Purpose: A city is regarded as an organic living thing that generates, changes, and fades away in relationship with many components of city. Therefore, a city has its own identity based on its historical trace. Among these elements composing a city, it is a square that makes a city more active and dynamic. Piazza Navona in Rome, Italy has played its role as significant core in the city and has distinctive function from other squares in urban ecological environments. In this study, the distinguishing function and role of Piazza Navona will be defined. Another purpose of study is to figure out what factors of Piazza Navona attracts a lot of diverse people and activities. Method: First, general understanding of function, type, and history of piazza; Second, the historical background of Piazza Navona; Third, site analysis related to surrounding environments; Fourth, architectural characteristic of Piazza Navona in terms of plan and elevation; Fifth, comparing with other representative squares in Rome such as Piazza San Pietro, Piazza del Popolo, and Piazza del Campidoglio in aspects of urban function. Result: Piazza Navona provides both citizen and visitors with an inviting place to embrace all kinds of activities including assembly, annual festival, and daily events. Its functions in the urban environments also involve a tourist attractor as landmark, place for social and cultural interaction, market, and place for meeting and leisure. It is attributed to following factors; historical background as the city center since the first century AD; its location in the center of Rome; enough size and flexibility to accommodate many people and various events; open space enclosed by surrounding buildings; historical baroque structures and sculptures of fountains; synergy effect with commercial and other tourist attractors around Piazza Navona; and comfortable accessibility.
Park, Mi-Ri;Park, Sang-Ho;Cho, Sang-Yun;Hemenway, Cynthia L.;Choi, Hong-Soo;Sohn, Seong-Han;Kim, Kook-Hyung
The Plant Pathology Journal
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v.24
no.3
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pp.289-295
/
2008
RNA-RNA interactions and the dynamic RNA conformations are important regulators in virus replication in several RNA virus systems and may also involved in the regulation of many important virus life cycle phases, including translation, replication, assembly, and switches in these important stages. The 5' non-translated region of Potato virus X(PVX) contains multiple cis-acting elements that facilitate various viral processes. It has previously been proposed that RNA-RNA interactions between various RNA elements present in PVX RNA genome are required for PVX RNA accumulation(Hu et al., 2007; Kim and Hemenway, 1999). This model was based on the potential base-pairing between conserved sequence elements at the upstream of subgenomic RNAs(sgRNAs) and at the 5' and 3' end of RNA genome. We now provide more evidence that RNA-RNA base-pairing between elements present at the 5' end and upstream of each sgRNA is required for efficient replication of genomic and subgenomic plus-strand RNA accumulation. Site-directed mutations introduced at the 5' end of plus-strand RNA replication defective mutant(${\Delta}12$) increasing base-pairing possibility with conserved sequence elements located upstream of each sgRNAs restored genomic and subgenomic plus-strand RNA accumulation and caused symptom development in inoculated Nicotiana benthamiana plants. Serial passage of a deletion mutant(${\Delta}8$) caused more severe symptoms and restored wild type sequences and thus retained possible RNA-RNA base-pairing. Altogether, these results indicate that the RNA element located at the 5' end of PVX genome involved in RNA-RNA interactions and play a key role in high-level accumulation of plus-strand RNA in vivo.
In this study, research trends in the water resources in Korea were analyzed to present regional customization and optimal operation management of groundwater resources. Detailed classification fields were determined in the water and groundwater resources. Through the analysis of examples and trends of research related to water resources and underground water resources, three improvements were presented: securing sites for long-term observable research area, evaluating water resources based on spatial units, and not reflecting the characteristics of watersheds in acts and ordinances. The research results of this study are expected to be the basis for policy judgment in determining the groundwater management policy after the group of groundwater management policy makers at the research site can identify the requirements.
Hwang, Inhyuck;Song, Jungkyu;Back, Myunggi;Ryu, Cheolho;Lee, Kwangkook;Shin, Jong Gye
Journal of the Society of Naval Architects of Korea
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v.50
no.4
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pp.262-271
/
2013
Owing to the development of mobile communication technology during the last a few years, the number of users of mobile devices such as the smartphone and the tablet PC has increased rapidly. As a result, the range of applications of the mobile devices has also been greatly expanded from an application for the convenience of daily life to an application for assisting the operations of industrial fields. Especially, portability of mobile devices can provide great help in collecting and using information on the production site. In shipbuilding production processes, it is difficult to collect changes of circumstance in the field and reflect the changes to schedule due to the low production automation rate and frequent changes in schedule. In this study, we propose a system to solve the problems of shipbuilding production processes such as the ones described above by using mobile devices. First of all, we organize the production information and production processes of the panel line through the analysis of shipyard panel line operations. Next, we have developed a system that can support the production execution plan of the panel line and monitor the production processes in the field. The system was developed utilizing application virtualization to allow access to the system from various platforms of mobile devices and PC's. The system was implemented using ooCBD methodology considering the future expansion of the system and ease of maintenance.
This paper decided the 3D shape of sandwich composite for the cradle of CT instrument, suggested the stacking sequence with satisfaction on structural criteria using the Finite Element Analysis, and introduced the manufacturing method to meet the X-ray transmission performance uniformly. The design of Cradle was considered the space between other parts, fixing method, and assembly condition with headrest part. It is decided the stacking sequence to meet the criteria that the deflection at the end point is less than 20 mm when it is applied to 135 kg load at the specific locations. In site of manufacturing method, at first, it is used the hand lay-up for carbon UD and carbon fabric/polyester resin, but it had the ununiform X-ray transmission performance due to the void and excess resin. For solving this problem, it was replaced with the infusion method for the first layer of face material and the application of carbon UD or fabric/epoxy resin prepreg for other layers. Therefor, the property of X-ray transmission was improved.
Journal of the Korea Academia-Industrial cooperation Society
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v.20
no.4
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pp.606-612
/
2019
The main causes of subsidence and sinkholes in the lower part of urban roads are sewage line foundation and inadequate compaction of backfill material. This leads to many problems, such as the breakage of joints in sewer pipes, poor connection, pipe breakage, and cracks. To solve this problem, the support factor related to the sewer foundation and the safety factor according to the excavation depth were evaluated. For the foundation of rigidity tolerance, crushed stone foundation, and abandoned concrete foundation, a recently newly developed site assembly-type lightweight plastic foundation were used. Backfill materials were applied on site (sandy soil and clayey soil) and fluid backfill was recycled onsite. To evaluate the depth of excavation and the safety factor of each sewer pipe foundation, the design load considering the load factor and the support factor was evaluated. The support coefficients were 0.377 for a crushed stone foundation, 0.243 and 0.220 for an abandoned concrete foundation ($180^{\circ}$ and $120^{\circ}$), and 0.231 for a lightweight plastic foundation and fluid backfill. Overall, the safety factor was low when using the crushed stone foundation, and the safety rate was the highest when the foreclosed concrete foundation ($180^{\circ}$) was used. In addition, when the combination of lightweight plastic and fluid backfill materials was used, the safety factor was higher than that of abandoned concrete foundation ($120^{\circ}$), which means that the newly developed lightweight plastic foundation can be used as another alternative base of a steel pipe.
The purpose of this survey was to give data and information about type and needs of Home Physical Therapy, Visiting Physical Therapy and School Physical Therapy for physical and nurse. The subjects were 154(99 physical therapists and 55 nurses) who were working at geriatric rehabilitation hospitals and children hospitals. The period of questionary collection was from the 15 of August to the 15th of September 2011. And data was analysis from 99 articles such as journals related to physical therapy, and searched with keyword 'home and visiting physical therapy' by web site and Korea National Assembly Library from 1991 to 2011. The data was analysis with percentage, mean, standard deviation and ANOVA by SPSS PC 12.0. The results were as follows; 1. The definition of 'Home Physical Therapy' has been community based on physical therapy service for the patient who had diagnosis by medical doctor, has been based on medical law. The definition of 'Visiting Physical Therapy' has been community based on physical therapy service at home for the patient who had diagnosis by medical doctor, for the national basic living security, and senior citizen over 65 years who lives alone, has been based on law for community health and law of long term health insurance. The definition of 'School Physical Therapy' has been school based on physical therapy service at school after class for the disabled children who are studying at school, has been based on special education law article 28. 2. As for the knowledge of the Home and Visiting and School Physical Therapy, both groups PT and nurse were 'I do not know'125(81.3%) of the difference the concept of 3 definitions, so it means to need education and information about the different concept of three physical therapy. As for the needs of home and visiting physical therapy, both groups of PT and Nurse were 'needs' 151(98.1%). Physical therapist showed of 'Needs' on visiting physical therapy 35(35.4%), home physical therapy 32(32.3%), and schole physical therapy 32(32.3%). Nurse showed of 'Needs' on home physical therapy 23(41.8%). visiting physical therapy 19(34.5%), school physical therapy 13(23.6%). Therefore it is necessary to have home and visiting physical therapy as for the elderly and disabled person. 3. As for the qualification of Home and Visiting physical therapist, both PT and nurse groups showed as follows; take post graduation education program for home and visiting therapy after became PT : home physical therapist 108(70.1%), visiting physical therapist 106(68.8%). So it means education center or university can be developed post graduation program for home and visiting physical therapist. 4. As for the 'Needs' of school physical therapy, both groups of PT and nurse showed as follows; 'Needs' 142(92.2%), 'Needs superviser education program' 148(96.1%), in PT group showed 'I will participate of education program' 92(92.9%). 5. As for the present states of research papers or report of home, visiting, and school physical therapy was as follows; the 103 papers for 8 fields about' the needs of home and visiting physical therapy' from 1991 to 2011, the 13 papers for 2 fields about school physical therapy from 2001 to 2011, so total papers were 114 articles.
Enhancement or diminution of leukocyte migration to the specific site might be important factors for the development of inflammatory diseases. To investigate the effects of non-steroidal anti-inflammatory drugs (NSAIDs) on chemotaxis of neutrophil, we obtained neutrophils by Hypaque-Ficoll step gradient centrifugation and tested the effects of seven drugs on the n-formyl-leucyl-phenylalanine (FMLP)-induced migration of neutrophil using a 48-well micro chemotaxis assembly. Oxyphenbutazone, phenylbutazone, sulindac, zomepirac, and ibuprofen suppressed the migration of neutrophil at the therapeutic concentrations, however, indomethacin showed stimulation effect. IC50s for inhibition of neutrophil migration by these drugs are less than 100uM. When drugs were preincubated with FMLP, no inhibition on migration of neutrophil was observed. These results indicated that inhibitory effects of these drugs on migration of neutrophil might be related to the receptor sites of neutrophil rather than molecular inactivation of chemoattractant (FMLP). In conclusion, we suggested that the property of inhibition effects on neutrophil migration of several NSAIDs might be another mode of pharmacological action for anti-iflammatory effect, which showed significant effects at concentrations below therapeutic levels, in addition to cyclooxygenase inhibition.
Yeon-Hee Kang;Sung Hee Yang;Yong In Cho;Jung-Hoon Kim
Journal of the Korean Society of Radiology
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v.17
no.6
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pp.947-955
/
2023
This study was conducted to investigate the awareness of spent nuclear fuel among residents in nuclear power plant areas and use it as basic data for establishing a disposal facility for high-level radioactive waste. 204 questionnaires collected online were analyzed using SPSS Window Ver 28.0. To verify differences between groups, t-test and one-way ANOVA were performed. And correlation analysis was conducted to confirm the relationship between variables. As a result, first, risk perception regarding nuclear-related accidents showed statistically significant differences depending on gender and educational level. The position on the construction of a permanent disposal facility for spent nuclear fuel showed a statistically significant difference depending on gender, education, and age, and the perception of the importance of each evaluation standard for establishing a spent nuclear fuel management plan showed a statistically significant difference depending on education and age. In terms of trust in information-providing institutions, trust in the National Assembly was found to be the lowest. Second, the results of the correlation analysis between variables showed that local residents are aware that an alternative to the current disposal of spent nuclear fuel is needed, and that financial support for the construction of a permanent disposal facility is needed. Therefore, in order to build a high-level radioactive waste disposal site, it is believed that it is necessary to increase trust in the government, collect opinions from local residents, and provide economic support.
Journal of the Korea institute for structural maintenance and inspection
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v.20
no.1
/
pp.104-111
/
2016
The steel frame modular housing of which the research and development has been actively carried out recently cannot be constructed through monolithic placement like the reinforced concrete deck of general structure due to the characteristics of construction method of production in the factory and assembly on the site. And floor vertical vibration and deflection caused by inhabitants' activities may become an important issue in the aspect of usability evaluation due to a decrease in the section size of member, a decrease in weight, and so on. Therefore, this study evaluated the vibration performance of deck by using formula of AISC Design Guide 11(hereinafter AISC formula) which was practically used in general for modules where a stud was and wasn't installed at the center of beam in the longitudinal direction in the modular housing to be studied, and examined the applicability of AISC formula through comparison with the results of analysis using a general-purpose analysis program. On the basis of this, a structural cause for an error to occur between analysis result and AISC formula in the deck of module in which a stud was installed was analysed, and measures for considering this were suggested. Besides, an analysis model with the variables of measures for improving the floor vibration performance of modular housing to be studied was established. And measures having excellent vibration performance and economic feasibility were suggested through vibration response analysis and economic evaluation.
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