• Korean Journal of Veterinary Service
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• v.35 no.1
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• pp.59-62
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• 2012

A 3-year-old Jeju native black sow with sudden death was requested to the Jeju Self-Governing Provincial Veterinary Research Institute for diagnosis in July 2009. Because the pig died suddenly, we could not find any clinical signs. Gross lesions such as pulmonary edema, redness of heart, liver, kidney and lymph nodes were observed at necropsy. Histopathologically, there were severe eosinophilic meningoencephalitis, atrophy, degeneration and necrosis of laminar neurons, and neovascularization in cerebral cortex. Based on histopathological findings and history taking about temporal suspension of water supply, this case was diagnosed as salt poisoning of a Jeju native sow. In our best knowledge, this is the first report for salt poisoning of sow in Korea, especially in Jeju native pig.

• Korean Journal of Veterinary Service
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• v.32 no.2
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• pp.165-169
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• 2009

Suppuratives bronchopneumonia was found in a 3-month old domestic muskrat (Ondatra zibethicus). Dead muskrat showed hemorrhagic nasal discharge, severe hemorrhage and consolidation were observed in the lungs in necropsy. Histologically, severe polymorphic neutrophils and alveolar macrophages were infiltrated in the bronchus, bronchioles, alveoli. P. multocida and B. bronchiseptica were identified from the lungs, Klebsiella was isolated from the cecum. We demonstrated those organisms by biochemical test and confirmed P. multocida capsular type A by means of polymerase chain reaction (PCR).

• Korean Journal of Veterinary Research
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• v.22 no.2
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• pp.247-251
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• 1982

A 6-year-old male German Shepherd was admitted to the Armed Forces Second Animal Clinic for clinical examination The symptoms were anorexia, dyspnea, emaciation and ascites. Treatment was given for a month but its condition did not improve, euthanasia was therefore performed and the dog was submitted for necropsy. A tumor was found at the base of the heart between the ascending aorta and the pulmonary artery It was diagnosed an aortic body tumor by clinical signs, gross lesions and histopathologic features.

• Korean Journal of Veterinary Research
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• v.23 no.2
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• pp.179-182
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• 1983

This study was conducted to observe the local irritation histopathologically following the intramuscular injection of iron preparations in guinea pigs. Necropsy findings were edema, hemorrhage and darkish brown pigmentation around the injection sites. On the microscopic examination, the muscle fibers near the injection sites became pale staining or uniformly eosinophilic, indicating necrosis of the fibers, which were occasionally filled with granular bluish-staining material. The nuclei were swollen or pyknotic. Infiltrations of heterophils and macrophages containing iron were evident around the necrotized tissues and the injected iron compounds. Fibrosis was often seen between the affected muscle fibers, and this change was considered as secondary inflammatory process.

• Korean Journal of Veterinary Research
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• v.39 no.2
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• pp.353-358
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• 1999

New emerging post weaning multisystemic wasting syndrome (PMWS) threatening swine industry worldwide and investigation of the etiological agent is underway. The porcine circovirus (PCV) consistently identified from PMWS pigs and research result indicate that there is strong relationship between PCV and PMWS. Fauns with PMWS submitted pigs suffered from various PMWS typical signs and necropsy finding showed lymph node anomalies. The PCV DNA was amplified from inguinal lymph node collected from pigs with PMWS. PCV specific primers were successfully amplified PCV DNAs and were able to differentiate PCV type I and II. We have identified noble PCV virus with genetic variation. The virus showed insertion of the nucleic acid at the 5' of the genome but did not have PCR product with primer set corresponding to PCV type II virus.

• Korean Journal of Veterinary Research
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• v.53 no.1
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• pp.61-64
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• 2013

A ten-year-old dog was presented with pancreatitis and increased hepatic enzymes. On necropsy a large firm mass was observed in the liver extending to the gall bladder. Smaller masses with similar texture were found in multiple organs including lung, stomach, pancreas, lymph nodes, omentum, and mesentery. Neoplastic cells were spindle shaped with prominent osteoid production and occasional trabeculae of woven bone. Tumor cell emboli were observed in the blood vessels and lymphatics of the omentum and stomach. Hepatic osteosarcoma with systemic metastasis is very rare and may serve to broaden the diagnostic spectrum of hepatic and pancreatic diseases in dogs.

• Journal of Veterinary Clinics
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• v.20 no.3
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• pp.427-430
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• 2003

Akabane virus is a cause of severe congenital defects, but adult animals show no signs of infection. In this study, congenital abnormalitis associated with Akabane virus infection in Korean native goat. The prevalence of serum neutralizing antibodies to Akabane virus in goat population was investigated, indicating that approximately 30% of goats in Korea were seropositive(36/120). The mother goats have the highest titers of neutralizing antibodies, as 1:128. And also there showed seropositive of Akabane virus in newborn fetus fluids. The necropsy results of newborn fetus visceral organs were appeared normal. These findings provide that Akabane virus is the ethiological agent of congenital abnormalitis and stillbirth. Our results suggest that goat in natural situations are part of the Akabane virus transmission cycle.

• Journal of Veterinary Clinics
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• v.21 no.4
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• pp.413-415
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• 2004

A male Blue-fronted amazon parrot suddenly died after having a history of depression, anorexia and emaciation. At necropsy, numerous well-demarcated yellow to white firm nodules were scattered throughout the left caudal lung lobes and adjacent air sac. Histologically, the wall of air sac was significantly thickened due to necrosis and infiltration of large numbers of fungi and degenerated heterophils. Multifocal necrotizing granulomatous lesions with numerous fungal hypae as well as vasculitis and thrombosis were found in tl1e lung. The fungi had conidiophore, vesicle, phialides and conidia which were characteristic of Aspergillus sp. This is tl1e first report of mycotic air sacculitis and pneumonitis caused by Aspergillus in a parrot in Korea.

• Journal of Korean Medicine for Obesity Research
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• v.11 no.2
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• pp.25-32
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• 2011

Objectives: The purpose of this study was to investigate the acute toxicity with oral administration in ICR mice of Ohyaksungi-san fermented with Lactobacillus sp. Methods: In single oral administered toxic test, four groups were administrated different dosages(0, 1250, 2500, 5000 mg/kg) of fermented Ohyaksungi-san. After single oral administration, we observed number of death, clinical signs, body weight changes, hematological values and autopsy. Results: Compared with the control group, we could not find any toxic signs in the mortalities, clinical signs, body weight changes, necropsy findings and hematological values in all treated groups (1250, 2500 and 5000 mg/kg). Conclusions: These results indicate that the $LD_{50}$ value of fermented Ohyaksungi-san extract might be over 5000 mg/kg and it have no side toxic effect to ICR mice

• Journal of Veterinary Clinics
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• v.19 no.4
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• pp.443-446
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• 2002

A primary metastatic malignant plasma cell tumor was presented in a 7-year-old, female, mixed breed dog. The dog was admitted to Veterinary Teaching Hospital at College of Veterinary Medicine, Seoul National University after suffering from depression, anorexia, and dyspnea. The dog was euthanized due to poor prognosis. At necropsy, numerous, firm and tan round nodules, 1 to 2 cm in diameter were noted in the ribs. The nodules formed chain or were occasionally coalescing, causing osteolysis of the ribs. A large amount of clear fluid was present in the thoracic cavity. The spleen and liver were markedly enlarged and congested. Histologically, the nodular masses were diagnosed as plasma cell tumor which was believed to be originated from the rib. Evidence of metastasis was observed in the spleen, liver, and kidney.