• Journal of Ginseng Research
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• v.23 no.1 s.53
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• pp.38-43
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• 1999

Ginseng total saponins (ginsenosides) are biologically active main ingredients of Panax ginseng. In present study, we have investigated whether pretreatment of ginsenosides inhibited capsaicin-induced pain at the spinal level, in the view that capsaicin causes substance P (SP) release from primary afferents. Ginsenosides relieved capsaicin-induced pain in a dose-dependent manner. The $ED_{50}$ of the effect was 43 (20-93, $95\%$ C.I.) ${\mu}g/mouse$. We investigated excitatory amino acids-induced nociceptive responses in mice, because these agents are also involved in nociceptive transmission in the spinal cord. Coadministration of ginsenosides with N-methyl-D-aspartate (NMDA) or kainate via i.t. inhibited NMDA- but not kainate-induced pain behaviors. The $ED_{50}$ for the inhibition of NMDA-induced pain by ginsenosides was 37 (21-66, $95\%$ C.I.) ${\mu}g/mouse$. These results suggest that the ginsenosides-induced antinociception results from blocking of pain transmitter-induced nociceptive information at the spinal level.

• Journal of Korean Academy of Nursing
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• v.29 no.5
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• pp.1021-1029
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• 1999

Koreans rarely complain of depression or other psychological problems because mental illness is viewed as a stigmatizing and threatening experience. This study examined the relationships among stressful life events, close relationships, self-esteem. and depression in 400 college women aged 18 to 30 years. Depression was positively related to stressful life events (r＝.21, p＝＜.01). Depression and stressful life events were negatively associated with self-esteem (r＝-.67; r＝-.11, p＜.01; p＜.05 respectively). Close relationships with women and men friends were each negatively associated with depression (r＝-.24; r＝-.16, p＜.01; p＜.05). Close relationships with women and men friends were positively associated with self-esteem (r＝.23; r＝.20, p＜.01). Forty nine percent of variance in depression rates in this sample was explained. After adjustment for degrees of freedom, a total of 49% of the variance in depression was explained by self-esteem and stressful life events. This investigation into the relationships among the variables influencing depression for college women is a critical issue as health professionals need to be aware that college women are at considerable risk for depression. Effective psychosocial interventions are those designed for specific populations to meet unique care needs and since young Korean women may be at considerable risk for depression.

• The Korean Journal of Nuclear Medicine
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• v.25 no.2
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• pp.207-210
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• 1991

The purpose of this study was to examine the existence of a lag phase of gastric emptying of solid meals. We studied solid phase gastric emptying in 26 normal subject using continuous data aquisition for 30 minutes. Each ingested a 300 g meal containing $^{99m}Tc-labeled$ scrambled egg (solid 150g, milk 150 ml). Lag phase was determined by 1) inspection of the gastric emptying curve 2) time to a 2% decrease in stomach activity 3) the time of visual appearance of duodenal activity on computer image We concluded that solid meal lag phase exist.

• BMB Reports
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• v.37 no.3
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• pp.362-369
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• 2004

The human folate receptor (hFR) is a glycosylphosphatidylinositol (GPI) linked plasma membrane protein that mediates delivery of folates into cells. We studied the sorting of the hFR using transfection of the hFR cDNA into MDCK cells. MDCK cells are polarized epithelial cells that preferentially sort GPI-linked proteins to their apical membrane. Unlike other GPI-tailed proteins, we found that in MDCK cells, hFR is functional on both the apical and basolateral surfaces. We verified that the same hFR cDNA that transfected into CHO cells produces the hFR protein that is GPI-linked. We also measured the hFR expression on the plasma membrane of type III paroxysmal nocturnal hemoglobinuria (PNH) human erythrocytes. PNH is a disease that is characterized by the inability of cells to express membrane proteins requiring a GPI anchor. Despite this defect, and different from other GPI-tailed proteins, we found similar levels of hFR in normal and type III PNH human erythrocytes. The results suggest the hypothesis that there may be multiple mechanisms for targeting hFR to the plasma membrane.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.11
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• pp.49-58
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• 2010

In this paper, we present a methodology for fast segment restoration under multiple simultaneous link failures in mesh-type MPLS networks. The salient feature of the methodology is that both resilience and QoS constraint conditions have been taken into account for fast segment restoration. For fast restoration, a sufficient condition for testing the existence of backup segments with guaranteed-resilience has been derived for a mesh-type MPLS network. The algorithms for constructing backup segments which can meet both resilience and QoS constraint conditions are then presented with illustrating examples. Finally, simulation has been done to show the efficiency of the proposed segment restoration algorithms.

• Journal of Broadcast Engineering
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• v.23 no.5
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• pp.614-621
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• 2018

This paper proposes a method of restoring corrupted depth image captured by depth camera through unsupervised learning using generative adversarial network (GAN). The proposed method generates restored face depth images using 3D morphable model convolutional neural network (3DMM CNN) with large-scale CelebFaces Attribute (CelebA) and FaceWarehouse dataset for training deep convolutional generative adversarial network (DCGAN). The generator and discriminator equip with Wasserstein distance for loss function by utilizing minimax game. Then the DCGAN restore the loss of captured facial depth images by performing another learning procedure using trained generator and new loss function.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.05a
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• pp.442-447
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• 2007

A very abnormal vibration was occurred at the LP(low pressure) turbine continuously during the pre-operation for a 550MW class USC(ultra super critical) steam turbine. This vibration was initiated at the rotating speed of about 3,450rpm and then the vibration amplitude was highly increased the number by $2{\sim}3$ times with the increase of the rotating speed to the rated speed(3,600rpm). In this paper, this abnormal vibration named spike vibration. This spike vibration was caused by the rubbing between the rotating bucket tip seal and the Lower Half of spill strip. Also, this paper presents the mechanism of the spike vibration and the proper method to eliminate this abnormal vibration problem. This result would be good practice to find the solution of similar high vibration in the USC steam turbines for power plant as well as industrial rotating machineries.

• Journal of Microbiology and Biotechnology
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• v.28 no.2
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• pp.330-337
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• 2018

Polycyclic aromatic hydrocarbons (PAHs), including naphthalene, are widely distributed in nature. Naphthalene has been regarded as a model PAH compound for investigating the mechanisms of bacterial PAH biodegradation. Pseudomonas sp. AS1 isolated from an arseniccontaminated site is capable of growing on various aromatic compounds such as naphthalene, salicylate, and catechol, but not on gentisate. The genome of strain AS1 consists of a 6,126,864 bp circular chromosome and the 81,841 bp circular plasmid pAS1. Pseudomonas sp. AS1 has multiple dioxygenases and related enzymes involved in the degradation of aromatic compounds, which might contribute to the metabolic versatility of this isolate. The pAS1 plasmid exhibits extremely high similarity in size and sequences to the well-known naphthalene-degrading plasmid pDTG1 in Pseudomonas putida strain NCIB 9816-4. Two gene clusters involved in the naphthalene degradation pathway were identified on pAS1. The expression of several nah genes on the plasmid was upregulated by more than 2-fold when naphthalene was used as a sole carbon source. Strains have been isolated at different times and places with different characteristics, but similar genes involved in the degradation of aromatic compounds have been identified on their plasmids, which suggests that the transmissibility of the plasmids might play an important role in the adaptation of the microorganisms to mineralize the compounds.

• Transactions on Electrical and Electronic Materials
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• v.1 no.1
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• pp.12-16
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• 2000

In this paper, we analyze self field effects of Bi-2223 tape-stacked cable assuming constant current density in the cross section of stacked cable. Generally, the critical current of Bi-2223 tape-stacked-cable in much less than the total summation of critical currents of each tape, which is mainly due to the self magnetic fields of the cable itself. Therefore, to predict the critical current of Bi-2223 tape-stacked-cable, we needs to analyze the self filed effects on the stacked cable as well as critical current density data(J$\_$C/) of one tape. To make it more complex, the critical current degradation of Bi-2223 tape is an-isotropic; the critical current is lower in the normal magnetic field(to the tape surface) than in the parallel field. In the paper, a novel approach to predict the critical current of a Bi-2223 tape-stacked-cable from a J$\_$C/-B curve of one tape is presented with the assumption of constant current density across the stacked cable, The approach basically includes the load analysis of the stacked tapes, and its usefulness is confirmed by the experimental data.

• Advances in Traditional Medicine
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• v.9 no.1
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• pp.14-19
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• 2009

The aim of this study is to evaluate appraiser's consistency and accuracy about pulse diagnosis (PD) in discrimination of eight-constitutions using Gage R&R study. Cumulative numbers of PD for discrimination of eight constitutions of three appraisers' experience were 75,000 cases, 50,000 cases, 1,100 cases, respectively. Three Appraisers diagnosed subject's eight-constitutions by PD with blinded method. Gage R&R study was used to verify the results. In the measurements of consistency, appraiser B (agreement = 80%, Value of k = 0.8276) was very good, appraiser A (agreement = 70%, Value of k = 0.7465) was good, and appraiser C (agreement = 50%, Value of k = 0.5365) was moderate. In the measurements of accuracy, appraiser B (agreement = 70%, Value of k = 0.6812) was good, appraiser A (agreement = 60%, Value of k = 0.6414) was good, and appraiser C (agreement = 0%, Value of k = -0.1000) was poor. The results suggest that accuracy of discrimination of constitutions relatively depend on experience and number of cases of PD. Further large controlled study is needed to evaluate the accuracy of PD.