• 한국응용곤충학회지
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• 제32권1호
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• pp.42-50
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• 1993

우리나라에 분포하고 있는 재래꿀벌(Apis cerana)의 일벌을 대상으로 춘계 11지역 및 하계 12지역 개체군을 선발하였으며, 총 47개 정량형질에 대해 지역별로 판별분석을 실시 하였고, 또한 양 계절간 변이도 분석하였다. 그 결과, 지역별 비교에서는 춘계 91.67%, 하계 88.44%의 평균분리율을 보였으며, 양계절간 비교에서는 97.58%로 나타났다. 반면에 양계절을 통합한 비교에서는 70.16%로 낮았다.

• Animal Systematics, Evolution and Diversity
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• 제15권2호
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• pp.165-174
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• 1999

동아시아의 한국과 중국에 살고 있는 붉은쥐속 (Apodemus) 5종 (A. agrarius, A. chevrieri, A. draco, A. latronum 및 A. peninsulae)의 표본들을 31개 외부 및 두골형질들의 수리분류학적 연구에 사용하였다. 2군과 각 군내의 8아군 [I; 큰 형; (A. agrarius chejuensis), (A. chevrieri), (A. draco orestes와 A. latronum) 및 (A. peninsulae peninsulae와 A. p. preator)], [ll; 작은형; (A. agrarius coreae), (A. agrarius manchuricus, A. a. ningpoensis 및 A. a. pallidior), (A. draco draco) 및 (A. peninsulae sowerbyi)]이 형성되었다. 형태형질의 분석에서 얻은 결론은 다음과 같다: 1) 형태형질들은 붉은쥐속 Apodemus내의 2아속 (Apodemus 와 Alsomys)을 구분하는 데에 유효하지 않다. 2) A. draco와 A. latronum가 동일한 종인지의 결정을 위한 계속적인 연구가 필요하다. 3) A. a. chejuensis는 본 연구에서 분석한 붉은쥐속 5종중에서 형태적 형질에서 가장 크기가 크다. 뿐만 아니라, 다음 사실들이 확인되었다 : 1) A. agrarius, A. chevrieri 및 A. peninsulae는 독특한 종들이다. 2) A. draco와 A.latronum는 흰넓적다리붉은쥐 A. peninsulae와 동종이 아니다. 3) 등줄쥐 A.agrarius의 3형(큰형, 중간형 및 작은형)은 3아종 [(A. a. chejuensis), (A. agrarius coreae) 및 ( A. a. manchuricus와 A. a. pallidior를 포함하는 A. a. ningpoensis]으로 구분된다. 4) A. draco draco와 A. draco orestes는 독특한 아종이다. 5) A. peninsulae peninsulae (A. p. preator포함)와 A. p. sowerbyi는 독특한 아종이다.

• 대한한방부인과학회지
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• 제19권1호
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• pp.47-68
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• 2006

Purpose : This study was carried out to investigate the effects of Gagamdokhwalgisang-Tang on the morphometric changes of femur, and on the hormones and cytokines associated with bone metabolism in overiectomized rats. Methods : Twenty-four female Sprague-Dawley rats were divided into sham operated group(normal) ovariectomized group(control), and treated with extract of GD group(treated). Each group was evaluated the changes of body weight at 0, 3, 6, 8 weeks after ovariectomy. Morphometric analysis(femur weight, femur/body weight ratio, femur ash weight femur ash/body weight ratio cross sectional area of compact bone and concellous bone of femur) and histopathological examination were performed at 8 weeks after ovariectomy. Estrogen, Alkaline Phosphatase(ALP) and cytokine(Tumor necrosis $factor-{\alpha}$, $Interleukin-l{\beta}$, Inerleukin-6) assay were performed at 8 weeks after ovariectomy. Results : 1. The body weight of control and treated group was significantly increased(p<<0.001) compared with the normal group at 8 weeks. 2. The femur weight and femur/body weight ratio of treated group were significantly increased(p<<0.05, p<<0.01) compared with the control group at 8 weeks. 3. The femur ash weight showed no significantly different changes, but femur ash/body weight ratio of treated group was significantly increased(p<<0.05) compared with the control group at 8 weeks. 4. In the cross sectional area of cancellous bone of femoral body, the treated group was significantly increased(p<<0.001) compared with the control group at 8 weeks. 5. The serum estrogen level of treated group showed no significantly different changes compared with the control group at 8 weeks. 6. The serum ALP activity of treated group was significantly decreased(p<<0.01) compared with the control group at 8 weeks. 7. The serum Tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ level of treated group was significantly decreased(p<<0.05) compared with the control group at 8 weeks. 8. The serum $Interleukin-l{\beta}(IL-1{\beta})$ level of treated group was significantly decreased(n<<0.001) compared with the control group at 8 weeks. 9. The serum Interleukin-6(IL-6) level of treated group was significantly decreased(P<<0.01)compared with the control group at 8 weeks. Conclusion : These results indicate that GD inhibits bone resorption in ovariectomized rats. And the major inhibitory mechanism may be related to the inhibitory effects of GD on the secretion of $TNF-{\alpha}$, $IL-1{\beta}$ and IL-6 in the pathogenesis of osteoporosis in estrogen deficient rats.

• 한국어류학회지
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• 제21권2호
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• pp.67-75
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• 2009

한국의 Cottus 속 어류 9개체군들의 형태 및 유전 변이를 서로 비교하였다. 형태변이 분석은 계수, 계측 형질 및 수정난의 크기를 분석하였으며, 유전 변이 분석은 AFLP fingerprinting을 이용하였다. 조사결과 동해로 흐르는 하천의 둑중개 집단은 서해와 남해로 흐르는 강 또는 하천의 둑중개 집단과 계측형질에서 유의적인 차이를 보였으나, 계수형질과 수정난 크기의 차이는 없었다. 하지만 배봉천의 Cottus sp. 집단은 계수형질에 있어 한둑중개와 비슷하였고, 배지느러미의 계측형질과 수정난의 크기는 둑중개와 비슷하였다. AFLP를 이용한 유전적 거리를 추정한 결과 둑중개 집단간 0.110~0.221로 나타났다. 한둑중개 집단과 둑중개 집단간 0.542~0.621로 나타났고, 배봉천의 Cottus sp. 집단과 둑중개 집단 간 0.222~0.304로 나타났다. UPGMA dendrogram결과 Cottus sp. 집단은 다른 둑중개 집단과 분리되었다.

• 대한한방부인과학회지
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• 제18권3호
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• pp.32-50
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• 2005

Purpose : This study was carried out to investigated the effects of Saenghyeolbosu-Tang on the morphometric changes of femur, and on the hormones and cytokines associated with bone metabolism in ovariectomized rats. Methods : Twenty-four female Sprague-Dawley rats were divided into sham operated group(normal), ovariectomized group(control), and treated with extract of Saenghyeolbosu-Tang group(treated). Each group was evaluated the changes of body weight at 0, 3, 6, 8, weeks after ovariectomy. Morphometric analysis(femur weight, femur/body weight, femur ash weight, femur ash/body weight, cross sectional area of compact bone and cancellous bone of femur) and histopathological examination were performed at 8 weeks after ovariectomy. Estrogen and cytokines($TNF-{\alpha},\;IL-1{\beta}$, IL-6) assay were performed at 8 weeks after ovariectomy. Results : 1. The femur weight(g) of treated group(1.59${\pm}$0.08) was significantly increased(p<0.05)compared with the control group(1.50${\pm}$0.07) at 8 weeks. 2. The femur/body weight(g) of treated group(5.27${\pm}$0.36) was significantly increased(p<0.05) compared with the control group(4.78${\pm}$0.37) at 8 weeks. 3. In the cross sectional area of cancellous bone of femur(${mm^2}$) the treated group(1.60${\pm}$0.20)was significantly increased(p<0.01) compared with the control group(1.19${\pm}$0.19) at 8 weeks. 4. The serum estrogen level(pg/ml) of treated(83.67${\pm}$27.44) and control group(800.49${\pm}$22.27)showed no significantly different changes at 8 weeks. 5. The serum $TNF-{\alpha}$ level(pg/ml) of treated(33.71${\pm}$6.43) and control group(41.35${\pm}$8.47) showed no significantly different changes at 8 weeks. 6. The serum $IL-1{\beta}$ level(pg/ml) of treated group(53.78${\pm}$10.83) was significantly decreased(p<0.001) compared with the control group(79.80${\pm}$11.40) at 8 weeks. 7. The serum IL-6 level(pg/ml) of treated group(55.52${\pm}$9.02) was significantly decreased(p<0.01) compared with the control group(69.69${\pm}$7.95) at 8 weeks. Conclusion : This study shows that Saenghyeolbosu-Tang inhibits bone resolution in ovariectomized rats. These results may be related to the inhibitory effect of Saenghyeolbosu-Tang on the secretion of $IL-1{\beta}$ and IL-6 in the Pathogenesis of　osteoporosis.

• 한국융합학회논문지
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• 제7권4호
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• pp.1-7
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• 2016

구조적 MRI 영상은 여러 단 변량과 다변량 방법을 위해 그레이 메터 (GM), 화이트 메터 (WM), 뇌척수액 (CSF) 세션화 과정을 하고 난후 형태계측학적 특징을 추출하기 위해 사용한다. 새로운 접근 방법은 매우 가벼운 알츠하이머 병에서 가벼운 알츠하이머병의 진단을 위해 적용된다. 간이정신상태검사에 따른 형태계측학적 특징과 가우시안 복합 모델 파라미터를 결합하여 정상인으로부터 알츠하이머 병 환자로 분류하는 방법을 제안한다. 결합한 특징은 주성분 분석 기법을 이용한 고차원의 저주를 제거한 후 다중 커널 SVM 분류기에 공급한다. 제안한 진단 방법의 실험적 결과는 90%이상의 특성도와 고민감도에 따라 다중 커널 SVM을 가진 층화 정확도가 96%까지 최대 산출한다.

• Imaging Science in Dentistry
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• 제41권2호
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• pp.71-78
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• 2011

Purpose : This study was performed to determine the optimal tile size for the fractal dimension of the mandibular trabecular bone using a tile counting method. Materials and Methods : Digital intraoral radiographic images were obtained at the mandibular angle, molar, premolar, and incisor regions of 29 human dry mandibles. After preprocessing, the parameters representing morphometric characteristics of the trabecular bone were calculated. The fractal dimensions of the processed images were analyzed in various tile sizes by the tile counting method. Results : The optimal range of tile size was 0.132 mm to 0.396 mm for the fractal dimension using the tile counting method. The sizes were closely related to the morphometric parameters. Conclusion : The fractal dimension of mandibular trabecular bone, as calculated with the tile counting method, can be best characterized with a range of tile sizes from 0.132 to 0.396 mm.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회 논문집
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• pp.199-203
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• 2005

지체시간은 중요한 수문학적 응답특성 중의 하나로서, 유역의 형태적 특성으로부터 영향을 받는 것으로 알려져 있다. 일반적으로 유역의 형상은 집수평면에 대한 각종 형상디스크립터를 통하여 표현할 수 있다. 본 논문에서는 최근 집수평면에 대한 새로운 형상지수로서 Moussa(2003)에 의하여 제안된 등가타원의 기하학적 특성을 지체시간 해석에 적용하였다. 강우-유출 관측자료의 지체시간은 Nash(1960)의 적률법을 이용하여 추정하였고. 우리나라의 3개 유역에 대한 사례분석을 통하여, 유역의 형태적 특성과 지체시간 사이의 관계를 분석하였다. 또한 상류지역으로부터 하류지역까지 등가타원의 형상이 변환되어 가는 양상을 고찰하였다. 그 결과, 등가타원을 기반으로 한 신집수형상디스크립터 a+b 및 $a+b+{\epsilon}OM$와 지체시간 사이에는 비교적 양호한 상관관계가 존재함을 확인할 수 있었고 등가타원의 형상은 하류방향을 따라 인의 형태로 접근해 감을 알 수 있었다. 또한 불규칙한 평면의 형상을 표현하기 위한 밀집도의 개념을 적용해 보고자 시도하였다.

• Journal of Korean Neurosurgical Society
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• 제58권5호
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• pp.454-461
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• 2015

Objective : In this study, we aimed to investigate the underlying ethiological factors in chiari malformation (CM) type-I (CMI) via performing volumetric and morphometric length-angle measurements. Methods : A total of 66 individuals [33 patients (20-65 years) with CMI and 33 control subjects] were included in this study. In sagittal MR images, tonsillar herniation length and concurrent anomalies were evaluated. Supratentorial, infratentorial, and total intracranial volumes were measured using Cavalieri method. Various cranial distances and angles were used to evaluate the platybasia and posterior cranial fossa (PCF) development. Results : Tonsillar herniation length was measured $9.09{\pm}3.39mm$ below foramen magnum in CM group. Tonsillar herniation/concurrent syringomyelia, concavity/defect of clivus, herniation of bulbus and fourth ventricle, basilar invagination and craniovertebral junction abnormality rates were 30.3, 27, 18, 2, 3, and 3 percent, respectively. Absence of cisterna magna was encountered in 87.9% of the patients. Total, IT and ST volumes and distance between Chamberlain line and tip of dens axis, Klaus index, clivus length, distance between internal occipital protuberance and opisthion were significantly decreased in patient group. Also in patient group, it was found that Welcher basal angle/Boogard angle increased and tentorial slope angle decreased. Conclusion : Mean cranial volume and length-angle measurement values significantly decreased and there was a congenital abnormality association in nearly 81.5 percent of the CM cases. As a result, it was concluded that CM ethiology can be attributed to multifactorial causes. Moreover, congenital defects can also give rise to this condition.

• Investigative Magnetic Resonance Imaging
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• 제19권1호
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• pp.1-9
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• 2015

Purpose: Several morphometric studies have been performed to investigate brain abnormalities in congenitally deaf people. But no report exists concerning structural brain abnormalities in congenitally deaf adolescents. We evaluated the regional volume changes in gray matter (GM) using voxel-based morphometry (VBM) in congenitally deaf adolescents. Materials and Methods: A VBM8 methodology was applied to the T1-weighted magnetic resonance imaging (MRI) scans of eight congenitally deaf adolescents (mean age, 15.6 years) and nine adolescents with normal hearing. All MRI scans were normalized to a template and then segmented, modulated, and smoothed. Smoothed GM data were tested statistically using analysis of covariance (controlled for age, gender, and intracranial cavity volume). Results: The mean values of age, gender, total volumes of GM, and total intracranial volume did not differ between the two groups. In the auditory centers, the left anterior Heschl's gyrus and both inferior colliculi showed decreased regional GM volume in the congenitally deaf adolescents. The GM volumes of the lingual gyri, nuclei accumbens, and left posterior thalamic reticular nucleus in the midbrain were also decreased. Conclusions: The results of the present study suggest that early deprivation of auditory stimulation in congenitally deaf adolescents might have caused significant underdevelopment of the auditory cortex (left Heschl's gyrus), subcortical auditory structures (inferior colliculi), auditory gain controllers (nucleus accumbens and thalamic reticular nucleus), and multisensory integration areas (inferior colliculi and lingual gyri). These defects might be related to the absence of general auditory perception, the auditory gating system of thalamocortical transmission, and failure in the maturation of the auditory-to-limbic connection and the auditorysomatosensory-visual interconnection.