• Journal of Photoscience
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• 제6권3호
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• pp.91-96
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• 1999

Zeolites and microporouos materials continue to attract attention as novel hosts for photochemical reactions. Zeolities are attractive because of their ability to selectivity exchange and incorporate species within the void spaces and interconnecting channels, providing a spatial arrangement of molecules. Our research has primarily focused on intrazeolitic electron transfer from excited Ru(bpy)32+ in supercages of zeolite Y to a series of bipyridinium ions. In the Ru(bpy)32+ viologen-zeolite Y samples, the slowing of the back electron transfer from the bipyridinium radical cation to Ru(bpy)32+ allows for charge propagation via self exchange between diquat molecules. This provides an opportunity for permanent charge separation. When the migrating charge on the diquat radical within the zeolite reaches the surface, it can be transferred to a neutral viologen (PVS) in solution, resulting in permanent charge separation. The advantage of long-lived charge separation can be exploited for useful chemistry if suitable catablysts can be assembled on the zeolities. We have studied Ru(bpy)2 as water oxdiation catalysts. We have demonstrated that synthesis of RuO2 fibers on a zeolite via thermal decomposition of Ru3(CO)12 leads to the most active water decomposition catalyst reported to date. Because of the extensive interest of photochemical water reduction to H2, much is known about catalytic systems usin gone electron catalyst, and even more importantly, that no reaction of viologen occurred with H2 over this catalyst. The present challenge is to incorporate all these elements of the system into an architecture and we are examining zeolite membranes for this purpose.

• Toxicological Research
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• 제31권2호
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• pp.97-104
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• 2015

The skin exposure to solar irradiation and photoreactive xenobiotics may produce abnormal skin reaction, phototoxicity. Phototoxicity is an acute light-induced response, which occurs when photoreacive chemicals are activated by solar lights and transformed into products cytotoxic against the skin cells. Multifarious symptoms of phototoxicity are identified, skin irritation, erythema, pruritis, and edema that are similar to those of the exaggerated sunburn. Diverse organic chemicals, especially drugs, are known to induce phototoxicity, which is probably from the common possession of UV-absorbing benzene or heterocyclic rings in their molecular structures. Both UVB (290~320 nm) and UVA (320~400 nm) are responsible for the manifestation of phototoxicity. Absorption of photons and absorbed energy (hv) by photoactive chemicals results in molecular changes or generates reactive oxygen species and depending on the way how endogenous molecules are affected by phototoxicants, mechanisms of phototoxcity is categorized into two modes of action: Direct when unstable species from excited state directly react with the endogenous molecules, and indirect when endogeneous molecules react with secondary photoproducts. In order to identify phototoxic potential of a chemical, various test methods have been introduced. Focus is given to animal alternative test methods, i.e., in vitro, and in chemico assays as well as in vivo. 3T3 neutral red uptake assay, erythrocyte photohemolysis test, and phototoxicity test using human 3-dimensional (3D) epidermis model are examples of in vitro assays. In chemico methods evaluate the generation of reactive oxygen species or DNA strand break activity employing plasmid for chemicals, or drugs with phototoxic potential.

• 천문학회보
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• 제44권1호
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• pp.70.4-70.4
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• 2019

Complex organic molecules (COMs) are increasingly observed in the environs of young stellar objects (YSOs), including hot cores/corinos around high-mass/low-mass protostars and protoplanetary disks. It is widely believed that COMs are first formed in the ice mantle of dust grains and subsequently released to the gas by thermal sublimation at high temperatures (T>100 K) in strong stellar radiation fields. In this paper, we report a new mechanism that can desorb COMs from icy grain mantles at low temperatures (T<100K), which is termed rotational desorption. The rotational desorption process of COMs comprises two stages: (1) ice mantles on suprathermally rotating grains spun-up by radiative torques (RATs) are first disrupted into small fragments by centrifugal stress, and (2) COMs and water ice then evaporate rapidly from the tiny fragments (i.e., radius a <1nm) due to thermal spikes or enhanced thermal sublimation due to increased grain temperature for larger fragments (a>1 nm). We discuss the implications of rotational desorption for releasing COMs and water ice in the inner region of protostellar envelopes (hot cores and corinos), photodissociation regions, and protoplanetary disks (PPDs). In shocked regions of stellar outflows, we find that nanoparticles can be spun-up to suprathermal rotation due to supersonic drift of neutral gas, such that centrifugal force can be sufficient to directly eject some molecules from the grain surface, provided that nanoparticles are made of strong material. Finally, we find that large aggregates (a~ 1-100 micron) exposed to strong stellar radiations can be disrupted into individual icy grains via RAdiative Torque Disruption (RATD) mechanism, which is followed by rotational desorption of ice mantles and evaporation of COMs. In the RATD picture, we expect some correlation between the enhancement of COMs and the depletion of large dust grains in not very dense regions of YSOs.

• Journal of Ginseng Research
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• 제48권4호
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• pp.366-372
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• 2024

Background: The biological activity and pharmacological effects of rare ginsenosides have been proven to be superior to those of the major ginsenosides, but they are rarely found in ginseng. Methods: Ginsenoside Rb1 was chemically transformed with the involvement of methanol molecules by a synthesized heterogeneous catalyst 12-HPW@MeSi, which was obtained by the immobilization of 12-phosphotungstic acid on a mesoporous silica framework. High-performance liquid chromatography coupled with mass spectrometry was used to identify the transformation products. Results: A total of 18 transformation products were obtained and identified. Methanol was found to be involved in the formation of 8 products formed by the addition of methanol molecules to the C-24 (25), C-20 (21) or C-20 (22) double bonds of the aglycone. The transformation pathways of ginsenoside Rb1 involved deglycosylation, addition, elimination, cycloaddition, and epimerization reactions. These pathways could be elucidated in terms of the stability of the generated carbenium ion. In addition, 12-HPW@MeSi was able to maintain a 60.5% conversion rate of Rb1 after 5 cycles. Conclusion: Tandem and high-resolution mass spectrometry analysis allowed rapid and accurate identification of the transformation products through the characteristic fragment ions and neutral loss. Rare ginsenosides with methoxyl groups grafted at the C-25 and C-20 positions were obtained for the first time by chemical transformation using the composite catalyst 12-HPW@MeSi, which also enabled cyclic heterogeneous transformation and facile centrifugal separation of ginsenosides. This work provides an efficient and recyclable strategy for the preparation of rare ginsenosides with the involvement of organic molecules.

• 한국표면공학회지
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• 제34권5호
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• pp.367-377
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• 2001

Plasma is generated by electrical discharge. Most plasma generation has been carried out at low-pressure gas typically less than one millionth of atmospheric pressure. Plasmas are in general generated from impact ionization of neutral gas molecules by accelerated electrons. The energy gain of electrons accelerated in an electrical field is proportional to the mean free path. Electrons gain more energy at low-pressure gas and generate plasma easily by ionization of neutrals, because the mean free path is longer. For this reason conventional plasma generation is carried out at low pressures. However, many practical applications require plasmas at high-pressure. In order to avoid the requirement for vacuum pumps, researchers in Korea start to develop plasmas in high-pressure chambers where the pressure is 1 atmosphere or greater. Material processing, environmental protection/restoration and improved energy production efficiency using plasmas are only possible for inexpensive bulk plasmas. We thus generate plasmas by new methods and plan to set foundations for new plasma technologies for $21^{st}$ / century industries. This technological research will play a central role in material processing, environmental and energy production industries.

• Bulletin of the Korean Chemical Society
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• 제23권11호
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• pp.1604-1610
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• 2002

In the present work, we studied thiram on silver surface by SERS. Investigations of disulfides with SERS revealed that the molecules undergo a surface reaction on silver, namely easy cleavage of the S-S bond. We believe that the two S atoms of resonance formed from the thiram may be chemisorbed strongly on Ag sol. This resonance form adheres perpendicularly to the Ag surface via the two S atoms, since the ${\delta}(CH3)$ and n (CN) mode perpendicular to the surface showed strong enhancement. The important roles of halide anion adsorption have been discussed and the pH effects of thiram on Ag sol in acidic, neutral, and alkaline conditions were examined.

• 대한방사선기술학회지:방사선기술과학
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• 제30권2호
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• pp.161-165
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• 2007

알부민 수용액(pH 7)에 대한 초음파 흡수 메카니즘을 규명하기 위해 주파수 $0.2{\sim}1,000\;MHz$에 걸쳐 흡수특성측정을 하였다. 관측된 단백질 알부민 수용액의 흡수스펙트럼은 David-Cole함수의 거울상으로 가정한 완화시간의 분포함수와 일치하였다. 이 분포함수는 BSA분자의 수화평형에 의한 것이고 수화평형에 의해 넓은 주파수영역에 걸쳐 완화현상이 일어난다.

• Journal of Electrical Engineering and Technology
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• 제11권2호
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• pp.455-462
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• 2016

The electron transport coefficients in not only pure atoms and molecules but also in the binary gas mixtures are necessary, especially on understanding quantitatively plasma phenomena and ionized gases. Electron transport coefficients (electron drift velocity, density-normalized longitudinal diffusion coefficient, and density-normalized effective ionization coefficient) in binary mixtures of TEOS gas with buffer gases such as Kr, Xe, He, and Ne gases, therefore, was analyzed and calculated by a two-term approximation of the Boltzmann equation in the E/N range (ratio of the electric field E to the neutral number density N) of 0.1 - 1000 Td (1 Td = 10⁻¹⁷ V.cm²). These binary gas mixtures can be considered to use as the silicon sources in many industrial applications depending on mixture ratio and particular application of gas, especially on plasma assisted thin-film deposition.

• Transactions on Electrical and Electronic Materials
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• 제5권3호
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• pp.98-103
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• 2004

The plasma properties in the facing target sputtering system during carbon nitride film deposition have been investigated. The ionized nitrogen species of the deposited films increased with increasing discharge current and were independent of the nitrogen pressure. The nitrogen content in the films did not vary significantly with the variation of nitrogen gas. The electron temperature was high close to that in the inter-cathode region, reduced as the electrons moved away from the most intense region of magnetic confinement and increased again outside this region. Calculations based on the film composition showed that the ion to carbon atom ratio at the substrate was about 50 and that the ratio between the ionized and neutral nitrogen molecules was about 0.25.

• Bulletin of the Korean Chemical Society
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• 제34권3호
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• pp.743-748
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• 2013

The temperature dependence of the partition coefficients of a neuropeptide, substance P (SP), in isotropic acidic bicelles was investigated by using a pulsed field gradient nuclear magnetic resonance diffusion technique. The addition of negatively charged dimyristoylphosphatidylserine to the neutral bicelle changed the SP partitioning a little, which implies that the hydrophobic interaction between the hydrophobic residues of SP and the acyl chains of lipid molecules is the major interaction while the electrostatic interaction is minor in SP binding in a lipid membrane. From the temperature dependence of the partition coefficients, thermodynamic functions were calculated. The partitioning of SP into the acidic bicelles is enthalpy-driven, as it is for small unilamellar vesicles and dodecylphosphocholine micelles, while peptide partitioning into a large unilamellar vesicle is entropy-driven. This may mean that the size of lipid membranes is a more important factor for peptide binding than the surface curvature and surface charge density.