• Title/Summary/Keyword: model B3

Search Result 3,811, Processing Time 0.031 seconds

Water soluble tomato concentrate regulates platelet function via the mitogen-activated protein kinase pathway

  • Jeong, Dahye;Irfan, Muhammad;Saba, Evelyn;Kim, Sung-Dae;Kim, Seung-Hyung;Rhee, Man Hee
    • Korean Journal of Veterinary Research
    • /
    • v.56 no.2
    • /
    • pp.67-74
    • /
    • 2016
  • Tomato extract has been shown to exert antiplatelet activity in vitro and to change platelet function ex vivo, but with limitations. In this study, antiplatelet activity of water soluble tomato concentrate (Fruitflow I) and dry water soluble tomato concentrate (Fruitflow II) was investigated using rat platelets. Aggregation was induced by collagen and adenosine diphosphate and granule-secretion, $[Ca^{2+}]_i$, thromboxane B2, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) levels were examined. The activation of integrin ${\alpha}_{IIb}{\beta}_3$ and phosphorylation of signaling molecules, including mitogen-activated protein kinase (MAPK) and PI3K/Akt, were investigated by flow cytometry and immunoblotting, respectively. Prothrombin time (PT) and activated partial thromboplastin time (aPTT) were examined. Moreover, in vivo thrombus weight was tested by an arteriovenous shunt model. Fruitflow I and Fruitflow II significantly inhibited agonist induced platelet aggregation, adenosine triphosphate and serotonin release, $[Ca^{2+}]_i$, and thromboxane B2 concentration, while having no effect on cAMP and cGMP levels. Integrin ${\alpha}_{IIb}{\beta}_3$ activation was also significantly decreased. Moreover, both concentrates reduced phosphorylation of MAPK pathway factors such as ERK, JNK, P38, and PI3K/Akt. In vivo thrombus formation was also inhibited. Taken together, these concentrates have the potential for ethnomedicinal applications to prevent cardiovascular ailments and can be used as functional foods.

Biomass and Net Primary Productivity of Pinus densiflora Natural Ecosystem in Kangwondo, Korea (강원도산(江原道産) 소나무천연림생태계(天然林生態系)의 Biomass 및 Net Primary Production에 관(關)한 연구(硏究))

  • Lee, Soo Wook
    • Journal of Korean Society of Forest Science
    • /
    • v.71 no.1
    • /
    • pp.74-81
    • /
    • 1985
  • Dimension analysis was used to estimate biomass and net primary production(NPP) in a 36-year-old Japanese red pine (Pines densiflora S. et Z.) natural forest in Kangwondo. Best estimation was made by the equation model of $Wt=aD^bH^c$ where Wt is weight in kg, D is DBH in cm, and H is total tree height in m. Total aboveground biomass was estimated at 198.82 t/ha. Organic matter was distributed in the Japanese red pine stand as follows ; bolewood 68.8%, live branches 16.5%, bolebark 5.4%, foliage 4.6%, dead branches 3.7%, and cones 0.6%. Net primary production was estimated at 15.87 t/㏊/yr and was distributed: bolewood 44.5%, live branches 30.9%, foliage 14.1%, current twig 7.1%, and bolebark 3.3%. Leaf efficiency was estimated at 1.876. The power equation for biomass and IVPP yielded similar results as the results for Pines densiflora in Japan.

  • PDF

Effect of Ignition Delay Time on Autoignited Laminar Lifted Flames (자발화된 층류 부상화염에 대한 점화지연시간의 영향)

  • Choi, Byung-Chul
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.35 no.10
    • /
    • pp.1025-1031
    • /
    • 2011
  • Autoignition characteristic is an important parameter for designing diesel or PCCI engines. In particular, diesel spray flames are lifted from the nozzle and the initial flame is formed by an autoignition phenomenon. The lifted nature of diesel spray flames influences soot formation, since air will be entrained into the spray core by the entrainment of air between the nozzle region and the lifted flame base. The objective of the present study was to identify the effect of heat loss on the ignition delay time by adopting a coflow jet as a model problem. Methane ($CH_4$), ethylene ($C_2H_4$), ethane ($C_2H_6$), propene ($C_3H_6$), propane ($C_3H_8$), and normal butane (n-$C_4H_{10}$) fuels were injected into high temperature air, and the liftoff height was measured experimentally. As the result, a correlation was determined between the liftoff height of the autoignited lifted flame and the ignition delay time considering the heat loss to the atmosphere.

Convective Heat Transfer Correlations for the Compact Heat Exchanger with Circular Tubes and Flat Tubes-Plate Fins (원형관 및 납작관-평판휜 형상의 밀집형 열교환기에 대한 대류열전달 상관관계식)

  • Moh, Jeong-Hah
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.34 no.3
    • /
    • pp.291-299
    • /
    • 2010
  • Aspect-ratio-based numerical analysis is carried out to investigate the air-side convective heat transfer characteristics in compact heat exchangers with circular tubes and flat tubes-plate fins. The RNG $k-{\varepsilon}$ model is adopted for turbulence analysis. The numerical analysis is carried out for aspect ratios ranging from 3.06 to 5.44 and for Reynolds numbers ranging from 1,000 to 10,000. The calculated results indicate a correlation between the friction factor and Colburn j factor in the compact heat exchanger system for the range of aspect ratios under consideration. The results obtained for circular tubes and flat tubes-plate fins in this study can be utilized to realize the optimal design of an air conditioning system.

The Simultaneous Determination of Chemical Ingredients in Silica Minerals by X-ray Fluorescence Spectrometry using Matrix Correction Method (매트릭스 보정법을 이용한 규산질 광물 중 화학성분의 X-선 형광분광법 분석)

  • Kim, Yeong Man;Choe, Beom Seok;Lee, Gyeong Mi;Kim, Seon Tae;Lee, Jong Uk
    • Journal of the Korean Chemical Society
    • /
    • v.34 no.1
    • /
    • pp.63-68
    • /
    • 1990
  • The chemical ingredients such as $SiO_2,\;Al_2O_3,\;MgO,\;Fe_2O_3,\;CaO$ and $TiO_2$in silica minerals were determined by X-ray fluorescence spectrometry using a matrix correction method. The synthesized standards mixed with reagent grade oxides and the sample were diluted by fusing with 16 times $Li_2B_4O_7$. The matrix effects correlated among the ingredients were corrected by the empirical coefficient method based on the Lucas-Tooth and Pyne model. The analytical results showed relatively good agreement between the different sets of coefficients but were improved with increasing the number of standard. The accuracy of this method was also examined with the standard reference material of NIST.

  • PDF

A Study on the Jacket Pattern for Elderly Women (노년여성을 위한 재킷패턴 연구)

  • Bae, Ju-Hyeong;Kim, In-Sook
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.31 no.7
    • /
    • pp.1008-1019
    • /
    • 2007
  • The purpose of this study was to develop an appropriate jacket pattern for elderly women over sixty years old, providing a good fit and appearance. Results were as follows: The length of the jacket was made long enough to cover the area 22.0cm below the waistline. The waist back length was made 1.7cm longer than the actual size of the waist back length. The armhole length was made 0.5cm longer than B/4, enhacing the appearance and functionality while allowing freer movement of the arms. As for the front and back interscye breadths, the front interscye breadth was made 1.7cm larger than the actual size while the back interscye breadth was only 1.0cm larger, providing the front interscye breadth more space. The bust breadth was made 10.0cm larger than the bust circumference measure(B/4+2.5cm), the waist breadth was made 6.0cm larger than the waist circumference measure(W/4+1.5cm), The hip breadth was made 12.0cm larger than the him circumference measure(H/4+3.0cm). The sleeve length was made 3.0cm larger than the arm length measure, as the sleeve length of a jacket is usually long enough to cover the ulnar styloid. The sleeve width was made 5.0cm larger than the upper arm circumference measure, as the upper arm circumference measure of the model pattern was too large than necessary, worsening the overall appearance. The sleeve cap height was set at AH/4+4.7cm. The wrist circumference of 27.0cm was set, allowing 2/3 and 1/3 for the large sleeve and small sleeve respectively.

Variation in seedling growth inhibition due to Maleic Hydrazide treatment of rice(Oryza sativa) and ragi(Eleusine coracana) genotypes and its relationship with yield and adaptability

  • Das, Swarnalata;Sinha, Susil Kumar;Misra, Rama Chandra
    • Journal of Crop Science and Biotechnology
    • /
    • v.11 no.3
    • /
    • pp.215-222
    • /
    • 2008
  • Multilocation trials on 36 rice(Oryza sativa) genotypes of 3 different maturity groups were conducted at four different locations of Orissa for 3 years and 30 ragi(Eleusine coracana) genotypes of 2 different maturity groups were evaluated in three environmental conditions for 3 years. Grain yield data were subjected to stability analysis following linear regression model to estimate adaptability and stability parameters, i.e. b, and $S^2d$ Stability of performance of genotypes was also estimated by two other stability parameters viz., ecovalence W and AMMI stability value ASV. The rice and ragi genotypes of different duration groups showed wide variation in their mean yield, b, $S^2d$, W and ASV parameters. Seeds of the 36 rice and 30 ragi genotypes were treated with 500 and 100 ppm aqueous solution of maleic hydrazide(MH) for 24 hours, respectively to study MH-sensitivity. Sensitivity of genotypes to MH treatment was estimated in terms of seedling growth inhibition index(SGI). The rice and ragi genotypes showed wide differences in their MH-sensitivity in terms of SGI. Relationship of MH-sensitivity of genotypes with their yielding ability, adaptability and stability of performance was tested by contingency $x^2$ test. Low sensitivity of rice and ragi genotypes to MH in terms of SGI appeared to be good indicators of high yielding ability of genotypes. Also, low and high MH-sensitivity of genotypes would be a good indicator of better adaptability to rich and poor environments, respectively, in ragi but not in rice. Low MH-sensitivity of genotypes could be the good indicator of stability of yield performance in rice but not in ragi.

  • PDF

Development of a One-Step Duplex RT-PCR Method for the Simultaneous Detection of VP3/VP1 and VP1/P2B Regions of the Hepatitis A Virus

  • Kim, Mi-Ju;Lee, Shin-Young;Kim, Hyun-Joong;Lee, Jeong Su;Joo, In Sun;Kwak, Hyo Sun;Kim, Hae-Yeong
    • Journal of Microbiology and Biotechnology
    • /
    • v.26 no.8
    • /
    • pp.1398-1403
    • /
    • 2016
  • The simultaneous detection and accurate identification of hepatitis A virus (HAV) is critical in food safety and epidemiological studies to prevent the spread of HAV outbreaks. Towards this goal, a one-step duplex reverse-transcription (RT)-PCR method was developed targeting the VP1/P2B and VP3/VP1 regions of the HAV genome for the qualitative detection of HAV. An HAV RT-qPCR standard curve was produced for the quantification of HAV RNA. The detection limit of the duplex RT-PCR method was 2.8 × 101 copies of HAV. The PCR products enabled HAV genotyping analysis through DNA sequencing, which can be applied for epidemiological investigations. The ability of this duplex RT-PCR method to detect HAV was evaluated with HAV-spiked samples of fresh lettuce, frozen strawberries, and oysters. The limit of detection of the one-step duplex RT-PCR for each food model was 9.4 × 102 copies/20 g fresh lettuce, 9.7 × 103 copies/20 g frozen strawberries, and 4.1 × 103 copies/1.5 g oysters. Use of a one-step duplex RT-PCR method has advantages such as shorter time, decreased cost, and decreased labor owing to the single amplification reaction instead of four amplifications necessary for nested RT-PCR.

Performance Analysis of Spread Spectrum Underwater Communication Method Based on Multiband (다중 밴드 기반 대역 확산 수중통신 기법 성능분석)

  • Shin, Ji-Eun;Jeong, Hyun-Woo;Jung, Ji-Won
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
    • /
    • v.13 no.5
    • /
    • pp.344-352
    • /
    • 2020
  • Covertness and performance are very important design goals in the underwater communications. To satisfy both of them, we proposed efficient underwater communication model which combined multiband and direct sequence spread spectrum method in order to improve performance and covertness simultaneously. Turbo coding method with 1/3 coding rates is used for channel coding algorithm, and turbo equalization method which iterately exchange probabilistic information between equalizer and decoder is used for receiver side. After optimal threshold value was set in Rake processing, this paper analyzed the performance by varying the number of chips were 8, 16, 32 and the number of bands were from 1 to 4. Through the simulation results, we confirmed that the performance improvement was obtained by increasing the number of bands and chips. 2~3 dB of performance gain was obtained when the number of chips were increased in same number of bands.

Link Availability of Satellite-to-ground Free-space Optical Communication Systems in South Korea (우리나라 위성-지상 하향 무선 광통신 시스템의 링크 가용성)

  • Kim, Gyuwan;Kim, Daeho;Vuong, V. Mai;Kim, Hoon
    • Korean Journal of Optics and Photonics
    • /
    • v.33 no.3
    • /
    • pp.113-121
    • /
    • 2022
  • We analyze the link availability of satellite-to-ground free-space optical (FSO) communication systems in South Korea. Using ten-year meteorological data for five major cities (Seoul, Busan, Daegu, Daejeon, and Gwangju), we theoretically predict the link availability from the power losses induced by absorption, scattering, aerosols, and scintillation in the atmospheric channel. For accurate but conservative estimation of the link availability determined by cloud cover, we propose a loss model based on the maximum value of cloud droplet concentration. The results show that the link availability ranges from 45% to 70% when a single ground station is placed in a major city in South Korea and a 20-dB link budget is allocated for atmospheric loss. However, the availabilities improve to 90% and 97% when 3- and 5-site diversities are employed, respectively.