• Journal of Physiology & Pathology in Korean Medicine
• /
• v.30 no.6
• /
• pp.370-375
• /
• 2016

Recent advances in systems biology are shedding a new light on the traditional medicine research. The systems biology highlights the way each component interacts with each other within a system, and the network behavior that emerges from such interactions. This feature of systems biology can accent the systemic aspects of Korean medicine such as the mechanism of action of herbal formulae, pattern differentiation, and the meridian systems, as both the Korean medicine and the systems biology theorize the human physiological functions and phenomena from a holistic point of view. This paper outlines the meaning of the recent Korean medicine research using the systems biology methodology. We discuss the methodologies of the two fields in a comparative manner, and overview the advantages and limitations of the integrated approaches. Finally, we suggest the future prospects for the systems biology inspired approaches to the Korean medicine research. The systems biology may provide a new modernized research methodology for the Korean medicine that can highlight its unique features.

• The Journal of Pediatrics of Korean Medicine
• /
• v.35 no.4
• /
• pp.82-95
• /
• 2021

Objectives The purpose of this study is to analyze clinical studies on the effectiveness of TCM (traditional Chinese medicine) for pompholyx treatment and provide evidence for Korean medicine use. Methods Randomized controlled trials (RCT) which used TCM as a treatment for pompholyx were searched in China National Infrastructure (CNKI) platform. The risk of bias of studies was assessed by using Cochrane risk of bias (RoB) 2.0 tool. Results The selected 10 RCTs showed that the experimental group treated with either TCM alone or with a combination of TCM and Western medicine showed more significant therapeutic effect compared to the control group which Western medicine alone. Conclusions Based on the studies from China, TCM may be an effective treatment for pompholyx. This provides evidence for Korean medicine use, and its possible effectiveness in treating pompholyx

• Korean Journal of Oriental Medicine
• /
• v.15 no.1
• /
• pp.49-54
• /
• 2009

Objectives : The study aims at assessing information on cultural festivals of Korean medicine. Method : We investigated data about the National Festival collected from asking the Ministry of Culture, Sports and Tourism, Efestival of YonhapNews, Driving Korea of KBS and JOINS. Result : Since the 1990s, cultural festivals of Korean medicine are increased. The festival of the ginseng was the most. 5 cultural festivals held on The Chungcheongnam-do are the best in cultural festivals of Korean medicine. 65% of cultural festivals was held in the fall. In the budget of the cultural festivals in Korean medicine, the most were 1~5 hundred million won. Conclusions : We wish to propose a model for developing cultural semiology and visual literacy, with the Korean medicine. Subsequently, it is expected that such a model can underpin the importance of developing coherent edutainment content while illustrating the true meaning/value of local festivals.

• The Journal of Internal Korean Medicine
• /
• v.25 no.4
• /
• pp.200-206
• /
• 2004

Anterior inferior cerebellar artery(AICA) is a branch of the basilar artery which supplies the bloods for ventrolateral cerebellum and the lateral tegmentum of the lower two-thirds of pons. AICA occlusion can cause such symptoms as acute-onset unilateral deafness, vertigo, facial weakness and ataxia. A case of sudden hearing loss, facial palsy and vertigo caused by AICA territory infarction recently presented itself. Korean Oriental and Western medical therapy were applied in combination. Facial palsy and vertigo improved, but hearing loss did not improve. This case is reported with a brief overview of related literatures.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.30 no.2
• /
• pp.71-80
• /
• 2017

Objectives: The purpose of this systematic review was to overview and evaluate the effectiveness of acupoint catgut embedding for climacteric hot flush. Methods: We searched articles from CNKI, Pubmed CENTRAL, Koreantk, Oasis online databases. After searching the articles, we performed quality assessment using Cochrane risk of bias (RoB) tools. Results: Among the 20 articles were searched, one radomized controlled clinical trial (RCT) was selected. 1 Study showed that Acupoint catgut embedding treatment has significant effect on climacteric hot flush in terms of the effectiveness rate. Conclusions: This study found encouraging but limited evidence of aupoint catgut embedding theragpy for climacteric hot flush.

• Journal of Acupuncture Research
• /
• v.30 no.4
• /
• pp.151-159
• /
• 2013

Objectives : The purpose of this systematic review was to overview and evaluate the current state of the usage of bee venom acupuncture. Methods : We collected 173 articles on bee venom acupuncture(BVA) clinical study from eight electronic databases from January 2002 to June 2013. Results : BVA was used in musculoskeletal diseases for 66 %, and the chosen acupoints were various. The ratio of the reports which had collected below 10 cases was 43 %. The concomitant treatment and evaluation tools showed diversity in each article. Conclusions : Bee venom clinical study shows the lack of unity and consistent regulation, and has low clinical cases. Future studies should correct these limits and promote more varied research to develop the therapy of bee venom acupuncture.

• Journal of Acupuncture Research
• /
• v.31 no.3
• /
• pp.35-43
• /
• 2014

Objectives : The purpose of this review is to overview and evaluate the current state of the usage of acupotomy. Methods : Eight electronic databases(Science direct, Pubmed, five Korean databases, CKNI) were searched for relevant articles and data from January 1999 to May 2014. Results : Thirty-nine articles were included. Acupotomy were used in musculoskeletal diseases(n=34) and other diseases(n=5). Among musculoskeletal diseases, lumbar spine(n=12) neck(n=5) and shoulder(n=3) diseases were mostly often used. Most studies(n=21) had small sample size(under 10 people) and combined with other therapies(acupuncture, herbal medicine, physical therapy, etc.). Conclusion : Acupotomy appears to be effective and useful for musculoskeletal diseases and some other diseases. But there were a few clinical studies for acupotomy and had many limitations to judge its effectiveness. Further modified studies are required.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.25 no.5
• /
• pp.894-899
• /
• 2011

Traditional Korean Medicine (TKM) has been actively researched through various approaches, including computational methods. This paper aims at providing an overview of domestic studies using the computational techniques in TKM field. A literature search was conducted in Korean publications using OASIS system, and major studies of data mining in TKM were identified. A review was presented in six diagnosis fields, including sasang constitution diagnosis, eight constitution diagnosis, tongue diagnosis, pattern diagnosis for stroke, diagnosis based on ontology, diagnosis for cause of disease. They collect clinical data themselves for experiments and primarily applied a algorithm of decision tree, SVM, neural network, case-based reasoning, ontology reasoning, discriminant analysis. In the future, there needs to identify which algorithm is suitable to diagnosis or other fields of TKM.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.25 no.6
• /
• pp.1056-1060
• /
• 2011

To summarize and make a reference number of natural materials used to treat diabetic peripheral neuropathy. We surveyed all papers of diabetic peripheral neuropathy studies using natural materials in PubMed as "diabetic peripheral neuropathy AND plant", "diabetic peripheral neuropathy AND herbal", "diabetic peripheral neuropathy AND herb", etc. The number of papers, the formation of experiments, frequency of natural materials studies, and main studies were analyzed. Total 48 studies were finally selected. Of the papers, experiments with rats were the most common. Most studies were about fatty acids or herbal medicines. Rehmannia glutinosa, Cinnamomi Ramulus, Astragali Radix and so on were relatively studied much. This study produced an overview of worldwide natural materials used for diabetic peripheral neuropathy. This result may provide a valuable information of development of Korean herbal medicine used to treat diabetic peripheral neuropathy.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.30 no.6
• /
• pp.397-401
• /
• 2016

The quality control is a fundamental procedure for the standardization of herbal medicine to guarantee the consistency of efficacy and safety. For a long time, the quality analysis of herbal medicine has been largely dependent on the routine sensory evaluation, such as taste, smell, color, and shape. However, with the recent development of analytical instruments, various scientific approaches have been introduced in this field. On the basis of the theory that the biological activities of herbal medicine are mainly contributed by its chemical compositions, several types of chemical markers have been suggested for the quality evaluation. In addition to the analytical methods for the specific marker compound(s), including analytical marker and active marker, recently, chemical fingerprinting, a method comparing the chromatographic pattern of the whole chemical components, has been developed and widely accepted as a reliable approach for the quality control of herbal medicine. Moreover, in order to exactly understand the relationship between complex compounds and their holistic biological activities in herbal medicine, unique strategies, such as "BECCs (bioactive equivalent combinatorial components)" and "PhytomicsQC" have been established. In this article, we give an overview of the several categories of chemical markers and the recent research trends for the quality evaluation of herbal medicine.