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Effect of Oral Immunization with Liposome-Entrapped Bacterial Antigen on Protection Against Experimental Aeromonas Hydrophila

  • Choi, Sang-Hoon;Oh, Chan-Ho
    • Animal cells and systems
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    • v.11 no.1
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    • pp.33-38
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    • 2007
  • Liposome-entrapped atypical Aeromonas hydrophila antigen was prepared to investigate the potential protective efficacy for A. hydrophila infection. Carp (Cyprinus carpio) were immunized orally with liposome-entrapped A. hydrophila antigen. After immunization, significantly more antigen-specific antibodies were detected in serum, intestinal mucus and bile than non-immunized control group. The immunized carp were then challenged by immersion with $1{\times}10^{6}$ cfu/ml of A. hyrdophila for 60 min. Of the eight non-immunized carp, three carp died (62.5% survival), whereas five out of six (83.5%) of the immunized survived. Furthermore, development of skin ulcers was significantly inhibited in carp immunized with liposomes containing A. hydrophila antigen. These results suggest that liposomes containing A. hydrophila antigen have a potential for induction of protective immune responses against atypical A. hydrophila infection and also suggest the possibility of developing a vaccine that may ultimately be used for prevention of fish diseases.

A study on the Application of Inorganic Reinforced Non-Flammable Molding to Building Exterior (무기계보강 CLC 불연몰딩의 건축물 외벽적용 연구)

  • Kwon, Hae-Won;Gong, Min-Ho;Lee, Chang-Woo;Choi, Byung-Cheol
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2021.05a
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    • pp.61-62
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    • 2021
  • Exterior wall molding, which is widely applied as a design element of the exterior wall of domestic apartment, should be applied as a nonflammable or semi-nonflammable material grade according to the rules on standards for evacuation/fire protection structures of buildings. For this reason, stone and AL sheet are mainly used, but stone is expensive and design autonomy is low. Inorganic reinforced CLC nonflammable molding was applied to the exterior wall of the building through tests of nonflammable performance, noise reduction, and installation stability.

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The Effects of IDS(Indongsoyeom-bang) Treatment on the Hematological and Cytopathological Alterations in Non-Bacterial Prostatitis Rat Model (인동소염방(忍冬消炎方)이 만성 비세균성 전립선염 Rat 모델에서 혈액 및 세포조직의 변화에 미치는 영향)

  • Lee, Jong-Bin;Hwang, Seock-Yeon;Cho, Chung-Sik
    • Journal of Haehwa Medicine
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    • v.20 no.1
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    • pp.91-104
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    • 2011
  • Background : Although chronic non-bacterial prostatitis is increasing, it is hard to treat effectively. In western medicine, antimicrobials drug, ${\alpha}$-adreno-ceptor antagonists, anti-inflammatory drugs, tricyclic antidepressants and anticholinergic agents are used commonly, but chronic prostatitis/chronic pelvic pain syndromes is confusing and frustrating for urologist. IDS(Indongsoyeom-bang) is used in treatment of chronic prostatitis/chronic pelvic pain syndromes. And it is reported that GLS(Gleditsiae spina) and TOF(Toosendan fructus) components of IDS have significant effect on protection of the glandular epithelial cells. Objective : In this study was conducted to investigate the therapeutic effects and action machanism of IDS in the rat model of non-bacterial prostatitis induced by castration and testosterone treatment. Methods : We observed six experimental objects of normal group, control group, testosterone group, and IDS 50 mg/kg, 200mg/kg, 400mg/kg group. Rats were treated with 17 ${\beta}$-estradiol after castration for induction of experimental non-bacterial prostatitis, which is similar to human chronic prostatitis in histophatological profiles. IDS and testosterone were administered as an experimental specimen and a positive control, respectively. The prostates were evaluated by histological parameters including the epithelial score and epithelio-stromal ratio for glandular damage. Also, the prostates were observed by Hematological alterations of WBC, RBC, hemoglobin and platelet. Results : While prostates of control rats revealed severe acinar gland atrophy and stromal proliferation, the rats treated with IDS-50 showed a diminished range of the tissue damage. Epithelial score was improved in IDS than that of the control. The epithelio-stromal ratio was lower in IDS when compared to that of the control. Also, the examination of bloods were not observed hematological change. Conclusion : These finding suggests that IDS may protects the glandular epithelial cells. We concluded that IDS could be a useful remedy agent for treating chronic non-bacterial prostatitis.

Analysis on the Donators' Characteristics of Government-dominant and Non-governmental Food Bank Programs (정부주도형 및 민간주도형 푸드뱅크(Food Bank) 사업의 기탁 특성 분석)

  • Jo, Mi-Na;Hong, Min-Ah;Kang, Hye-Seung;Yang, Il-Sun
    • Korean Journal of Community Nutrition
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    • v.11 no.5
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    • pp.618-628
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    • 2006
  • The purpose of this study was to examine the donators' characteristics and donative foods of both government-dominant and non-governmental food bank program, to understand the problems and benefits of food bank program, and to find the solutions to activate food bank program. The questionnaires were distributed to 120 food bank operators and 3 donators were selected from each food bank for the survey from April 2002 to May 2002. 118 sheets (32.8%) from government-dominant food bank and 53 sheets (20.1%) from non-governmental food bank were collected. The main results of this study were as follows: The largest donators to either government-dominant or non-governmental food bank programs were bakery and confectionery companies 31.4% and 45.3% respectively. The majority of donated foods were 'goods in stock' (55.6%) and frequency of donation were largely on a daily basis (27.1% for government-dominant and 22.6% for non-governmental). Some of the donators who had more donative food did not donate, and the reasons were closeness to expiration date of food (67.3%), lack of legal protection in the event of food poisoning (54.5%), and poor public image of food related accidents (52.3%).

Islanding Detection for Grid-connected PV Inverter under Parallel Operation (계통연계형 태양광 인버터 병렬운전 상황에서의 단독운전 검출)

  • Jo, Yeong-Min;Kim, Dong-Gyun;Song, Seung-Ho;Choy, Ick;Lee, Young-Kwoun;Cho, Sang-Yoon;Choi, Ju-Yeop
    • The Transactions of the Korean Institute of Power Electronics
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    • v.21 no.4
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    • pp.283-289
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    • 2016
  • Islanding protection of a grid-connected photovoltaic (PV) inverter is a key function for standards compliance. Unintentional islanding results in safety hazards, reliability, and many other issues. Therefore, many anti-islanding schemes have been examined. However, existing anti-islanding schemes have poor power quality and non-detection zone issues. Moreover, most schemes have problems that deteriorate the performance of islanding detection under parallel operation. Therefore, this paper proposes a novel anti-islanding scheme that has negligible power quality degradation and has no non-detection zone and islanding detection under a parallel operation. Both simulation and experimental results validate the proposed scheme.

Compensation algorithm of a voltage transformer considering hysteresis characteristics (히스테리시스 특성을 고려한 전압 변성기 오차 보상 알고리즘)

  • Kang, Yong-Cheol;Zheng, Tai-Ying;Park, Jong-Min;Jang, Sung-Il;Kim, Yong-Guen
    • Proceedings of the KIEE Conference
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    • 2007.11b
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    • pp.12-14
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    • 2007
  • A voltage transformer (VT) is used to transform a high voltage into a low voltage as an input for a metering device or a protection relay. VTs use an iron core which maximizes the flux linkage. The primary current of the VT has non-fundamental components caused by the hysteresis characteristics of the iron core. It causes a voltage drop in the winding impedances resulting in the error of the VT. This paper describes a compensation algorithm for the VT. The proposed algorithm can compensate the secondary voltage of VT by calculating the primary current from the exciting current of the hysteresis loop in the voltage transformer. In this paper, the exciting branch was divided into a non-linear core loss resistor and a non-linear magnetizing inductor. The performance of the proposed algorithm was validated under various conditions using EMTP generated data. Test results show that the proposed compensation algorithm can improve the accuracy of the VT significantly.

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Characteristics and Application of the Highly-Durable and Highly-Sensitive Super Hydrophobic Acid-gas Sensing Dye (고내구성 고감도 강산감지기능 초소수성 색소의 특성 및 응용)

  • Kim, Taekyeong;Lee, Seonae
    • Textile Coloration and Finishing
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    • v.27 no.2
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    • pp.105-112
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    • 2015
  • In order to detect gas phase strong acid on fabrics, a hexyl-substituted monoazo yellow dye, which was the modified form of a conventional pH-indicating dye, Methyl Yellow, was studied in view of acid-gas sensing properties and its fastness. The dye was printed on polypropylene non-wovens for protective coveralls and examined under various conditions of strong acid such as hydrochloric acid. The dye showed color change from yellow to red on exposure to gas phase hydrochloric acid as low concentration as 1~3 ppm very instantly. Considering reuse of the dye-printed non-wovens, the repeatability of color change was tested on the same sample for 50 repeats and 100 days. The acid-gas sensing function was maintained almost the same level of initial performance. The color fastness of the dye on polypropylene non-wovens was very good showing higher than ratings 4 except for 3~4 to rubbing under wet condition.

Breast-Feeding Protects Infantile Diarrhea Caused by Intestinal Protozoan Infections

  • Abdel-Hafeez, Ekhlas Hamed;Belal, Usama Salah;Abdellatif, Manal Zaki Mohamed;Naoi, Koji;Norose, Kazumi
    • Parasites, Hosts and Diseases
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    • v.51 no.5
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    • pp.519-524
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    • 2013
  • This study investigated the effect of breast-feeding in protection against protozoan infection in infants with persistent diarrhea. Infants were classified into 2 groups; 161 breast-fed infants and the same number of non-breast-fed infants. Microscopic examinations of stool were done for detection of parasites and measuring the intensity of infection. Moreover, serum levels of IgE and TNF-${\alpha}$ were measured by ELISA. Cryptosporidium spp., Entamoeba histolytica/Entamoeba dispar, Giardia lamblia, and Blastocystis sp. were demonstrated in infants with persistent diarrhea. The percentage of protozoan infections was significantly lower in breast-fed infants than that in the non-breast-fed infants. The levels of IgE and TNF-${\alpha}$ were significantly lower in the breast-fed group than in the non-breast-fed group. There were significant positive associations between the serum levels of IgE and TNF-${\alpha}$ and the intensity of parasite infection in the breast-fed group. It is suggested that breast-feeding has an attenuating effect on the rate and intensity of parasite infection.

Non-linear aero-elastic response of a multi-layer TPS

  • Pasolini, P.;Dowell, E.H.;Rosa, S. De;Franco, F.;Savino, R.
    • Advances in aircraft and spacecraft science
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    • v.4 no.4
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    • pp.449-465
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    • 2017
  • The aim of the present work is to present a computational study of the non-linear aero-elastic behavior of a multi-layered Thermal Protection System (TPS). The severity of atmospheric re-entry conditions is due to the combination of high temperatures, high pressures and high velocities, and thus the aero-elastic behavior of flexible structures can be difficult to assess. In order to validate the specific computational model and the overall strategy for structural and aerodynamics analyses of flexible structures, the simplified TPS sample tested in the 8' High Temperature Tunnel (HTT) at NASA LaRC has been selected as a baseline for the validation of the present work. The von $K{\acute{a}}rm{\acute{a}}n^{\prime}s$ three dimensional large deflection theory for the structure and a hybrid Raleigh-Ritz-Galerkin approach, combined with the first order Piston Theory to describe the aerodynamic flow, have been used to derive the equations of motion. The paper shows that a good description of the physical behavior of the fabric is possible with the proposed approach. The model is further applied to investigate structural and aero-elastic influence of the number of the layers and the stitching pattern.

"Peaceful Uses" of Outer Space and Japan' s Space Policy

  • Takai, Susumu
    • The Korean Journal of Air & Space Law and Policy
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    • no.spc
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    • pp.247-270
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    • 2007
  • Space development and utilization must be conducted within a framework of "peaceful uses" principle under Space Treaty. Japan ratified the treaty in 1967, and interpreted "peaceful uses" as "non-military uses" then. A ghost of "peaceful uses" principle has been hung over Japan up to the moment. Japan's space development and utilization has been conducted with genuine academic interest, and therefore Japan did not introduce space infrastructures to national security policy and did not facilitate growth of space industry. When the Cold War ended, Northeast Asian security environment makes Japan difficult to maintain an interpretation as "non-military uses". Besides the change of external security environment, the domestic industry situation and a series of rocket launching failure needed reexamination of Japan's space policy. Japan is gradually changing its space policy, and introducing space infrastructure in a national security policy under a "generalization" theory that gave a broad interpretation of "peaceful uses" principle. Council for Science and Technology Policy (CSTP) adopted a basic strategy of Japan's space policy in 2004. Since then, a long-term report of Japan Aerospace Exploration Agency (JAXA), an investigation report of Society of Japanese Aerospace Companies (SJAC) and a proposal of Japan Business Federation (JSF) were followed. Japan will promote space development and utilization in national security policy with a "strictly defensive defense" strategy and "non-aggressive uses"principle for protection of life and property of Japanese people and stabilization of East Asian countries.

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