• Journal of Advanced Navigation Technology
• /
• v.20 no.5
• /
• pp.446-452
• /
• 2016

The aircraft has to be considered for safety very importantly because of peculiarity of flight in the air, so it should be retained through proper inspection and maintenance not only in production phase but also in operating phase. Recently, it is using the latest technology as engineering approach not depending on human factor to determine on maintenance needs, and domestic production rotary aircraft also has the health & usage monitoring system to measure and to monitor major components. However, continued vibration exceedance phenomenon occurred in production and operation phase because of inappropriate thresholds, and it confirmed as false alarm which is not necessary to repair. In this paper, it is described that operational concept of HUMS, and especially it contains a study result for efficiency of aircraft operation and ultimately the improvement of flight safety by optimizing HUMS thresholds to determine efficiently necessity of maintenance under limited conditions and by establishing inspection/maintenance procedures when the re-designated thresholds exceedance occurred.

• Asian-Australasian Journal of Animal Sciences
• /
• v.24 no.10
• /
• pp.1473-1482
• /
• 2011

Adult male musk deer (Moschus spp.) secrete musk, a widely used ingredient in traditional Asian medicine and the international perfume industry. Musk deer are endangered due to historic over-utilization of musk and habitat loss. Musk deer farming, provides an important way of conserving musk deer and ensuring a sustainable musk supply. For over 50 years musk deer farming has been conducted in China with the endangered Alpine musk deer (Moschus sifanicus) the predominant farmed musk deer species. To date, few studies have examined the musk production of captive musk deer. This study analyzed musk-extraction data collected from 1997 to 2009 at Xinglongshan Musk Deer Farm, Gansu, China. The musk-extraction ratio (MER) of captive male musk deer was 90.30% (n = 732), while the annual average musk extraction (AME) per animal was $7.90{\pm}0.17\;g$ with the range from 0.00 g to 34.20 g (n = 732). The origin of the deer had an influence on AME and MER production, with male wild-captured (WC) individuals recording higher values (AME, $8.76{\pm}0.27\;g$, n = 272; MER, 93.75%, n = 272) than those of captive breeding (CB) males (AME: $7.39{\pm}0.22\;g$, n = 460; MER: 88.26%, n = 460). The origin of an individual's parents, however, did not influence AME and MER. Age also influenced musk production with the MER of 1.5-year-old males being 87.5% with an average musk production of $8.27{\pm}0.47\;g$ (n = 96). The peak period for musk production was from 1.5 to 8.5 years of age. The results of our study demonstrate musk deer farming could work as an effective measure to protect musk deer and provide sustainable musk resources, however, the musk production including MER and AME could be improved through optimizing the managing and breeding system in endangered musk deer farming.

• Microbiology and Biotechnology Letters
• /
• v.45 no.2
• /
• pp.149-154
• /
• 2017

To increase the efficiency of esterase production by Bacillus, high cell-density culture of recombinant Escherichia coli through fed batch fermentation was tested. Cells were cultured to $OD_{600}$ of 76 (35.8 g/l DCW) with dissolved oxygen level controlled to least above 30% air saturation by supplying pure oxygen. Cells were cultured to an $OD_{600}$ of 90 (42.4 g/l DCW) with glucose feeding controlled to at least 1 g/l. However, the cells reached stationary phase at the late stage of culture, despite glucose being supplied. Cells were cultured to an $OD_{600}$ of 185 (87.3 g/l DCW) by supplying additional medium with fortified yeast extract. To increase the productivity of the recombinant protein, cell growth and esterase productivity based on induction time were evaluated. Late exponential phase induction for esterase production in fed batch fermentation resulted in maximum optical density $OD_{600}$ of 190 (89 g/l DCW) and maximum esterase activity of 1745 U/l, corresponding to a 5.8-fold enhancement in esterase production, compared to the early exponential phase induction. In this study, we established fermentation methods for achieving maximum production of Bacillus-derived esterase by optimizing IPTG induction time in high-cell density culture by supplying pure oxygen and a nitrogen source.

• Journal of Korean Ophthalmic Optics Society
• /
• v.18 no.4
• /
• pp.509-517
• /
• 2013

Purpose: The purpose of this study is developing the 2.6 ${\times}$ optical scope with a Abbe-K$\ddot{o}$nig prism. Methods: First, considering the size of the effective aperture and the focal length of the objective lens, we designed an Abbe-K$\ddot{o}$nig prism. Next, we calculated the optical and geometric distances of Abbe-K$\ddot{o}$nig prism designed in this way. After allocating the focal length of the objective lens and the eyepiece lens so as to satisfy the magnification and optical effective distance of the entire system by using this calculation result, we completed the entire system by optimizing this optical system. Results: We were able to complete the optical scope of about 2.6 ${\times}$ magnification by designing an objective lens with a focal length of 63.13 mm which was composed of two pieces, an eyepiece with a focal length of 24.3 mm which was composed of four pieces, and an Abbe-K$\ddot{o}$nig prism with a face length 11.5 mm. Conclusions: We designed and fabricated an optical scope with 2.6 ${\times}$ magnification employing an Abbe-K$\ddot{o}$nig prism. Then, this system became the compacted optical system with a barrel diameter of 31 mm, characterized by an effective aperture of 12.0 mm and an effective optical barrel length of 103 mm and a resolution of 200 cycles/rad at 50% MTF criterion within the half viewing field angle of $6.42^{\circ}$.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.6
• /
• pp.3448-3454
• /
• 2014

Generally existing structure analysis was applied to elastic analysis basically in practice. Considering the nonlinear material and the nonlinear geometric to be a more precise analysis, for this reason, The necessity for a structual analysis have been constantly required. Therefore, after optimization is performed, designed a simple model which is applied the principle of nonlinear in this study, a structural analysis of existing experienced users, have a aims at presenting theory and a method in order to perform anyone the analysis easily. In this study, the proposed model applied to die ribs, Regarding the shear load, less strain and stress was generated but strength was sufficient. The initial strain and stress was reconfigured to fit the size and shape, A hyperstudy in conjunction with Abaqus with nonlinear structural analysis, revealed an acceptable maximum and minimum range of stress and under the conditions of minimum strain, the plate made with a constant increment. In the experimental models, the plate thickness was given a power of 40 Newton, according to the thickness of the press die through an iterative process. When the stress and strain was applied to the die thickness, 7-8mm thickness could be obtained by optimizing.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.1
• /
• pp.506-512
• /
• 2017

The purpose of this study was to improve release rate and bioavailability of nateglinide formulation. Polymorphism selection and particle size control were performed to enhance formulation dissolution rate, and a pH modifier was included in the formulation to overcome pH-dependent solubility of nateglinide. The enhanced dissolution rate was characterized by using a dissolution test. The results showed that H-type raw material had a higher dissolution rate than that of B-type raw material. There was 6.2% difference in dissolution between the two materials at 60 min. With regard to particle size, raw material with a $1.13{\mu}m$ particle size showed a 20% faster release rate than that of raw material with a $2.28{\mu}m$ particle size. Furthermore, fumaric acid was included in formulation as a pH modifier. That addition produced a greater than 50% improvement in dissolution rate. In conclusion, dissolution rate of nateglinide can be enhanced by optimizing its polymorphism and particle size; moreover, a synergistic effect on the enhancement of dissolution rate is obtained by including fumaric acid, a pH modifier, in the formulation.

• Journal of Korean Neurosurgical Society
• /
• v.63 no.5
• /
• pp.579-589
• /
• 2020

Objective : No optimum genetic rat Huntington model both neuropathological using an adeno-associated virus (AAV-2) vector vector has been reported to date. We investigated whether direct infection of an AAV2 encoding a fragment of mutant huntingtin (AV2-82Q) into the rat striatum was useful for optimizing the Huntington rat model. Methods : We prepared ten unilateral models by injecting AAV2-82Q into the right striatum, as well as ten bilateral models. In each group, five rats were assigned to either the 2×10¹² genome copies (GC)/mL of AAV2-82Q (×1, low dose) or 2×10¹³ GC/mL of AAV2-82Q (×10, high dose) injection model. Ten unilateral and ten bilateral models injected with AAV-empty were also prepared as control groups. We performed cylinder and stepping tests 2, 4, 6, and 8 weeks after injection, tested EM48 positive mutant huntingtin aggregates. Results : The high dose of unilateral and bilateral AAV2-82Q model showed a greater decrease in performance on the stepping and cylinder tests. We also observed more prominent EM48-positive mutant huntingtin aggregates in the medium spiny neurons of the high dose of AAV2-82Q injected group. Conclusion : Based on the results from the present study, high dose of AAV2-82Q is the optimum titer for establishing a Huntington rat model. Delivery of high dose of human AAV2-82Q resulted in the manifestation of Huntington behaviors and optimum expression of the huntingtin protein in vivo.

• Journal of Intelligence and Information Systems
• /
• v.24 no.1
• /
• pp.125-140
• /
• 2018

As one of the processes in the manufacturing industry, quality inspection inspects the intermediate products or final products to separate the good-quality goods that meet the quality management standard and the defective goods that do not. The manual inspection of quality in a mass production system may result in low consistency and efficiency. Therefore, the quality inspection of mass-produced products involves automatic checking and classifying by the machines in many processes. Although there are many preceding studies on improving or optimizing the process using the data generated in the production process, there have been many constraints with regard to actual implementation due to the technical limitations of processing a large volume of data in real time. The recent research studies on big data have improved the data processing technology and enabled collecting, processing, and analyzing process data in real time. This paper aims to propose the process and details of applying big data for quality inspection and examine the applicability of the proposed method to the dairy industry. We review the previous studies and propose a big data analysis procedure that is applicable to the manufacturing sector. To assess the feasibility of the proposed method, we applied two methods to one of the quality inspection processes in the dairy industry: convolutional neural network and random forest. We collected, processed, and analyzed the images of caps and straws in real time, and then determined whether the products were defective or not. The result confirmed that there was a drastic increase in classification accuracy compared to the quality inspection performed in the past.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 1999.05a
• /
• pp.192-197
• /
• 1999

Programmers who write distributed programs are faced with a dilemma when writing the systems communication code. If the code is written by hand or partly by hand, then the speed of the application may be maximized, but the human effort required to implement and maintain the system is greatly increased. On the other hand, if the code is generated using a CORBA IDL compiler then the programmer effort will be reduced, but the performance of the application may be poor. So we need the optimizing the code generated by CORBA IDL compiler. We introduce the techniques which have been used by typical programming languages into compilation of IDL. We separate the phase of compilation into three phase. The first phase parses interface definition in IDL, manages nested scope and generates AST(Abstract Syntax Tree). The second phase implements the optimization. The third phase generates the code in target language. In this paper, we focus on the first phase. We separate interface definition into interface and message representation from AST. This supports the separate optimization of code in second phase.

• Journal of Navigation and Port Research
• /
• v.35 no.1
• /
• pp.93-100
• /
• 2011

This dissertation analysed actuality and literatures aimed at optimizing added value of Busan Port. As far as the literatures are concerned, the limits and the direction to go of Busan Port have been reached through analysing and comparing Busan Port, Antwerp Port, and Rotterdam Port by their each function. While Rotterdam and Antwerp Port are each functioning as an integrated port disposing container freight, general freight and liquid cargo, the container of Busan port contributes over 88 percent of its cargo and the function of the others like bulk is scattered to Ulsan, Masan, and Jinjae Port. Hereby, Busan Port needs to develop its function so as not to duplicate its function with the others in Korea and add value of theirs each. As a result of the local experts about analysing actuality, it turn out that it is similar with the literatures. In macroscopic view, specialization mainly with container, general cargo disposal ability enforcement and etc. are the most important. In microscopic view, rear complex of container tier and the supply base of liquid energy.