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Analysis of Trend of Studies on Microneedle Treatment System (MTS)

  • Chun, Hea-Sun;Song, Ho-Seub
    • Journal of Pharmacopuncture
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    • v.24 no.4
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    • pp.182-190
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    • 2021
  • Objectives: The purpose of this study was to analyze the microneedle therapy system (MTS) and its research methods for the past 10 years in Korea. Methods: Data on microneedle therapy system were collected using NDSL, KISS, RISS, and OASIS electronic databases from January 2010 to August 2021. "microneedle," "derma stamp," "microneedle therapy system" were used as the keywords. The present study, however, excluded data that were 1) unrelated to the microneedle therapy system, 2) from review/meta/protocol studies, and 3) from overseas studies. Data selected through the primary screening process, animal studies, case reports, and clinical data were included in the analysis. However, information data not related to the microneedle therapy system were excluded from the study. Results: Among the MTS-related papers published from January 2010 to August 2021, 7 animal research, 2 clinical trials, and 10 case studies were published. Based on the research topics, there were 8 papers on skin improvement and skin diseases, 7 papers on hair growth and hair loss, 3 papers on stability, and 1 paper on peripheral facial paralysis. Conclusion: Most of the studies related to MTS focused on skin, hair, and stability. The effect of MTS on hair growth and skin improvement has been confirmed, and it has been proven to have significant effects on the treatment of acne, acne scars, and hair loss in clinical practice. No serious side effects were observed during the MTS treatment, and the safety assessment confirmed that it was safe for use.

Study of Latest Trend on Acupuncture for Obesity Treatment

  • Chun, Hea-Sun;Kim, Dong-Hwan;Song, Ho-Seub
    • Journal of Pharmacopuncture
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    • v.24 no.4
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    • pp.173-181
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    • 2021
  • Objectives: The aim of this review was to appraise Korean studies published between 2010 and 2021 which examined the role of acupuncture in the treatment of obesity. Methods: We performed a search of the NDSL, KISS, RISS, OASIS, PubMed, EMBASE electronic databases for relevant animal researches, case reports, and clinical trials, using the following search terms: 'obesity', 'acupuncture', 'electroacupuncture', and 'pharmacopuncture'. We excluded previous reviews and meta-analyses, studies not related to obesity or acupuncture treatment, as well as studies conducted in countries other than Korea. We also excluded studies where relevant information on acupuncture treatment in obesity could not be obtained. Results: Most studies were conducted in animals, followed by case reports and clinical trials. In animal researches and case reports, pharmacopuncture was the most used intervention. In case studies, electroacupuncture, thread-embedding therapy, manual acupuncture, acupotomy, and auricular acupuncture were also used. In animal researches, pharmacopuncture treatment was associated with improvement in obesity indices. In the case of local obesity, specific acupuncture techniques such as thread-embedding therapy and pharmacopuncture were associated with significant improvements in local obesity, even when diet and exercise were not controlled for. Conclusion: Acupuncture treatment showed significant benefit in the treatment of obesity, with a local effect evident for certain approaches, such thread-embedding therapy and acupotomy.

A Systematic Review and Meta-Analysis of Manual Therapy for Neck Pain Caused by Traffic Accidents (교통사고로 인한 경항통에 적용한 수기요법의 효과: 체계적 고찰 및 메타분석)

  • Kang, Seok-Beom;Shon, Woo-Seok;Kim, Young-Jun;Woo, Chang-Hoon
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.16 no.2
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    • pp.21-28
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    • 2021
  • Objectives To investigate the effectiveness of manual therapy for neck pain caused by traffic accidents. Methods We searched six electronic databases (OASIS, KISS, RISS, NDSL, MEDLINE, and Cochrane Library) to gather randomized controlled trials using the keywords 'manual theray OR chuna OR tuina' and 'whiplash injury OR neck sprain'. Results Eight RCTs were selected based on the inclusion criteria. Four studies were meta-analyses. The systematic review found a positive effect of manual therapy for whiplash injury. All studies showed a high risk of performance bias. Conclusions The systematic review reported favorable results using manual therapy for neck pain caused by traffic accidents. However, this study has several limitations owing to the high risk of bias. Further clinical studies and the development of a study design are required for stronger evidence.

Indication Analysis Study through Literature Review of Clinical Trials on Visceral Chuna Manipulation (내장기추나요법 임상연구 문헌고찰을 통한 적응증 분석 연구)

  • Sul, Jae-Uk;Lee, Jin-Hyun;Jo, Dong Chan;Hwang, Man-Suk
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.16 no.2
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    • pp.107-116
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    • 2021
  • Objectives The purpose of this study is to analyze the trend and indication of clinical research about Visceral Chuna Manipulation and to suggest the direction of further study. Methods We searched 9 electronic databases (MEDLINE Pubmed, EMBASE, CENTRAL, CiNii, CNKI, KMbase, OASIS, NDSL, KISS) using the search terms "visceral manipulation", "visceral manual therapy" and identified relevant literature that investigated visceral manipulation as a intervention for various subjects. Results Among 142 studies were searched and screened, 16 met designated criteria. Visceral Chuna Manipulation showed the effectiveness in musculoskeletal disease, digestive disease, psychiatry, obstetrics, circulatory and oncology. Conclusions This study shows possibility of Visceral Chuna Manipulation as a treatment for many diseases. Better designed further study is necessary to establish the evidence of clinical efficacy of visceral manipulation and to suggest standard of techniques and treatment protocols for diverse patients.

Analysis of Safety of Mahuang in Studies for Treatment of Obesity (비만 치료 연구에서 마황의 안전성 분석)

  • Cho, Minjin;Kim, Sungha;Kim, Hojun;Song, Mi Young
    • Journal of Korean Medicine for Obesity Research
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    • v.21 no.2
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    • pp.95-104
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    • 2021
  • Objectives: The purpose of this study is to analyze the adverse events and safety of Mahuang used as anti-obesity treatment in Korean medicine. Methods: PubMed, EMBASE, Cochrane, KoreaMed, Oriental Medicine Advanced Searching Integrated System (OASIS) and SCIENCE-ON were used as searching for randomized controlled trials investigating the safety of Mahuang for treating obesity from January, 2000 to July, 2021. Results: Total 6 studies were included for analyzing. In most studies, heart rate was higher in experimental group than in placebo group with statistically significant difference. Both systolic and diastolic blood pressure had no significant differences between both groups, but systolic blood pressure got lower in experimental group. Most adverse events reported in experimental group were dry mouth, constipation, diarrhea, palpitation and insomnia, but serious adverse events were not reported. Conclusions: This study provides the evidence about the safety of Mahuang for treating obesity. However, increase of heart rate and minor adverse events could be occurred. Further study is needed to confirm the safety of Mahuang.

Chuna Manual Therapy for Lateral Epicondylitis: A Systematic Review (외측상과염의 추나 치료에 대한 체계적 문헌 고찰)

  • Han, Dayoung;Lee, Jiyoon;Nam, Suhyun;Son, Jungmin;Jung, Dahae;Jo, Hyemi
    • Journal of Korean Medicine Rehabilitation
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    • v.32 no.3
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    • pp.65-75
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    • 2022
  • Objectives This study was conducted to analyze the therapeutic effect of Chuna therapy for lateral epicondylitis. Methods Key words such as lateral epicondylitis and Chuna were searched in 10 databases (National Digital Science Library [NDSL], Oriental Medicine Advanced Searching Integrated System [OASIS], Research Information Sharing Service [RISS], Koreanstudies Information Service [KISS], KMBASE, Cochrane Library, PubMed, EMBASE, J-STAGE, China Academic Jurnals [CAJ]), and only suitable randomized controlled trials (RCTs) were selected. Results 8 RCTs were finally selected, and Chuna therapy showed positive results for lateral epicondylitis compared to western medicine, acupuncture, warm-acupuncture and Chinese medicine iontophoresis. Conclusions In this study, we finally reviewed 8 studies about Chuna therpay used for lateral epicondylitis. The studies showed that Chuna therapy is effective in treating lateral epicondylitis. However, because all of selected studies were found in Chinese database, more high-quality clinical trials about Chuna therapy for lateral epicondylitis are needed in Korea.

A Clinical Analysis to Study Effectiveness of Korean Medicine for Medial Collateral Ligament Injury of the Knee (무릎 내측측부인대 손상의 한의학적 치료에 대한 국내외 임상연구 동향 분석)

  • Oh, Tae Young;Han, Si Hoon;Oh, Min Seok
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.17 no.1
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    • pp.35-46
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    • 2022
  • Objectives This study aimed to review clinical studies on traditional Korean medicine treatment for medial collateral ligament injury of the knee. Methods Clinical studies on Korean traditional medicine treatment of medial collateral ligament injury were conducted. We used five Korean online databases (OASIS, KISS, RISS, DBPia, and ScienceOn) and three foreign databases (PubMed, Cochrane Library, and CNKI). Out of 99 studies that were found, we excluded repeated articles, studies that were not related to Korean medicine, and those not relevant to the topic of the study. Results Ten randomized controlled trials and 20 case studies were selected. Eight traditional Korean medicine treatments, including acupuncture, herbal medicine, chuna, and herbal ointment, were used in these studies. The most commonly used treatment was found to be acupuncture. Conclusions Our study showed that traditional Korean medicine for medial collateral ligament injuries was effective. However, there were some limitations. Further clinical studies and randomized controlled clinical trials are needed for more evidence on Korean traditional medicine.

Intravaginal Administration of Oriental Medicine on Vaginal Atrophy in Menopause : A Systemic Review (폐경기 질 위축에 대한 한약제제 질 내 투여의 효과 : 체계적 문헌 고찰)

  • Lee, Soo-Hyung;Jung, Hyun-Tae;Kim, Song-Baek
    • The Journal of Korean Obstetrics and Gynecology
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    • v.34 no.2
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    • pp.62-81
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    • 2021
  • Objectives: The purpose of this study is to review clinical studies and evaluate effectiveness of intravaginal administration of oriental medicine on vaginal atrophy in menopausal women. Methods: 'postmenopause', 'menopause', 'vaginal atrophy', 'atrophic vaginitis', 'vaginal cream', 'vaginal gel', 'pessary', 'suppository' were searched on 3 online databases (Pubmed, Cochrane Library, OASIS). The risk of bias was assessed by using Cochrane risk of bias (RoB) 2.0 tool. Results: 9 randominized controlled trials (RCTs) were selected among 489 articles. The types of intervention were intravaginal administration of oriental medicine. 6 studies showed that treatment group was better than placebo control group or both treatment group and western medicine control group improved similarly. 2 studies were not significant effective in some results and 1 study was not statistically significant. Conclusions: Intravaginal administration of oriental medicine can be an effective option in treating menopausal women with vaginal atrophy. but considering the small number and low quality of studies, further well-designed studies are needed to confirm the effectiveness of this treatment.

Complementary and Alternative Medicine for treating Low Back Pain with Teaching Exercise: A narrative review

  • Kim, Yeonhak;Yang, Gi-Young
    • The Journal of Korean Medicine
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    • v.41 no.4
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    • pp.78-87
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    • 2020
  • Objectives: In modern society, many people have low back pain (LBP) and spinal diseases. About 80% of them experience severe LBP more than once in their lifetime. We can find studies on many Korean medicine-based treatments, such as acupuncture treatment for LBP and exercise therapy, which are effective in reducing the symptoms. This study focuses on the combined effect of both Korean medicine and exercise therapy for treating LBP. Method: For this review, we searched for articles focusing on pain and disability recovery in pre-clinical and clinical studies of extension and flexion exercise therapy related to LBP. The search databases were as follows: PubMed, Google Scholar, and seven Korean electronic databases (Korea Citation Index (KCI), Korean studies Information Service System (KISS), Research Information Service System (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), DBPIA, National Digital Science Library (NDSL), and KOREAMED). The keywords were as follows: Korean Medicine, back pain, flexion exercise, extension exercise, McKenzie method, McKenzie exercise, Williams' flexion exercise, and Mechanical Diagnosis and Therapy. Results & Conclusions: This review shows the usefulness of flexion and extension exercises for LBP treatment and effective patient education, but further studies are necessary.

A Literature Review of Treatments of Stomatitis in Korean Medicine (구내염의 한방 치료에 대한 문헌 고찰)

  • Yu-Ra Im;Ho-Jun Jeong
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.36 no.1
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    • pp.110-123
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    • 2023
  • Objectives : The purpose of this study is to investigate the treatments of Stomatitis in Korean medicine. Methods : We reviewed domestic journals through databases on RISS, KISS, OASIS, KISTI to search case reports and follow-up studies about 'Stomatitis' and '口瘡' using the terms with 'Korean medicine' or 'Korean medicine treatment'. Also, we used CNKI to find Randomized controlled trials(RCTs) from Chinese journals by using the term '口腔炎'. Results : A total of 16 articles were searched. Those of 7 are case report, 2 are follow-up study, 7 are RCTs. The way to treat stomatitis were through using herb medicine, acupuncture, electro-acupuncture, herbal acupuncture, external preparation, indirect moxibustion and so on. All papers reported that after Korean medicine treatment, symptoms of stomatitis are relieved. Conclusions : According to these journals, Korean medicine is helpful to treat Stomatitis. In the future, more clinical studies are needed to establish the foundation of Korean medicine to treat stomatitis.