• 제목/요약/키워드: old male

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Body Height Effect on Brain Volumes in Youth Decreases in Old Age in Koreans

  • Koh, In-Song
    • Interdisciplinary Bio Central
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    • 제3권3호
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    • pp.11.1-11.5
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    • 2011
  • The MRI (magnetic resonance imaging) volumetric analysis of the brain was performed in 59 healthy elderly Koreans (aged 62-76 years; 34 male, 25 female) to investigate whether the previously reported significant correlations between body height and brain volumes in the young aged Koreans (20's) still exist in the old aged Koreans (60's and 70's). Unlike previously reported significant correlations in the young aged Koreans, neither the correlation between whole brain volume and body height in male nor the correlation between cerebellar volume and body height in female show any significance in the old aged Koreans. The significant correlation between body height and whole brain volume was still observed when both male and female data were combined (r=0.27, P<0.05), but the correlation coef-ficient and the level of significance markedly decreased from those of previously reported Korean youth data (r=0.67, P<0.01). Simple linear regression analysis shows decrease of explanatory power of height (measured in $r^2$) from 44% in the youth group to 7% in the old age group on the variance of whole brain volume. Multiple linear regression analysis shows that age and sex, rather than height, are major explanatory variables for whole brain volume in the old aged Koreans. The loss of correlations in the aged group is suspected to be mainly due to age related brain volume changes.

40세 이후 남성의 골밀도 관련 요인과 골다공증의 유병률 (Factors Influencing in the Bone Mineral Density and the Incidence of the Osteoporosis among Male Older than 40 Years Old)

  • 모은희;조정근;이상호;임청환;최지원
    • 한국콘텐츠학회논문지
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    • 제8권10호
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    • pp.241-250
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    • 2008
  • 의학과 과학의 발전으로 인한 고령인구의 증가로 여성에게 뿐만이 아니라 남성에서도 골다공증에 의한 골절의 빈도가 증가하면서 남성 골다공증에 대한 관심이 높아지고 있다. 이에 본 연구는 40세 이후 남성의 골밀도에 관련된 요인을 알아보고 이러한 병인으로 인한 골다공증의 유병률을 조사하여 남성 골다공증의 예방과 치료대책을 위한 기초 자료를 제공하고자 한다. 건강 검진에서 골밀도 검사를 시행한 40세 이후 남성을 대상으로 한 본 연구에서 L-spine의 골감소증과 골다공증은 각각 45%, 12.9%의 유병률을 보였고, Femur에서는 51.9%, 7.63%의 유병률을 보여 미국이나 유럽에서 50세 이상 남성을 대상으로 한 연구 결과 수치보다 높게 관찰되었다. L-spine의 경우 연령과 골감소증 및 골다공증 유병률이 유의한 차이를 보였고, Femur에서 역시 연령과 골다공증의 유병률이 유의한 연관성을 가지는 것으로 조사되었다. 연령이 증가할수록 L-spine, Femur 두 부위 모두 평균 BMD가 낮아지는 것으로 조사되었고, 체중이 증가할수록, 체질량지수(BMI, kg/$m^2$)가 높을수록 골다공증의 유병률은 감소하는 음의 상관관계를 가졌다. 운동, 흡연, 음주는 골다공증의 유병율과 유의한 연관성이 없는 것으로 조사되었으나, 운동의 횟수, 흡연기간, 음주횟수는 골 양을 변화시켜 남성 골밀도에 영향을 주는 인자가 되고 있다.

Mycobacterium Avium-intracellulare Complex와 M. Fortuitum에 의한 폐항산균증(肺抗酸菌症) 3례(例) (Nontuberculous Pulmonary Infection in Two Patients with Mycobacterium avium-intracellulare Complex and a Patient with M. fortuitum)

  • 김상재;홍영표;배길한;김성진;진병원;정충모
    • 대한미생물학회지
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    • 제17권1호
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    • pp.87-93
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    • 1982
  • Two cases of pulmonary disease in a 54 year-old female and a 70 year-old male patient due to Mycobacterium avium-intracellulare complex(MAIC) and a case of pulmonary infection ina 69 year-old male patient due to M. fortuitum(MF) were found recently in this institute. All three patients had a long history of anti-tuberculous chemotherapy because they were initially diagnosed as pulmonary tuberculosis. A 70 year-old male patient infected with MAIC had an unsuccessful chemotherapy history of isoniazid(INH), para-aminosalicylic acid(PAS) and streptomycin(SM) with an incomplete, temporary, symptomatic improvement, for three years since 1964 when he was first diagnosed as pulmonary tuberculosis on physical examination. A 54 year-old female patient infected with MAIC also had an unsuccessful chemotherapy history with the various anti-tuberculous drugs since 1958. Both patients discharged large number of MAIC in their sputum specimens for at least more than one year, but no M. tuberculosis at all. A 69 year-old male patient infected with MF was diagnosed as moderately advanced pulmonary tuberculsis in 1977. Combined chemotherapy with INH+PAS+pyrazinamide(PZA) improved his clinical symptoms, however, his chest radiograph was deteriorated again in 1980 one year after he stopped therapy. Therefore he started chemotherapy again with INH+ethionamide(TH)+cycloserine(CS) but no improvement was noticed. MF was cultured from his sputum in August 1981 and he continuously discharged the same bacilli until last examination of January 1982. Whether all three patients were initially !infected with nontuberculous mycobacteria or complicated with predisposing tuberculosis was not clear because there were no reliable bacteriological examination records.

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인두와 두개안면골격에 관한 방사선학적 연구 (A ROENTGENOCEPHALOMETRIC STUDY OF THE PHARYNX AND CRANIOFACIAL SKELETON IN KOREAN)

  • 강우곤;이상래
    • 치과방사선
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    • 제12권1호
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    • pp.81-103
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    • 1982
  • The aim of this study was to investigate the variation in shape, size and area of the pharynx and adenoids, and to analyze the relationship between pharyngeal cavity and upper facial cranium which effected on morphology of those parts in Korean. Age changes and sex differences in those areas were comprised in this study. Materials included 272 lateral cephalograms, which were divided into 4 groups by age; (1) 7-year-old group consisted of 29 males and 30 females, (2) 12-year-old group consisted of 30 males and 30 females, (3) 17-year-old group consisted of 30 males and 40 females, (4) 20-year-old group consisted of 37 males and 46 females. In subjects each variable was measured and evaluated statistically introducing 17 reference points and 17 reference lines respectively. Conclusions from this study were as follows. 1. Linear measurements of the bony nasopharynx revealed that the depth and height were larger in male than those in female in 17 and 20-year-old groups. 2. Linear measurements of the upper facial cranium were larger in male than those in female in all age groups. 3. Angular measurements of the bony nasopharynx and upper facial cranium did not show, on an average, sex differences in each age group. 4. As regards area of the bony nasopharynx, it increased gradually with age in both sexes. And the area was greater in male than that in female in 17 and 20-year old groups. 5. There were sex differences in area of the adenoids of which the area was larger in male than that in female in 17 and 20-year-old groups. And the area reached a peak at 17-year-old group in male and at 12 year-old group in female. 6. Area of the pharyngeal cavity increased gradually with age in both sexes, but no sex differences were noted in each age group. 7. Rate of area of the adenoids to that of the pharyngeal cavity decreased continually with age, and no sex differences were noted in all age groups. 8. In amounts and its differences of the growth, there were sex differences in the posterior upper facial height, and were not in area of the bony nasopharynx, pharyngeal cavity and adenoids in each age group.

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영구치(永久齒) 치배형함(齒胚形咸)에 관(關)한 연구(硏究) (STUDIES ON THE AMOUNTS OF DEVELOPING PERMANENT TOOTH GERM)

  • 김진태
    • 대한소아치과학회지
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    • 제5권1호
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    • pp.7-11
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    • 1978
  • Of 633 children, 334 in male and 299 in female, whose ages ranged from 3 to 13 years old, the amounts of development of teeth germ were observed according to ages with oblique lateral cephalogram to study the developing state of teeth germ of mandibular premolars. The results were as followings; 1. The time of actively develop:ng tooth germ was observed about 10 years old both in male and in female. 2. The increasing rate of development of tooth germ a year was higher in female than in male at mandibular 1st premolar and in male than in female at mandibular 2nd premolar. 3. Age of complete tooth germ development was earlier in female than in male at mandibular 1st and 2nd premolars.

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내엽형 폐격리증;3례 보고 (Intralobar Pulmonary Sequestration; A Report of 3 Cases)

  • 은종화
    • Journal of Chest Surgery
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    • 제26권7호
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    • pp.568-570
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    • 1993
  • Pulmonary sequestration is a congenital malformation in which a mass of pulmonary tissue is detached from the normal lung and receives its blood supply from a systemic arterys from the thoracic aorta or the abdominal aorta, or occasionally from an intercostal artery. We have experienced the three cases of the intralobar pulmonary sequestration. In the first case a 5 year old male was admitted of productive cough and abdominal distension, and chest film showed pneumonic infiltration in RLL. Second case was 26 year old male patient complaining Rt. chest discomfort and hemoptysis and chest X-ray revealed infiltration in Rt. LLF. Third case was 26 year old male patient whose complaint was hemoptysis. Chest x-ray showed hazy density in Lt. lower lung field. In the all cases, the aortograms were performed and the confirmed diagnosis was intralobar pulmonary seqeustration.

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대혈관전위증 수술 3례 보 (Operation using valved conduit in TGA: report of 3 cases)

  • 유회성
    • Journal of Chest Surgery
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    • 제16권4호
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    • pp.452-457
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    • 1983
  • Transposition of great arteries is relatively common cyanotic heart disease excluding TOF and is divided to two groups: complete TGA and congenitally corrected TGA. We experienced operations in 3 cases of TGA, the 1st case was 12 year-old male: TGA[SDD] + VSD+PS and treated with Rastelli`s operation, but expired due to low cardiac output syndrome postoperatively. The 2nd case,13 year-old male was also TGA[SDD]+VSD+PS and treated with Rastelli`s operation with good operative result. The 3rd case was 18-year old male: congenitally corrected TGA[SLL]+VSD+ PA+ASD and operation was done according to the met. hod reported by Danielson et al in 1980. Post-operative AV block led to implantation of permanent epicardial pacemaker with good result.

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노인의 고관절 ROM에 관한 연구 (A Study on Hip Joint ROM of the Elderly)

  • 엄기매;양윤권;장수경
    • 대한물리치료과학회지
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    • 제9권2호
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    • pp.67-75
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    • 2002
  • The purpose of this study is to know the average of hip joint range of motion and difference according to the aging for the elderly. This study consisted of elder male(n=75) and elder female(n=109). The result of assessment and analysis in hip pint range of motion are as follows : 1) The average hip flexion(knee flexed) joint range of motion in 60-69(from sixty to sixty-nine)years old are $104.26^{\circ}$(Left-Male), $101.00^{\circ}$(Right-Male), $107.05^{\circ}$(Left-Female), $107.05^{\circ}$(Right-Female). 70-79years old are $104.59^{\circ}$(L-M), $102.05^{\circ}$(R-M), $105.73^{\circ}$(L-F), $108.75^{\circ}$(R-F). 80-89years old are $101.53^{\circ}$(L-M), $101.13^{\circ}$(R-M), $96.83^{\circ}$(L-F), $97.67^{\circ}$(R-F). There was significant difference in hip flexion(knee flexed) among female group(p<.01). The average hip flexion(knee extended) joint range of motion in 60-69(from sixty to sixty-nine)years old are $73.13^{\circ}$(Left-Male), $72.04^{\circ}$(Right-Male), $77.29^{\circ}$(Left-Female), $75.97^{\circ}$(Right-Female). 70-79years old are $74.95^{\circ}$(L-M), $72.19^{\circ}$(R-M), $76.73^{\circ}$(L-F), $76.65^{\circ}$(R-F). 80-89years old are $70.83^{\circ}$(L-M), $70.37^{\circ}$(R-M), $69.00^{\circ}$(L-F), $69.00^{\circ}$(R-F). There was significant difference in left hip flexion(knee extended) among female group(p<.05). 2) The average hip extension joint range of motion in 60-69years old are $13.09^{\circ}$(L-M), $12.78^{\circ}$(R-M), $10.97^{\circ}$(L-F), $10.68^{\circ}$(R-F). 70-79years old are $8.95^{\circ}$(L-M), $8.48^{\circ}$(R-M), $11.24^{\circ}$(L-F), $10.90^{\circ}$(R-F). 80-89 years old are $8.40^{\circ}$(L-M), $8.23^{\circ}$(R-M), $7.33^{\circ}$(L-F), $7.33^{\circ}$(R-F). There was significant difference in left(p<.01) and right(p<.05) hip extension among male group(p<.05). 3) The average hip abduction joint range of motion in 60-69 years old are $33.04^{\circ}$(L-M), $33.17^{\circ}$(R-M), $33.16^{\circ}$(L-F), $33.37^{\circ}$(R-F). 70-79 years old are $31.00^{\circ}$(L-M), $30.05^{\circ}$(R-M), $32.44^{\circ}$(L-F), $32.68^{\circ}$(R-F). 80-89 years old are $29.07^{\circ}$(L-M), $27.90^{\circ}$(R-M), $28.17^{\circ}$(L-F), $28.67^{\circ}$(R-F). There was no significant difference among group. 4) The average hip adduction pint range, of motion in 60-69years old are $29.57^{\circ}$(L-M), $29.35^{\circ}$(R-M), $31.87^{\circ}$(L-F), $31.89^{\circ}$(R-F). 70-79, years old are $27.41^{\circ}$(L-M), 27.00(R-M) $30.85^{\circ}$(L-F), $31.28^{\circ}$(R-F). 80-89 years old are $26.87^{\circ}$(L-M), $26.63^{\circ}$(R-M), $24.67^{\circ}$(L-F), $24.83^{\circ}$(R-F). There was significant difference in hip abduction among female group(p<01). 5) The average hip external rotation pint range of motion in 60-69years old are $32.26^{\circ}$(L-M), $31.17^{\circ}$(R-M), $33.53^{\circ}$(L-F), $34.42^{\circ}$(R-F). 70-79 years old are $31.64^{\circ}$(L-M), $28.62^{\circ}$(R-M) $31.29^{\circ}$(L-F), $31.45^{\circ}$(R-F). 80-89 years old are $26.40^{\circ}$(L-M), $26.07^{\circ}$(R-M), $24.77^{\circ}$(L-F), $24.27^{\circ}$(R-F). There was significant difference in left(male, female p<.01) and right(female p<.0l) hip external rotation among group. 6) The average hip internal rotation joint range of motion in 60-69years old are $30.30^{\circ}$(L-M), $28.13^{\circ}$(R-M), $34.27^{\circ}$(L-F), $36.03^{\circ}$(R-F). 70-79years old are $31.24^{\circ}$(L-M), $29.57^{\circ}$(R-M), $28.51^{\circ}$(L-F), $29.10^{\circ}$(R-F). 80-89 years old are $24.63^{\circ}$(L-M), $24.40^{\circ}$(R-M), $24.27^{\circ}$(L-F), $24.27^{\circ}$(R-F). There was significant difference in left(male p<.05, female p<.01) and right(female p<.01) hip internal rotation among group.

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반추수의 혈청과 장기조직의 Creatine Phosphokinase(CPK) 총활성 및 CPK Isoenzyme 분획에 관한 연구 (Studies on the Total Creatine Phosphokinase (CPK) Activities and CPK Isoenzymes Fractions of the Sera and Organ Tissues in Ruminant)

  • 윤상보;김덕환
    • 한국임상수의학회지
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    • 제9권2호
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    • pp.433-449
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    • 1992
  • Total CPK activities and CPK isoenzymes fractions of the sera and tissues were examined to obtain the physiological basic data of ruminant available in veterinary clinical practice. For the sera total CPK activities and CPK isoenzymes fractions, total 39 clinically healthy Korean native goats (3 to 10 months old, IS of female and 18 of male) and 6 of Korean native goats (1 to 2 years old, 3 of female and 3 of male) were used. Seventeen Korean native cattle (3 to 6 years old, 10 of female and 7 of male) and 27 Holstein-Friesian cattle (2 to 8 months old, 7 of female and 3 to 12 years old, 20 of female) were also examined for the sera total CPK activities and CPK isoenzymes fractions. For the total CPK activities and CPK isoenzyme fractions, 3 of female Korean native goats (7 months old), 3 of female Korean native cattle (2 years old) and 3 of dairy cattle (2 years old, 2 of female and 1 of male) were used. The tissues examined were the cerebrum (2 of Korean native cattle), spinal cord (1 of Korean native cattle), heart, lung, diaphragm, reticulum, liver, spleen, kidney, jejunum. colon and femoral muscle. The results obtained were as follows : 1. In Korean native goats less than 1-year-old. serum total CPK activities were 67.8${\pm}$17.7(39.0~96.5) IU/$\ell$ in female and 63.4${\pm}$19.0(28.7~94.4) IU/$\ell$ in male. Further they were 67.0${\pm}$5.3(59.5~70.7) IU/$\ell$ and 54.5${\pm}$11.1(39.1~69.4) IU/$\ell$ in female and male Korean native goats over 1-year-old, respectively. Serum total CPK activities of female were slightly higher than those of male. Significance between age and sex was not found. 2. Serum total CPK activities were 56.8${\pm}$19.7(27.6~90.5) IU/$\ell$ and 65.6${\pm}$10.8(52.8~78.0) IU/$\ell$ in female and male Korean native adult cattle, respectively, Serum total CPK activities of male were slightly higher than those of female, but they were not significant 3. Serum total CPK activities we,e 72.5${\pm}$8.2(57.2~83.2) IU/$\ell$ and 60.8${\pm}$12.5(42.7~80.6) IU/$\ell$ in calves and adult of dairy acttle, respectively. Serum total CPK activities of calves were significantly higher than those of adult(p<0.05). 4. In Korean native goats less than 1-year-old, serum CPK isoenzymes fractions were high with decreasing order of MM>MB>BB and MM>BB>MB in female and male, respectively. Further they were high with decreasing order of MM>MB>BB and MM>B8>MB in female and male Korean native goats over 1-year-old, respectively. The main fractions of CPK isoenzymes were MM in sera of Korean native goats. 5. Serum CPK Isoenzyme fractions were high with decreasing order of MM>MB>BB In both female and male of Korean native cattle. The main fraction among them was MM. 6. Serum CPK isoenzymes fractions were high with decreasing order of MM>BB>MB in both calves and adult of dairy cattle. The main fraction among them was MM. 7. Total CPK activities were high with decreasing order of the femoral muscle>kidney>reticulum>diaphragm>liver>spleen>heart>colon>lung>jejunum in Korean native goats. 8. Total CPK activities were high with decreasing order of the spinal cord >cerebrum>femoral muscle>reticulum>kidney>liver>spleen>diaphragm>lung>colon>heart>jejunum in Korean native cattle. 9. Total CPK activities were high with decreasing order. of the femoral muscle >liver>retoculum>kidney>heart>colon>lung>spleen>jejunum>diaphrasm in dairy cattle. 10. The pattern of the cardiac CPK isoenzymes fractions was identical in Korean native goats, Korean native cattle and dairy cattle. They were high in the order of MM>MB without BB fractions and the main fraction was MM. 11. The pattern of the pulmonary CPK isoenzymes fractions was the same Korean native goats, Korean native cattle and dairy cattle. They were high with decreasing order of MM>MB>BB and the main fraction among them was MM. 12. The pattern of CPK isoenzymes fractions of the diaphragm was Identical in Korean native goats and Korean native cattle. They were high with decreasing order of MM >BB >MB except dairy cattle (MM>MB>BB) but the main fraction among them was MM. 13. The pattern of the reticular CPK isoenzymes fractions was identical in Korean native cattle and dairy cattle. They were high with decreasing order of BB >MM >MB except Korean native goats(BB>MB>MM) but the main, fraction among them was BB 14. The pattern of the hepatic CPK isoenzymrs fractions was identical in Korean native cattle and dairy cattle. They were high with decreasing order of MB >BB >MM except Korean native goats(MB>MM>BB)but the main fraction was MB. 15. The splenic CPK isoenzymes fractions showed different pattern. They were high with decreasing order of MB>BB>MM, MM>BB>MB and BB>MB>MM in Korean native goats, Korean native cattle and dairy cattle, respectively. The main fraction among them was different from each other. 16. The pattern of the renal CPK isoenzymes fractions was identical in Korean native cattle and dairy cattle. They were high with decreasing order of MM >MB>BB except Korean native goats(BB>MB>MM). 17. The CPK isoenzymes fractions of the Jejunums showed different pattern. They were high with decreasing order MM>MB>BB, MM>BB>MB and BB>MM>MB in Korean native goats, Korean native cattle and dairy cattle, respectively. The main fractions were MM In Korean native goats and Korean native cattle, and BB in dairy cattle. 18. The colonic CPK isoenzymes fractions showed different pattern. They were high with decreasing order of MM>MB>BB, MM>BB>MB and BB>rrfB>MM in Korean native goats, Korean native cattle and dairy cattle, respectively. The main fractions were MM in Korean native goats and Korean . native cattle, and BB in dairy cattle. 19. The cerebral CPK isoenzymes fractions were high with decreasing order of BB >MM without MB detected in Korean native cattle and those of spinal cord were high with decreasing order of BB >MM >MB. The main fractions in both cerebrum and spinal cord were BB.

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초생추(初生雛)의 각(各) 장기(臟器)에 있어서 방사성(放射性) 린(燐)$(^{32}P)$의 흡수분포(吸收分布)에 관한 실험적 연구 (The experimental study on the distribution of radioactive phosphorus-32 to several organs in one-day and seven-days old chicks)

  • 정영채;이현자
    • Journal of Nutrition and Health
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    • 제3권2호
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    • pp.101-106
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    • 1970
  • Radioactive Phosphorus $(^{32}P)$ was administered intramuscularlly to the newly hatched chicken in the purpose of determination of the uptake and the distribution, as related to sex and hour differences of the several organs of the bodies. $2\;{\mu}\;of\;^{32}P$ was administered to each chick, and the distribution of 32P was observed in 1 hour and 24 hours after administration. In this experiment 80 heads of chicken were used(40 chicken were one day and 40 chicken were 7 days old) and the results obtained as follows: 1. The tissue showed an uptake rate of $^{32}P$ dose per 100 milligram of tissue in one day old chicken, with the following sequence: Males (1 hour): Femur. Liver. G., Muscle. Testis. Brain (24 hour): Femur, Testis, Gastrocnemius Muscle, Liver, Brain. Female(1 hour): Femur, Liver, Gastronemius Muscle, Ovary, Brain. (24 hour): Femur, Liver, Gastrocnemius Muscle, Ovary, Brain. 2. In 1 hour, the uptake rate of $^{32}P$ of the tissues showed significant difference between the male and the female except the gastrocnemius muscle and the brain in one day old group, but they were no significance except the testis and ovary after 24 hours. 3. The distribution of $^{32}P$ of the tissues exhibited higher in 1 hour than in 24 hours except the femur, the brain of the male and female, the brain and gastrocnemius muscle of the female in one day old group. 4. The tissue showed an uptake rate of $^{32}P$ dose per 100 miligram of tissue in 7days old chicken, with the following sequence: Male (1 hour): femur, liver, gastrocmenius muscle, testis, brain. (24 hour): femur, testis, gastrocmenius muscle, liver, brain. Female(1 hour): femur, liver, gastrocmenius muscle, ovary, brain. (24 hour): femur, ovary, liver, gastrocmenius muscle, brain. 5. The distribution of $^{32}P$ of the tissues showed no significant difference between the male and the female except the testis and ovary after 24 hours in 7 days old chicken group. 6. The distribution of $^{32}P$ the tissues exhibited higher in 1 hour in 24 hours except the femur, the brain of the male and the female, the brain and the ovary of the female in 7 days old chicken group.

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