• 한국환경복원기술학회지
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• 제15권3호
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• pp.29-43
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• 2012

This study evaluated 23 botanic gardens and arboretums under two main categories including professional group and operational group. As for professional group, the main difference between the functions of botanic gardens and arboretums was analyzed. In the case of operational group compared professional group respectively, on categories including importance of function and implementation, seeking to provide fundamental data of botanic gardens and arboretums by enhancing the quality of visitors and examining functional differences. The result of a difference in arboretums' function between professional and operational groups, the study analyzed the importance of botanic gardens and arboretums in terms of detailed categories such as research, education, collection, display, retention, and service for visitors. As a result, professional group showed retention 4.32>education 4.11>research 4.09>service for visitors 4.05, and operational group showed retention 3.70>service 3.52>education 3.41>research 3.37, indicating that both groups had retention as the most selected answer. Looking closely at the functions of the currently implemented detailed categories of botanic gardens and arboretums, such as research, education, collection, display, retention, and service for visitors, the study showed that 91.3% selected rare species and individual multiplication for research function, 78.3% chose education of natural ecosystem for children for education, 73.9% answered space for experiencing nature for display, and 73.9% also replied managon, diof rare species, reproduction, and retention of native plants' species for retention category, and service for visitors showed 95.7% for implementation. The study could not clearly point out the influence between predictors due to absence of an established comprehensive evaluation model. Also, it analyzed and reviewed comparison of functions of professional group and operational group, but in the future, it should conduct study on a systemic and objective classification of botanic gardens and arboretums to clearly examine the difference in views between groups, which also requires, at the same time, study on management policy of botanic gardens and arboretums or suggesting guidelines that suit types of forms, and also study on facilities and program development that can be applied to each class.

• 생약학회지
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• 제36권2호통권141호
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• pp.109-115
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• 2005

The herb of Allium victorialis var. platyphyllum (Liliaceae) has been used as an edible wild herb and to treat heart failure and gastritis. We have already reported antihyperlipidemic anti-tumor effects of this plant. To enlarge the commercial availability of this food, it was investigated whether the extracts of A. victorialis var. platyphyllum reduce hyperlipidemia and obesity or not. The plants tested in this experiment were collected from two eco-types of Is. Ullung and Mt. Odae cultivated at Pyongchang. Extracts were prepared by extracting the fresh leaves and those dried at $36^{\circ}C$ and $90^{\circ}C$, respectively. Pretreatment with the ethanolic extracts for two weeks(p.o.) reduced serum triglyceride-, total cholesterol- and LDL-cholesterol contents in rats induced by Triton WR-1339, respectively. Furthermore, oral administration of the extracts also inhibited the hyperlipidemia induced with oral diet of 30% corn oil. In the other attempt to find to alleviate the obesity, the model rats with obesity were induced by the high fat-diet for six weeks. Post-treatment with the extracts for two weeks significantly reduced the hyperlipidemia. Retroperitoneal-, epidymal- and total abdominal fat pad weights were considerably reduced at 100 mg/kg oral administration of the extracts. Increased feces lipid contents were also found in the rat treated with the extracts. The extract may lead to the higher activity in treatment of hyperlipidemia and obesity than of the dried one.

• 대한기계학회논문집A
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• 제35권11호
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• pp.1499-1506
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• 2011

초고온가스로로부터 생성된 $950^{\circ}C$ 정도의 초고온 열을 이용하여 수소를 경제적이며 또한 대량으로 생산하려는 원자력수소생산시스템에서 중간열교환기는 원자로에서 생산된 초고온 열을 수소생산 공장으로 전달하는 핵심 기기중의 하나이다. 한국원자력연구원에서는 초고온가스로에 사용될 핵심 기기에 대한 성능시험을 위해 소형가스루프를 구축하였고 중간열교환기의 유력한 형태로 고려되고 있는 인쇄기판형 열교환기의 소형 시제품을 제작하였다. 본 연구는 인쇄기판형 열교환기 소형 시제품을 소형가스루프에서 시험하기 전에 루프 시험조건하에서 인쇄기판형 열교환기 소형 시제품의 고온 구조건전성을 미리 평가하기 위한 작업의 일환으로 수행한 결과, 즉 고온 구조해석 모델링, 거시적 열 해석 및 구조 해석 결과 등을 정리한 것이다. 해석 결과는 인쇄기판형 열교환기 소형 시제품 성능시험결과외 비교하고 향후 제작될 중형 시제품 설계/제작에 반영할 것이다.

• 한국약용작물학회지
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• 제24권5호
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• pp.341-350
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• 2016

Background: Prenatal exposure to infectious and/or inflammatory insults can increase the risk of developing neuropsychiatric disorder such as bipolar disorder, autism, and schizophrenia later in life. We investigated whether Valeriana fauriei (VF) treatment alleviates prepulse inhibition (PPI) deficits and social interaction impairment induced by maternal immune activation (MIA). Methods and Results: Pregnant mice were exposed to polyriboinosinic-polyribocytidilic acid (5 mg/kg, viral infection mimic) on gestational day 9. The adolescent offspring received daily oral treatment with VF (100 mg/kg) and injections of clozapine (5 mg/kg) for 30 days starting on the postnatal day 35. The effects of VF extract treatment on behavioral activity impairment and protein expression were investigated using the PPI analysis, forced swim test (FST), open field test (OFT), social interaction test (SIT), and immunohistochemistry. The MIA-induced offspring showed deficits in the PPI, FST, OFT, and SIT compared to their non MIA-induced counterparts. Treatment with the VF extract significantly recovered the sensorimotor gating deficits and partially recovered the aggressive behavior observed in the SIT. The VF extract also reversed the downregulation of protein expression induced by MIA in the medial prefrontal cortex. Conclusions: Our results provide initial evidence of the fact that the VF extract could reverse MIA-induced behavioral impairment and prevent neurodevelopmental disorders such as schizophrenia.

• 대한두경부종양학회지
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• 제25권1호
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• pp.3-7
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• 2009

Background and Objectives : Panax ginseng C.A. Meyer is a medical plant that has been widely utilized as a tonic and nutritional agent since ancient times in Korea. Ginseng has anti-metastatic property of cancer and immunomodulating activity. The novel acidic polysaccharide compound(MB40) was isolated from the leaves of Panax ginseng C.A. Meyer. To determine immunomodulating activities of MB40, we evaluate anti-cancer and anti-metastatic effects of MB40 in tumor bearing immune competent mice. Material and Methods : C3H mice were divided into three equal groups(Cisplatin treatment group, MB40 treat-ment group, Cisplatin and MB40 treatment group) and were transplanted SCC(Squamous Cell Carcinoma) cells(2${\times}$106) to the lateral side of abdomen. From day 4 after transplantation, MB40 was administrated at dose of 10mg/kg, respectively, every other day by intratumoral injection. Cisplatin was systemically administrated at doses of 1mg/kg, respectively, every week by intraperitoneal injection. Results : 5 days after administration, tumors can be palpated in every mice group. After 13 days of administration, the mice group to which MB40 were administrated exhibited reduction in tumor size respectively, compared to cisplatin group. Overall status of mice such as body weight and activity were superior in MB40 group than cisplatin group. Conclusion : The result of this study indicates MB40 may have significant therapeutic effect and decreases complications induced by systemic chemotheraphy. MB40 may be developed as a novel and potent immunotropics to improve the cell immune system and anti-cancer drug for the treatment of cancer patients in head and neck squamous cell carcinoma.

• 대한디지털의료영상학회논문지
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• 제16권1호
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• pp.43-47
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• 2014

Sens of insecutity of the public and professionals about harmful effects of radiation is increasing in an accident at the Chernobyl and Fkushima nuclear power plant.Anxiety was amplified to lack of information about radiation majority of people. To target the middle and high school in the region of Daegu and Gyeongsangbuk-do, to investigate the radiation recognition of the next generation, it is intended to present a model of education for the safe use of radiation. The High School of the six metropolitan cities, city, town through the questionnaire and needs to be educational experience of radiation and use knowledge level of radiation, experience in daily life, understanding of man-made radiation and natural radiation, information channel on radiation, the radiation Distribute the total 800 parts of, to recover the 629 unit, was analyzed for 155 females 474 males. Many people 75.36% of the people, to 24.64% female subjects of this investigation, was constant, respectively from 13 to 18 years age. It is a large number and 30.37% of the respondents as "normal" level of knowledge of radiation, for the type of radiation, most knew. You have answer for risk experience of the medical radiation was higher, touching a lot of information via the broadcast medium in general, and the accuracy is low. I thought we wanted to be educated three or more twice a year, as an educator,about 71.37% and radiation-related understanding of knowledge and background in accordance with the diversification of information channels, the regional differences between urban and rural areas. But I considered the difference age (grade) for each is displayed, intended for junior high school students, the target surface and use the occurrence of radiation, high school students, the need for education about risk and application of radiation through this study.

• Journal of Radiation Protection and Research
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• 제22권4호
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• pp.309-317
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• 1997

비파괴적인 방법으로 방사성폐기물드럼에 대한 핵종분석을 수행할 때 드럼내 매질에 의한 방사선의 감쇠에 의해 핵종분석장치로 측정한 계수값은 실제 드럼내 방사능에 의한 계수값보다 작게 나타나 결과적으로 방사능의 측정결과가 과소평가된다. 그러므로 드럼내 매질에 의한 감쇠를 보정해 주어야 하는데 감쇠 보정방법은 드럼내 매질의 분포나 매질의 밀도에 따라 달리 적용해야 한다. 본 연구에서는 원자력발전소에서 발생하는 드럼 종류별로 모델드럼을 제작한 후 모델드럼에 표준감마선원을 넣고 핵종분석장치를 이용해 측정을 하여 드럼내 매질의 밀도를 구하였고, 이 값을 실제 매질의 밀도와 비교해 드럼종류에 따라 매질에 의한 최적의 감쇠 보정방법을 결정하였다. 그 결과 잡고체드럼의 경우에는 전송선원 보정방법과 평균밀도 보정방법, 차폐잡고체드럼의 경우 전송선원 보정방법과 두 감마선피크비교 보정방법이 최적의 감쇠 보정방법임을 알 수 있었고, 고밀도드럼인 폐수지, 농축폐액 및 폐필터드럼의 경우에는 평균밀도 보정방법과 두 감마선피크비교 보정방법을 사용해 드럼내 매질의 감쇠를 보정할 수 있다.

• Nuclear Engineering and Technology
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• 제40권6호
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• pp.451-458
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• 2008

After more than 10 years construction, KSTAR (Korea Superconducting Tokamak Advanced Research) had finally completed its assembly in June 2007, and then achieved the goal of first-plasma in July 2008 through the four month's commissioning. KSTAR was constructed with fully superconducting magnets with material of $Nb_3Sn$ and NbTi, and their operation temperatures are maintained below 4.5K by the help of Helium Refrigerator System. During the first-plasma operation, plasmas of maximum current of 133kA and maximum pulse width of 865ms were obtained. The KSTAR Integrated Control System (KICS) has successfully fulfilled its missions of surveillance, device operation, machine protection interlock, and data acquisition and management. These and more were all KSTAR commissioning requirements. For reliable and safe operation of KSTAR, 17 local control systems were developed. Those systems must be integrated into the logically single control system, and operate regardless of their platforms and location installed. In order to meet these requirements, KICS was developed as a network-based distributed system and adopted a new framework, named as EPICS (Experimental Physics and Industrial Control System). Also, KICS has some features in KSTAR operation. It performs not only 24 hour continuous plant operation, but the shot-based real-time feedback control by exchanging the initiatives of operation between a central controller and a plasma control system in accordance with the operation sequence. For the diagnosis and analysis of plasma, 11 types of diagnostic system were implemented in KSTAR, and the acquired data from them were archived using MDSpius (Model Driven System), which is widely used in data management of fusion control systems. This paper will cover the design and implementation of the KSTAR integrated control system and the data management and visualization systems. Commissioning results will be introduced in brief.

• 한국환경생태학회지
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• 제25권3호
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• pp.404-411
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• 2011

본 연구는 지속가능한 옥상녹화 식재계획을 위하여 관리조방형 옥상녹화 식재식물에 대한 다년간 조사결과를 토대로 피복률 변화의 양상을 분석하고 피복특성을 유형화하였다. 실험대상지는 2007년에 조성된 서울여자대학교 행정관 옥상녹화지이며 식물은 기린초 등을 포함한 4종류의 세덤류와 층꽃나무 등 다년생 초화류 14종을 포함하여 총 18종 이식재되었다. 식재식물 피복변화 모니터링은 2007년부터 2009년까지 3년간 실시하였다. 조사결과 피복률은 식재 후2년이 경과한 2008년에는 전반적으로 안정세를 보이거나 다소 증가한 반면 2009년 들어서는 세덤류와 섬백리향 등총 6종을 제외하고는 대다수 감소하는 양상을 보였다. 피복양상을 관찰한 결과 크게 4가지 유형으로 식재지유지형, 인접지역 잠식형, 포복 확산형, 산발 확산형으로 분류하였다. 또한 주요기간의 피복률 데이터를 종속변수로 하여 식재후 경과 시간과 단순회귀분석을 실시하였으며, 최종적으로 총 8종에서 통계적 유의수준 하에서 피복률 변화양상 예측모델이 도출되었다. 향후 다양한 식물들에 대한 장기적인 피복특성 모니터링을 통해 지속가능한 옥상녹화 식재계획을 위한 다양한 식물정보 구축이 필요할 것으로 생각된다.

• 한국식물학회:학술대회논문집
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• 한국식물학회 2002년도 춘계학술발표대회:발표눈문요지록
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• pp.62-72
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• 2002

This study has investigated the biosynthesis and function of the heavy metal binding peptides, the phytochelatins, in plants. PCs are synthesised enzymatically from glutathione by the enzyme PC synthase in the presence of heavy metal ions. Using Arabidopsis thaliana as a model organism cadmium-sensitive, phytochelatin-deficient mutants have been isolated and characterised in previous studies. The cadl mutants have wildtype levels of glutathione, are PC deficient and lack PC synthase activity. Thus, the CADl gene has been proposed to encode PC synthase. The CADl gene was isolated by a positional cloning strategy The gene was mapped and a candidate identified. Each of four cadl mutants had a single base pair change in the candidate gene and the cadmium-sensitive, cadl phenotype was complemented by the candidate gene. This demonstrated the CADl gene had been cloned. A homologous gene in the fission yeast, Schizosaccharomyces pombe was identified through database searches. A targeted-deletion mutation of this gene was constructed and the mutant, like cadl mutants of Arabidopsis, was cadmium-sensitive and PC-deficient. A comparison of the redicted amino acid sequences reveals a highly conserved N-terminal region Presumed to be the catalytic domain and a variable C-terminal region containing multiple Cys residues proposed to be involved in activation of the enzyme by metal ions. Similar genes were also identified in animal species. The Arabidopsis CADl/AtPCSl and S. pombe SpbPCS genes were expressed in E. coli and were shown to be sufficient for glutathione-dependent, heavy metal activate PC synthesis in vitro, thus demonstrating these genes encode PC synthase enzymes. Using RT-PCR, AtPCSl expression appeared to be independent of Cd exposure. However, at higher levels of Cd exposure a AtPCSl-CUS reporter gene construct appeared to be more highly expressed. Using the reporter gene construct, AtPCSl was expressed most tissues. Expression appeared to be greater in younger tissues and same higher levels of expression was observed in some regions, including carpels and the base of siliques. AtPCS2 was a functional gene encoding an active PC synthase. However, its Pattern of expression and the phenotype of a mutant (or antisense line) have not been determined. Assuming the gene is functional then it has clearly been maintained through evolution and must provide some selective advantage. This implies that, at least in some cells or tissue, it is likely to be the dominant PC synthase expressed. This remains to be determined