• 제목/요약/키워드: multivalent

검색결과 92건 처리시간 0.035초

SOME APPLICATIONS AND PROPERTIES OF GENERALIZED FRACTIONAL CALCULUS OPERATORS TO A SUBCLASS OF ANALYTIC AND MULTIVALENT FUNCTIONS

  • Lee, S.K.;Khairnar, S.M.;More, Meena
    • Korean Journal of Mathematics
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    • 제17권2호
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    • pp.127-145
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    • 2009
  • In this paper we introduce a new subclass $K_{\mu}^{\lambda},{\phi},{\eta}(n;{\rho};{\alpha})$ of analytic and multivalent functions with negative coefficients using fractional calculus operators. Connections to the well known and some new subclasses are discussed. A necessary and sufficient condition for a function to be in $K_{\mu}^{\lambda},{\phi},{\eta}(n;{\rho};{\alpha})$ is obtained. Several distortion inequalities involving fractional integral and fractional derivative operators are also presented. We also give results for radius of starlikeness, convexity and close-to-convexity and inclusion property for functions in the subclass. Modified Hadamard product, application of class preserving integral operator and other interesting properties are also discussed.

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양이온교환막 표면의 전기투석 물분해에서 다가의 큰 이온성분자에 의해 형성된 고정층 바이폴라 계면의 영향 (Effects of Immobilized Bipolar Interface Formed by Multivalent and Large Molecular Ions on Electrodialytic Water Splitting at Cation-Exchange Membrane Surface)

  • Seung-Hyeon Moon;Moon-Sung Kang;Yong-Jin Choi
    • 멤브레인
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    • 제13권3호
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    • pp.143-153
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    • 2003
  • 본 연구에서는 양이온교환막 표면에 형성된 바이폴라 계면이 물분해 현상에 미치는 영향을 조사하였다. 실험결과, 전기투석 중 막표면에 형성된 고정화된 바이폴라 계면이 심각한 물분해를 유발함을 알 수 있었다. 특히, 고정화된 바이폴라 계면은 다가 양이온이 전해질로 이용되는 전기투석 시스템에서 양이온교환막 표면에 쉽게 형성됨을 알 수 있었다. 낮은 용해도적 상수를 갖는 다가 양이온들은 급격한 물분해를 유발하였는데 이는 이들이 막표면에서 쉽게 수산화물의 형태로 침적되며 따라서 수소-친화 그룹과 수산화-친화 그룹으로 구성된 바이폴라 계면이 막-용액 계면에 형성됨을 알 수 있었다. 따라서 물분해는 막 표면의 금속수산화물 층과 막의 고정전하 그룹간에 발생되는 강한 전기장에 의해 크게 활성화됨을 알수 있다. 또한 이와 유사하게 분자량이 큰 유기 상대이온들이 막표면에 누적되는 경우에도 고정화된 바이폴라 계면이 형성되어 한계전류밀도 이상에서 심각한 물분해를 유발하였다. 따라서 전기투석의 고전류 운전시 효율 향상을 위해서는 막표면에 유발되는 고정화된 바이폴라 계면의 형성을 억제하는 것이 매우 중요함을 알 수 있다.

Effect of Carbohydrates to Protein Ratio in EPS on Sludge Settling Characteristics

  • Shin, Hang-Sik;Kang, Seok-Tae;Nam, Se-Yong
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제5권6호
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    • pp.460-464
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    • 2000
  • Extracellular polymeric substances (EPS) are believed to play a role in the binding and formation of microbial flocs. However, the precise role is not well known. Sludge settling characteristics and the carbohydrate to protein ratio in EPS were tested with various airflow rates in this study. Sludge was collected from three modified sequencing batch reactors (SBRs), which were operated at 16$\^{C}$ with an airflow rate of 0.8L/min, 3L/min and 6L/min, respectively. During the operation, the reactor operated at an airflow rate of 0.8L/min showed sludge volume index (SVI) of 80 to 90ml/g and a constant ratio of carbohydrate to protein in the EPS, while a significant increase in the SVI was seen in the other reactors. Sludge bulking increased the amount of carbohydrate in the EPS, while kept protein almost constant in the airflow rate of 3L/min ad 6L/min. Surface charge also increased with increases in the carbohydrate to protein ratio in the EPS, which weakens the attraction between the EPS and multivalent cations. The ratio of carbohydrate to protein in the EPS was tween the EPS and multivalent cations. The ratio of carbohydrate to protein in the EPS was inferred to be essential for bioflocculation.

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Mechanisms of Macromolecular Interactions Mediated by Protein Intrinsic Disorder

  • Hong, Sunghyun;Choi, Sangmin;Kim, Ryeonghyeon;Koh, Junseock
    • Molecules and Cells
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    • 제43권11호
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    • pp.899-908
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    • 2020
  • Intrinsically disordered proteins or regions (IDPs or IDRs) are widespread in the eukaryotic proteome. Although lacking stable three-dimensional structures in the free forms, IDRs perform critical functions in various cellular processes. Accordingly, mutations and altered expression of IDRs are associated with many pathological conditions. Hence, it is of great importance to understand at the molecular level how IDRs interact with their binding partners. In particular, discovering the unique interaction features of IDRs originating from their dynamic nature may reveal uncharted regulatory mechanisms of specific biological processes. Here we discuss the mechanisms of the macromolecular interactions mediated by IDRs and present the relevant cellular processes including transcription, cell cycle progression, signaling, and nucleocytoplasmic transport. Of special interest is the multivalent binding nature of IDRs driving assembly of multicomponent macromolecular complexes. Integrating the previous theoretical and experimental investigations, we suggest that such IDR-driven multiprotein complexes can function as versatile allosteric switches to process diverse cellular signals. Finally, we discuss the future challenges and potential medical applications of the IDR research.

T-cell Epitope을 운반할 수 있는 재조합소아마비바이러스 벡터의 제조 및 특성연구 (Construction and Characterization of Recombinant Poliovirus that Delivers T-cell epitope)

  • 조성필;이범용;정수일;민미경
    • 대한바이러스학회지
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    • 제28권2호
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    • pp.139-146
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    • 1998
  • Recombinant polioviruses have been developed by many research groups for use as vaccine vector because poliovirus induces mucosal immunity as well as humoral immunity through oral uptake. We assessed the potential use of poliovirus as a T-cell epitope carrier. Recombinant poliovirus V129 5L was constructed to have a substituted T-helper epitope from the core protein of Hepatitis B virus at neutralization antigenic site 1 on its VP1 capsid protein. The recombinant virus replicated less efficiently than type 1 poliovirus Mahoney strain. The V129 5L formed a little smaller plaques than the Mahoney strain and showed some 1.25 log unit lower titer at the peak in the one-step growth kinetics though it had similar growth profile to that of the Mahoney strain. Since V129 5L recombinant virus was genetically stable even after 24 successive passages in HeLa cells, the antigenic site 1 on VP1 capsid protein was confirmed for its ability of carrying T cell epitope. The genetic stability of V129 5L also indicated that recombinant poliovirus can be successfully utilized for the development of the multivalent vaccines.

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