대한국 해외직접투자를 중심으로 -)

  • Shin, Kwang-Ha;Yoon, Seong-Hwan;Park, Myung-Chan
    • International Area Studies Review
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    • v.13 no.3
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    • pp.163-190
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    • 2009
  • This study tries to analyze the investment determinants of Chinese firms in local Korea, where the Chinese investing ones have been operating since in the middle of 1990s. The main purpose can be mentioned to test empirically some relations between the investment determinants of Chinese firms and the investment types. In detail speaking, the dependent variables of investment types are classified with sole venture and joint venture, while the independent ones are sorted based on the previous studies with the 2 following factors like the competitive advantages of Chinese firms, and the location advantages of local Korea. This study is conducted as the following: the survey of Chinese firms engaging in investment activities in there is implemented by collecting questionnaires. And for testing the hypothesis, the path analysis of structural equation modeling is activated with SPSS. 12.0 and AMOS 11.0 for windows.

Differential Expression Profiling of Salivary Exosomal microRNAs in a Single Case of Periodontitis - A Pilot Study

  • Park, Sung Nam;Son, Young Woo;Choi, Eun Joo;You, Hyung-Keun;Kim, Min Seuk
    • International Journal of Oral Biology
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    • v.43 no.4
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    • pp.223-230
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    • 2018
  • Exosomes are Nano-sized lipid vesicles secreted from mammalian cells containing diverse cellular materials such as proteins, lipids, and nucleotides. Multiple lines of evidence indicate that in saliva, exosomes and their contents such as microRNAs (miRNAs) mediate numerous cellular responses upon delivery to recipient cells. The objective of this study was to characterize the different expression profile of exosomal miRNAs in saliva samples, periodically isolated from a single periodontitis patient. Unstimulated saliva was collected from a single patient over time periods for managing periodontitis. MicroRNAs extracted from each phase were investigated for the expression of exosomal miRNAs. Salivary exosomal miRNAs were analyzed using Affymetrix miRNA arrays and prediction of target genes and pathways for its different expression performed using DIANA-mirPath, a web-based, computational tool. Following the delivery of miRNA mimics (hsa-miR-4487, -4532, and -7108-5p) into human gingival fibroblasts, the expression of pro-inflammatory cytokines and activation of the MAPK pathway were evaluated through RT-PCR and western blotting. In each phase, 13 and 43 miRNAs were found to be differently expressed $({\mid}FC{\mid}{\geq}2)$. Among these, hsa-miR-4487 $({\mid}FC{\mid}=9.292005)$ and has-miR-4532 $({\mid}FC{\mid}=18.322697)$ were highly up-regulated in the clinically severe phase, whereas hsa-miR-7108-5p $({\mid}FC{\mid}=12.20601)$ was strongly up-regulated in the clinically mild phase. In addition, the overexpression of miRNA mimics in human gingival fibroblasts resulted in a significant induction of IL-6 mRNA expression and p38 phosphorylation. The findings of this study established alterations in salivary exosomal miRNAs which are dependent on the severity of periodontitis and may act as potential candidates for the treatment of oral inflammatory diseases.

Academic Achievement of Nursing College Students according to Academic Self-efficacy: The Mediating Effect of Major Satisfaction (간호대학생의 학업적 자기효능감이 학업성취도에 미치는 영향: 전공만족도의 매개효과)

  • Kim, Juyeoun;Kim, Hyeon Ok;Lee, Myungha
    • Child Health Nursing Research
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    • v.25 no.2
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    • pp.205-213
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    • 2019
  • Purpose: The purpose of this study was to examine the mediating effect of major satisfaction in the relationship between academic self-efficacy and academic achievement among nursing students. Methods: Data were collected from 142 nursing students from March 5 to March 9, 2018, and the collected data were analyzed using SPSS version 21.0 for Windows. Results: Academic self-efficacy had a significant effect on both major satisfaction (${\beta}=.31$, p<.001), and academic achievement (${\beta}=.43$, p<.001). The parameter of major satisfaction was found to have a significant effect on the dependent variable, academic achievement (${\beta}=.22$, p=.007), and the independent variable, academic self-efficacy, also had a significant effect on academic achievement (${\beta}=.39$, p<.001). Thus, major satisfaction was found to have a partial mediating effect on the relationship between academic self efficacy and academic achievement. The Sobel test showed that the path of the academic achievement and academic self efficacy variables was significantly mediated by major satisfaction (Z=2.99, p=.003). Conclusion: Academic self-efficacy was found to affect academic achievement, and major satisfaction was found to play a partial mediating role in the relationship between academic self efficacy and academic achievement.

An Analysis on the Change of Existing Building-related System in Urban Parks (도시공원 내 기존 건축물 제도의 변천 과정 분석)

  • Oh, Chang-Song;Sim, Ji-Soo
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.35 no.10
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    • pp.115-126
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    • 2019
  • Existing buildings in urban parks are a kind of thing that has been settled and occupied on the site of an unexecuted park. The aim of this study is to identify nature by analyzing the causality and path-dependency through the transformation of the relevant system. The scope of the study was set up as a system for the occupancy of urban parks from 1934 when the building restriction system was established to 2000 when purchase claim (매수청구권) was introduced. The method of study was to get correlation by harmonizing the external and internal mechanisms affecting the relevant institution. The related system showed a modest change in the fourth stage, polymerizing the initial system. In the 1950s and 1960s, the existing buildings in urban parks were 'disguised' by government and the 'regulation' principle was applied since 1967. In the 1980s, the principle of 'protection' and 'support' for parks was added, but in the 1990s, the principle of regulation began to be lifted as the long-term unexecuted urban park (장기미집행 도시공원) problem continued for more than 60 years. Although the public concept of land ownership (토지공개념) has worked strongly for nearly 30 years since 1960, the system has developed into a form of deregulation since 1980. The nature of the relevant institution is first, dependent on the higher-level system and vertical. Second, it implies a conflict of restrictions and acceptance. Third, it is a temporary measure of the park problem. Therefore, the relevant system has long been enhancing the encroachment requirements on urban parks, so fundamental readjustment is needed in the future.

Impact of Outsourcing Risk on Corporate Performance (아웃소싱의 리스크가 기업성과에 미치는 영향)

  • Kim, Lark Sang
    • Journal of Digital Convergence
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    • v.19 no.2
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    • pp.175-182
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    • 2021
  • In this study, small and medium-sized manufacturing and distribution businesses were asked to demonstrate how the risks that could arise from implementing ITOs affect their performance. Small and medium-sized enterprises that want to reduce costs or secure competitiveness through outsourcing ITO conducted research to identify and analyze risks of ITO and improve corporate performance. Strategic, technical, and financial risks were selected as independent variables for analysis by the survey method. In addition, relationship risk was selected as a parameter and corporate performance was selected as a dependent variable to conduct a path analysis. The analysis showed that the variables injected as independent variables had indirect and total effects on corporate performance. This can be interpreted as the higher the level of awareness of strategic and technological risks and financial risks, the higher the level of relational risk, and thus the positive impact on corporate performance. We expect to improve corporate performance through analysis of more and more risk factors in the future.

Linear Energy Transfer Dependence Correction of Spread-Out Bragg Peak Measured by EBT3 Film for Dynamically Scanned Proton Beams

  • Lee, Moonhee;Ahn, Sunghwan;Cheon, Wonjoong;Han, Youngyih
    • Progress in Medical Physics
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    • v.31 no.4
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    • pp.135-144
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    • 2020
  • Purpose: Gafchromic films for proton dosimetry are dependent on linear energy transfers (LETs), resulting in dose underestimation for high LETs. Despite efforts to resolve this problem for single-energy beams, there remains a need to do so for multi-energy beams. Here, a bimolecular reaction model was applied to correct the under-response of spread-out Bragg peaks (SOBPs). Methods: For depth-dose measurements, a Gafchromic EBT3 film was positioned in water perpendicular to the ground. The gantry was rotated at 15° to avoid disturbances in the beam path. A set of films was exposed to a uniformly scanned 112-MeV pristine proton beam with six different dose intensities, ranging from 0.373 to 4.865 Gy, at a 2-cm depth. Another set of films was irradiated with SOBPs with maximum energies of 110, 150, and 190 MeV having modulation widths of 5.39, 4.27, and 5.34 cm, respectively. The correction function was obtained using 150.8-MeV SOBP data. The LET of the SOBP was then analytically calculated. Finally, the model was validated for a uniform cubic dose distribution and compared with multilayered ionization chamber data. Results: The dose error in the plateau region was within 4% when normalized with the maximum dose. The discrepancy of the range was <1 mm for all measured energies. The highest errors occurred at 70 MeV owing to the steep gradient with the narrowest Bragg peak. Conclusions: With bimolecular model-based correction, an EBT3 film can be used to accurately verify the depth dose of scanned proton beams and could potentially be used to evaluate the depth-dose distribution for patient plans.

Effect of Shoulder Stabilization Exercise with Pelvic Compression Belt Application on Muscle Activity, Pain and Function of Muscles around Shoulder Joint in Subjects with Round Shoulders (둥근 어깨가 있는 대상자에게 골반 압박 벨트 적용을 동반한 어깨 안정화 운동의 수행이 어깨관절 주위 근육의 근활성도와 통증 및 기능에 미치는 영향)

  • Kim, Chung-Yoo;Lee, Yeon-Seop;Kim, Hyeon-Su
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.4
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    • pp.199-207
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    • 2022
  • Purpose : The purpose of this study is to investigate the effect of shoulder stabilization exercise accompanied by application of a pelvic compression belt on the muscle activity, pain and function of the muscles around the shoulder in subjects with round shoulders. Methods : For the study method, 28 students who were enrolled in K University with a distance of 1 cm or more between the clavicle of the peak and the outer ear path were selected through GPS 400 global postural analysis system measurement. The subjects were randomly assigned to 14 participants in the group wearing a pelvic compression belt and 14 patients in the group not wearing a pelvic compression belt. In all subjects, the muscle activities of the middle trapezius, lower trapezius, and serratus anterior muscles and the shoulder pain disorder index (SPADI) were measured. The intervention was performed 3 times a week for 4 weeks, and the applied intervention was push-up plus and modified prone cobra exercise. The muscle activities of the middle trapezius, lower trapezius, and serratus anterior muscles and SPADI score were compared using dependent t test before and after intervention. Results : In this study, both groups showed that the muscle activity of the middle trapezius, lower trapezius, and serratus anterior significantly increased after the intervention compared to before the intervention. On the other hand, SPADI showed no significant difference. Conclusion : The results of this study showed that muscle activity in the peri-shoulder joint was increased after push-up plus and modified prone cobra exercise in both groups, regardless of whether pelvic compression was applied or not. Therefore, it was found that shoulder stabilization exercise using the pelvic compression belt also contributed to the enhancement of muscle activity in the joints around the shoulder.

Development of an optimal protocol to induce capacitation of boar spermatozoa in vitro

  • Seung-Ik Jang;Jae-Hwan Jo;Eun-Ju Jung;Woo-Jin Lee;Ju-Mi Hwang;Jeong-Won Bae;Woo-Sung Kwon
    • Journal of Animal Reproduction and Biotechnology
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    • v.37 no.4
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    • pp.285-291
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    • 2022
  • In 1951, Colin Russell Austin and Min Chueh Chang identified "capacitation", a special process involving ejaculated spermatozoa in the female reproductive tract. Capacitation is a phenomenon that occurs in vivo, but almost all knowledge of capacitation has been obtained from in vitro studies. Therefore, numerous trials have been performed to establish in vitro capacitation methods for various studies on reproduction. Although a series of studies have been conducted to develop an optimal protocol for inducing capacitation, most have focused on identifying the appropriate chemical compounds to induce the capacitation of boar spermatozoa in vitro. Therefore, the purpose of this study was to identify the optimal incubation time for inducing capacitation in vitro. Duroc semen was incubated for various periods (60, 90, and 120 min) to induce capacitation. Sperm function (sperm motility, motion kinematic parameters, and capacitation status) was evaluated. The results showed that total sperm motility, rapid sperm motility, progressive sperm motility, curvilinear velocity, and average path velocity significantly decreased in a time-dependent manner. However, the capacitation status did not show any significant changes. Taken together, these results indicate that an incubation time of more than 60 min suppresses sperm motility and motion kinematic parameters. Therefore, we suggest that 60 min may be the best incubation time to induce capacitation without negative effects on sperm motility and motion kinematics in boar spermatozoa in vitro.

Feasibility of Ocean Survey by using Ocean Acoustic Tomography in southwestern part of the East Sea (동해 남서해역에서 해양음향 토모그래피 운용에 의한 해양탐사 가능성)

  • Han, Sang-Kyu;Na, Jung-Yul
    • The Journal of the Acoustical Society of Korea
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    • v.13 no.6
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    • pp.75-82
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    • 1994
  • The ray paths and travel times of sound wave in the ocean depend on the physical properties of the propagating media. Ocean Acoustic Tomography(OAT), which is inversely estimate the travel time variations between fixed sources and receivers the physical properties of the corresponding media can he understood. To apply ocean survey technology by using the OAT, the tomographic procedure requires forward problem that variation of the travel times be identified with the variability of the medium. Also, received signals must be satisfied the necessary conditions of ray path stability, identification and resolution in order for OAT to work. The canonical ocean has been determined based on the historical data and its travel time and ray path are used as reference values. The sound speed of canonical ocean in the East Sea is about 1523 m/s at the surface and 1458 m/s at the sound channel axis(400m). Sound speeds in the East Sea are perturbed by warm eddy whose horizontal extension is more than 100 km with deeper than 200 m in depth scale. In this study, an acoustic source and receiver are placed at the depth above the sound channel axis, 350 m, and are separated by 200 km range. Ray paths are identified by the ray theory methed in a range dependent medium whose sound speeds are functions of a range and depth. The eigenray information obtained from interpolation between the rays bracketing the receiver are used to simulate the received signal by convolution of source signal with the eigenray informations. The source signal is taken as a 400 Hz rectangular pulse signal, bandwidth is 16 Hz and pulse length is 64 ms. According to the analysis of the received signal and identified ray path by using numerical model of underwater sound propagation, simulated signals satisfy the necessary conditions of OAT, applied in the East Sea.

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Trends and Issues in Social Geography in the 2000s in S. Korea: (2) Empirical Researches (2000년대 한국 사회지리학의 경향과 논제들 -(2) 경험적 연구들-)

  • Choi, Byung-Doo
    • Journal of the Korean Geographical Society
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    • v.47 no.5
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    • pp.735-754
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    • 2012
  • Korean society in the 2000 has experienced new many social and spatial issues such as the process of neoliberalism and changes in urban and spatial policies, the development of information and communication technology and reconfiguration of informational social space, radically increasing foreign immigrants and transformation to multicultural society, global warming and environmental injustice, and these new issues have promoted development of social geography in Korea. In addition to a review on them, this paper provides a review on empirical researches on traditional issues which have been dealt with in social geography in the 2000 in Korea. Even though there have been numerous sub-issues, they can be divided into two categories: one is urban and communal social geography including urban housing and residential segregation, urban social problems such as poverty, crime, education, health care, social welfare, urban and rural community building, identity, sense of place, and social movement; the other is social geography of population and migration, including population movement, aged society and social welfare for elderly people, and foreign immigrants and formation of multicultural social space. As some difficult conditions such as path-dependent process of neoliberalism, transformation toward informational, aged, and multicultural society would continue, so social geography in Korea to tackle with these external conditions should deepen its theoretical insights and widen its research issues.

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