• Journal of Society of Preventive Korean Medicine
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• v.11 no.2
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• pp.87-99
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• 2007

Background : Most traditional Korean doctors use "Packed Herbal Medicine", which is made from boiling various herbs together. However, the current insurance system doesn't cover the act of making packed herbal medicine. Therefore it is urgent for these doctors to study and find the best and most logical insurance program to cover the Packed Herbal Medicine system. Objectives : The purposes of this study were to investigate whether Announced System of Herb Price is proper for stability of medical herbs's price. Methods : This study made these following results by studying medical herbs's price of KOMD(The korea oriental medicine distribution company) from 2004 March to 2007 March The results are summarized as follows ; The 50 most frequently used herbs were chosen from the 831 standard prescriptions according to 26 pre-determined specific diseases. These prescriptions are considered the most important for this study and insurance purposes. fluctuations of fifty medical herbs which were used much about a predetermined list of 831 prescriptions are multiple function not linear equation. fluctuations of fifty medical herbs which were used much about a predetermined list of 831 prescriptions are different according to time. Therefore, to notify medical herbs's price is valid method for stability of medical herbs's price.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.3
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• pp.367-372
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• 2010

The purpose of this study is to make a basis of in vivo or clinical study about alopecia. We investigated the prescriptions of alopecia by researching oriental medicine literature. We found the prescriptions used for alopecia. And we surveyed the frequency and classification of the herbs used for alopecia. The results of this study were recorded as follows. The most frequently used single herbs in the prescriptions were Angelicae Gigantis Radix(當歸), Glycyrrhizae Radix(甘草), Poria(茯笭), Paeoniae Radix Alba(白芍藥). Herbs specifically frequently used in the prescriptions of alopecia were as follows. Polygoni Multiflori Radix(何首烏), Rehmanniae Radix(生地黃), Cuscutae Semen(菟絲子), Bupleuri Radix(柴胡), Scutellariae Radix(黃芩), Viticis Fructus(蔓荊子), Aconiti Iateralis Preparata Radix(附子). Herbs frequently used were classified by property. The result was as follows. (()-The number of herbs) 補益藥(32), 解表藥(18), 淸熱藥(15) 收澀藥(9), 活血祛瘀藥(8), 利水滲濕藥(8).

• Journal of the East Asian Society of Dietary Life
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• v.18 no.2
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• pp.234-241
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• 2008

The purpose of this study was to evaluate antioxidant effects of oriental herbs in the pork meat Wanja(0.5${\times}$5 cm, 20 g) baked at 180$^{\circ}C$ for 5 min and reheated 30 see in microwave oven after storage at 4$^{\circ}C$ for 4 days. The moderate amount of freeze dried powder of oriental herbs included in Wanja were 1.0% in CN(Cinnamomum lureitri Nees), 0.5% in AS(Acanthopanax sessiliflorus Seed), and in AN(Angelica gigas Nakai), respectively. In sensory evaluation, the Wanja added with AS was the most preferred significantly. The Wanja without oriental herbs was the least preferred because of its the highest level in off-flavor. During storage at 4$^{\circ}C$ in the refrigerator for 10 days, the Wanja without oriental herbs was increased rapidly in acid value after 6 days, but the Wanja made with 1.0% CN powder was increased after 8 days, and with 0.5% AS and 0.5% AN were after 10 days. The Peroxide value of Wanja without oriental herbs was increased to unedible level after 8 days. But those of Wanjas made with CN, with AS, and with AN were increased to low level enough to eat till 10 days. The result in peroxide value between of Wanjas with and without oriental herbs was the same tendency in TBA value.

• The Journal of Internal Korean Medicine
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• v.30 no.1
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• pp.64-73
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• 2009

Objectives : Consumption of fermented foods has been known to alleviate some of the symptoms of atopy and may limit allergy development, while there are also many medicinal herbs proved to be effective for immunologically-mediated diseases. In this study, we introduced modern zymology to ferment some herbs to see if fermentation has the possibility of increasing the anti-inflammatory effects of medicinal herbs. Interleukin-4 (IL-4) and interferon-gamma $(INF-\gamma)$ have been demonstrated to be the main factors in the pathology of allergic diseases. Methods : We measured the levels of IL-4 and $INF-\gamma$ on concanavalin A-induced BALB/c mice spleen cells, which were subsequently treated with fermented and unfermented herbs. We then compared the fermented groups with unfermented groups to see if the anti-inflammatory effects of the herbs were influenced by fermentation. Results and Conclusions : Our results showed that fermentation had the potential to increase the anti-inflammatory effects of some medicinal herbs, and Astragalus membranaceus and Salvia miltiorrhiza would be the most suitable medicinal herbs for fermentation among the herbs in this study.

• Journal of Oriental Neuropsychiatry
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• v.17 no.2
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• pp.37-59
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• 2006

Objective : This study was designed to asses the effect of Hwangryunhaedoktang and herbs on Mouse neuroblastoma 2a cells damaged by hypoxia-reoxygenation. Method : Mouse neuroblastoma 2a (N2a) cells were measured by MTT assay and LDH assay after 48h hypoxia and 6h reoxygenation. Mouse neuroblastoma 2a (N2a) cells were treated by Hwangryunhaedoktang and herbs. Result : 1. Hwangryunhaedoktang was effective on LDH assay of hypoxia and reoxygenation. 2. All of herbs were generally effective on LDH assay of hypoxia and reoxygenation. In LDH assay of hypoxia, the effects of herbs depended on concentration. In MTT assay of hypoxia, Coptidis Rhizoma and Gardeniae Fructus were effective. In MTT assay of reoxygenation most of herbs were not effective. But Phellodendri Cortex was effective in high concentration. Conclusion : The results imply that Hwangryunhaedoktang and all herbs of it nay have protective effect on dementia and aging.

• Journal of Oriental Neuropsychiatry
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• v.16 no.1
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• pp.19-41
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• 2005

Object : This study was designed to asses the effect of Sunghyangjungkisan-ga-pogongng and herbs on Mouse neuroblastoma 2a cells damaged by hypoxia-reoxygenation. Method : Mouse neuroblastoma 2a (N2a) cells were measured by MTT assay and LDH assay after 48h hypoxia and 6h reoxygenation, Mouse neuroblastoma 2a (N2a) cells were treated by SHJG+P and herbs. Result : 1. SHJG+P was effective on LDH assay of hypoxia and reoxygenation. 2. The herbs were generally effective on LDH assay of hypoxia and reoxygenation. In MTT assay of hypoxia JP and GC were effecctive. In LDH assay of hypoxia all of herbs were effective. DMH, BC, SY, NS were more effective than other herbs. In LDH assay of reoxygenation KH, BH, BBR, DMH were especially effective. In MTT assay of reoxygenation most of herbs were not effective. But GC, SY, BH, JP were effective. Conclusion : The results imply that SHJG+P and all of berbs may have protective effect on dementia and GC, SY, BH, JP may have protective effect.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.3
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• pp.90-98
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• 2008

Purpose: Menopausal syndrome is caused by urgent changes of sex hormone in women. The hormonal therapy can soothe the problems of menopausal patients, but it can increase the probability of another disease, such as breast cancer, heart attack, etc. So the demand of alternative herb therapy is increasing in Western countries. In Korea, herbal medicine is imported and used by Western doctors. To know and use the alternative herbal medicine, Korean Medical doctors should know their efficacy and safety. Methods: We researched the Medline(Pubmed) with the key word such as 'CAM', 'herb' and 'menopause'. We selected the herbs known as treating the menopausal syndrome and researched the similar or same herbs that are used in Korean medicine by the scientific name and efficient ingredients. To evaluate the efficacy of the herbs, we compared the herbs that were differently defined in alternative and Korean medicine Results: Balm, black cohosh, chaste berry, dong quai. evening primrose oil. ginkgo, St. John's wort, valerian root, and sarsaparilla were chosen as prevalent herbs used in alternative medicine. The pharmacologic effect of Black cohosh, licorice root, St. John's wort were recognized. But these three herbs are not usually prescripted for menopausal patients in Korean medicine. So we could apply these three herbs as one of Korean medical treatments. The efficacy of other herbs cannot be surely prescripted for menopausal patients. Conclusion: The efficacy and safety of alternative medicine is not proved yet. But to diversify the treatmental methods of Korean medicine, we need to prove and use these medicine as one of Korean medical treatment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.4
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• pp.566-571
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• 2012

The purpose of this study was to assess the effects of herbs aroma on relaxation in highly stressed volunteers with heart rate variability(HRV) and SACL(stress arousal check list). 28 highly stressed volunteers participated in this study. The volunteers were examined with heart rate variability(HRV) and SACL(stress arousal check list) before and after smell herbs aroma. After smelling powder incense composed with oriental medicine herbs, mean RR, SDNN, LF, HF, TP were incresed and mean HRV, LF/HF ratio were decreased, but it was not significant. And VLF, norm HF were incresed and norm LF was decreased significantly. This results show that the powder incense composed with oriental medicine herbs effects on decresing sympathetic nervous activity and increasing parasympathetic activity and rebalancing autonomic nervous system who were under stress.

• The Journal of Korean Medicine
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• v.21 no.2
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• pp.43-51
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• 2000

Objectives : It is well known that vegetables and fruits contain minerals, including potassium, sodium and phosphorus etc. Though most oriental herbal medications are made of natural plants, western scientists suppose that they also contain certain amounts of minerals and so are injurious to kidney disease such as chronic renal disease. However, by the reason of the limitation of western medical treatment on kidney disease, many patients depend on oriental medical treatment, which includes taking oriental herbal medicine. So, in order to find out the mineral contents in oriental herbal medicine, and to establish the oriental herbal medication's safety in kidney disease, studies were performed. Methods : In this study, we analyzed 42 oriental herbs commonly used in kidney disease by the Inductively Coupled Plasma(ICP) method. Results : 1. The potassium and sodium contents of oriental herbs were 3-10 times as much as of food. 2. The mineral contents of a daily dose of oriental herbal medicine satisfied the restriction of dietary mineral in CRF, though the amount of mineral intakes by food was considered. Conclusions : The mineral contents of oriental herbal medicine are less than the limits of mineral restriction in renal failure. The yielded results, we carefully suggest that oriental herbal medicine does not induce accumulation of minerals or damage in kidney disease patients.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.64-64
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• 2003

It is thought that highly reactive oxygen radicals generated at the ischemia-reperfusion in case of strokes play an important role in damaging the brain. We examined the neuroprotective effects from the several medicinal herbs in the transient ischemic rat model and compared their effects with the free radical scavenging activities. Transient ischemia was induced by intraluminal occusion of the right middle cerebral artety for 120 min and reperfusion was continued for 22 h in rats. The free radical scavenging properties of medicinal herbs were examined in vitro by determination of the interaction with the 1,l-diphenyl-2-picrylhydrazyl (DPPH) stable free radical. Aqueous extracts of 11 medicinal herbs (200 mg/kg) were orally administered, promptly prior to reperfusion and 2 h after reperfusion. Total infarction volume in the ipsilateral hemisphere of ischemia reperfusion rats was significantly lowered by the treatment of 7 medicinal herbs (Sophora flavescens, Lycopus lucidus, Sanguisorba officinalis, Caesalpinia sappan, Albizia julibrissin, Rubia akane, Psoralea corylifolia, Prunella vulgaris). However, all of these medicinal herbs did not show antioxidative activities. These results suggest that neuroprotective effects of several drugs are not always correlated with their antioxidative properties.