• Transactions of the Korean Society of Automotive Engineers
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• v.20 no.4
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• pp.125-132
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• 2012

Urea-SCR system, which converts nitrogen oxides to nitrogen and water in the presence of a reducing agent, usually AdBlue urea solution, is known as one of the powerful NOx reduction systems for mobile as well as stationary applications. For its consistent and reliable operation in mobile applications, such various problems as transient injection, ammonia slip, and freezing in cold weather have to be resolved. In this work, therefore, numerical study on three-dimensional unsteady heating problems were analyzed to understand the melting and heat transfer characteristics such as urea liquid volume fraction, temperature profiles and generated natural convection behavior in urea solution by using the commercial software Fluent 6.3. After validating by comparing numerical and experimental data with pure gallium melting phenomena, numerical experiment for urea melting is conducted with three different coolant heating models named CH1, 2, and 3, respectively. Finally, it can be found that the CH3 model, in which more coolant is concentrated on the lower part of the urea tank, has relatively better melting capability than others in terms of urea quantity of $1{\ell}$ for start-up schedule.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.44 no.2 s.314
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• pp.47-59
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• 2007

Recently, Healthcare system has not been standardized and has been developed as an embedded system lacking interoperability. We are finally going to face such problems as having excessive load in using network caused by the uncontrolled spread of system and un-guaranteed interoperability among the heterogeneous systems. We suggest the possibility that OSGi and JADE can be accepted as a solution for the above problems.

• Biomolecules & Therapeutics
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• v.14 no.1
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• pp.40-44
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• 2006

Mirtazapine is an antidepressant agent with dual action on both the noradrenergic and serotonergic neurotransmitter systems. A simple high performance liquid chromatographic method has been developed and validated for the quantitative determination of mirtazapine in human plasma. A reversed-phase Cl8 column was used for the determination of mirtazapine with a mobile phase composed of 0.01M ammonium acetate solution (pH 4.2) and acetonitrile (75:25, v/v%) at a flow rate of 1.2 mL/min. Terazosin hydrochloride was used as an internal standard. The fluorescence detector was set at excitation and emission wavelengths of 290 and 350 nm, respectively. Intra- and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification of 3 ng/mL. Mirtazapine was stable in human plasma under various storage conditions. This method was used successfully for a pharmacokinetic study using plasma samples after oral administration of a single 30 mg dose as mirtazapine base to 8 healthy volunteers. The maximum plasma concentration of mirtazapine was $64.1{\pm}28.0ng/mL$ at 1.8 h, and the area under the curve and elimination half-life were calculated to be $674.1{\pm}218.5ng\;h/mL\;and\;23.4{\pm}3.8h$, respectively.

• International Journal of Internet, Broadcasting and Communication
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• v.7 no.1
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• pp.42-48
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• 2015

Generally, the current commercial cloud system is hosted by the centralization large datacenter. However, the other clouding forms existed and one of them is the P2P cloud. The P2P Cloud is a distributed systems, is freedom to join and leave and is possible to provide the IaaS. Commonly, P2P Cloud System is based on Pure-P2P System. Since a number of connection paths exist, it has a high reliability and easily scalability of the network. However, there are disadvantages of the slow rate of route because of looking up the all peers in order to search for the peer. In this paper, it proposes the P2P cloud system based on super-peer P2P. Super-peer P2P system has fast routing time, because of searching for cluster unit and it also can has high reliability and high scalability. We designs the super Peer cloud service and proposes the system model and Resource Allocation Algorithm for IaaS in Super peer P2P environment.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.945-948
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• 2011

기존의 모바일 IPv6에서 경로 최적화를 하기 위해 바인딩 업데이트를 할 때 RR 프로토콜을 사용한다. IPv6에서 바인딩 업데이트는 이동노드가 홈 네트워크에서 외부 네트워크로 이동했을 때 Home Agent와 Correspondent Node(CN)에게 전송하며 이 과정에서 몇 가지 취약점으 가지고 있다. HoIT와 CoIT 메시지는 서로 연관이 없으며 이동 단말과 HA사이에만 IPSec으로 보호된 터널이 존재하고 HA와 CN 사이에는 보호되지 않는다. 따라서 공격자는 CN과 가까이에 위치하여 자신의 CoA를 CN에게 CoIT를 보내 토큰을 받아서 CN과 바인딩 업데이트를 할 수 있다. 바인딩 업데이트가 끝나면 두 노드사이는 정상적인 통신을 할 수 있고 공격자에 의해 위험에 노출 될 수 있다. 또한 CoIT 메시지를 보내면 CN에서는 토큰을 생성하게 되므로 공격자가 다수의 기기를 획득해 CN에게 계속 CoIT를 보내면 계속 토큰을 만들어야 하므로 다른 정상적인 노드의 통신을 방해할 수 있다. 따라서 이 논문에서는 이러한 RR프로토콜에 대한 문제점을 분석하고 이러한 문제점을 해결 할 수 있는 개선 방안을 논의 해본다.

• Herbal Formula Science
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• v.21 no.1
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• pp.177-185
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• 2013

Objectives : Leejung-tang (Lizhong-tang) has been used for treatment of gastrointestinal disorders in Korea. In this study, we performed quantification analysis of five marker components, liquiritin, ginsenoside Rb1, ginsenoside Rg1, glycyrrhizin, and 6-gingerol in Leejung-tang using a ultra performance liquid chromatography- electrospray ionization-mass spectrometer (UPLC-ESI-MS). In addition, we evaluated antioxidant activity of Leejung- tang. Methods : The column for separation of five constituents used a UPLC BEH C18 ($100{\times}2.1mm$, $1.7{\mu}m$) maintained at $45^{\circ}C$. The mobile phase consisted of two solvent systems, 0.1% (v/v) formic acid in H2O (A) and CH3CN (B) by gradient flow. The flow rate was 0.3 mL/min with detection at mass spectrometer. The antioxidative activities conduct an experiment on 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities of Leejung-tang. Results : Calibration curves of five marker compounds were acquired with r2 values > 0.99. The amount of the five compounds in Leejung-tang were 0.07 - 0.84 mg/g. The concentration required for 50% reduction (RC50) against ABTS radical was 119.02 ug/mL. In addition, the scavenging against DPPH radical of Leejung-tang was 11.4%, 14.5%, 19.8%, 29.6%, and 49.2% at 25 ug/mL, $50{\mu}g/mL$, $100{\mu}g/mL$, $200{\mu}g/mL$, and $400{\mu}g/mL$, respectively. Conclusions : The established LC-MS/MS method will be helpful to improve quality control of Leejung-tang. In addition, Leejung-tang is a potential antioxidant therapeutic agent.

• Journal of Advanced Navigation Technology
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• v.15 no.4
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• pp.585-590
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• 2011

In the past few years, M2M (Machine-to-Machine) applications have become a hot topic in the wireless industry. While M2M applications can be used for many purposes (smart homes, smart metering/electricity meter reading, fleet management, mobile workforce, automobile insurance, vending machines, etc), and in many sectors (healthcare, agriculture, commercial, industrial, retail, utility, etc.), smart metering applications or smart grids present the biggest growth potential in the M2M market today. M2M platform is the future ubiquitous network technologies which provide the integrated service with the networks and devices. The promising technologies to tackle these problems are the Semantic technologies, for interoperability, and the Agent technologies for management of complex systems. In this paper the information communication technique based on the disaster prevention system's for the M2M, concepts and its requirement technology and application are studied.

• Journal of Ginseng Research
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• v.35 no.2
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• pp.138-148
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• 2011

Exponential rise in the use of mobile communication devices has generated health concerns due to radiofrequency (RF) exposure due to its close proximity to the head. Calcium binding proteins like calretinin regulate the levels of calcium ($Ca^{2+}$) which plays an important role in biological systems. Ginseng is known for maintaining equilibrium in the human body and may play a beneficial radioprotectant role against electromagnetic field (EMF) exposure. In the present study, we evaluated the radioprotective effects of red ginseng (RG) extract in a mouse model. Calretinin (CR) expression was measured using a free-floating immunohistochemical method in the hippocampus of mice after 835 MHz EMF exposure for 5 h/d for 5 d at specific absorption rate=1.6 W/kg for the different experimental groups. The control animals were treated with NaCl while the experimental animals received 10 mg/kg ginseng, or 30 mg/kg; EMF exposed mice were also treated with NaCl, 10 mg/kg ginseng (E10), or 30 mg/kg (E30). Decreases in CR immunoreactivity (IR) along with loss of CA1 and CA3 interneurons and infragranular cells were observed in the ENaCl group while such losses were not observed in the E10 and E30 groups. CR IR significantly increased in the RG-treated group compared to control and EMF-exposed groups treated with NaCl. The study demonstrates that RG extract can serve as a radioprotective agent that maintains $Ca^{2+}$ homeostasis and prevents neuronal loss in the brain hippocampal region caused by RF exposure.

• The KIPS Transactions:PartB
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• v.16B no.4
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• pp.309-318
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• 2009

The researches on the system that automatically records and retrieves one's everyday life is relatively actively worked recently. These systems, called personal memex or life log, usually entail dedicated devices such as SenseCam in MyLifeBits project. This research paid attention to the digital devices such as mobile phones, credit cards, and digital camera that people use everyday. The system enables a person to store everyday life systematically that are saved in the devices or the deviced-related web pages (e.g., phone records in the cellular phone company) and to refer this quickly later. The data collection agent in the proposed system, called MyMemex, collects the personal life log "web data" using the web services that the web sites provide and stores the web data into the server. The "file data" stored in the off-line digital devices are also loaded into the server. Each of the file data or web data is viewed as a memex event that can be described by 4W1H form. The different types of data in different services are transformed into the memex event data in 4W1H form. The memex event ontology is used in this transform. Users can sign in to the web server of this service to view their life logs in the chronological manner. Users can also search the life logs using keywords. Moreover, the life logs can be viewed as a diary or story style by converting the memex events to sentences. The related memex events are grouped to be displayed as an "episode" by a heuristic identification method. A result with high accuracy has been obtained by the experiment for the episode identification using the real life log data of one of the authors.

• Herbal Formula Science
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• v.21 no.2
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• pp.133-143
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• 2013

Objectives : We carry out the simultaneous quantification for quality control of four components in Bangpungtongseong-san (BPTSS) sample. In addition, we assessed the antioxidant effects of BPTSS sample. Methods : The used column for separation and analysis of four compounds was Luna C18 column and column oven temperature was maintained at $40^{\circ}C$. The mobile phase for simultaneous determination consisted of two solvent systems, 1.0% acetic acid in water and 1.0% acetic acid in acetonitrile. High performance liquid chromatography-photodiode array (HPLC-PDA) method for analysis was performed at a flow rate of 1.0 mL/min with PDA detection at 254 and 280 nm. The injection volume was 10 ${\mu}L$. The antioxidant activities of BPTSS were evaluated by measuring free radical scavenging activities on 2,2'-Azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) and 1-1-diphenyl-2-picrylhydrazyl (DPPH). The inhibitory effects on low-density lipoprotein (LDL) oxidation were evaluated by the formation of thiobarbituric acid relative substances (TBARS) and relative electrophoretic mobility (REM). Results : Calibration curves were acquired with $r^2{\geq}0.9999$. The values of limit of detection (LOD) and quantification (LOQ) were 0.06-0.29 ${\mu}g/mL$ and 0.20-0.98 ${\mu}g/mL$, respectively. The amounts of geniposide, liquiritin, baicalin, and glycyrrhizin in BPTSS were 5.06, 7.33, 27.56, and 7.81 mg/g, respectively. The BPTSS showed the radical scavenging activity in a dose-dependent manner. The concentration required for 50% reduction (RC50) against ABTS and DPPH radicals were 72.51 ${\mu}g/mL$ and 128.49 ${\mu}g/mL$. Furthermore, GMGHT reduced the oxidation properties of LDL induced by CuSO4. Conclusions : The established HPLC-PDA method will be helpful to improve quality control of BPTSS. In addition, BPTSS has potentials as therapeutic agent on anti-atherosclerosis.