• Geotechnical Engineering
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• v.6 no.4
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• pp.7-18
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• 1990

To deal with the case of a rigid retaining wall built close to a stable rock face with cohesionless backfill, analytical solution methods Proposed by Spangler- Handy and Sokolovskii are modified. The modified solution methods, taking into account different friction angles along the wall and the rock face, can estimate the developed static or dynamic horizontal earth pressures behind vertical retaining walls experiencing various types of outward wall movements. The range of application of each proposed method, which is represented by the ratio of the distance between the wall and the rock face to the height of the wall, is compared with each other and also is examined for different wall friction angles as well as soil friction angles. Further, the result predicted by the modified Spangler - Handy solution method is compared with that from the experimental model test on sand. The comparison shows in general good agreements at various stages of retaining wall rotation about its toe. Finally results of analytical parametric study, together with the design charts, are presented to demonstrate the effects of wall friction angles and horizontal acceleration coefficients.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.11
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• pp.1099-1104
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• 2012

The study investigates the mechanical deformation of a newly developed screwless omega-wire dynamic system for stabilization of the spine. The omega-wire spring stabilization system was tested under tension, compression, and dynamic compressive fatigue loads. In addition, its bending deformation was compared to that of a spiral-wire spring system using FEA. A model whose hanger inter-center distance is 60 mm showed an ultimate tensile stress of 3981.7 N at a displacement of 3.61 mm and an ultimate compressive load of 535.6 N at a displacement of 2.16 mm. Under fatigue loading of 5 Hz with 10 N/1 N, it did not show any failure over 5 million cycles, and the displacement was restricted to 8-9 mm. In the FEA, the omega-wire spring system showed more flexible bending features than did the spiral-wire spring system.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.5
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• pp.796-806
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• 2010

Atopic dermatitis induced NC/Nga mice were used to investigate the efficacy of BDH(Baedokhwan) on the recovery of dermatitic symptoms through its influence on the immune related factors and histological changes. First of all, BDH treated group showed improvement of atopic dermatitis with naked eye observation, and significant decrease of clinical index(CI) was observed after 14 weeks. And Infiltration of leukocytes was suppressed in BDH treated group, and the thickness of hypertrophied epidermis and dermis were decreased. In dorsal skin, BDH treated group showed significant decrease of the ratio of CD3+, CD11b+/Gr-1+ immune cells by 52.8%, 25.2, respectively. And also significant decrease the level of IL-5 mRNA and IL-13 mRNA by 44.4%, 28.0, respectively. In PBMC and serum, BDH treated group showed an decrease of CD4+/CD45+, B220+/CD23+, CD4+, CD8+, CD4+/CD25+ immune cells by 35.0%, 12.6%, 42.7%, 31.6% and 55.6%, respectively, and the level of histamine was decreased by 39.0%. The results above indicated that BDH clinically used for atopic dermatitis treatment has objective validity, and therefore can be provided as the basic data for anti-allergic and anti-inflammatory studies.

• Journal of Nutrition and Health
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• v.16 no.4
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• pp.296-302
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• 1983

The estimation of the nutritional requirements at the national or population level has a great difficulty in calculating the cumulative effects of the several variables, i. e. age, sex, weight activity, etc., in order to adapt nutrient requirements to the condition of a country or to a population group. The Joint FAO/WHO Expert Group on nutrient requirements had proposed a simpler model, an average daily per capita nutritional requirements that will enable the different parameters to incorporated in a single calculation table. The average daily per caita nutritional requirements for Korean-1982 calculated by this proposed method are as follows : energy, 2,200 kcal ; protein, 70g : calcium, 0.72g ; iron, 14mg; vitamin A, 1,900 IU ; ascorbic acid, 50mg ; thiamin, 0.9mg ; riboflavin, 1.2mg ; niacin equivalent, 15mg. The average daily per capita nutritional requirements would be used to assess the adequacy of the national dietary intakes and provide basic information for the establishment of national food production and consumption policies and the planning of programmes aiming at an adequate and equitable distribution of food supplies. On a different levels, they would be used widely in the planning of diets for a specific population group, and also provide important reference information for the epidemiology study of nutritional deficiencies.

• Korean Journal of Pharmacognosy
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• v.29 no.4
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• pp.283-292
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• 1998

The hemopoietic effects of deer blood (whole blood, blood cell, plasma, respectively) were examined using in vivo rat model. Experimental animals (Sprague-Dawley rat, male, 200 g) were divided into negative control group (injection of saline), positive control group (injection of Sipjeondaebotang) experimental groups (injection of whole blood, blood cell, plasma) and healthy control group. Cyclophosphamide(150mg/kg) was injected into experimental groups, negative and positive control group to induce bone marrow supression. After 8 days, freez dried deer blood (whole blood, blood cell, plasma respectively) and Sipjeondaebotang of 200 mg/kg in dose was administered orally into experimental groups and positive control group, once a day for 3 days (A group) and once a day for 12 days (B group) respectively. And then body weight and organ weight, biochemical profile (ALB, GOT, GPT, PRO, CRE), hematological values (WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT) and CBC differentiation (Neutro, Lymph, Mono, Reticulo) were carried out. Finally, platelets were specially increased in the plasma treated A group and reticulocytes were specially increased in the plasma treated B group.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.7
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• pp.685-691
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• 2011

The aim of this study is to point out the uniqueness of Doppler optical coherence tomography (DOCT) for use in a probe station for (in vivo) visualization of microscale flow and structure and to maximize the effectiveness of DOCT by overcoming its limitations. Conventional DOCT produces images of only one of the velocity components that is parallel to the incident light. In this study, a multi-angle DOCT to quantify a velocity vector field is proposed; this is an extension from a velocity scalar field to a vector field. Quantifying an instantaneous three-dimensional velocity field in a pulsating flow is another challenge because of its limited frame rate. The in-vivo pulsating blood flow is measured by using an electrocardiogram-gated multi-angle DOCT in a hamster cheek pouch model. It is shown that the aliasing problem caused by a relatively low frame rate is resolved by using this method of measurement.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.41 no.5
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• pp.329-339
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• 2017

Impingement jets have been applied in a wide variety of fields as they provide significantly high heat transfer on the impingement-jet stagnation zone. However, the crossflow in an impingement chamber developed by spent wall jets can disrupt and deflect the downstream jets in the array, leading to a decrease in the cooling performance of an array of impingement jets. A numerical analysis is made of the fluid flow and heat transfer characteristics in a corrugated structure that traps the spent air in the corrugations between impingement jets and reduces crossflow effects on downstream jets. All computations are performed by considering a three-dimensional, steady, and incompressible flow by using the ANSYS-CFX 15.0 code. The effects of the configuration parameters of the corrugated structure on crossflow reduction of the array of impingement jets are presented and discussed.

• Journal of Microbiology and Biotechnology
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• v.26 no.10
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• pp.1781-1789
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• 2016

Glargine insulin is a long-acting insulin analog that helps blood glucose maintenance in patients with diabetes. We constructed the pPT-GI vector to express prepeptide glargine insulin when transformed into Escherichia coli JM109. The transformed E. coli cells were cultured by fed-batch fermentation. The final dry cell mass was 18 g/l. The prepeptide glargine insulin was 38.52% of the total protein. It was expressed as an inclusion body and then refolded to recover the biological activity. To convert the prepeptide into glargine insulin, citraconylation and trypsin cleavage were performed. Using citraconylation, the yield of enzymatic conversion for glargine insulin increased by 3.2-fold compared with that without citraconylation. After the enzyme reaction, active glargine insulin was purified by two types of chromatography (ion-exchange chromatography and reverse-phase chromatography). We obtained recombinant human glargine insulin at 98.11% purity and verified that it is equal to the standard of human glargine insulin, based on High-performance liquid chromatography analysis and Matrix-assisted laser desorption/ionization Time-of-Flight Mass Spectrometry. We thus established a production process for high-purity recombinant human glargine insulin and a method to block Arg (B31)-insulin formation. This established process for recombinant human glargine insulin may be a model process for the production of other human insulin analogs.

• The Journal of the Korea Contents Association
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• v.17 no.11
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• pp.621-631
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• 2017

In March of 2014, after Eduwill's new TV commercial, Seo Kyung Seok, appeared as a model, unusually, various professional comedians have spontaneously made many TV ad parody contents. It is a kind of GCC (Gagman Created Contents), which is a content created by comedians if it is called User Created Contents (UCC) by a consumer voluntarily making contents. Various popular programs of TV stations such as tvN, KBS, SBS, MBC Eduwill TV commercial parody contents was broadcasted. Euduwill TV advertising parody contents can be classified as parody contents that mimic Eduwill CM songs and comic dancings by Seo Kyung Seok. In this study, we analyzed how the characteristics of class B culture such as 'twist' and 'satire' are reflected in Eduwill TV commercial parody, and discussed the correlation between advertisement, parody contents and socio-cultural phenomenon.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.6
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• pp.3725-3733
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• 2014

The purpose of this study was to determine the relationships among professional identity, role conflict and job satisfaction of nurses in and emergency department and to verify the factors that influence the job satisfaction. The subjects were 120 nurses in the emergency department of 2 tertiary hospitals and 5 secondary hospitals located in B city from July 1, 2013 to July 31, 2013. The professional identity and role conflict, and the professional identity and job satisfaction showed positive correlations. The factors influencing the job satisfaction were found to be the professional identity and 'hoping to work at an emergency department in the future'. The full explanatory power of the model was 13.0%. Therefore, participating in a symposium and specialty enhancing training will be needed to enhance the specialty of emergency department nurses.