• Korean Journal of Acupuncture
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• 제30권2호
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• pp.135-142
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• 2013

목적 : 본 연구는 노년층의 여성에게 신맥(BL62), 조해(KI6)혈에 대한 저주파자극이 뇌파에 어떠한 영향을 미치는지 알아보고 뇌 기능을 개선하는데 비화학적이고 비침습적인 자극 방법의 후보로써 가능성을 탐구해보고자 실시된 탐색적 연구이다. 방법 : 31명의 건강한 여성 피험자(평균연령, 54.5세)를 대상으로 이중맹검 무작위배정 임상연구가 12세션동안 실시되었다. 시험군에서는 감지할 수 없는 최대의 저주파자극이 실시되었으며(평균전류량, $0.04{\mu}A$), 대조군에서는 거짓자극이 실시되었다. 결과분석을 위해 12세션을 전후로 배경뇌파가 측정되었다. 결과 : 12세션의 자극이 실시된 후 대조군에 비해 실험군의 알파파 상대값은 11채널에서 유의한 증가를 보였으며(p<0.05), 감마파의 상대값은 7채널에서, 세타파의 상대값은 10채널에서 유의한 감소를 보였다. 결론 : 발목관절에 있는 신맥(BL62), 조해(KI6)혈에 대한 저주파 자극은 노년의 여성의 뇌에 베타, 세타, 감마파의 감소를 일으키는 반면 알파파를 선택적으로 증가시켜 뇌를 안정시키는 효과가 있는 것으로 보인다. 이러한 결과는 저주파자극이 향후 스트레스와 관련된 인지 문제를 치료하는 비침습적이고 비화학적인 도구로써의 가능성을 제공할 수 있을 것으로 보이며, 그 기전에 대한 추가적 연구가 필요할 것으로 보인다.

• Journal of Yeungnam Medical Science
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• 제34권2호
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• pp.191-199
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• 2017

Background: This study was conducted to provide a comparison between the clinical outcomes of primary percutaneous coronary intervention (PCI) and that of fibrinolysis followed by routine invasive treatment in ST elevation myocardial infarction (STEMI). Methods: A total of 184 consecutive STEMI patients who underwent primary PCI or fibrinolysis followed by a routine invasive therapy were enrolled from 2004 to 2011, and their major adverse cardiovascular events (MACEs) were compared. Results: Among the 184 patients, 146 patients received primary PCI and 38 patients received fibrinolysis. The baseline clinical characteristics were similar between both groups, except for triglyceride level ($68.1{\pm}66.62$ vs. $141.6{\pm}154.3mg/dL$, p=0.007) and high density lipoprotein level ($44.6{\pm}10.3$ vs. $39.5{\pm}8.1mg/dL$, p=0.005). The initial creatine kinase-MB level was higher in the primary PCI group ($71.5{\pm}114.2$ vs. $35.9{\pm}59.9ng/mL$, p=0.010). The proportion of pre-thrombolysis in MI 0 to 2 flow lesions (92.9% vs. 73.0%, p<0.001) was higher and glycoprotein IIb/IIIa inhibitors were administered more frequently in the primary PCI group. There was no difference in the 12-month clinical outcomes, including all-cause mortality (9.9% vs. 8.8%, p=0.896), cardiac death (7.8% vs. 5.9%, p=0.845), non-fatal MI (1.4% vs. 2.9%, p=0.539), target lesion revascularization (5.7% vs. 2.9%, p=0.517), and stroke (0% vs. 0%). The MACEs free survival rate was similar for both groups (odds ratio, 0.792; 95% confidence interval, 0.317-1.980; p=0.618). The clinical outcome of thrombolysis was not inferior, even when compared with primary PCI performed within 90 minutes. Conclusion: Early fibrinolysis with optimal antiplatelet and antithrombotic therapy followed by appropriate invasive procedure would be a comparable alternative to treatment of MI, especially in cases of shorter-symptom-to-door time.

• 한국산학기술학회논문지
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• 제20권7호
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• pp.151-157
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• 2019

최근 비침투 또는 비접촉 방식을 활용한 호흡상태 관찰에 대한 관심이 높아지고 있다. 여러 가지 많은 생체신호들 중 호흡신호를 활용하여 건강상태를 점검하는 것은 비정상적인 건강 상태에 대한 신속한 대응을 가능하게 해 준다. 본 논문에서는 국소 퓨리에 변환을 활용한 실시간 무호흡 상태 검출에 대한 방법을 제시한다. 기존의 고속 퓨리에 변환을 활용한 신호해석과 달리, 본 논문에서는 국소 퓨리에 변환을 사용하여 짧은 신호 구간에서의 주파수 응답을 분석한다. 본 연구에서 호흡 신호는 비접촉 방식을 활용하였으며, 초광대역 레이더 모듈을 활용하여 신호를 획득하였다. 국소 퓨리에 변환을 활용하여 호흡 상태를 검출한 후, 검출 결과에 따라 호흡 상태에 대한 분류가 가능하다. 특히 국소 퓨리에 변환은 실시간으로 호흡 상태에 대한 주파수 분석이 가능하도록 하였다. 호흡신호에 잡음이 존재할 경우를 대비하여 적절한 필터링 알고리즘이 적용되었다. 본 논문에서 제안하는 방법은 직관적으로 구현이 가능하고, 실질적으로 사람의 호흡상태에 대한 분석이 가능하도록 해준다. 제안한 방법을 검증하기 위해 호흡신호를 활용한 실험결과를 제시한다.

• 한국한의학연구원논문집
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• 제1권1호
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• pp.273-287
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• 1995

Moire topography, a simple technique for three-dimensional quantitation, was used to provide interference fringe photographs of the human back with sufficient accuracy to be used for detecting patient with asymmetry due to scoliosis, the disease of cervix and lumbar, muscle dysfunction. Contour lines are a suitable and widely accepted method of describing a three-dimensional surface. In the moire technique, contour lines of an object are produced as interference fringes while the object is illuminated by a spotlight through a special grating. The fringe pattern is produced by the interference of the grating and its shadow on the object. A photograph of a moire pattern on the human back will permit an assessment of the overall body shape and the symmetry of the back. This study uses shadow moire topography. Moire topography provides a non-invasive technique for quantifying the shape of the human body. In the use of moire topography for the Oriental Medicine Diagnosis, the strength of moire lies in the ablility to detect change due to deformity of human body.

• 한국연소학회:학술대회논문집
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• 한국연소학회 제26회 KOSCO SYMPOSIUM 논문집
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• pp.75-83
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• 2003

Diode laser absorption system is advantageous of their non-invasive nature, fast response time, high sensitivity and real-time measurement capability. Furthermore, recent advances in room-temperature, near-IR and visible diode laser sources for telecommunication, optical data storage applications are enabling combustion diagnostics system based on diode laser absorption spectroscopy. So, combined with fiber-optics and high sensitive detection strategies, compact and portable sensor system are now appearing for a variety of applications. The objective of this research is to take advantage of distributed feed-back diode laser and develope new gas sensing system. It experimentally found out that the wavelength, power characteristics as a function of injection current and temperature. In addition to direct absorption and wavelength modulation spectroscopy have been demonstrated in these experiments and have a bright prospect to this diode laser system.

• Annals of Clinical Neurophysiology
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• 제1권1호
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• pp.39-46
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• 1999

Transcranial doppler ultrasonography (TCD) is a new, non-invasive and easily applicable method to evaluate cerebral hemodynamics. Last 10 years, its use in Korea has been dramatically expanded, but the qualification of TCD laboratory has yet to be settled. Since duplex sonography is seldom used in Korea, we have to depend totally on TCD to evaluate cerebral hemodynamic changes. Thus, all of the available data from every detectabler cerebral arteries has to be obtained for accurate interpretation of TCD measurements. Moreover, flow direction and wave form should be concerned in addition to the flow velocity. In this article, I present technique to measure the anterior, meddle and posterior cerebral arteries, the internal carotid artery siphon and at cervical level, and the vertebral and the basilar artery, and normal values for these measurements which is essential for the adequate interpretation.

• Agricultural and Biosystems Engineering
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• 제1권1호
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• pp.22-29
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• 2000

The development of bio-response feedback control system known as the speaking plant approach has been a challenging task for plant production engineers and scientists. In order to achieve the aim of developing such a bio-response feedback control system, the primary concern should be to develop a practical non-invasive technique for monitoring plant growth. Those who are skilled in raising plants can sense whether their plants are under adequate water conditions or not, for example, by merely observing minor color and tone changes before the plants wilt. Consequently, using machine vision, it may be possible to recognize changes in indices that describe plant conditions based on the appearance of growing plants. The interpretation of image information of plants may be based on image features extracted from the original pictorial image. In this study, the performance of a finite element retina was optimized by a genetic algorithm. The optimized finite element retina was evaluated based on the performance of neural plant growth monitor that requires input data given by the finite element retina.

• The Korean Journal of Pain
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• 제5권1호
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• pp.85-88
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• 1992

Buerger's disease is a chronic occlusive arterial disease in which a non-arteriosclerotic lesion involves medium-sized arteries, veins, and nerves of the distal leg or arm. Sympathetic interruption is indicated to improve blood flow to the involved extremity, although sympathetic blockade can provide temporally relief of vasospasm and pain. Chemical or surgical sympathectomy has been performed for this purpose and intravenous regional sympathetic block(IRSB) is an alternative. Guanethidine or reserpine has been administered for IRSB. Intraarterial or intravenous systemic administration of prostaglandin E1(PGE1) has been recommended for the treatment of Buerger's disease. We used PGE1 for intravenous regional administration as an IRSB with results as good as that of intraarterial injection. The advantages of the method include that it is less expensive than systemic administration, less invasive than intra-arterial injection, and simple in technical application.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.322-325
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• 1997

In this study, we propose a non-invasive method to detect the drowsiness of a driver. The computer vision technology was used to extract an eye, track eyelids and measure the parameters related to the blink. We examined the blink patterns of a driver in drowsy state. For the evaluation of our image processing algorithm, the blink patterns were compared with the measured EOG signals. The result showed that our algorithm might be available in detection of drowsiness.

• 한국임상수의학회지
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• 제16권2호
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• pp.321-327
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• 1999

This study was performed to examine the clinical, serological, ultrasonographic and pathological findings in dogs with acute liver disease induced by tetrachlorethylene at 4 times of anthelminthic oral dose. The results obtained through this experiment could be summarized as follows: 1. The dogs administered with tetrachlorethylene, revealed decreased body weight, and showed lethargy and depression. 2. In serological findings, bilirubin values slightly increased, AST and ALT was decreased at 1∼3 days, and after that time increased according to the lapse of days, and revealed the highest at 5 days, and decreased to normal values at 6 days. 3. In ultrasonographic findings, branches of the portal vein were increased, the echodensity of the liver parenchyma was decreased at early stage, and increased at mid stage, and decreased at last stage. 4. In histopathological findings, necrosis of parenchymal cell, and perivascular hemorrhage were observed more severely at 6 days, as compared with 3 days. There results suggest that ultrasonographic examination is considered to be a more simple, rapid, non-invasive and useful diagnostic method for acute liver parenchymal lesion.