• Journal of Convergence for Information Technology
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• v.11 no.8
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• pp.53-61
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• 2021

The purpose of this study was to investigate the menstrual pain, clinical practice stress, and clinical competence and identify influencing factors of clinical competence of 3rd nursing students who start clinical practice for the first tim. The survey was conducted on 155 nursing students from June 1 to October 30, 2020. Data were analyzed using t-test, ANOVA, Scheffe test, Pearson correlation coefficients and multiple regression analysis. The degree of influence menstrual pain was 5.01points, clinical practice stress was 2.82points, clinical competence was 3.42points. Menstrual pain was positive correlated with clinical practice stress(r=.319, p=.000), and menstrual pain was negative correlated with clinical competence(r=-.279, p=.000). Clinical practice stress was negative correlated with clinical competence(r=-.333, p=.005). Menstrual pain was main factor that affects clinical competence. The model explained 25.0% of the variables. Therefore, intervention education is needed to reduce menstrual pain in order to improve the clinical competence of nursing students.

• Nuclear Engineering and Technology
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• v.53 no.6
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• pp.2000-2010
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• 2021

Mechanical moduli, such as Young's modulus (E), Bulks modulus (B), Shear modulus (S), longitudinal modulus (L), Poisson's ratio (σ) and micro Hardness (H) were theoretically calculated for (100-x)TeO₂+x MgO glasses, where x = 10, 20, 30, 40 and 45 mol%, based on the Makishima-Mackenzie model. The estimated results showed that the mechanical moduli and the microhardness of the glasses were improved with the increase of the MgO contents in the TM glasses, while Poisson's ratio decreased with the increase in MgO content. Moreover, the radiation shielding capacity was evaluated for the studied TM glasses. Thus, the linear attenuation coefficient (LAC), mass attenuation coefficient (MAC), transmission factor (TF) and half-value thickness (𝚫_0.5) were simulated for gamma photon energies between 0.344 and 1.406 MeV. The simulated results showed that glass TM10 with 10 mol % MgO possess the highest LAC and varied in the range between 0.259 and 0.711 cm^-1, while TM45 glass with 45 mol % MgO possess the lowest LAC and vary in the range between 0.223 and 0.587 cm^-1 at gamma photon energies between 0.344 and 1.406 MeV. Furthermore, the BXCOM program was applied to calculate the effective atomic number (Z_eff), equivalent atomic number (Z_eq) and buildup factors (EBF and EABF) of the glasses. The effective removal cross-section for the fast neutrons (ERCSFN, ∑_R) was also calculated theoretically. The received data depicts that the lowest ∑_R was achieved for TM10 glasses, where ∑_R = 0.0193 cm² g^-1, while TM45 possesses the highest ERCSFN where ∑_R = 0.0215 cm² g^-1.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.5
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• pp.85-95
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• 2021

Structure design sensitivity was evaluated using the orthogonal array experimental method for passive-type deck support frame (DSF) developed for float-over installation of the offshore plant. Moreover, approximation characteristics were also reviewed based on various meta-models. The minimum weight design of the DSF is significantly important for securing both maneuvering performance and buoyancy of a ship equipped with the DSF and guaranteeing structural design safety. The performance strength of the passive type DSF was evaluated through structure analysis based on the finite element method. The thickness of main structure members was applied to design factors, and output responses were considered structure weight and strength performances. Quantitative effects on the output responses for each design factor were evaluated using the orthogonal array experimental method and analysis of variance. The optimum design case was also identified from the orthogonal array experiment results. Various meta-models, such as Chebyshev orthogonal polynomial, Kriging, response surface method, and radial basis function-based neural network, were generated from the orthogonal array experiment results. The results of the orthogonal array experiment were validated using the meta-modeling results. It was found that the radial basis function-based neural network among the meta-models could approximate the design space of the passive type DSF with the highest accuracy.

• Journal of Korea Trade
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• v.24 no.8
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• pp.63-80
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• 2020

Purpose - Recent empirical studies have shown that FDI is expected to be strongly associated with democratic governance, political stability, and sound macroeconomic conditions of the host country. We attempt to take it a step further to see if governments implement a major change in institutional characteristics, will the institutional reform toward better governance have a substantive effect in enhancing FDI inflows. This paper thus aims to analyze the importance of good governance as an important factor in the attractiveness of FDI inflows in ASEAN+3 (Korea, China, Japan) countries. Design/methodology - To determine the effects of good governance on FDI inflows across ASEAN+3 countries recorded between 1996-2018, the Worldwide Governance Indicators (WGI) are used to investigate the impact of good governance on FDI inflows. The model has been estimated by using fixed effects to show the robustness of the results. Findings - Our main findings can be summarized as follows: Political Stability, Rule of Law, and Voice and Accountability have a statistically significant impact on the inflow of FDI in the ASEAN+3 Countries, especially for Korean economy. Moreover, GDP growth continue to exert their positive influence. However, Regulatory Quality, Government Effectiveness and Control of Corruption, though equally important, are insignificant to attract FDI inflows. The key finding is that good governance has a significant impact on inward FDI in the ASEAN+3 countries. Originality/value - Existing studies focus on the impact of political factors on FDI across countries. This paper instead attempts to investigate which type of good governance is the most important in promoting FDI inflows across ASEAN+3 countries, which is essential for multinationals to consider when choosing a foreign site as a possible FDI destination.

• Journal of Korea Trade
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• v.24 no.6
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• pp.173-193
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• 2020

Purpose - This study aims to examine the effect of entrepreneurship of start-ups on export performance when the business closure rate is higher than business start-up rate in Korea. Thus, this study analyzes various factors for start-ups established within the past seven years and uses export performance as an indicator. Prior to analysis of factors, the study defines the concepts of start-up factors based on various studies. Design/methodology - In order to analyze the export performance of startups, this study conducted an empirical analysis using statistical analysis. Theories were established based on previous studies, and hypotheses and research models were designed based on the established theories. Subsequently, in order to verify the research hypothesis and research model, factor analysis such as validity and reliability, and structural equation modeling were analyzed. Findings - As a result of analysis based on previous studies, we found that there is a difference between theoretical and practical aspects. Whereas previous studies showed that market orientation, technology orientation, and social capital have a direct impact on export performance, the present study analyzed that there is no such impact, and that technology capabilities were important as a result of the unique traits of start-ups. Originality/value - Existing studies have limitations in understanding the overall characteristics of a company by using market orientation, technology orientation, and social capital as individual independent variables. In addition, the existing researches have been analyzed in relation to corporate performance, whereas this study has been limited to export performance, so it can be regarded as different from other studies.

• Biomolecules & Therapeutics
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• v.29 no.3
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• pp.331-341
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• 2021

Liver cancer is a common tumor and currently the second leading cause of cancer-related mortality globally. Liver cancer is highly related to inflammation as more than 90% of liver cancer arises in the context of hepatic inflammation, such as hepatitis B virus and hepatitis C virus infection. Despite significant improvements in the therapeutic modalities for liver cancer, patient prognosis is not satisfactory due to the limited efficacy of current drug therapies in anti-metastatic activity. Therefore, developing new effective anti-cancer agents with anti-metastatic activity is important for the treatment of liver cancer. In this study, SP-8356, a verbenone derivative with anti-inflammatory activity, was investigated for its effect on the growth and migration of liver cancer cells. Our findings demonstrated that SP-8356 inhibits the proliferation of liver cancer cells by inducing apoptosis and suppressing the mobility and invasion ability of liver cancer cells. Functional studies revealed that SP-8356 inhibits the mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways, which are related to cell proliferation and metastasis, resulting in the downregulation of metastasis-related genes. Moreover, using an orthotopic liver cancer model, tumor growth was significantly decreased following treatment with SP-8356. Thus, this study suggests that SP-8356 may be a potential agent for the treatment of liver cancer with multimodal regulation.

• Nutrition Research and Practice
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• v.15 no.3
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• pp.319-328
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• 2021

BACKGROUND/OBJECTIVES: Curcuma zedoaria R. (Zingiberaceae) has been used to treat headache, fever, and hypertension-related symptoms in Asian countries, including Korea, China, and Japan. We investigated whether dietary intake of a C. zedoaria extract (CzE) affected atherosclerosis in vivo. MATERIALS/METHODS: Apolipoprotein E-deficient (ApoE^-/-) mice (n = 32) were fed a normal diet (ND), a high-cholesterol diet (HCD), an HCD containing CzE (100 mg/kg/day), or an HCD containing simvastatin (10 mg/kg/day) for 12 weeks. The anti-atherosclerotic effects were evaluated by observing changes in fatty streak lesions, immunohistochemical analysis, ex vivo fluorescence imaging, lipid profiles, and western blot analysis. RESULTS: The CzE-fed group showed a 41.6% reduction of atherosclerosis. Furthermore, CzE significantly reduced the levels of serum triglyceride, high-density lipoprotein, the chemokine (C-X3-C-motif ) ligand 1, the adhesion molecules vascular cell adhesion molecule-1, intracellular adhesion molecule-1, and E-selectin; down-regulation of tumor necrosis factor-α, interleukin-6, high mobility group box-1, and cathepsin levels in the aortic sinuses and aortas of ApoE^-/- mice were also observed. CONCLUSIONS: The results suggest that the inclusion of a water extract of C. zedoaria in a HCD is closely correlated with reducing the risk of vascular inflammatory diseases in an ApoE mouse model.

• Journal of Korea Trade
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• v.24 no.8
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• pp.189-206
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• 2020

Purpose - This paper attempted to verify the process by which a multinational corporation (MNC)'s subsidiary practices entrepreneurship to create effective knowledge (KC) in the local market. We have looked at whether subsidiary entrepreneurship (SENT) has a moderation effect in creating knowledge for the local market when a subsidiary has been given autonomy (AUT) from the headquarters (HQ). We also argue that when a subsidiary creates meaningful knowledge, the effect of the increased status by the HQ within the MNC network position (NP) has an indirect effect on whether knowledge is transferred to other overseas subsidiaries (KTO). Design/methodology - This paper used a structural equation model (SEM) of 282 effective foreign companies invested in Korea. To test the hypothesis about the process of SENT on KTO, descriptive statistics, confirmatory factor analysis, reliability, convergent and discriminant validities, and common method bias were analyzed using STATA. In addition, the moderation effect was verified along with SEM. The moderation effect of AUT on SENT and KC was presented graphically by confirming \mathrm{\pm1} standard deviation of AUT for the main effect. Findings - Our findings are as follows. First, while the hypothesis about the direct effect of SENT and KC on KTO was not supported, all other hypotheses were supported. Second, both the AUT and moderating effect and the indirect effect of NP were significant. In the conclusion, these findings are discussed in relation to its various theoretical and practical implications. Originality/value - This study attempted to contribute to the knowledge creation theory of MNC by contemplating how subsidiaries can move away from HQ and grow in the local market. Although there is still a shortage of foreign investment in the Korean market, our practical implications offer guidance for how current subsidiaries can develop more than other overseas subsidiaries.

• Structural Engineering and Mechanics
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• v.80 no.5
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• pp.491-501
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• 2021

A difference in subgrade settlement between two rails of a track manifests as lateral differential subgrade settlement. This settlement causes unsteadiness in the motion of trains passing through the corresponding area. To illustrate the effect of lateral differential subgrade settlement on the dynamic response of a vehicle-track coupling system, a three-dimensional vehicle-track-subgrade coupling model was formulated by combining the vehicle-track dynamics theory and the finite element method. The wheel/rail force, car body acceleration, and derailment factor are chosen as evaluation indices of the system dynamic response. The effects of the amplitude and wavelength of lateral differential subgrade settlement as well as the driving speed of the vehicle are analyzed. The study reveals the following: The dynamic responses of the vehicle-track system generally increase linearly with the driving speed when the train passes through a lateral subgrade settlement area. The wheel/rail force acting on a rail with a large settlement exceeds that on a rail with a small settlement. The dynamic responses of the vehicle-track system increase with the amplitude of the lateral differential subgrade settlement. For a 250-km/h train speed, the proposed maximum amplitude for a lateral differential settlement with a wavelength of 20 m is 10 mm. The dynamic responses of the vehicle-track system decrease with an increase in the wavelength of the lateral differential subgrade settlement. To achieve a good operation quality of a train at a 250-km/h driving speed, the wavelength of a lateral differential subgrade settlement with an amplitude of 20 mm should not be less than 15 m. Monitoring lateral differential settlements should be given more emphasis in routine high-speed railway maintenance and repairs.

• International Journal of Computer Science & Network Security
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• v.21 no.12spc
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• pp.703-711
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• 2021

The article is devoted to studying the development of scientific and methodological work and its impact on the quality of students' vocational training in higher pedagogical education institutions by applying information technology. The article aim is to development of the organizational methodological support and pedagogical diagnostics of the effectiveness of the project «Modelling scientific and methodological work in a higher education pedagogical institution by applying information technology » realization in the framework of increasing the level of scientific and methodological work in a higher education pedagogical institution as a factor contributing to enhancing the quality of pedagogical education. The research program of the project activity envisages stating and substantiating the problem of scientific and methodological work by applying information technology in the framework of increasing the level and quality of educational activities in a higher pedagogical education institution through the implementation of the project approach, developing a model for the system of organizational and methodological support of the project implementation as well as monitoring the process and evaluating the results of the project implementation in terms of developing teachers' scientific, methodological, information competency and enhancing students' progress in studying. The set of criteria were developed to evaluate the level of formation of scientific and methodological competency as a result of implementing the project for the development of scientific and methodological work. The scientific and methodological work by applying information technology in the academy was carried out in accordance with the following principles: systematic character, consistent diagnostics, practical focus, scientific organizational and methodological support.