• Title/Summary/Keyword: observational methods

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Assessment and Methods of Nutritional Support during Atropinization in Organophosphate and Carbamate Poisoning Cases (아트로핀으로 치료하는 유기인계와 카바메이트 중독 환자의 영양지원 평가와 방법)

  • Park, Jong-uk;Min, Young-gi;Choi, Sangcheon;Ko, Dong-wan;Park, Eun Jung
    • Journal of The Korean Society of Clinical Toxicology
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    • v.18 no.2
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    • pp.123-129
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    • 2020
  • Purpose: Atropine is an antidote used to relieve muscarinic symptoms in patients with organophosphate and carbamate poisoning. Nutritional support via the enteral nutrition (EN) route might be associated with improved clinical outcomes in critically ill patients. This study examined the administration of nutritional support in patients undergoing atropinization, including methods of supply, outcomes, and complications. Methods: A retrospective observational study was conducted in a tertiary care teaching hospital from 2010 to 2018. Forty-five patients, who were administered with atropine and on mechanical ventilation (MV) due to organophosphate or carbamate poisoning, were enrolled. Results: Nutritional support was initiated on the third day of hospitalization. Thirty-three patients (73.3%) were initially supported using parenteral nutrition (PN). During atropinization, 32 patients (71.1%) received nutritional support via EN (9) or PN (23). There was no obvious reason for not starting EN during atropinization (61.1%). Pneumonia was observed in both patient groups on EN and PN (p=0.049). Patients without nutritional support had a shorter MV duration (p=0.034) than patients with nutritional support. The methods of nutritional support during atropinization did not show differences in the number of hospital days (p=0.711), MV duration (p=0.933), duration of ICU stay (p=0.850), or recovery at discharge (p=0.197). Conclusion: Most patients undergoing atropinization were administered PN without obvious reasons to preclude EN. Nutritional support was not correlated with the treatment outcomes or pneumonia. From these results, it might be possible to choose EN in patients undergoing atropinization, but further studies will be necessary.

Program Theory Evaluation of a Lifestyle Intervention Program for the Prevention and Treatment of Metabolic Syndrome (대사증후군 상태 개선을 위한 생활습관 중재프로그램의 프로그램 이론 평가)

  • Yoo, Seung-Hyun;Kim, Hye-Kyeong
    • Korean Journal of Health Education and Promotion
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    • v.27 no.4
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    • pp.165-175
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    • 2010
  • Objectives: The purpose of this study is to evaluate the program theory of a lifestyle intervention program for the prevention and treatment of metabolic syndrome. Methods: The program evaluated is a tailored intervention for multiple health behavior associated with metabolic syndrome which is informed by theoretical constructs from the Intervention Mapping and Transtheoretical model. The program components include one-to-one health counseling, a self-management handbook, and a health diary. To evaluate program impact theory we examined the logic of program goals and objectives, intervention methods and strategies, and the theoretical constructs of program materials through document review and matrix building. Results: This evaluation has found that the intervention program applied social cognitive theory constructs to design intervention methods and strategies in addition to the Transtheoretical model: self-monitoring for goal setting and monitoring skill, outcome expectation for the benefits of health behavior change, and interaction with environment for observational learning through modeling. While the intervention addresses multiple determinants and behaviors, it is limited to an individual level and lacks social and environmental approaches. Following the Transtheoretical framework, the contents of the intervention materials were developed utilizing consciousness raising as a main strategy for earlier stages of change, and counterconditioning and stimulus control for later stages of change. Conclusion: Program theory evaluation can be a process of enhancing program validity. It would also be necessary for providing basis for efficient program implementation. When comparisons of program theory between similar programs are possible, program theory and validity will be strengthened when comparisons of program theories between similar programs are possible.

An Analysis of the Trends of Korean Medicine Treatments for Trigger Finger (방아쇠 수지에 대한 한의학적 치료 연구 동향 분석)

  • Choi, Jae-Yong;Lee, Sang-Gun;Kim, Ho;Yoo, Sang-Joon;Kang, Dong-Hyeob;Lee, Do-Hoon;Choi, Ki-Won;Lee, Yu-Jin
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.65-74
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    • 2021
  • Objectives The purpose of this review is to analyze the trends of Korean medicine treatment for trigger finger. Methods Clinical papers using Korean medicine to treat trigger finger were searched in five online databases-Koreanstudies Information Service System, Oriental Medicine Advanced Searching Integrated System, ScienceON, Research Information Sharing Service, and PubMed. Nine studies were selected, and we analyzed their characteristics according to the author, year, number/gender/age of patients, duration of disease, duration of treatment, intervention method, measurement methods, and results. Results Seven case report studies, one prospective observational study, and one randomized controlled trials (RCTs) were selected in online databases, and there were no review studies. The most frequently used therapies were pharmacopuncture and acupuncture treatment. visual analogue scale, Quinnell's classification of triggering, was frequently used for measurement methods. All nine studies had therapeutic effects. Conclusions We reviewed studies of Korean medicine treatments for trigger finger, in this study. However, there are limitations that seven of the nine selected papers were case papers, and the number of papers was small. This paper suggests that a higher level of research and more studies on Korean medicine treatments of trigger finger need to be conducted.

The association between dietary sodium intake and obesity in adults by sodium intake assessment methods: a review of systematic reviews and re-meta-analysis

  • Jounghee Lee;Cheongmin Sohn;Oh-Yoen Kim;Young-Min Lee;Mi Ock Yoon;Myoungsook Lee
    • Nutrition Research and Practice
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    • v.17 no.2
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    • pp.175-191
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    • 2023
  • BACKGROUND/OBJECTIVES: The scientific evidence of a sodium-obesity association is limited by sodium intake assessments. Our specific aim is to synthesize the association between dietary sodium intake and obesity across the sodium intake assessments as evidenced by systematic reviews in adults. SUBJECTS/METHODS: A systematic search identified systematic reviews comparing the association of dietary sodium intakes with obesity-related outcomes such as body mass index (BMI), body weight, waist circumference, and risk of (abdominal) obesity. We searched PubMed on October 24, 2022. To assess the Risk of Bias in Systematic Reviews (ROBIS), we employed the ROBIS tool. RESULTS: This review included 3 systematic reviews, consisting of 39 unique observational studies (35 cross-sectional studies and 4 longitudinal studies) and 15 randomized controlled trials (RCTs). We found consistently positive associations between dietary sodium intake and obesity-related outcomes in cross-sectional studies. Studies that used 24-h urine collection indicated a greater BMI for those with higher sodium intake (mean difference = 2.27 kg/m2; 95% confidence interval [CI], 1.59-2.51; P < 0.001; I2 = 77%) compared to studies that used spot urine (mean difference = 1.34 kg/m2; 95% CI, 1.13-1.55; P < 0.001; I2 = 95%) and dietary methods (mean difference = 0.85 kg/m2; 95% CI, 0.1-1.51; P < 0.05; I2 = 95%). CONCLUSIONS: Quantitative synthesis of the systematic reviews has shown that cross-sectional associations between dietary sodium intake and obesity outcomes were substantially different across the sodium intake assessments. We need more high-quality prospective cohort studies and RCTs using 24-h urine collection to examine the causal effects of sodium intake on obesity.

Effect of tranexamic acid on blood loss reduction in patients undergoing orthognathic surgery under hypotensive anesthesia: a single-center, retrospective, observational study

  • Keisuke Harada;Noritaka Imamachi;Yuhei Matsuda;Masato Hirabayashi;Yoji Saito;Takahiro Kanno
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.50 no.2
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    • pp.86-93
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    • 2024
  • Objectives: Orthognathic surgery is a surgical procedure performed by intraoral approach with established and safe techniques; however, excessive blood loss has been reported in rare cases. In response, investigative efforts to identify methods to reduce the amount of blood loss have been made. Among such methods, the administration of tranexamic acid was reported to reduce the amount of intraoperative blood loss. However, few studies to date have reported the effect of tranexamic acid in orthognathic surgery under hypotensive anesthesia. The present study aimed to investigate the effect of the administration of tranexamic acid on intraoperative blood loss in patients undergoing bimaxillary (maxillary and mandibular) orthognathic surgery under hypotensive anesthesia. Patients and Methods: A total of 156 patients (mean age, 27.0±10.8 years) who underwent bimaxillary orthognathic surgery under hypotensive anesthesia performed by the same surgeon between June 2013 and February 2022 were included in this study. The following data were collected from the medical records of each patient: background factors (age, sex, and body mass index), use of tranexamic acid, surgical procedures, previous medical history, duration of surgery, American Society of Anesthesiology physical status findings before surgery, intraoperative blood loss as a primary outcome, in-out balance, and blood test results. Descriptive statistics were calculated for statistical analysis, and a t-test and the chi-squared test were used for between-group comparisons. Group comparisons were performed after 1:1 propensity score matching to adjust for confounding factors. Statistical significance was set at P<0.05. Results: Comparison between the groups based on the use of tranexamic acid revealed a significant difference in operation time. Propensity score matching analysis revealed that intraoperative blood loss was significantly lower in the tranexamic acid group. Conclusion: The administration of tranexamic acid was effective in reducing intraoperative blood loss in patients undergoing bimaxillary orthognathic surgery under hypotensive anesthesia.

Lessons from constructing and operating the national ecological observatory network

  • Christopher McKay
    • Journal of Ecology and Environment
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    • v.47 no.4
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    • pp.187-192
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    • 2023
  • The United States (US) National Science Foundation's (NSF's) National Ecological Observatory Network (NEON) is a continental-scale observation facility, constructed and operated by Battelle, that collects long-term ecological data to better understand and forecast how US ecosystems are changing. All data and samples are collected using standardized methods at 81 field sites across the US and are freely and openly available through the NEON data portal, application programming interface (API), and the NEON Biorepository. NSF led a decade-long design process with the research community, including numerous workshops to inform the key features of NEON, culminating in a formal final design review with an expert panel in 2009. The NEON construction phase began in 2012 and was completed in May 2019, when the observatory began the full operations phase. Full operations are defined as all 81 NEON sites completely built and fully operational, with data being collected using instrumented and observational methods. The intent of the NSF is for NEON operations to continue over a 30-year period. Each challenge encountered, problem solved, and risk realized on NEON offers up lessons learned for constructing and operating distributed ecological data collection infrastructure and data networks. NEON's construction phase included offices, labs, towers, aquatic instrumentation, terrestrial sampling plots, permits, development and testing of the instrumentation and associated cyberinfrastructure, and the development of community-supported collection plans. Although colocation of some sites with existing research sites and use of mostly "off the shelf" instrumentation was part of the design, successful completion of the construction phase required the development of new technologies and software for collecting and processing the hundreds of samples and 5.6 billion data records a day produced across NEON. Continued operation of NEON involves reexamining the decisions made in the past and using the input of the scientific community to evolve, upgrade, and improve data collection and resiliency at the field sites. Successes to date include improvements in flexibility and resilience for aquatic infrastructure designs, improved engagement with the scientific community that uses NEON data, and enhanced methods to deal with obsolescence of the instrumentation and infrastructure across the observatory.

Factors Related to Perceived Health Status in Patients with Type 2 Diabetes (제2형 당뇨병 환자의 기능적 헬스 리터러시가 주관적 건강에 미치는 영향: 일개 대학병원 외래 환자를 대상으로)

  • Won, Ang Li;Yoo, Seung Hyun;You, Myoung Soon
    • Korean Journal of Health Education and Promotion
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    • v.31 no.3
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    • pp.1-13
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    • 2014
  • Objectives: This study was performed to identify factors related to perceived health status among patients with type 2 diabetes. Methods: This is cross-sectional observational study. Respondents were 106 visitors in an outpatient diabetes clinic of a university hospital. Self-report questionnaire which included general information inquiry, diabetes-related, sociopsychological factors, functional health literacy and perceived health status was used for this study. The data was analyzed by using descriptive statistics, independent simple t-test, one-way ANOVA, and hierarchical multiple linear regression. All analysis were conducted using SAS 9.3. Results: Among the respondents, 43.4% engaged in poorly perceived health status. After adjusting for control variables, functional health literacy is significantly related to perceived health status(${\beta}$=0.095, p=0.016). Conclusion: Independent of diabetes-related, sociopsychological factors, higher functional health literacy is associated with better perceived health status of patients with type 2 diabetes. In order to improve perceived health status in the type 2 diabetes patients, it is necessary to develop strategy to enhance the functional health literacy.

Defining the Patterns and Factors of Urban Crime in Korean Cities Based on the Analysis of Social Statistical Data

  • Chang, Dong-Kuk;Shim, Jae-Choon;Park, Joo-Hee
    • Architectural research
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    • v.14 no.2
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    • pp.45-56
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    • 2012
  • The high rate of urban crime is a main issue that needs to be dealt with in this high-tech society. With the rapid increase of urban crime, research has mainly focused on topics either on a global or a local scale, such as cities or communities and houses or buildings, without reliable observational data. This study makes the best use of the nationwide surveys carried out by Korean government agencies for the analysis of urban crime patterns and factors in major Korean cities. The aims of this research are threefold: understanding the relationship between urban crime patterns and socio-economic differences in cities, determining the effect of residence types on the urban crime patterns; and uncovering potential influential factors of a crime victim's individual characteristics. The statistical methods used for the analysis of social statistical data are as follows: simple regression, logistic regression, one-way ANOVA and post-hoc test. This research found that the patterns of urban crime rate in cities have a certain tendency toward the cities' socio-economic and geographical differences. The residence type is an influential factor showing a close relation to the crime rate. Personal issues, such as the types of occupation, education, marriage, etc., are directly relevant to victims of crime.

EFFECTS OF WAVE-PARTICLE INTERACTIONS ON DIFFUSIVE SHOCK ACCELERATION AT SUPERNOVA REMNANTS

  • Kang, Hyesung
    • Journal of The Korean Astronomical Society
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    • v.46 no.1
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    • pp.49-63
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    • 2013
  • Nonthermal radiation from supernova remnants (SNRs) provides observational evidence and constraints on the diffusive shock acceleration (DSA) hypothesis for the origins of Galactic cosmic rays (CRs). Recently it has been recognized that a variety of plasma wave-particle interactions operate at astrophysical shocks and the detailed outcomes of DSA are governed by their complex and nonlinear interrelationships. Here we calculate the energy spectra of CR protons and electrons accelerated at Type Ia SNRs, using time-dependent, DSA simulations with phenomenological models for magnetic field amplification due to CR streaming instabilities, Alf$\acute{e}$enic drift, and free escape boundary. We show that, if scattering centers drift with the Alf$\acute{e}$en speed in the amplified magnetic fields, the CR energy spectrum is steepened and the acceleration efficiency is significantly reduced at strong CR modified SNR shocks. Even with fast Afv$\acute{e}$nic drift, DSA can still be efficient enough to develop a substantial shock precursor due to CR pressure feedback and convert about 20-30% of the SN explosion energy into CRs. Since the high energy end of the CR proton spectrum is composed of the particles that are injected in the early stages, in order to predict nonthermal emissions, especially in X-ray and ${\gamma}-ray$ bands, it is important to follow the time dependent evolution of the shock dynamics, CR injection process, magnetic field amplification, and particle escape. Thus it is crucial to understand the details of these plasma interactions associated with collisionless shocks in successful modeling of nonlinear DSA.

Nursing Students' Lived Experiences of Attending LeBoyer Birth (간호학생의 르봐이예 분만참여 경험)

  • Kim, Mi-Jong
    • Women's Health Nursing
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    • v.18 no.1
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    • pp.62-73
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    • 2012
  • Purpose: The purpose of this study was to understand the lived experiences of nursing students' during Leboyer. Methods: Eleven senior nursing students were recruited from April to June in 2010. After completing informed consents, data were collected through in-depth interviews. All interviews were recorded and transcribed verbatim before analyzing. Nursing students were asked about their observational experiences during Leboyer births. Data were analyzed by using the Colaizzi style. Results: Interviews revealed 4 categories and 9 themes. The categories were: 'Respecting and blessing new baby', 'Keeping calm and joyful birth atmosphere', 'Reminding the meaning of nursing', 'Comparing Leboyer and convenience birth and making up their mind'. Conclusion: This study showed that observation of Leboyer birth is helpful for nursing students in order to have positive impression about childbirth. Furthermore, it is suggested that an exploration of the experiences of women and their husbands during Leboyer births would be helpful. On the basis of this study, it is concluded that the Leboyer birth, which focuses on baby's human right, should be introduced women's health nursing field as an effective birth strategy.