• IEMEK Journal of Embedded Systems and Applications
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• v.11 no.2
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• pp.117-123
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• 2016

In general, PCM (Phase Change Memory) is unsuitable as a main memory because it has limitations: high read/write latency and low endurance. However, the DRAM&PCM hybrid memory with the same level is one of the effective structures for a next generation main memory because it can utilize an advantage of both DRAM and PCM. Therefore, it needs an effective page management method for exploiting each memory characteristics dynamically and adaptively. So we aim reducing an access time and write count of PCM by using an effective page replacement. According to our simulation, the proposed algorithm for the DRAM&PCM hybrid can reduce the PCM access count by around 60% and the PCM write count by 42% given the same PCM size, compared with Clock-DWF algorithm.

• Journal of the Korea Society of Computer and Information
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• v.18 no.12
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• pp.1-9
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• 2013

Even though the multiple pages TLB are effective in improving the performance, a conventional method with OS support cannot utilize multiple page sizes in user application. Thus, we propose a new multiple-TLB structure supporting multiple page sizes for high performance and low power consumption without any operating system support. The proposed TLB is organised as two parts of a S-TLB(Small TLB) with a small page size and a L-TLB(Large TLB) with a large page size. Both are designed as fully associative bank structures. The S-TLB stores small pages are evicted from the L-TLB, and the L-TLB stores large pages including a small page generated by the CPU. Each one bank module of S-TLB and L-TLB can be selectively accessed base on particular one and two bits of the virtual address generated from CPU, respectively. Energy savings are achieved by reducing the number of entries accessed at a time. Also, this paper proposed the simple 1-bit LRU policy to improve the performance. The proposed LRU policy can present recently referenced block by using an additional one bit of each entry on TLBs. This method can simply select a least recently used page from the L-TLB. According to the simulation results, the proposed TLB can reduce Energy * Delay by about 76%, 57%, and 6% compared with a fully associative TLB, a ARM TLB, and a Dual TLB, respectively.

• Molecular & Cellular Toxicology
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• v.1 no.2
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• pp.87-91
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• 2005

Although 2D-PAGE has been widely used as the primary method for protein separation, difficulties in displaying proteins with an extreme values of isoelectric paint (pI), molecular size and hydrophobicity limit the technique. In addition, time consuming steps involving protein transfer and extraction from the gel-pieces can result in sample loss. Here, we describe a novel protein separation technique with capillary size-exclusion chromatography (CSEC) for rapid protein identification from human plasma. The method includes protein fractionation along with molecular size followed by in-solution tryptic digestion and peptide analysis through reversed phase liquid chromatography (RPLC) coupled to nanoflow electrospray-tandem mass spectrometry (ESI-MS/MS). Tryptic peptides are applied an a $100\;{\mu}m\;i.d.{\times}10mm$ length pre-column and then separated on a $75\;{\mu}m{\times}200mm$ analytical column at -100 nL/min flaw rate. Proteins were identified over the wide ranges of pI (3.7-12.3) when this technique was applied to the analysis of $1-2\;{\mu}L$ of human plasma. This gel-free system provides fast fractionation and may be considered a complementary technique to SDS-PAGE in proteomics.

• IEMEK Journal of Embedded Systems and Applications
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• v.12 no.3
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• pp.169-176
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• 2017

To replace conventional DRAM, many researches have been done on nonvolatile memories. The DRAM&PCM hybrid memory is one of the effective structure because it can utilize an advantage of DRAM and PCM. However, in order to use this characteristics, pages can be replaced frequently between DRAM and PCM. Therefore, PCM still has major problem that has write-limits. Therefore, it needs an effective page management method for exploiting each memory characteristics dynamically and adaptively. So we aim reducing an average access time and write count of PCM by utilizing two locality for an effective page replacement. We proposed a page selection algorithm which is recently requested to write in DRAM and an algorithm witch uses two locality in PCM. According to our simulation, the proposed algorithm for the DRAM&PCM hybrid can reduce the PCM write count by around 22% and the average access time by 31% given the same PCM size, compared with CLOCK-DWF algorithm.

• Clinical and Experimental Reproductive Medicine
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• v.13 no.1
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• pp.39-51
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• 1986

This experiment has been done to evaluate the relationship between the follicular atresia and the protein patterns on electrophoreais of the follicular fluids in porcine ovary. The protein concentration of the follicular fluids was lower than that of serum, and gradually decreased as the follicle siae became larger. The number of protein bands of follicular fluid on electrophoresis was less than that of serum, and gradually increased as follicle size became larger. Three specific bands were detected on disc PAGE and one band(M W. 75,000) on SDS PAGE in the follicular fluids, while not in serum. One band (A) at ${\beta}$-globulin region on disc PAGE became heavier, as follicles became atretic. Two bands less than(M. W. 20,000) were detected only in the large follicular fluid. Another band(M. W. 43,000) was not detected in necrotic group, whereas all other groups showed it. It could be concluded that the component and composition of the proteins follicular fluids changes according to the follicular size during atresia. Therefore detection of the changing pattern of proteins in the follicular fluid can be used as a basic criterion for the identification of follicular atretic stage.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.12
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• pp.918-922
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• 2009

Naturally, block mapping FTL works well for sequential writes while page mapping FTL does well for random writes. To exploit their advantages, a practical FTL should be able to selectively apply a suitable scheme between page and block mappings for each write pattern. To meet that requirement, we propose a hybrid mapping FTL, which we call Janus-FTL, that distributes data to either block or page mapping areas. Also, we propose the fusion operation to relocate the data from block mapping area to page mapping area and the defusion operation to relocate the data from page mapping area to block mapping area. And experimental results of Janus-FTL show performance improvement of maximum 50% than other hybrid mapping FTLs.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.9
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• pp.24-36
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• 1996

In this paper, we discuss the errors in selectivity estimation using the multilevel grid file (MLGF). We first demonstrate that the estimatio errors stem from the uniformity assumption that records are uniformly distributed in their belonging region represented by an entry in a level of an MLGF directory. Bsed on this demonstration, we then investigate five factors affecting the accuracy of estimation: (1) the data distribution in a region (2) the number of records stored in an MLFG (3) the page size, (4) the query region size, and (5) the level of an MLFG directory. Next we present the tendancy of estimation errors according to the change of values for each factor through experiments. The results show that the errors decrease when (1) the distribution of records in a region becomes closer to the uniform one, (2) the number of records in an MLFG increases, (3) the page size decreases, (4) the query region size increases, and (5) the level of an MLFG directory employed as data distribution information becomes lower. After the definition of the granule ratio, the core formula representing the basic relationship between the estimation errors and the above five factors, we finally examine the change of estimation errors according to the change of the values for the granule ratio through experiments. The results indicate that errors tend to be similar depending on the values for the granule ratio regardless of the various changes of the values for the five factors. factors affecting the accuracy of estimation:

• Proceedings of the Korean Information Science Society Conference
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• 2003.04c
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• pp.52-54
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• 2003

Measurement is used to improve software process and to help calculating software quality. It makes software project to be control and help producing software. Measuring software scale becomes important target in software development. LOC is used to measure the size intentioned aspect and function point is used to measure the function intentioned aspect. This paper discusses measurement method using function point, which fullows proposed rule, and degree of GUI (Graphical User Interface) accesses achieved by applying this measurement to web page. Applying proposed rules to web pages (specially that use much GUI such as shopping mall or auction site), there is advantage that calculate site changes on numerical value by measuring GUI degree when do site administration or update.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.158-162
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• 2005

Enterobacteria, named ${\lambda}-bacteria$ isolated from fusiform fish, have strong anti-angiogenesis effect. ${\lambda}-28$ species bore higher anti-angiogenesis effect. Cultured liquid was performed salting out, dialysed and freezed dried. This sample was executed size exclusion chromatography with fraction collector. Anti-angiogenesis, cytotoxicity, and SDS-PAGE were carried out with fraction number. ${\lambda}-28$ species was lower toxicity against HUVECs and effective band was conformed with SDS-PAGE.

• JSTS:Journal of Semiconductor Technology and Science
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• v.17 no.1
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• pp.7-14
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• 2017

Due to the recent advances in Phage-Change Memory (PCM) technologies, a new memory hierarchy of computer systems with PCM is expected to appear. In this paper, we present a new page replacement policy that adopts PCM as a high speed swap device. As PCM has limited write endurance, our goal is to minimize the amount of data written to PCM. To do so, we defer the eviction of dirty pages in proportion to their dirtiness. However, excessive preservation of dirty pages in memory may deteriorate the page fault rate, especially when the memory capacity is not enough to accommodate full working-set pages. Thus, our policy monitors the current working-set size of the system, and controls the deferring level of dirty pages not to degrade the system performances. Simulation experiments show that the proposed policy reduces the write traffic to PCM by 160% without performance degradations.