• Journal of Microbiology and Biotechnology
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• v.26 no.7
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• pp.1224-1233
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• 2016

The present study assessed the effects of an aqueous extract of Acanthopanax koreanum root (AE) and of AE following fermentation by lactic acid bacteria (Lactobacillus plantarum and Bifidobacterium bifidum) (AEF) on human skin fibroblast HS68 cells exposed to ultraviolet B (UVB) irradiation and oxidative stress. AEF effectively antagonized the senescence-associated β-galactosidase staining and upregulation of p53 and p21^Cip1/WAF1 induced by UVB or H₂O₂ treatment in HS68 cells. It also exhibited excellent antioxidant activities in radical scavenging assays and reduced the intracellular level of reactive oxygen species induced by UVB or H₂O₂ treatment. The antioxidant and antisenescent activities of AEF were greater than those of nonfermented A. koreanum extract. AEF significantly repressed the UVB- or H₂O₂-induced activities of matrix metalloproteinase (MMP)-1 and -3, overexpression of MMP-1, and nuclear factor κB (NF-κB) activation. This repression of NF-κB activation and MMP-1 overexpression was attenuated by a mitogen-activated protein kinase activator, suggesting that this AEF activity was dependent on this signaling pathway. Taken together, these data indicated that AEF-mediated antioxidant and anti-photoaging activities may produce anti-wrinkle effects on human skin.

• The Korean Journal of Emergency Medical Services
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• v.25 no.1
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• pp.73-84
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• 2021

Purpose: The purpose of this study was to investigate the educational satisfaction of trainees in implementing violence prevention education by workers in the emergency room and insufficient education. Methods: The participants of the study were 65 emergency room employees in S area. Results: First, education was helpful if you actively participated in education, and if you did not actively participate in education, education was shown to be of little or no help (χ²(p)= .000 p-value<.05). Second, formal education (53.3%) was identified as the problem of preventive education currently in place of education, and statistics show that the biggest problem with applying emergency room violence prevention education at worksites is a lack of active support (41.7%) from the police and hospitals. Third, 48.3 percent of the respondents thought that the education methods invited experts were appropriate for emergency room violence prevention education. Conclusion: The problem with the current emergency room violence prevention education is that it is necessary to establish a connection program between hospitals and police stations and give lectures by experts in violence prevention education to apply the contents of the educational curriculum in the workplace with one time and formal education.

• Food Science of Animal Resources
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• v.43 no.1
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• pp.25-45
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• 2023

This study evaluated the antibacterial and antioxidant activities of ethanol extract of calamansi pulp (CPE) and its effect on quality and biogenic amine (BAs) formation in pork patties during storage. The CPE were prepared in various conditions (ethanol concentrations of 50%, 70%, and 90% with extraction periods of 3 and 6 days). The extract with potent antibacterial and antioxidant activities (90%, 6 days) was selected for addition to pork patties. Three groups were tested: Control (without extract addition), CPE addition at 0.2% w/w (0.2PCPE), and 0.4% w/w (0.4PCPE). The addition of CPE inhibited the formation of BAs, mainly cadaverine, histamine, and tyramine, in pork patties during storage. The pH and bacterial count of pork patties decreased significantly in a concentration-dependent manner following the addition of CPE. The instrumental color (CIE L^*, CIE a^*, and CIE b^*) tended to be higher in 0.4PCPE than in the control during storage. The thiobarbituric acid reactive substances and volatile basic nitrogen (VBN) values of pork patties were affected by CPE, showing a reduction toward lipid oxidation at any storage period, and maintaining the lowest VBN value in 0.4PCPE at the final storage day. Similarly, the reduction of total BAs in pork patties was observed ranged between 3.4%-38.1% under treatment with 0.2% CPE, whereas 18.4%-51.4% under 0.4% CPE addition, suggesting significant effect of CPE to improve meat quality. These novel findings demonstrate the efficacy of 0.4% CPE as a natural compound to preserve the quality and reduce BAs formation in pork patties during storage.

• Journal of Korean Academy of Nursing
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• v.53 no.2
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• pp.222-235
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• 2023

Purpose: The aim of this study was to identify the factors explaining protective behaviors against radiation exposure in perioperative nurses based on the theory of planned behavior. Methods: This was a cross-sectional study. A total of 229 perioperative nurses participated between October 3 and October 20, 2021. Data were analyzed using SPSS/WIN 23.0 and AMOS 23.0 software. The three exogenous variables (attitude toward radiation protective behaviors, subjective norm, and perceived behavioral control) and two endogenous variables (radiation protective intention and radiation protective behaviors) were surveyed. Results: The hypothetical model fit the data (χ²/df = 1.18, SRMR = .02, TLI = .98, CFI = .99, RMSEA = .03). Radiation protective intention (β = .24, p = .001) and attitude toward radiation protective behaviors (β = .32, p = .002) had direct effects on radiation protective behaviors. Subjective norm (β = .43, p = .002) and perceived behavior control (β = .24, p = .003) had direct effects on radiation protective intention, which explained 38.0% of the variance. Subjective norm (β = .10, p = .001) and perceived behavior control (β = .06, p = .002) had indirect effects via radiation protective intention on radiation protective behaviors. Attitude toward radiation protective behaviors, subjective norm, and perceived behavioral control were the significant factors explaining 49.0% of the variance in radiation protective behaviors. Conclusion: This study shows that the theory of planned behavior can be used to effectively predict radiation protective behaviors in perioperative nurses. Radiation safety guidelines or education programs to enhance perioperative nurses' protective behaviors should focus on radiation protective intention, attitude toward radiation protective behaviors, subjective norm, and perceived behavioral control.

• Journal of Korean Academy of Nursing
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• v.53 no.1
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• pp.129-143
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• 2023

Purpose: This study aimed to examine the mediating effects of clinical nurses' job crafting on organizational effectiveness based on the job demands-resources model proposed by Bakker and Demerouti (2017). Methods: The participants consisted of 393 nurses working in nursing units of a tertiary general hospital located in Cheongju region. The data, collected using questionnaire from August 9 to August 20, 2021, were analyzed using SPSS 23.0 and AMOS 27.0. Results: The goodness-of-fit (GoF) test results on the modified model (χ² = 2.7, GFI = .94, SRMR = .03, RMSEA = .06, NFI = .92, CFI = .94, TLI = .92, AGFI = .90), indicated that the GoF index satisfied the recommended level. Regarding the effects of each variable on organizational effectiveness, job crafting showed statistically significant direct (β = .48, p < .001), indirect (β = .23, p < .001), and total effects (β = .71, p < .001). Burnout showed statistically significant direct effect (β = - .17, p < .001). Work engagement showed statistically significant direct (β = .41, p < .001) and total effects (β = .41, p < .001). The factors explaining organizational effectiveness were job crafting, burnout, and work engagement, which had an explanatory power of 76.7%. Conclusion: Nurses' job crafting is an important mediating factor for enhancing the organizational effectiveness of nursing organizations. Hospitals should develop job-crafting success cases and related education and training programs as a strategy for enhancing the job crafting of nurses and, consequently organizational effectiveness.

• Korean Circulation Journal
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• v.53 no.12
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• pp.843-854
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• 2023

Background and Objectives: We evaluated the effect of diabetes on the relationship between body mass index (BMI) and clinical outcomes in patients following percutaneous coronary intervention (PCI) with drug-eluting stent implantation. Methods: A total of 6,688 patients who underwent PCI were selected from five different registries led by Korean Multicenter Angioplasty Team. They were categorized according to their BMI into the following groups: underweight (<18.5 kg/m²), normal weight (18.5-24.9 kg/m²), overweight to obese (≥25.0 kg/m²). Major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of death, nonfatal myocardial infarction, stroke, and target-vessel revascularization, were compared according to the BMI categories (underweight, normal and overweight to obese group) and diabetic status. All subjects completed 1-year follow-up. Results: Among the 6,688 patients, 2,561 (38%) had diabetes. The underweight group compared to normal weight group had higher 1-year MACCE rate in both non-diabetic (adjusted hazard ratio [HR], 2.24; 95% confidence interval [CI], 1.04-4.84; p=0.039) and diabetic patients (adjusted HR, 2.86; 95% CI, 1.61-5.07; p<0.001). The overweight to obese group had a lower MACCE rate than the normal weight group in diabetic patients (adjusted HR, 0.67 [0.49-0.93]) but not in non-diabetic patients (adjusted HR, 1.06 [0.77-1.46]), with a significant interaction (p-interaction=0.025). Conclusions: Between the underweight and normal weight groups, the association between the BMI and clinical outcomes was consistent regardless of the presence of diabetes. However, better outcomes in overweight to obese over normal weight were observed only in diabetic patients. These results suggest that the association between BMI and clinical outcomes may differ according to the diabetic status.

• Korean Journal of Ecology and Environment
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• v.53 no.2
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• pp.148-155
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• 2020

In this study, we analyzed the effects of the presence or absence of weirs on fish assemblages in wadeable streams (Stream order 1^st~4^th). More specifically, we investigated these effects by evaluating the differences in stream size. The results showed differences in the fish assemblages in third or higher order streams (PERMANOVA, P<0.005). The presence or absence of weirs mainly affected variables such as the number of species the individuals, and species richness index, whereas no difference was observed in the populations of exotic, endemic, and endangered species. A SIMPER analysis showed that the common species Zacco platypus, Zacco koreanus, and Pungtungia herzi are dominant in their corresponding streams (contribution>5%), and that these are the main contributors to differences among the fish assemblages. All these species showed high relative abundances at the sites with weirs. Altered environments by the presence of weirs provided these species with concentrated habitats. In summary, this study analyzed the effects of weirs on fish assemblages on a broad, nationwide, scale, and these results can effectively aid future studies on the specific effects of weirs.

• Korean Journal of Environmental Biology
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• v.39 no.2
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• pp.218-224
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• 2021

This study was conducted to determine the mass-loss rates and the changes in carbon/nitrogen (C/N) ratio of dead woods, which were of following species: Dryobalanops aromatic, D. rappa, and Cratoxylum arborescens. These were dominant tree species in mixed Dipterocarp forests (MDF) and peat swamp forests (PSF) in Brunei Darussalam. In May, 2019, 48 dead wood samples (15 cm×4.8 cm×5 cm) were placed in MDF and PSF sites, and all the samples were collected after 16 months. The effects of species on mass loss were statistically significant (p<0.05); however, no difference was observed in the mass loss obtained from the two forest types (p>0.05). The initial density (g·cm^-3) of the dead woods D. aromatic, D. rappa, and C. arborescens, was 0.64±0.02, 0.60±0.00, and 0.44±0.01, respectively. Also the annual mass loss rate (%) was estimated to be 6.37, 8.17, and 18.53 for D. aromatic, D. rappa, and C. arborescens, respectively. The proportion of dead woods in decay class III was only 25% of C. arborescens samples, which were attacked by wood-feeding invertebrates, such as termites. The C/N ratio decreased significantly in D. aromatic and D. rappa, but the decreasing trend of C/N ratio was not statistically significant in C. arborescens. The results indicate that physical traits of dead woods, such as density, could be one of the main factors causing the decomposition of dead woods initially, as invertebrates such as termites are one of the key decomposers of dead wood in tropical rainforests. In the samples of C. arborescens, which was attacked by invertebrates, nitrogen immobilization occurred to lesser extent as compared to that observed in D. aromatic and D. rappa.

• Journal of Practical Agriculture & Fisheries Research
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• v.25 no.4
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• pp.53-59
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• 2024

The purpose of the study was to examine the effects of initial body weight and synbiotics supplementation in the diet on growth performance of weaned pigs. A total of 80 crossbred pigs (Landrace×Yorkshire×Duroc, d 28±3, body weight 6.40±1.70 kg) were randomly distributed 4 treatments (4 replication, 5 pigs/replication). The treatments were 1) high initial body weight group (PC), 2) low initional body weight group (NC), 3) low initial body weight with 0.2% antibiotics (amoxicillin) supplementaion group (AB), 4) low initial body weight with 0.2% synbiotics (AllTech^® Bio-Mos 0.3%, 0.3%, Bacillus subtillis 0.1%, formic acid 0.1%) supplementation group (Syn). AllTech^® Bio-Mos is consist of at least 25% of glucomannanprotein extracted from the cell wall of Saccaromycess cerevisae. Growth performance was measured during 28 d. Average daily gain (ADG) of AB and Syn groups were significantly (p<0.05) higher than that of NC group. However, final body weight at the end of experiment were not different among NC, AB, and Syn groups. Initial body weight and final body weight of PC group were statistically (p<0.001) higher compared to those of other groups. Additionally, PC showed the tendency of lower average daily feed intake and higher ADG, thereby lower feed conversion ratio compared with other groups. Therefore, the current results imply that supplementation of antibiotics and synbiotics in diets for weaned pigs could not catch up with significant differences in initial body weight.

• Journal of the Korean Orthopaedic Association
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• v.56 no.3
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• pp.208-214
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• 2021

Purpose: Verifying a reliable predictor of the progression of vertebral deformity in patients with acute osteoporotic fractures of the lumbar spine may be useful. A qualitative analysis of the muscle near the spine was performed using magnetic resonance imaging (MRI), and its correlation with a spinal deformity was determined under the hypothesis that the causes of the kyphotic deformity are associated with muscle reduction in the multifidus and erector spinae. Materials and Methods: The study was performed in a retrospective manner using the electronic medical records of patients who presented to the author's institution between January 2007 and March 2018, and were diagnosed with an acute lumbar fracture. The fat infiltration rates of the multifidus and erector spinae were measured using MRI taken at the time of injury, and the mean value was defined as the total fat infiltration rate (TFI). Based on lateral radiographs of the lumbar spine at the one-year follow-up, the loss of height of the vertebral body, the kyphotic angle and the wedge angle were measured. The statistical significance was confirmed by calculating the Pearson correlation coefficient. Results: One hundred twenty-nine patients, of which 30 were male and 99 were female, were examined. The mean age was 71.28 years. The mean T-score was -3.53±0.79 g/cm², and the mean fat infiltration was 15.20%±11.99%. TFI was positively correlated with age (R=0.373, p<0.001), compression rate (R=0.369, p<0.001), and Cobb's angle (R=0.386, p<0.001) after a one year follow-up, but negatively correlated with the BMD score (R=-0.252, p=0.004). As the fracture progressed to the lower lumbar level, the compression rate (R=-0191, p=0.030) and wedge angle (R=-0.428, p<0.001) at the time of injury tended to decrease. Conclusion: In patients with osteoporotic vertebral fractures, the fat infiltration rate may be an important predictor of conservative treatment. The prognosis of patients with a high-fat infiltration rate should be explained during patient education, and the patients must be monitored closely through short-term outpatient follow-up.