• Tuberculosis and Respiratory Diseases
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• v.87 no.4
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• pp.505-513
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• 2024

Background: Clinical data for bacterial coinfection of the lower respiratory tract in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) are scarce. This study aims to assess the prevalence of bacterial coinfection and clinical features in NTM-PD patients. Methods: This retrospective study screened 248 patients with NTM-PD who underwent bronchoscopy between July 2020 and July 2022, from whom newly diagnosed NTM-PD patients were analyzed. Bacterial culture using bronchial washing fluid was performed at the time of NTM-PD diagnosis. Results: In the 180 patients (median age 65 years; 68% female), Mycobacterium avium complex (86%) was the most frequent NTM isolated. Bacterial coinfections were detected in 80 (44%) patients. Among them, the most common bacterium was Klebsiella pneumoniae (n=25/80, 31.3%), followed by Pseudomonas aeruginosa (n=20/80, 25%) and Staphylococcus aureus (n=20/80, 25%). Compared with NTM-PD patients without bacterial coinfections, patients with bacterial coinfections showed more frequent extensive lung involvement (33% vs. 1%, p<0.001). Additionally, compared with NTM-PD patients without P. aeruginosa infection, those with P. aeruginosa infection were older (74 years vs. 64 years, p=0.001), had more frequent respiratory symptoms (cough/excessive mucus production 70% vs. 38%, p=0.008; dyspnea 30% vs. 13%, p=0.047), and had extensive lung involvement (60% vs. 9%, p<0.001). Conclusion: Less than half of patients with newly diagnosed NTM-PD had bacterial coinfections, linked to extensive lung involvement. Specifically, P. aeruginosa coinfection was significantly associated with older age, more frequent respiratory symptoms, and extensive lung involvement.

• Nuclear Engineering and Technology
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• v.56 no.6
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• pp.2247-2257
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• 2024

To investigate the impact of the recently released pediatric reference voxel phantoms (0-, 1-, 5-, 10-, 15-year-old males and females) of the International Commission on Radiological Protection (ICRP) on organ dose estimates for radioactive iodine (RAI) treatment in pediatric patients, we calculated and analyzed pediatric-specific iodine131 S values (r_T ← thyroid) for the 30 radiosensitive organs by conducting Monte Carlo simulations using the Geant4. The gender dependency in the S values was frequently seen for the 15-year-old phantoms with higher S values of female than male. In addition, the age dependency in the S values was observed for most target organs; that is, the S values tend to decrease for older ages (e.g., ~120 times for the gonads between the adult and newborn) due mainly to the inter-organ distances generally longer for older ages. Moreover, we observed that the iodine-131 S values tend to be significantly greater by up to ~145.5 times than those of the stylized phantoms that have been widely used for organ dose estimates of pediatric RAI patients. We believe that the pediatric-specific iodine-131 S values (r_T ← thyroid) of the ICRP pediatric reference voxel phantoms should be beneficial to improve the dosimetry of pediatric RAI patients.

• Journal of Yeungnam Medical Science
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• v.4 no.1
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• pp.123-128
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• 1987

To estimate the prevalence of hypertension among the aged in urban area, the blood pressure was examined on the subjects of 565 men and 762 women of 65 years old and older among the residents of Nam-Ku and Soosung-Ku in Taegu between January and December, 1986. The mean systolic blood pressure was $136.0{\pm}25.01mmHg$ in male and $133.0{\pm}24.56mmHg$ in female. The mean diastolic blood pressure was $83.7{\pm}14.41mmHg$ in male and $82.4{\pm}14.43mmHg$ in female. There was no significant differences between male and female in both mean systolic and diastolic blood pressure. According to WHO category, the prevalence of pure systolic hypertension (${\geq}$160/<95mmHg) was 7.8% in male and 6.8% in female. The prevalence of pure diastolic hypertension(<160/${\geq}$95mmHg) was 6.0% in male and 3.9% in female. The prevalence of both systolic and diastolic hypertension (${\geq}160/{\geq}95mmHg$) was 13.5% in male and 12.9% in female. According to joint National Committee category, the percentage of normal blood pressure (/<90mmHg) was 46.7% in male and 50.8% in female. The prevalence of mild hypertension (/90=104mmHg) was 34.5% in male and 34.6% in female. The prevalance of moderate hypertension (/105=144mmHg) was 5.1% in male and 2.5% in female. The prevalence of severe hypertension (/${\geq}$115mmHg) was 2.3% in male and 3.0% in female. The prevalence of borderline isolated systolic hypertension (140-159/<90mmHg) was 9.0% in male and 6.6% in female. The prevalence of isolated systolic hypertension (${\geq}$160/<90mmHg) was 2.3% in male and 2.5% in female.

• Korean journal of communication and information
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• v.41
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• pp.200-231
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• 2008

This study content-analyzed Korean cable television programs aired from Feb. 6 to Feb. 19, 2007, focusing on the contextual variables linked to violent acts. A total of 657 PAT's (perpetrator-action-target) in the 68 programs sampled were analyzed for characters' age, sex, type, relationship, and motivation, humorization, punishment for their violent acts, and finally reality of violence. According to the results, (1) most violence occurred among male characters, who were at their ages between 20 and 39; (2) more than half of the total violent acts happened among acquaintances including family members; (3) anger, retaliation, personal or group interest, and violence for fun were ranked at the top tiers of the motivation list; (4) most violences were overlooked without punishment; (5) and about 80% of the whole violence were realistic. In terms of program types, (1) female perpetrator and victims appealed more often in drama than the other genres; (2) violence among acquaintances and simple fun as motivation were prevalent most in entertainment programs; (3) every violent act in children's programs was done by unrealistic characters. According to the analysis by program ratings, (1) while least violence appeared in '19 and older', all of the violent acts were portrayed as realistic; (2) humorization were most prevalent in the 'everyone' rating; (3) and female perpetrators and victims appealed most in the programs rated as '15 and older'. Generally, various contextualized violences displayed different distributions according to program types and ratings. The qualitative features of the current findings about cable television violence provide a fundamental data for future studies, which will explore the subsequent effects of violent media contents.

• The Journal of the Korea Contents Association
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• v.20 no.4
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• pp.244-253
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• 2020

This study aimed to assess the factors affecting the level of happiness and a sense of happiness among senior men and women, including sociodemographic characteristics, health behavior, subjective health level, and healthcare utilization, using the 2017 Community Health Survey (CHS). A total of 67,835 older adults were enrolled for the study, 27,979 males and 39,856 females. The results showed that education level and total household income affected the happiness in female elderly, while having a spouse increased happiness in male elderly. In addition, both male elderly and female felt a great of happiness when they had good health behaviors, perceived themselves to be in good health, and had no restrictions with healthcare utilization. Subjective health status and healthcare utilization seem to have a substantial impact on happiness because older adulthood is a period marked with increased physical vulnerability compared to other age groups due to diminished physiological functions. Based on these results, the government should expand subsidies for welfare for the aged to provide lifelong education opportunities and the existing elderly education and programs in health-related organizations should reflect the characteristics of the elderly. Furthermore, social service systems and programs related to the elderly should be re-evaluated so as to develop services and programs tailored to the elderly to promote their happiness more effectively.

• Journal of Periodontal and Implant Science
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• v.27 no.1
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• pp.235-248
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• 1997

The purpose of this study was to investigate the width of attached gingiva of 414 subjects with healthy gingiva, or early stage of gingivitis. We compared the differences according to the tooth location, age (Yonger group : $14{\sim}30$, Older group : $31{\sim}67$) and gender. In addition, we compared the width of attached gingiva in the subjects with less than 2 sites of gingival recession($Re{\leq}2$) and the subjects with more than 3 sites of gingival recession($Re{\geq}3$) to study the relationship between the gingival recession and the width of attached gingiva. The results were as follows : 1. The width of keratinized gingiva was widest in maxillary incisors($5.3{\pm}1.4mm$) and narrowest in mandibular right 1st bicuspid and mandibular right and left 2nd molars($3.5{\pm}1.1mm$). 2. The width of attached gingiva was widest in maxillary right central incisor($3.8{\pm}1.5mm$) and narrowest in mandibular right 2nd molar($1.2{\pm}1.0mm$). 3. In the comparison between the age groups, the width of keratinized in older group was significantly (p<0.05) wider than that in younger group in maxillary right and left 1st bicuspids, mandibular right and left 1st and 2nd molars, maxillary right and left cuspids and mandibular right 1st bicuspid. There was no significant difference in the width of attached gingiva between the two groups except for maxillary right and left 1st molars and maxillary left 2nd molar. 4. In the comparison between male group and female group, in maxillary right and and left lateral incisors and cuspids, mandibular right and left cuspids and 1st bicuspids, the width of attached gingiva in female was significantly(p<0.05) wider than that in male group. 5. In the comparison between the Re 3 group and Re 2 group, there was no significant difference except for maxillary right and left 2nd molars and maxillary left 1st molar. 6. The frequency of gingival recession was m the order of mandibular right 1st bicuspid(16.6%), maxillary right 1st bicuspid(13.7%), maxillary and mandibular left 1st bicuspids (13.4%), mandibular left cuspid (10.5%), maxillary left and mandibular right cuspids(10.1%) and maxillary right cuspid(7.9%).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.371-381
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• 2019

This study explored how retirement satisfaction or dissatisfaction influences on retirees' life satisfaction, comparing to workers and the gender differences were examined. The study sample was 2,609 persons (1,886 workers, 723 retirees) aged 45 or older who participated in the 1-2 waves of the Korean Longitudinal Study of Ageing (KLoSA), and the retirees were classified into continuously dissatisfied retirees and satisfied retirees during wave 1 and 2. Using SPSS 21.0, the multiple regression models were examined, and in order to clarify the gender difference, the multi-group analysis and the wald-test were conducted to test the difference of the regression coefficients according to gender using Mplus 7.3. According to the results, the life satisfaction of dissatisfied retirees was lower than that of the employed, but when satisfied with retirement, the life satisfaction was higher than that of the employed. In addition, the dissatisfied retirees in both gender were less satisfied with life than the employed, and this effect was greater in female group. However, the life satisfaction of female satisfied with retirement was higher than that of the employed, whereas the evidence of the male influence was not found to be significant. Based on the results of this study, discussion about heterogeneity of retirees and gender differences in life span were presented.

• Journal of Preventive Medicine and Public Health
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• v.55 no.6
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• pp.529-538
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• 2022

Objectives: This study aimed to identify the current patterns of cancer incidence and estimate the projected cancer incidence and mortality between 2020 and 2035 in Korea. Methods: Data on cancer incidence cases were extracted from the Korean Statistical Information Service from 2000 to 2017, and data on cancer-related deaths were extracted from the National Cancer Center from 2000 to 2018. Cancer cases and deaths were classified according to the International Classification of Diseases, 10th edition. For the current patterns of cancer incidence, age-standardized incidence rates (ASIRs) and age-standardized mortality rates were investigated using the 2000 mid-year estimated population aged over 20 years and older. A joinpoint regression model was used to determine the 2020 to 2035 trends in cancer. Results: Overall, cancer cases were predicted to increase from 265 299 in 2020 to 474 085 in 2035 (growth rate: 1.8%). The greatest increase in the ASIR was projected for prostate cancer among male (7.84 vs. 189.53 per 100 000 people) and breast cancer among female (34.17 vs. 238.45 per 100 000 people) from 2000 to 2035. Overall cancer deaths were projected to increase from 81 717 in 2020 to 95 845 in 2035 (average annual growth rate: 1.2%). Although most cancer mortality rates were projected to decrease, those of breast, pancreatic, and ovarian cancer among female were projected to increase until 2035. Conclusions: These up-to-date projections of cancer incidence and mortality in the Korean population may be a significant resource for implementing cancer-related regulations or developing cancer treatments.

• Clinical and Experimental Pediatrics
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• v.48 no.10
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• pp.1139-1142
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• 2005

Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age. Results : 211 patients 8 years of age and older(1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9 : 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial(CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction. Conclusion : Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities(25.4% : 19.8%) and CA aneurysms(7.6% : 4.0%).

• Sleep Medicine and Psychophysiology
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• v.28 no.2
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• pp.78-85
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• 2021

Objectives: When elderly patients show depressive symptoms, discrimination between depressive disorder and prodromal phase of Alzheimer's disease is important. We tested whether a quantitative electroencephalogram (qEEG) marker was associated with cerebral amyloid-β (Aβ) deposition in older adults with depression. Methods: Non-demented older individuals (≥ 55years) diagnosed with depression were included in the analyses (n = 63; 76.2% female; mean age ± standard deviation 73.7 ± 6.87 years). The participants were divided into Aβ+ (n = 32) and Aβ- (n = 31) groups based on amyloid PET assessment. EEG was recorded during the 7min eye-closed (EC) phase and 3min eye-open (EO) phase, and all EEG data were analyzed using Fourier transform spectral analysis. We tested interaction effects among Aβ positivity, condition (EC vs. EO), laterality (left, midline, or right), and polarity (frontal, central, or posterior) for EEG alpha band power. Then, the EC-to-EO alpha reactivity index (ARI) was examined as a neurophysiological marker for predicting Aβ+ in depressed older adults. Results: The mean power spectral density of the alpha band in EO phase showed a significant difference between the Aβ+ and Aβ- groups (F = 6.258, p = 0.015). A significant 3-way interaction was observed among Aβ positivity, condition, and laterality on alpha-band power after adjusting for age, sex, educational years, global cognitive function, medication use, and white matter hyperintensities on MRI (F = 3.720, p = 0.030). However, post-hoc analyses showed no significant difference in ARI according to Aβ status in any regions of interest. Conclusion: Among older adults with depression, increased power in EO phase alpha band was associated with Aβ positivity. However, EC-to-EO ARI was not confirmed as a predictor for Aβ+ in depressed older individuals. Future studies with larger samples are needed to confirm our results.