• Natural Product Sciences
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• 제10권6호
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• pp.310-314
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• 2004

This is the re-arrangement of the 2004 Asia Nutrition & Dietary Supplement Conference organized by ABF(The Asia Business Forum) in Singapore, especially regulatory view of point of health functional foods for Korea, Japan, and China. Foods that may have health benefits beyond the traditional nutrients that they contain are often called 'Functional Foods'. The concept of functional foods has become popular in recent years, first in Japan and later in other countries, including the USA. In USA, The functional foods was controlled by ACSH (the American Council on Science and Health). In Korea, 'Functional Foods'. was defined on the 'The Law for the Health Functional Foods'(Law No. 6727 : effective as of $26^{th}$, Aug. 2002). KFDA(Korea Food and Drug Administration) is the only authority body for approval, advertisement and claims for the Health Functional Foods in Korea. In Japan, the Japan Health Food and Nutrition Food Association controls the approval, regulate functional foods' advertisement and claims under the name of FOSHU (Foods for Specified Health Uses). In China, the State Food and Drug Administration(SFDA) is the only authoritative organization for the application, supervision and administration of health related products. Asia, especially Korea, Japan and China, is one of the leader in the vitamins and dietary supplement(VDS) market. Regulatory issues on restrictions are the most important how to tap into the health functional foods market including Korea.

• Natural Product Sciences
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• 제17권3호
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• pp.206-211
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• 2011

High-performance liquid chromatography coupled to an online $ABTS^+$-based assay (online HPLC-$ABTS^+$) system was used to determine the principal antioxidants in Cudrania tricuspidata fruits. Six prenylated isoflavonoids (1 - 6) were isolated from C. tricuspidata fruits according to the online HPLC-$ABTS^+$ system. The structures of isolated compounds, alpiniumisoflavone (1), 6,8-diprenylorobol (2), 6,8-diprenylgenistein (3), pomiferin (4), 4'-methylalpiniumisoflavone (5), and osajin (6) were identified by their retention time, UV spectra, ESI-MS, and NMR data. Among these compounds, 6,8-diprenylorobol (2) and pomiferin (4) reduced A2E photooxidation in a dose dependent manner.

• 한국자기공명학회논문지
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• 제24권1호
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• pp.23-29
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• 2020

Mozart's music has been suggested to affect spatio-temporal reasoning of listeners, which has been called "Mozart effect". However, the effects of Mazart's music on human metabolism have not been known. We dissected Mozart's music into its compositional elements and studied their effects on metabolism of experimental animals. Mozart music significantly reduced cortisol level induced by stress. NMR metabolomic study revealed different urine metabolic profile according to the listening to Mozart's music. In addition, each element of music exhibited different metabolic profile. Functional MRI study also showed enhanced brain activity upon listening to Mozart's music. Taken together, Mozart's music seems to be related with brain activity, stress hormone and whole body metabolism.

• 한국식품영양학회지
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• 제34권5호
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• pp.545-552
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• 2021

HAE-06 extract is a mixture of four medicinal plants, namely Lonicerae Folium et Caulis (Lonicera japonica), Scutellariae Radix (Scutellaria baicalensis), Adenophorae Radix (Adenophora triphylla var. japonica), and Polygonati Oddorati Rhizoma (Polygonatum odoratum var. pluriflorum). The HAE-06 extract demonstrated a concentration-dependent relaxing effect and enhanced cAMP production in bronchial smooth muscle that had been stimulated to contract with acetylcholine. Using a blocker, it was confirmed that the effect was through the β2-adrenergic receptor/cAMP/PKA pathway. In addition, it is thought that the HAE-06 extract has a bronchial smooth muscle relaxation effect by reducing the inflow of Ca²⁺ through the K⁺ and Ca²⁺ channels present in the sarcoplasmic membrane. If research continues in the future, it is believed that it will be possible to use it as a material for pharmaceuticals and functional foods.

• 한국의류학회지
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• 제33권8호
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• pp.1280-1292
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• 2009

In the current fashion design, the 'environmental friendliness' affects the practically and conceptuality in all industry and culture sectors. This study seeks to examine specific design elements as the content of design factors in environment oriented fashion. The subjects of this paper are studied through scholarly journals that are confined to those from 1990 (when naturalism and ecology trends started to be in fashion) to February 2009. This study used 'Naturalism', 'Green', 'Environment-friendly', 'Eco', 'Sustainable', 'Well-being' and 'Lohas' as key words for the literature search. The analysis is performed through a content analysis and the unit of analysis is based upon the adjectives, nouns, and phrases related to the content of the design elements such as line, color, and textiles. In the results, more expression is natural, minimal, transformable, and sportive style in line, YR, white, soft, pale, and dull tone in color. The prominent textiles and texture were natural fabrics, environment-friendly fabrics, recycled fabrics, natural dyeing, functional finishes, rustic surfaces, flexibility, and extensibility. The results of this paper will help in future fashion design product development for environment-friendly fashion brands.

• 한국의류산업학회지
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• 제21권6호
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• pp.708-716
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• 2019

This study explored Jeju natural resources with healing function and tried mixed dyeing of Ecklonia cava and onion shell to improve dyeing. The results showed that silk dyed with a mixture of Ecklonia cava powder and onion shells rather than Jeju's individually dyed silk had better color power to develop fashion products. In addition, all friction lightning bolts, dry cleaning and sweat mining levels were excellent as well as excellent UV protection rates. The three baenaet jeogori worn during a birth anniversary and four rest suits that infants and children can wear comfortably maintained the dyeing and functioning of Ecklonia cava and onion shell mixture that was proven through abnormal experiments. For the three baenaet jeogori and two rest suits, the company has developed a fashion product recognized for high value-added merchandise using a variegation dyeing method made in a handmade style for expressing a person's natural sensibility through dyeing fabrics. Based on the results of the above research, it is expected that various fashion product developments will be possible by dyeing a mixture of functional and colorful extracts of the drug and colorful dye.

• Natural Product Sciences
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• 제25권2호
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• pp.165-171
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• 2019

Although the functions of a standardized extract of Gingko biloba leaves (EGb $761^{(R)}$) has been reported with regard to neurobiological properties, no attention has been paid to the impact of EGb $761^{(R)}$ on the neuronal regulation of energy homeostasis. To evaluate the hypothesis that EGb $761^{(R)}$ affect the secretion of peptide tyrosine tyrosine (PYY) and the activation of free fatty acid receptor 4 (FFA4), which are involved in the neuronal circuitries that control energy homeostasis by inducing the transfer of information about the influx of energy to the brain, we examined whether EGb $761^{(R)}$ can stimulate PYY secretion in the enteroendocrine NCI-H716 cells and if EGb $761^{(R)}$ can activate FFA4 in FFA4-expressing cells. In NCI-H716 cells, EGb $761^{(R)}$ stimulated PYY secretion and the EGb $761^{(R)}$-induced PYY secretion was involved in the increase in intracellular $Ca^{2+}$ concentration and the activation of FFA4. Furthermore, in FFA4-expressing cells, EGb $761^{(R)}$ activated FFA4. These results suggest that EGb $761^{(R)}$ may affect the control of energy homeostasis via the regulation of PYY secretion and FFA4 activation.

• Natural Product Sciences
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• 제25권4호
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• pp.293-297
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• 2019

Policosanol extracted from sugarcane wax is a generic term used for total fatty alcohols obtained from esterification of fatty acids. It has been approved as a health functional food by the Ministry of Food and Drug Safety of Korea in 2006. Policosanol is well-known to aid in lowering blood cholesterol level. Recently, several studies have reported the physiological activities of policosanol, such as anti-inflammatory effects, antioxidant effects, and lowering of the incidence of ageing-related diseases, for example, hypertension, stroke, among others. This review describes the physiological activities of policosanol and its applications in the field of health functional foods.

• Journal of Dairy Science and Biotechnology
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• 제16권2호
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• pp.106-118
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• 1998

유청은 치즈제조시 부산물로 얻어지는 천연물이며, 새로운 기술발전에 따라 유청단백질의 농축물과 유청분획물들이 여러모로 이용 가능하게 되었고, 또한 여러 종류의 식품의 원료로 제공하게 되었다. 농축 유청단백질은 겔화, 유화성, 휩핑, 수분결합성, 지방대체성 등의 다양한 기능성을 함유하고 있다. 유청의 새로운 분획물인 알파락트알부민, 락토페린, 락토페록시다아제, 펩타이드 등은 이들의 생활성이나 건강향상성때문에 전세계적으로 관심이 높다. 이들 분획물에서 천연 항생물질, 천연 보존료 및 면역 향상 물질 등으로 새롭게 사용이 가능한 것으로 발견되었다. 기능성 식품산업의 성장에 힘입어 증가 추세에 있는 많은 제조업자들이 새로운 제품개발을 성공적으로 하는데 유청의 영양적, 기능적 조건들이 유리하다. 미국은 유청생산이 전세계에서 가장 큰 유일한 생산국이고 또한 수출국이다. 1997년에는 백만톤 이상의 유청제품들이 미국에서 제조되었다.

• 대한화장품학회지
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• 제37권4호
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• pp.289-295
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• 2011

최근 전 세계적으로 석유 유래 합성 화장품 원료의 사용을 배제한 천연 화장품을 찾는 고객들이 계속적으로 증가하고 있지만 이러한 천연 화장품 중에서도 기능성을 소구하는 제품은 거의 없는 상황이다. 이는 천연 유래 원료중에서 기능성이 검증된 원료가 거의 없을 뿐 아니라, 그러한 천연 기능성 원료들이 있다고 하더라도 그것들을 천연 원료만으로 안정한 제형을 유지하기가 매우 힘들기 때문이다. 본 연구는 난용성 천연 주름 기능성 물질인 올레아놀릭산을 천연 유래 수첨 레시틴을 이용하여 안정하게 가용화시키는 것에 관한 것이며, 유기농 화장품 인증이 가능한 가용화 제형의 처방을 개발하는 것을 목표로 하였다. 다른 합성 가용화제를 사용할 경우 $45^{\circ}C$에서 2 ~ 3일 내에 올레아놀릭산의 석출이 관찰되었지만, 천연 유래 수첨 레시틴을 이용한 제형에서는 4주 동안 입자 크기의 큰 변화 없이 안정하게 유지되었다. 제형 내 올레아놀릭산의 함량은 $25^{\circ}C$ 및 $40^{\circ}C$에서 보관중인 샘플을 대상으로 24주간 측정하였는데, 두 온도에서 모두 90 % 이상을 보여주어 올레아놀릭산이 제형 내 분해 없이 안정하게 유지되는 것을 확인하였다. 또한 보습력 및 주름 개선 등의 임상시험을 통해 제품의 피부 효능과 안전성을 확인하였다.