• ETRI Journal
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• 제13권4호
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• pp.70-79
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• 1991

$In_1-x$$GA_X$$As_y$$P_1-y$ has a very wide range of applications in optoelectronic devices especially for optical communications because $In_1-x$$GA_X$$As_y$$P_1-y$ has the bandgap of the lowest dispersion ($1.3\mum$) and the lowest loss ( $1.55\mum$) of the optical fiber by changing the composition. The quality of $In_1-x$$GA_X$$As_y$$P_1-y$ epitaxial layer is believed to have a significant effect on the performance of device. The OMVPE growth conditions for the latticematched $In_1x$$GA_X$$As_y$$P_1-y$/InP were investigated. Effects of growth conditions such as V/III ratio, growth temperature, and Ga source material on the electrical and optical properties were studied. The composition, electrical and optical properities of $In_1-x$$GA_X$$As_y$$P_1-y$ were characterized using double crystal X-ray diffractometer (DCD), photoluminescence (PL), XPS(ESCA) and Hall measurement.

• 한국정밀공학회지
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• 제5권1호
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• pp.50-62
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• 1988

An experimental investigation of the machining characteristics of compact vermicular cast iron whose matrix were formulated under two kinds of annealing conditions has been conducted. The various characteristics of the machinability of CA cast iron depending upon its matrix and cutting condition have been obtained from the experiment. The results are as follow. As depth of cut increases, the shear stress slightly decreases in order $P_1, \P_2, \P_3$ which are classified by ferrite matrix of CV cast iron. As depth of cut increases, the normal stress increases, and annealing effect in heavy cutting is smaller than that in light cutting. The cutting energy slightly decreases, as depth of cut increases and the effect of annealing on cutting energy in light cutting is higher than that in heavy cutting. The cutting equation in this study are as follow. $P_1\:\2{\phi}\ + \1.49({\beta} - {\alpha} )=84^{\circ}$ $P_2\:\2{\phi}\ + \1.36({\beta} - {\alpha} )=82^{\circ}$ $P_3\:\2{\phi}\ + \1.34({\beta} - {\alpha} )=79^{\circ}$ Machining constants in this study for $P_1, P_2, P_3$give $74^{\circ} , 66^{\circ}, 61^{\circ}$ Tool wear increases as depth of cut increases, and decreases as ferrit matrix increases.

• 한국재료학회지
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• 제6권6호
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• pp.651-656
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• 1996

InGaAs/InGaAsP 다층박막을 corrugation이 형성된 InP 기판위에 MOVPE 방법을 이용하여 성장 시킨 후 성장조건에 따른 corrugation 높이의 변화와 석출상에 대하여 투과전자현미경을 이용하여 시킨 후 성장조건에 따른 corrugation 높이의 변화와 석출상에 대하여 투과전자현미경을 이용하여 연구하였다. Corrugation이 형성된 InP 기판을 PH3 및 AsH3가스를 동시에 공급해 주었는데 AsH3 가스의 압력이 높으면(1.8x10-2torr)많은 양의 As를 포함한 In1-xAsxP(x=0.3)석출상이 격자결함과 더불어 형성되었다. 반면에 AsH3 가스의 압력이 낮을때는 (1.0x10-3torr) corrugation의 높이가 30nm이었고, 적은 양의 As를 포함한 In1-xAsxP(x<0.1)석출상이 격자결함이 없이 형성되었다.

• 한국광학회:학술대회논문집
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• 한국광학회 1991년도 제6회 파동 및 레이저 학술발표회 Prodeedings of 6th Conference on Waves and Lasers
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• pp.135-138
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• 1991

A planar type PIN photodiode has been fabricated and discussed. We used OMVPE systems to grow the structure of u-InP/u-InP/n-InP. P-n junction was formed by Zn-diffusion method at 50$0^{\circ}C$, for 5 minitues. The device characteristics at 5V were as follows: Dark currents were distributed around 1nA. Capacitance was 1.6pF and responsivity was above 0.85 mA/mW for 1.3${\mu}{\textrm}{m}$ wavelength. Measured cut-off frequency(-3dB) at -5V was 1.1㎓.

• 원예과학기술지
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• 제35권3호
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• pp.289-299
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• 2017

The objective of this study was to determine the effect of replacing perlite (PL) with pellets processed with poultry feather fiber as an inert material to prepare growing medium. The growth and flowering of Salvia splendens 'Vista Red' grown in individual growing medium $Biosangto^{(R)}$, peat moss (PM), PL, and two pellets (P45-1 and P45-2) were evaluated. Peat moss was mixed with PL, P45-1, or P45-2 at various ratios (1:0 to 1:3 or 3:1 by volume) to investigate the feasibility of replacing PL with pellets. Nutrient composition of the growing medium and leaf tissues was analyzed. The number of florets, inflorescence length, plant height, and fresh weight of plants grown in media containing P45-1 or P45-2 were reduced compared to those grown in individual growing medium PM or PL. As the mixing ratio of P45-1 or P45-2 to PM was higher, the growth of salvia, such as inflorescence length, plant height, number of leaves, and fresh weight was inhibited. Our results indicate that mixing three parts PM with one part of P45-1 (PM/P45-1/3:1) or P45-2 (PM/P45-2/3:1) accelerated flowering and increased the number of florets and leaves compared to other mixing ratios of PM and pellets media. The concentrations of phosphorus (P), calcium (Ca), boron (B), iron (Fe), and copper (Cu) in individual growing medium PL, P45-1, and P45-2 were significantly lower than those in PM. The concentration of N was the highest in leaves of plants grown in P45-1 or P45-2 amended media, and the concentrations of P, Ca, and zinc (Zn) in leaves were lower in individual growing medium P45-1 or P45-2 than in PM and PL. The pH of PM/P45-1/3:1 or PM/P45-2/3:1 media was maintained at optimal level (5.8-5.9) and the concentrations of macro- and micro-elements in the media and leaves were considered to be optimal levels. Therefore, mixing three parts PM with one part P45-1(PM:P45-1/3:1) or P45-2 (PM:P45-2/3:1) is recommended for improved growth and flowering in salvia. This suggests that P45-1 or P45-2 can replace PL as an inert material to prepare growing medium.

• Biomolecules & Therapeutics
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• 제25권1호
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• pp.80-90
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• 2017

Initial discovery on sphingosine 1-phosphate (S1P) as an intracellular second messenger was faced unexpectedly with roles of S1P as a first messenger, which subsequently resulted in cloning of its G protein-coupled receptors, $S1P_{1-5}$. The molecular identification of S1P receptors opened up a new avenue for pathophysiological research on this lipid mediator. Cellular and molecular in vitro studies and in vivo studies on gene deficient mice have elucidated cellular signaling pathways and the pathophysiological meanings of S1P receptors. Another unexpected finding that fingolimod (FTY720) modulates S1P receptors accelerated drug discovery in this field. Fingolimod was approved as a first-in-class, orally active drug for relapsing multiple sclerosis in 2010, and its applications in other disease conditions are currently under clinical trials. In addition, more selective S1P receptor modulators with better pharmacokinetic profiles and fewer side effects are under development. Some of them are being clinically tested in the contexts of multiple sclerosis and other autoimmune and inflammatory disorders, such as, psoriasis, Crohn's disease, ulcerative colitis, polymyositis, dermatomyositis, liver failure, renal failure, acute stroke, and transplant rejection. In this review, the authors discuss the state of the art regarding the status of drug discovery efforts targeting S1P receptors and place emphasis on potential clinical applications.

• 대한전자공학회논문지
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• 제22권4호
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• pp.72-75
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• 1985

Double-heterostructure 구조의 1.3μm GalnAsP/lnP 웨이퍼를 LPE 기술로 성장시키고, 전면전극(broad contact)레이저 다이오드를 제작, 실온에서 펄스 발진시켜 전기적 및 광학적 특성을 조사하였다. 발진 개시전류는 2Amp. 이하, 발진개시전류밀도 3∼6 KAmp./㎠였으며, 파장 1.315μm에서 발진하는 것을 확인하였다.

• BMB Reports
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• 제55권9호
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• pp.447-452
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• 2022

Neurogenic differentiation 1 (NeuroD1) is an essential transcription factor for neuronal differentiation, maturation, and survival, and is associated with inflammation in lipopolysaccharide (LPS)-induced glial cells; however, the concrete mechanisms are still ambiguous. Therefore, we investigated whether NeuroD1-targeting miRNAs affect inflammation and neuronal apoptosis, as well as the underlying mechanism. First, we confirmed that miR-30a-5p and miR-153-3p, which target NeuroD1, reduced NeuroD1 expression in microglia and astrocytes. In LPS-induced microglia, miR-30a-5p and miR-153-3p suppressed pro-inflammatory cytokines, reactive oxygen species, the phosphorylation of c-Jun N-terminal kinase, extracellular-signal-regulated kinase (ERK), and p38, and the expression of cyclooxygenase and inducible nitric oxide synthase (iNOS) via the NF-κB pathway. Moreover, miR-30a-5p and miR-153-3p inhibited the expression of NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasomes, NLRP3, cleaved caspase-1, and IL-1β, which are involved in the innate immune response. In LPS-induced astrocytes, miR-30a-5p and miR-153-3p reduced ERK phosphorylation and iNOS expression via the STAT-3 pathway. Notably, miR-30a-5p exerted greater anti-inflammatory effects than miR-153-3p. Together, these results indicate that miR-30a-5p and miR-153-3p inhibit MAPK/NF-κB pathway in microglia as well as ERK/STAT-3 pathway in astrocytes to reduce LPS-induced neuronal apoptosis. This study highlights the importance of NeuroD1 in microglia and astrocytes neuroinflammation and suggests that it can be regulated by miR-30a-5p and miR-153-3p.

• 임산에너지
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• 제22권2호
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• pp.1-17
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• 2003

포플러는 생장이 빠르고 세대가 짧아 임목육종의 모델 수종으로 이용되어 왔을 뿐만 아니라 다른 어떤 수종보다 임목 육종성과가 많은 수종이다. 국내에서 개발된 신품종 포플러는 도입종으로 이태리포플러(p. eurmericana“I-214”,“I-476”), 이태리포플러 1, 2호(p. euramericana“Eco 28”, p. deltoides “Lux”), 교잡종으로 현사시 1, 2, 3, 4호(P. alba x p. glandulosa No. 1. 2. 3, 4), 양황철나무(P. nigra x P. maximowiczii), 수원포플러(P. koreana x P nigra var. italica) 등이 있으며, 신발육종으로 사시나무가 있다. 신품종으로 개발된 포플러류의 조림 실적은 지금까지 935,162 ha로 그 중 이태리포플러가 745,773ha, 현사시가 184,636 기타 신품종이 4,753ha가 조림되어 국토 녹화뿐만 아니라 농촌 경제에도 기여한 바 크다. 포플러와 관련되어 개발된 기술은 신품종 포플러의 적지판정, 교배가 불가능한 원연종간 교배, 무성증식법 등 수많은 기술을 개발 한 바 있다. 앞으로도 포플러는 용재수 및 가로수, 공원수 등 녹음수로서 뿐만 아니라 쓰레기 매립지 침출수, 축산폐수 등 각종 환경 오염물질 정화수로도 전망이 대단히 밝은 수종이다.

• 한국해양학회지
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• 제1권1_2호
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• pp.1-6
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• 1966

A latitudinal, differential pH distribution is observed in the Northeastern Pacific Ocean with a pH range of 8.15 at high latitude (42 N) to 8.29 at low latitude (23 N). These pH values are generally greater than the calculated equilibrium pH with respect to atmospheric carbon dioxide. If we assume that the calculated equilibrium pH values ae valid, then the surface waters are undersaturated with respect to the atmospheric carbon dioxide during April to June 1966. A high surface pH value of about 8.26 was observed immediately south of the SubarcticBoundary zone near 170 W. This value differs from the equilibration pH by as much as 0.1 unit.