• 만화애니메이션 연구
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• 통권16호
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• pp.257-272
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• 2009

이 논문에서는 알폰소 쿠아론 감독의 <위대한 유산>을 찰스 디킨스의 원작과 데이비드 린 감독의 같은 원작을 영화한 작품과의 비교 속에서 분석하였다. 고전 소설을 영화한 작품을 평가하는데 있어서 고려되어야 할 점은 원작에 대한 충실도 외에 문학과 영화 형식의 차이점, 당대 관객들의 기호, 그리고 감독 자신의 해석이 고려되어야한다. 이러한 기준으로 볼 때 데이비드 린은 원작에 충실하면서 미장센을 통해서 자신의 해석을 훌륭하게 표현하였고 알폰소 쿠아론은 원작을 할리우드 고전적 문법아래 과감하게 변형한 후 현대적인 영화 형식을 구가함으로써 완성도 있고 대중 친화적인 작품을 만드는데 성공하였다.

• Journal of Genetic Medicine
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• 제14권2호
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• pp.80-85
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• 2017

Methylmalonic acidemia (MMA) is an autosomal recessive metabolic disorder characterized by an abnormal accumulation of methylmalonyl-CoA and methylmalonate in body fluids without hyperhomocysteinemia. Cardiac disease is a rarely known lethal complication of MMA, herein, we report a Korean neonate diagnosed with MMA on the basis of biochemical and genetic findings, who developed cardiomyopathy, resulting in sudden death. The patient presented vomiting and lethargy at 3 days of age. Initially, the patient had an increased plasma propionylcarnitine/acetylcarnitine concentration ratio of 0.49 in a tandem mass spectrometry analysis and an elevated ammonia level of $537{\mu}mol/L$. Urine organic acid analysis showed increased excretion of methylmalonate. Subsequent sequence analysis of the methylmalonyl-CoA mutase (MUT) gene revealed compound heterozygous mutations c.323G>A (p.Arg108His) in exon 1 and c.1033_1034del (p. Leu345Serfs*15) in exon 4, the latter being a novel mutation. In summary, this is the first case of MMA and cardiomyopathy in Korea that was confirmed by genetic analysis to involve a novel MUT mutation.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 추계학술대회
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• pp.600-603
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• 2018

본 연구에서는 Novel Engineering 교수학습단계를 기반으로 창의적 체험활동 시간에 이루어지는 SW 융합형 호국보훈 수업 방안에 대해 기술하고자 한다. 글짓기, 그림 그리기 등 천편일률적으로 이루어지는 호국보훈 수업에 새로운 교육 방법인 Novel Engineering을 적용한 SW 융합형 수업을 개발함으로써 학생들의 컴퓨팅 사고력을 바탕으로 하는 문제해결력 신장은 물론 나라 사랑 정신을 함양할 수 있다. 순국열사의 이야기를 담은 도서를 읽고, 책 속에 제시된 역사적 장면을 추체험활동(Re-enactment)을 통해 시나리오로 작성한 후 이를 Lego WeDo 2.0을 활용해 시뮬레이션 상황을 구현한다. 이러한 SW 융합형 호국보훈 수업을 통해 학생들의 변화도를 창의적 사고력 검사지와 설문지를 통해 분석한 결과 유의미한 변화가 있음을 알 수 있었다. 향후에는 보다 다양한 학년과 교과로 그 범위를 확대하여 Novel Engineering을 적용한 SW 융합형 수업의 효과성을 일반화할 수 있도록 해야겠다.

• Journal of Ship and Ocean Technology
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• 제3권3호
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• pp.13-24
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• 1999

In this paper, a 2-dimensional novel beam element is developed and a method to replace the 3-dimensional analysis with 2-dimensional analysis is proposed. The developed novel beam element named rigid-ended beam element can consider the effect of three kinds of span points within one element, which was impossible in modeling with the ordinary beam element. Calculated results for the portal frame using the rigid-ended beam element agree with the results using membrane element. And also, the proposed simplified 3- dimensional analysis method which includes two step analysis using influence coefficients shows good accuracy. Structural analysis using the rigid-ended beam element and the simplified 3-dimensional method is revealed to have good computing efficiency due to unnecessity of the elements corresponding to the brackets and simplification of 3-dimensional analysis.

• BMB Reports
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• 제32권5호
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• pp.497-501
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• 1999

Biotinylation of recombinant proteins is a powerful tool for the detection and analysis of proteins of interest in a large variety of assay systems. The recent development of in vivo biotinylation techniques in E. coli has opened new possibilities for the production of site-specifically biotinylated proteins without the need for further manipulation after the isolation of the recombinantly expressed proteins. In the present study, a novel vector set was generated which allows the convenient cloning and expression of proteins of interest fused with an N-terminal in vivo biotinylated thioredoxin (TRX) protein. These vectors were derived from the previously reported pBIOTRX vector into which was incorporated part of the pBluescript II+phagemid multiple cloning site (MCS), amplified by PCR using a pair of sophisticated oligonucleotide primers. The functionality of these novel vectors was examined in this system by recombinant expression of rat transforming growth factor-$\beta$. Western-blot analysis using TRX-specific antibodies or peroxidase-conjugated streptavidin confirmed the successful induction of the fusion protein and the in vivo conjugation of biotin molecules, respectively. The convenience of molecular subcloning provided by the MCS and the effective in vivo biotinylation of proteins of interest makes this novel vector set an interesting alternative for the production of biotinylated proteins.

• 한국미생물생명공학회:학술대회논문집
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• 한국미생물생명공학회 2000년도 Proceedings of 2000 KSAM International Symposium and Spring Meeting
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• pp.128-134
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• 2000

In the course of flora analysis of soil Archaea, we found very strange 16S rDNA clones, which could possibly constitute a sister clade from known two archael, Crenarchaeota and Euryarchaeota, lineages. Overall signature sequences showed that the clones were closely related to domains Archaea and Eucarya. However, at least nine nucleotides distinguished the novel clones from domains Archaea and Eucarya. Phylogenetic trees drawn by maximum parsimony, neighbor joining and maximum likelihood methods also showed unique phylogenetic position of the clones. A very specific primer set was synthesized to detect the presence of the novel group of organisms in terrestrial environments. A specific DNA fragment was amplified from all of paddy soil DNAs, and this fact suggests that the novel organisms inhabit paddy soils.

• Journal of Power Electronics
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• 제16권3호
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• pp.1141-1151
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• 2016

This study proposes a novel islanding detection method for distributed photovoltaic (PV) systems with multi-inverters based on a combination of the power line carrier communication and Sandia frequency shift islanding detection methods. A parameter design method is provided for the novel scheme. On the basis of the designed parameters, the effect of frequency measurement errors and grid line impedance on the islanding detection performance of PV systems is analyzed. Experimental results show that the theoretical analysis is correct and that the novel method with the designed parameters has little effect on the power quality of the inverter output current. Non-detection zones are not observed, and a high degree of reliability is achieved. Moreover, the proposed islanding detection method is suitable for distributed PV systems with multi-inverters.

• 한국식품과학회지
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• 제29권6호
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• pp.1304-1308
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• 1997

충치 예방물질의 지속적인 연구로 Jack Fruit 잎으로부터 새로운 procyanidin류를 분리하였고 thiolysis 및 기기 분석에 의해 구조를 결정하였다. 신규화합물의 화학 구조는 flavan-3-ol 화합물의 삼량체인 $(-)-epiafzele-chin-(4{\beta}{\rightaroow}8)-afzelechin-(4{\alpha}{\rightaroow}8)-catechin$의 구조로, 분자량이 $833\;[M-H]^-$ 이었다. 화학 구조가 결정된 신규화합물의 glucosyltransferase저해 실험 결과 1.0 mM에서 완벽한 저해 효과가 관찰되었고 저해기작은 비경쟁적 저해제임을 알았다.

• 미국학
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• 제44권2호
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• pp.211-229
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• 2021

Toni Morrison's A Mercy (2008) describes Jacob Vaark, an early settler from England, and his grand house that symbolizes the American Dream in the 1680s. The source of his success is colonialism and slavery, as revealed by four female characters-a white Englishwoman Rebekka and three non-white women Florens, Sorrow, and Lina. Analyzing how the novel compares the women's experiences with nature and natural objects, this paper draws on ecofeminism as a theoretical frame of analysis to examine the novel's hitherto overlooked representations of naturalized women and feminized nature. The paper analyzes how the novel represents oppressions and exploitations of the four women in relation to nature that is similarly appropriated and developed by European men. The paper maintains that the novel does not represent these "naturalized" women as powerless and passive but portrays them as growing characters who resist patriarchy, colonialism, and capitalism.

• International journal of advanced smart convergence
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• 제11권1호
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• pp.36-41
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• 2022

Recently, to improve the performance of the strongest channel gain user in non-orthogonal multiple access (NOMA) with a non-uniform source and symmetric superposition coding (SSC), a novel bit-to-symbol (BTS) mapping have been proposed. However, only the performance of the user with the stronger channel gain was analyzed. Thus, we compare the bit-error rate (BER) of the new BTS scheme with that of uniform sources, especially for the user with weakest channel gain. First, we show that the performance of the novel BTS scheme for the user with weakest channel gain also improves, compared to that of the uniform sources. Furthermore, the signal-to-noise (SNR) gain of the new BTS scheme over the uniform sourcesis calculated. As a consequence, the novel BTS scheme would improve the performance of the user with weakest channel gain as well as that with the stronger channel gain for SSC NOMA with a non-uniform source.