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The Current and Future State of Academic Medicine in Korea: Education, Research, and Patient Care (우리나라 의학의 현실과 미래: 교육, 연구, 진료를 중심으로)

  • Jeong, Dae Chul
    • Korean Medical Education Review
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    • v.21 no.2
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    • pp.73-79
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    • 2019
  • Academic medicine is built from a foundation of education, research, and patient care. Since good patient care results from the application of medical research and continuous education, these three components cannot be separated for medical development to occur. In Korea, many obstacles hinder the achievement of academic medicine, such as an inefficient medical delivery system, limitations of primary care, low insurance prices, and no long-term health care plan. Medical education has changed to outcome-based education, but presented temporal integration status. Governance of healthcare research is not centralized, and Korea is awarded relatively fewer grants than other countries. Medical professors have reached a burnout state due to patient care responsibilities in addition to research and education duties. Many medical systems, including the medical delivery system and insurance problems, may contribute to distrust between doctors and patients. The government is not involved in a long-term health care policy. The multitude of factors mentioned here are hindering the achievement of academic medicine in Korea.

Sirius: The KASI-SNU Optical Intensity Interferometer

  • Oh, Junghwan;Trippe, Sascha;Wagner, Jan;Byun, Do-young
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.1
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    • pp.58.3-58.3
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    • 2019
  • Optical intensity interferometry, developed in the 1950s, is a simple and inexpensive method for achieving angular resolutions on microarcsecond scales. Its low sensitivity has limited intensity interferometric observations to bright stars so far. Substantial improvements are possible by using avalanche photodiodes (APDs) as light detectors. We present here the results of laboratory measurements with a prototype astronomical intensity interferometer using APDs in continuous ("linear") detection mode - arguably, the first of its kind. We used two interferometer configurations, one with zero baseline and one with variable baseline. Using a superluminous diode as light source, we unambiguously detected Hanbury Brown-Twiss photon-photon correlations at very high significance. From measuring the correlation as function of baseline, we measured the angular diameter of the light source, in analogy to the measurement of the angular diameter of a star. Our results demonstrate the possibility to construct large astronomical intensity interferometers that can address a multitude of astrophysical science cases.

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The history of the fermented fisheries industry (수산 발효식품 산업 발전)

  • Song, Ho-Su;Kim, Sang Moo
    • Food Science and Industry
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    • v.55 no.3
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    • pp.284-300
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    • 2022
  • Indigenous fermented foods have played a vital role in human history, and continue to offer a multitude of diverse sensory characteristics. According to earthenware relic, the fermented fisheries products might be consumed in Korean peninsula from Paleolithic period. The traditional Korean fermented fish products are classified into four groups; Jeot-gal (sik-hae), Aek-jeot, Seasoned Jeot-gal, and Seasoned Aek-jeot. Jeot-gal is a fermented fishery with salt. Aek-jeot is a liquid part of Jeot-gal. Sik-hae is manufactured by fementing fishery with salt, cereal, malt powder, etc. Seasoned Jeot-gal is a salt-seasoned fish with red pepper powder, garlic, onion, etc. Seasoned Aek-jeot is a seasoned product by adding "salt-water" or "condiment" to Aek-jeot. The fermented fisheries industry has traditionally been succeeded mainly in a cottage scale to the middle of 20th century. Thereafter, together with the development of pelagic fishery, the fermented fisheries industry also developed constantly to an enterprise size.

Ataxia-Telangiectasia Mutated Is Involved in Autolysosome Formation

  • Mihwa Hwang;Dong Wha Jun;Bo Ram Song;Hanna Shim;Chang-Hun Lee;Sunshin Kim
    • Biomolecules & Therapeutics
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    • v.31 no.5
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    • pp.559-565
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    • 2023
  • Ataxia-telangiectasia mutated (ATM), a master kinase of the DNA damage response (DDR), phosphorylates a multitude of substrates to activate signaling pathways after DNA double-strand breaks (DSBs). ATM inhibitors have been evaluated as anticancer drugs to potentiate the cytotoxicity of DNA damage-based cancer therapy. ATM is also involved in autophagy, a conserved cellular process that maintains homeostasis by degrading unnecessary proteins and dysfunctional organelles. In this study, we report that ATM inhibitors (KU-55933 and KU-60019) provoked accumulation of autophagosomes and p62 and restrained autolysosome formation. Under autophagy-inducing conditions, the ATM inhibitors caused excessive autophagosome accumulation and cell death. This new function of ATM in autophagy was also observed in numerous cell lines. Repression of ATM expression using an siRNA inhibited autophagic flux at the autolysosome formation step and induced cell death under autophagy-inducing conditions. Taken together, our results suggest that ATM is involved in autolysosome formation and that the use of ATM inhibitors in cancer therapy may be expanded.

Clinical efficacy of activated irrigation in endodontics: a focused review

  • Amelia Wan Tin Cheung;Angeline Hui Cheng Lee;Gary Shun Pan Cheung
    • Restorative Dentistry and Endodontics
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    • v.46 no.1
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    • pp.10.1-10.16
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    • 2021
  • Root canal debridement, which includes the removal of infected tissues and microbial biofilms, is considered the corner stone of root canal treatment. Chemical adjuncts play a multitude of functions in this regard, as tissue solvents, antimicrobial agents and for removing the smear layer. These adjuncts (irrigants) are usually delivered using a syringe and needle. With increasing knowledge of the complexity of root canal anatomy and tenacity of microbial biofilms, the need for strategies that potentiate the action of these irrigants within the root canal system cannot be overemphasized. Several such activated irrigation strategies exist. The aim of this review is to comprehensively discuss the different irrigant activation methods from the context of clinical studies.

Hyper-reality Metaverse Technology Trends and Development Prospects (초실감메타버스 기술 동향 및 발전 전망)

  • Y.S. Cho;E.H. Hyun;S.J. Bae;H. Jeong;S.D. Ahn
    • Electronics and Telecommunications Trends
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    • v.39 no.2
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    • pp.1-11
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    • 2024
  • The metaverse is expected to evolve into an immersive environment based on photorealistic stereoscopic imaging to integrate real and virtual worlds. To transition from flat images to immersive stereoscopic images, such as light fields and holograms, a continuous cycle of technological development should be reached in media, content, and device technologies, ranging from acquisition and generation to transmission and synthesis as well as reproduction and interaction. Additionally, owing to the multitude of components involved in the metaverse, proper service realization will be challenging without concurrent advancements in computing and communication technologies that facilitate the integration of such components. We introduce research and development trends in media, contents, and devices at the Electronics and Telecommunications Research Institute toward the next generation of stereoscopic images.

Fluorescent Properties of Daehwangjam, Golden Silk, and Juhwangjam and Their Diminishing upon HCl Vapor Exposure

  • Rakesh K. Jha;Seong-Wan Kim;Sunghwan Kim
    • International Journal of Industrial Entomology and Biomaterials
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    • v.48 no.1
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    • pp.19-24
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    • 2024
  • For over five millennia, humans have benefited from the valuable byproducts of Bombyx mori silkworms nourished on mulberry leaves and a multitude of potential applications remains available due to the diverse array of silkworm varieties. In this work, we discuss the utilization of Daehwangjam (DHJ), golden silk (GS), and Juhwangjam (JHJ), distinctive colored silks found in Korea, as chemosensors. These novel silks emit fluorescence under external stimuli and show a diminishing fluorescence intensity when exposed to HCl vapor. The considerable surface-to-volume ratio of these cocoons allows for the identification of 5 ppm, 300 ppm, and 3000 ppm HCl vapors through decreased fluorescence intensity. The results show the suitability of natural DHJ, GS, and JHJ for applications in biosensing applications.

We-Human -Being Together of the Lives (우리 - 사람 -생명들의 더불어 있음에 관해서)

  • Kim, Yeran
    • Korean journal of communication and information
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    • v.70
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    • pp.132-164
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    • 2015
  • The formation of knowledge of the people of Korean society is the social practices of collective subjectivity. Subjectivity is the truth of the self, which is incessantly created, questioned and modified in the milieu of self-reflection. In an attempt to examine the hermeneutics of the subject of Korean society, a conceptual framework is proposed, which, with the notion of life embedded, consists of a historical sequence of the popular, minjung, multitude, people and community. The period of 1960s saw the ambiguous mass of lifes floating, the individual with his/her own interior world of consciousness emerge. The ideological solidarity is formed in the the next two decades, in contestation with immediate and physical threatening such as poverty and dictatorship. The democratization of Korean society and the global expansion of neoliberal regime gave a re-birth of multitude and people which is characterized with their pursuit of the co-existence and co-realization of singularity and universality on the ethical principle of the open and communicative radicality.

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A Study on the Effect of Skin Management which is based on the Lifestyle of Middleaged and Old Age Women (중.노년층 여성의 라이프스타일에 따른 외모 관리 효과에 관한 연구 - 피부 관리 효과를 중심으로 -)

  • Lim, Hee-Kyung;Choi, In-Ryu
    • The Research Journal of the Costume Culture
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    • v.18 no.4
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    • pp.670-686
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    • 2010
  • This study aims at clarifying the action types of skin management which is base on age, marriage or not, family composition, school career, and income which are demographic variables centering around the lifestyle of middleaged and old age women. As for study method, this researcher executed literature study and questionnaire on adult women over 45 years old who dwell in Seoul and Kyounggi area. Survey period was Mar. 1, 2009 to Jun. 30. And, after distributing 1,000 copies of questionnaire, this researcher used effective 869 copies of questionnaire for analysis out of collected questionnaire, 895 copies. As for analysis method, this researcher executed DUNCAN test with factor analysis, reliability analysis, manin component analysis, K-average, multitude analysis, dispersion analysis and post verification by using SPSS 12.0 program. As for demographic feature for middle aged and old age women, 50~59 years old women were most by age as 302 persons(33.7%). It is emerging that spouse existence is very high as 674 persons(75.3%) in the answer for marriage or not, couple family to live with unmarried children is very high as 483 persons(54.0%) in the answer for family composition, leaving high school in mid-course or gradation of high school are very high as 356 persons(39.8%) in the answer for school career, income from 3 million Won under 4 million won is very high as 260 persons(29.1%) in the answer for monthly income of family members, and women to use under 50 thousand won is very high as 510 persons(57.0%) in the monthly average expense to be used for skin management. In this study, this researcher extracted total 5 factors (economic saving, displaying consumption, confidence inclination, centering around family, and leisure application) by executing factor analysis with 12 question items of lifestyle so as to grasp factor structure of lifestyle of middleaged and old age people, and whole explanatory variable quantity was 70.9%. This researcher named as economic saving type, diplaying consumption style, and type centering around leisure and family, after making multitude analysis about 5 factors analyzed by measuring lifestyle feature. As the result of structure analysis of question items of skin management(pursuit of skin management, life of skin management, and inclination of skin management), this researcher extracted total 3 factors, and whole explanatory variable quantity was 71.30%. Thus, it emerged that there is significant difference among groups.

Magical Realism and Antonio Negri's Theory of Art: In Light of Claire Denis' Film Vendredi Soir (마술적 리얼리즘과 네그리의 예술론: 끌레어 드니의 영화 <금요일 밤>에 비추어)

  • CHOI, Soo Im
    • Cross-Cultural Studies
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    • v.34
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    • pp.7-41
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    • 2014
  • This article examines magical realism in contemporary european film, which is considered to be one of the most popular styles in the present culture, with regards to Antonio Negri's theory of art. Magical realism is "alternative approach to reality" (Maggie Ann Bowers, Magic(al) Realism) and defined as "a fictional technique that combines fantasy with raw physical reality or social reality in a search for truth beyond that available from the surface of everyday life" (Joan Mellen, Magic Realism). The term of Magic Realism was coined in 1923 by Franz Roh, German art historian, as the concept for the post-expressionist painting in Germany. It has flourished in the Latin-American literature during the 1950s to 1980s and spread worldwide. Since 1980s magical realism is considered to be a universal artistic mode. Since 1990s magical realism is to find in the various novels, and since 2000 one encounters magical realism in the cinema very often. Antonio Negri writes about the relationship between life, imagination, art and the political in his book Art et Multitude. According to Negri, the hard life of people in the present society liberates the imagination and this creates the art as "the excess of the existence". In this process the aesthetic becomes to the political. Negri calls this space of art as "magical time and space". Claire Denis' film Vendredi Soir is analyzed as a contemporary magic realist text, which realizes Negri's concept of art: vendredi soir (friday night) in Vendredi Soir is the magical time, when the impossible becomes the possible, and paris in the public transportation strike is the magical space, where the individuals meet the other in a new situation. The film analysis associates itself with Negri's theory of art: in Vendredi Soir, it is to see, that the excess of the existence liberates imagination and creates the magic reality both in the movements of things and the human relationship. The phenomenon of magical realism in contemporary culture can be understood as the symptom of the emotional and existential pains of contemporary people in the current world. The contemporaneity of the magical realism can be read in the film as "the metaphor for contemporary thought" (Alain Badiou, Cinema). As Antonio Negri writes, art can become "the aesthetic redemption" (Negri, Art et Multitude) for us. At the same time "(t)his is where aesthetics can be transformed into the political." (Lee, "Communism and the Void")