• Korean Journal of Plant Resources
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• v.7 no.2
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• pp.149-150
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• 1994

The plants medicinal resouces of middle area of Korea were investigated 10 times from May 1, 1993 to November 30. 1994. In order to analyze the vegetation of middle wild plants structure and distribu-tion. Medical wiId plants of middle southern area consisted of 100 familis, 380 specis in all. Theresources of important herb drugs were Polypodiaceae, Graminae, Liliaceae, Polygonaceae,Ranunculaceae, Brassicaceae, Rosaceae, Fabaceae, Apiaceae, Labiatae, Solanaceae, Scrophulariaceae,Campanulaceae, Compositae. The herb drugs were comparatively more than in other mountains in ourcountry.

• Korean Journal of Plant Resources
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• v.5 no.2
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• pp.113-127
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• 1992

The plants medicinal resources of southern area(Soraksan, Bughansan, Odesan, Gwanagsan, Sollaegsan, Gyeryongsan, Sogrisan, Deogyusan, Chinsan, Jogyesan, Mudeungsan, Hallasan) ofkorea were investigated 10 times from May 1,1992 to November 30,1992In order to analyze the vegetation of southem area, medical wild plants structure and distr:~bution.Medical wild plants of southern area consisted of 94 familis,284 specis in all. The resources of impor-tant herb drugs were Polypodiaceae, Graminea, Liliaceae, polygonaceae, Ranunculaceae,Brassicaceae, Rosaceae, Favaceae, Apiaceae, Ldbiatae, Solanaceae, Companulaceae, Compositae.The herb drygs were comparatively more thanin other mounteins in our country.

• Journal of the Korean Society of Food Science and Nutrition
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• v.27 no.6
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• pp.1177-1182
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• 1998

The antimutagenic and cancer cell growth inhibitory effects of woorimil contained herb and seaweed powders were examined. While woorimil itself showed only 40% antimutagenic effect on S. typhymurium TA98 against 4NQO(0.15 g/plate), water extracts of mountain herbs and seweeds including Comfrey, wormwood, Kale, Angelica utilis and pine leaves showed 80~90% antimutagenicity. On the other hand, these extracts along with woorimil showed 68 to 80% antimutagenic activities. Low antimutagenic activities of less than 50% were shown when these extracts were tested on TA98 against Trp P 1(0.5 g/plate), but high antimutagenic activities of 80~93.3% were shown on TA100. Water extracts of Capsella bursa pastoris and Allium grayi exhibited 60~80% of the activites in cytotoxicity tests of woorimil water extracts(0.5mg/ml) on human lung carcinoma cell. A549 showed 10% cell growth inhibitory effect. When mixed with Comfrey and Angelica utilis extracts, it showed 23~25% inhibition and other extracts showed only 12~23% inhibition. Cytotoxicity test of woorimil extracts on human liver cancer cell Hep3B revealed 20% inhibition. The additions of pine needle extracts, Angelica utilis and Comfrey showed 33%, 29% and 25% inhibition, respectively. But other extracts showed only 20% inhibition.

• Korean Journal of Plant Resources
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• v.3 no.1
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• pp.41-63
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• 1990

The plants medicinal resources of Mt. Chu-woL were investigated 21times from APril, 1975 to August , 1977 and from JuLy, 1988 to August 1989In orther to analyze the vegetation of Chu-woL mountain area , medical wildplants structure and distribution. MedicaL wild plants of Chu-woL moun-tain consisted of 113 familis, 428 species in alL. The resources of important herb drugs were Polypodiaceae, Graminea, Liliaceae , Polygonaceae,Ranunculaceae, Brassicaceae, Rosaceae , Fabaceae, Apiaceae, tabiatae, so-lanaceae, Scrophulariaceae, Campanulaceae, Compositae. The herb drugswere comparatively more than in other mountains in our country .

• Journal of Environmental Impact Assessment
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• v.19 no.6
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• pp.527-537
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• 2010

This study are Geumjung mountain fortress of the Busan Metropolitan City in the north gate of the East gate around the trail to identify the vegetation structure importance value, dominance, species diversity, similarity index analysis. Results of the study, plot on the western slopes elevation 423-636m, slopes of $15{\sim}20^{\circ}$ slope areas, Pinus densiflora, Pinus thunbergii, Quercus acutissima, Pinus thunbergii, Pinus rigida, Carpinus coreana, Quercus mongolica are fulfilling a community. Trees layer a height 8~12m, coverage 40~70%, sub-trees layer the height 3~7m, coverage 10~80%, shrubs layer the height 0.8~1.5m, coverage 20-30%, herb layer the height 0.1~0.5m, coverage 5-10% were in the range of plot in the east slope elevation 452-647m, slopes in the slope of $5-30^{\circ}$ and Pinus rigida, Pinus thunbergii, Pinus densiflora, Quercus mongolica, Quercus dentata, Carpinus coreana is fulfilling a community. The trees layer height 8~13m, coverage 0~70%, sub-trees layer the height 2~6m, coverage 0~80%, shrubs layer the height 0.8~1.5m, coverage 20-40%, herb layer the height 0.1-0.5m, coverage 5-40% were in the range. The survey showed to be in relatively good vegetation, but in some areas of Pinus rigida, Quercus acutissima, as was predicted in succession, the shrub layer in the plot of some dominated vine plants and vegetation management will be needed for this purpose respectively.

• Microbiology and Biotechnology Letters
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• v.47 no.2
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• pp.201-210
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• 2019

Biotransformation of ginsenosides by microorganisms alters the absorption and bioavailability of ginseng as a medicinal herb. In this study, we isolated two kinds of fermenting microorganisms from Eoyukjang, which is a traditional Korean fermented food made from soybean. Next, we identified and detected their ability to convert major ginsenosides to compound K. The two microorganisms, referred to as R2-6 and R2-15, had 100% similarity with Lactobacillus plantarum subsp. plantarum ATCC $14917^T$ and Lactobacillus rhamnosus JCM $1136^T$, respectively. The optimal pH and growth temperature of the isolates were determined to be pH 6-7 and $30^{\circ}C$. After fermentation for 30 days, the major ginsenosides in the mountain-cultivated ginseng were transformed to the highly bioactive ginsenoside, compound K, in the final product.

• Biomedical Science Letters
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• v.23 no.3
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• pp.277-280
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• 2017

Elsholtzia splendens, which grows on moist soil of mountainous regions, is widely distributed at all regions of Korea, especially at Mountain Ji ri. It is categorized as a Labiatae plant which is dried aerial part. It has the following medicinal properties; removal of fever, alleviation of pain, a good antiphlogistic agent as well as antibacterial effects. However, the effects of E. splendens on thrombosis and platelet activation are not precisely understood. We performed this study to develop antithrombotic agents from oriental medicine herb extracts. E. splendens inhibited platelet aggregation induced by arachidonic acid and U46619 in a concentration dependent manner. E. splendens did not show an effect on anticoagulation as determined by prothrombin time (PT) or activated partial thromboplastin time (aPTT). We also tested the effects of E. splendens using a carotid artery thrombosis rat model induced by 35% $FeCl_3$ treatment. E. splendens significantly inhibited thrombus weight compared with the control group. These results show that E. splendens may be developed as a potential antiplatelet activity agent for treatment of cardiocerebrovascular disease and atherosclerosis.

• The Korean Journal of Ecology
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• v.16 no.4
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• pp.377-395
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• 1993

Habitat types, community structure and population characteristics of Koelreuteria paniculata were investigated in Mt. Wolak, Chungbuk and Naesokdong, Daegu, which are natural habitats of the species in inland region of Korea, and its origin was discussed. Habitats of Koelreuteria paniculata were classified to 3 types: sand bar formed by the sands flooded in the course of flow of the mountain stream (Type 1). crevice on the rock bed within the mountain stream (Type 2) and crevice of the rock around the edge of mountain stream (Type 3). Most Koelreuteria paniculata communities in Mt. Wolak site were composed of 3 layers of subtree layer, shrub layer and herb layer and that of Daegu site was 4 layers including tree layer. In the floristic composition of the Koelreuteria paniculata community, plants occurring frequently in the wet and open site, such as Zelkova serrata and Fraxinus rhynchoph-vlla showed high frequency. Frequency distribution of diameter at ground surface of Koelreutrria paniculata showed reversed J-shaped type. It was supposed that expansion of Koelreuteria paniculata community in Mt. Wolak site might be accomplished by the flow of the stream. Many saplings capable of becoming a successor of mature trees in Daegu site in near degenerating phase were established on the forest floor of the Koelreuteria paniculata community. From this result, it was supposed that these saplings originated from the seeds dispersed from a seed tree might form the Koelreuteria paniculata community of the next generation. On the other hand, the origin of Koelreutevia paniculata in inland sites was explained by two hypotheses: the one was that Koelreuteria paniculata might be transplanted by human and the other was that the present site might be native habitat of the community.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.1
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• pp.92-97
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• 1997

Beverages using mountain edible herbs(MEH) were formulated by determining optimum ratio of juices of MEH to several other ingredients. Fermented beverages were made by mixing juices(1 volume) fermented with Lactobacillus helverticus with syrup(3 volumes), followed by homogenization and flavoring . The general analysis and quality change of the beverages during storage were Peformed. The analysis of the beverages showed that the pH of Synurus deltoides and Cirsium sctidens were 3.8 and 3.7, titratable acidities were 0.50 and 0.49, optical densities were 1.201 and 1.119, respectively, The pH and color were not significantly changed when Synurus deltoides and Cirsium sctidens were stored at room temperature and 37$^{\circ}C$ for 6 months. The pH of Synurs deltoides beverage ranged 3.95~3.96 and pH of Cirsium sctidens was 3.83~3.95 at room temperature and 3.87~3.98 at 37$^{\circ}C$, respectively. The analysis of fermented beverages showed that pHs of Synurus deltoides and Cirsium sctidens were 3.65 and 3.70, titratable acidities were 0.57 and 0.60. Solids-non-fat were 3.2 and 3.1, and total counts of lactic acid bacteria were 2.5$\times$10$^{8}$ and 4.0$\times$10$^{8}$ , respectively. The changes of pH and titratable acidities stored at 4$^{\circ}C$ for 15 days were 3.39~3.56 and 0.61~0.81 for Synurus deltoides and 3.48~3.67 and 0.60~0.78 for Cirsium sctidens, respectively.

• Journal of Ginseng Research
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• v.47 no.4
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• pp.561-571
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• 2023

Background: Escalating evidence shows that ginseng possesses an antiaging potential with cognitive enhancing activity. As mountain cultivated ginseng (MCG) is cultivated without agricultural chemicals, MCG has emerged as a popular herb medicine. However, little is known about the MCG-mediated pharmacological mechanism on brain aging. Methods: As we demonstrated that glutathione peroxidase (GPx) is important for enhancing memory function in the animal model of aging, we investigated the role of MCG as a GPx inducer using GPx-1 (a major type of GPx) knockout (KO) mice. We assessed whether MCG modulates redox and cholinergic parameters, and memory function in aged GPx-1 knockout KOmice. Results: Redox burden of aged GPx-1 KO mice was more evident than that of aged wild-type (WT) mice. Alteration of Nrf2 DNA binding activity appeared to be more evident than that of NFκB DNA binding activity in aged GPx-1 KO mice. Alteration in choline acetyltransferase (ChAT) activity was more evident than that in acetylcholine esterase activity. MCG significantly attenuated reductions in Nrf2 system and ChAT level. MCG significantly enhanced the co-localization of Nrf2-immunoreactivity and ChAT-immunoreactivity in the same cell population. Nrf2 inhibitor brusatol significantly counteracted MCG-mediated up-regulation in ChAT level and ChAT inhibition (by k252a) significantly reduced ERK phosphorylation by MCG, suggesting that MCG might require signal cascade of Nrf2/ChAT/ERK to enhance cognition. Conclusion: GPx-1 depletion might be a prerequisite for cognitive impairment in aged animals. MCG-mediated cognition enhancement might be associated with the activations of Nrf2, ChAT, and ERK signaling cascade.