• Korean Institute of Interior Design Journal
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• v.23 no.2
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• pp.3-11
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• 2014

Light has been considered as one of the most important elements in architectural design. Light provides occupants in buildings a lot of architectural experiences by interrelating the space, shape and other design elements. Especially, natural light is the valuable source to create the better indoor space compared to artificial light. It is a sustainable energy source and offers a more natural environment. It also enables occupants to perceive the form and depth of space. In general. many of architects including Henri Ciriani have tried to design buildings with natural light expecting optimum indoor environment. Therefore, this paper tried to examine the works of Henri Ciriani and analyze how to control the light in his works. For this purpose, two museums designed by Henri Ciriani-Arles Museum of Archaeology and Great War Historical Museum in Peronne - were selected to analyze how Henri Ciriani used light in his design phase and applied it to his museum works. According to the results of the study, it has been proved that Henri Ciriani tried to realize a space continuum through the spatial expansion, openness and closeness by natural light and incorporate the architectural form, interior space and exhibition circulation with natural light in order to create innovative exhibition space in museum buildings.

• Journal of Korean Society of Forest Science
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• v.97 no.2
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• pp.156-164
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• 2008

Recognizing the importance of the multi-purpose management of natural deciduous forest, this study was carried out to implement the partial cutting for stand regulation to examine agroforestry practice as well as other concurrent forest resource production, and to investigate the changes in stand characteristics and understory vegetation in a silvopasture practiced natural deciduous stand in the Research Forest of Kangwon National University, Korea. Three different partial cutting intensities (68.1%, 48.6%, and control) were performed in the unmanaged natural deciduous stand in order to improve the growing condition, especially light condition, for introducing some commercial herbaceous plants on the forest floor to establish agroforestry and/or silvopastoral system. Dominated by Quercus varibilis Blume (50.5%) and Quercus dentata Thum. ex Murray (42.6%), eight tree species were composed of the study forest, including poles of Pinus desiflora Siebold & Zucc and sapling of Pinus Koraiensis Siebold & Zucc. The total of 87 (13 tree species, 12 shrub species, 58 herbaceous species, and 4 woody climbers) vascular plant species were observed in study site after partial cutting treatments, while that of before partial cutting was 53 species (14 tree species, 8 shrubs species, 30 herbaceous species, and 1 woody climbers). The proportion of life form spectra in plot B was Mi (28.4%)-Na (23.0%)-Ge (17.5%)-Ch (10.8%)-He (9.5%)-MM (6.7%)-Th (4.1%). No statistically significant differences were observed in changes of life form spectra from before to after partial cutting treatment and among partial cutting gradients in this study. Partial cutting and scratching for forage sowing made plants invade easily on the forest floor, and light partial cutting (LPC) plot (500 stems/ha) had much higher number of undersory species than those of heavy partial cutting (HPC) plot (310 stems/ha) and control plot (1,270 stems/ha).

• Animal cells and systems
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• v.12 no.4
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• pp.193-201
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• 2008

The eventual goal of tumor immunotherapy is to develop a vaccine inducing a specific anti-tumor immunity. Cytokine gene therapy is an effective way at least in animal models, but limited efficacy and various side effects obstruct clinical applications. In this study, we developed a tumor vaccine expressing a membrane-bound form of IL-2(mbIL-2) and SDF-1 in B16F10 melanoma cells. The tumor clones expressing mbIL-2 showed reduced tumorigenicity, and additional expression of SDF-1 to mbIL-2 expressing tumor cells caused more severe reduction in tumorigenicity. However, expression of the SDF-1 alone did not affect on the tumorigenicity, probably because of limited production of SDF-1 in the SDF-1 transfected clones. When the mice once rejected mbIL-2/SDF-1 expressing tumor clone were re-challenged with wild type B16F10 tumor cells, all of the mice survived. This result suggests that mbIL-2/SDF-1 tumor clone is effective in inducing systemic anti-tumor immunity against wild type B16 melanoma. Furthermore, culture supernatant of tumor clones expressing SDF-1 induced lymphocyte migration in vitro. These results, all together, suggest that expression of mbIL-2 and SDF-1 in tumor cells enhances anti-tumor immune responses through different roles; the secreted SDF-1 may function as a chemoattractant to recruit immune cells to tumor vaccine injection site, and the mbIL-2 on tumor cells may provide costimulatory signal for CTL activation in physical contacts.

• Annual Conference on Human and Language Technology
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• 1997.10a
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• pp.463-468
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• 1997

자연언어 대화는 사람들이 사용하는 가장 자연스러운 의사소통 수단이다. 따라서, 자연언어 대화 인터페이스를 통해서 사용자와 시스템이 편리하고 자연스러운 방법으로 의사를 교환할 수 있다. 본 논문에서는 대화 인터페이스의 필요성과 폼에 기반한 대화 인터페이스 기법에 대해서 설명한다, 폼 기반 인터페이스란 데이터베이스 검색을 위해서 질의어를 생성할 때 검색에 대한 제한 조건을 폼(form)의 형태로 나타내어, 사용자와의 대화를 통해서 폼 정보를 추출하고, 이렇게 완성된 폼을 이용하여 질의어를 생성하는 것을 말한다. 본 논문에서는 이러한 폼 기반 대화 인터페이스에서 시스템이 대화를 적절히 유도하고 사용자의 응답이나 질문에 대해 적절히 대응하기 위한 폼과 재귀적 대화 전이망(recursive dialogue transition networks)을 이용한 대화 모델에 대해 제안한다.

• Archives of Pharmacal Research
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• v.10 no.4
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• pp.258-259
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• 1987

An alkaloid was isolated form water-soluble fraction of Panax ginseng roots. It was characterized by spectroscopic data and dynthesis as 4, 5, 6, 7-tetrahydroimidazo (4, 5-c) pyridine-6-carboxylic acid or spinacine, which was first isolated from the plant kingdom.

• Proceedings of the Korean Society of Life Science Conference
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• 2001.09a
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• pp.45-45
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• 2001

• Journal of Mechanical Science and Technology
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• v.18 no.4
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• pp.699-708
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• 2004

Natural gas hydrate typically contains 85 wt.% water and 15 wt.% natural gas, and commonly belongs to cubic structure I and II. When referred to standard conditions, 1 ㎤ solid hydrate contains up to 200㎥ of natural gas depending on pressure and temperature. Such the large volume of natural gas hydrate can be utilized to store and transport a large quantity of natural gas in a stable condition. In the present investigation, experiments were carried out for the formation of natural gas hydrate governed by pressure, temperature, gas compositions, etc. The results show that the equilibrium pressure of structure II is approximately 65% lower and the solubility is approximately 3 times higher than structure I. It is also found that for the sub-cooling of structure I and II of more than 9 and 11 K respectively, the hydrates are rapidly being formed. It is noted that utilizing nozzles for spraying water in the form of droplets into the natural gas dramatically reduces the hydrate formation time and increases its solubility at the same time.

• Structural Engineering and Mechanics
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• v.28 no.5
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• pp.515-524
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• 2008

In this paper the effect of prestressing force on the first flexural natural frequency of beams is studied. Finite element technique is used to model the beam-tendon system, and the prestressing force is applied in the form of initial tension in the tendon. It is shown that the effect of prestressing force on the first natural frequency depends on bonded and unbonded nature of the tendon, and also on the eccentricity of tendon. For the beams with bonded tendon, the prestressing force does not have any appreciable effect on the first flexural natural frequency. However, for the beams with unbonded tendon, the first natural frequency significantly changes with the prestressing force and eccentricity of the tendon. If the eccentricity of tendon is small, then the first natural frequency decreases with the prestressing force and if the eccentricity is large, then the first flexural natural frequency increases with the prestressing force. Results of the present study clearly indicate that the first natural frequency can not be used as an easy indicator for detecting the loss of prestressing force, as has been attempted in some of the past studies.

• The Research Journal of the Costume Culture
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• v.11 no.3
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• pp.404-415
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• 2003

The main purpose of this exploratory research was to examine the characteristics of consumers who patronize natural-dyed clothes and their perceptions regarding natural-dyed clothes. Thirty three participants who have worn natural-dyed clothes were interviewed for the study. They were asked about the styles and price of natural-dyed clothes they owned, their evaluation on them, and the lifestyles of themselves. Existence of subculture among the interviewes and its characteristics were also probed. The results indicated that natural-dyed clothes are relatively high-priced, mostly of modified hanbok style, and became popular in recent years. Interviewees frequently mentioned uniqueness and comfort as the main benefits of natural-dyed clothes, and expressed dissatisfaction regarding color fastness, easy care and problem of coordination. The consumers of natural-dyed clothes appeared to have strong preferences for environment conservation and Korean traditional culture. They also seemed to form a subcultural group who have commonality in their involvement in Korean cultural activities, mainly tea ceremony.

• IMMUNE NETWORK
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• v.9 no.5
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• pp.158-168
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• 2009

Tumor therapy using cytokines has been developed for last two decades. Several recombinant cytokines and tumor cell vaccines produced by cytokine gene transfer have been in clinical trials, but several side effects hamper routine clinical applications. Many cytokines are originally expressed as membrane-bound form and then processed to secretory form exerting paracrine effects. Though functional differences of these two types of cytokines are elusive yet, the membrane-bound form of cytokine may exert its effects on restricted target cells as a juxtacrine, which are in physical contacts. With the efforts to improve antitumor activities of cytokines in cancer patients, developing new strategies to alleviate life-threatening side effects became an inevitable goal of tumor immunologists. Among these, tumor cell vaccines expressing cytokines as membrane-bound form on tumor cell surface have been developed by genetic engineering techniques with the hope of selective stimulation of the target cells that are in cell-to-cell contacts. In this review, recent progress of tumor cell vaccines expressing membrane-bound form of cytokines will be discussed.