• 제목/요약/키워드: miR125a

검색결과 50건 처리시간 0.023초

Cost and Benefits of R&D Tax Concession Program in the Australian Government

  • Moon Yong-Eun;Yoon Joseph
    • 한국정보시스템학회지:정보시스템연구
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    • 제13권1호
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    • pp.135-159
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    • 2004
  • In industrialised countries, innovation is a key source of economic growth. Rrsearch is a key driver of technological innovation and involves the process of systematic investigation and/or experimentation to discover new knowledge. The Governments'industry innovation policy supports a business focus on Research and Development (R&D) through a range of programs in order to achieve these aims. The Innovation Statement (DISR 2000, 20010, launched by the Australian Prime MinisterJanuary 2001, commits an additional ${\$}$3 billion over five years to encourage and support innovation. The Australian Government aims toworld competitive firms and strong research capability in industry to strengthen Australia's international competitiveness and increase national prosperity. It develops policies and programs to enhance investment in innovation. The Australian Government has established a number of R&D funding support programs aimed at increasing the level of R&D in Australia. The backbone of these programs is the tax concession program, which is made up of the 125 per cent R&D tax concession, the 175 per cent premium tax concession and the tax offset. Over 4000 businesses take advantage of the tax concession scheme, which costs the government around ${\$}$400mi11ion a year. This cost is expected to rise to over hall a billion by 2005-06 (commonwealth or Australia, 2003). Ensuring these resources are invested where they provide significant national economic benefits is a major policy issue. In this sense, this paper looks at the appropriateness, effectiveness and efficiency of the R&D tax concession with costs and benefits analysis.

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Optimization of Antibacterial Activity by Gold-Thread (Coptidis Rhizoma Franch) Against Streptococcus mutans Using Evolutionary Operation-Factorial Design Technique

  • Choi, Ung-Kyu;Kim, Mi-Hyang;Lee, Nan-Hee
    • Journal of Microbiology and Biotechnology
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    • 제17권11호
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    • pp.1880-1884
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    • 2007
  • This study was conducted to find the optimum extraction condition of Gold-Thread for antibacterial activity against Streptococcus mutans using The evolutionary operation-factorial design technique. Higher antibacterial activity was achieved in a higher extraction temperature ($R^2=-0.79$) and in a longer extraction time ($R^2=-0.71$). Antibacterial activity was not affected by differentiation of the ethanol concentration in the extraction solvent ($R^2=-0.12$). The maximum antibacterial activity of clove against S. mutans determined by the EVOP-factorial technique was obtained at $80^{\circ}C$ extraction temperature, 26 h extraction time, and 50% ethanol concentration. The population of S. mutans decreased from 6.110 logCFU/ml in the initial set to 4.125 logCFU/ml in the third set.

Preparations of Chemical Cellulose from Ascidian Tunic and Effect of Spinning Conditions on the Properties of New Regenerated Cellulose Fiber

  • Koo, Won-Mi;You, Sang-Hoon;Lee, Dong-Jin;Kim, Eun-Young;Kim, Han-Do
    • 한국섬유공학회:학술대회논문집
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    • 한국섬유공학회 2000년도 봄 한국섬유공학회 학술발표회 논문집(Proceedings of the Korean Textile Conference)
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    • pp.125-128
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    • 2000
  • Chemical cellulose from an ascidian tunic is isolated by extraction, digestion and bleaching steps. The content of $\alpha$-cellulose was above 98 wt%, and it's DPw was about 918. A new regenerated cellulose fiber from the chemical cellulose obtained in this study was made using NMMO/water(87/13 wt%) as a solvent by dry jet-wet spinning. The effects of spinning speed and cellulose content of spinning dope on the properties were investigated.

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Dietary Iron Intake and Body Iron Status of Myocardial Infarction Patients in Chunan Area

  • Kim, Hee-Seon
    • Journal of Community Nutrition
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    • 제1권2호
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    • pp.140-147
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    • 1999
  • It has been known for some time that elevated body iron could be a risk factor for coronary heart disease. The present study was conducted to determine body iron status and dietary iron intake of patients with myocardial infarction(MI). Seventy five patients from the Chunam area with their first MI history within he past 2 months were recruited. The serum iron concentration, total iron binding capacity(TIBC) and percent transferrin saturation(TS) were selected as indicators of body iron status. Twenty four hour recall was conducted by trained interviewers to asses the dietary intake. Most women (91.3%) showed waist to hip ratio(W/H) greater than 0.85 while 17.3% of men were assessed to have a tendency of abdominal obesity(W/H>0.95). The average BMI of women was 25.80 and that of men was 23.98. The average diet intake of participants was below the recommended dietary allowances (RDA) for most nutrients. He average dietary iron intake was 10.03 mg/day for all subjects while women's iron intake was significantly lower than men's. However, a great proportion of participants (77%) showed a tendency to have normal iron status. About 9% of the participants were assessed as iron deficient and 14% had an iron overload. The mean serum iron concentration was 125 g/dl ranging from 13.3 to 280.6 g/dl. Iron intake from animal sources were significantly associated with body iron status (r=0.257, p=0.026) when TIBC was used as an iron status indicator. When iron status was assessed with TS, it was directly associated with iron intake from animal sources(r=0.278, p=0.05) for he subjects in the normal iron status group. He results of the present study showed that the nutrient intake of Mi patients in Chunan was not quite adequate while iron status was mostly in the normal range. Further studies are needed to investigated whether there is a possible difference in iron metabolism of the MI patients.

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선편광된 10 GHz 선폭의 1 kW급 20/400-㎛ 이터븀 첨가 광섬유 레이저 (Linearly Polarized 1-kW 20/400-㎛ Yb-doped Fiber Laser with 10-GHz Linewidth)

  • 정예지;정민완;이강인;김태우;김재인;이용수;조준용
    • 한국광학회지
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    • 제32권3호
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    • pp.120-125
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    • 2021
  • 본 연구에서는 다파장 빔결합을 위한 master oscillator power amplifier (MOPA) 구조의 선편광 고출력 이터븀 첨가 광섬유 레이저를 개발하였다. 유도 브릴루앙 산란(stimulated Brillouin scattering, SBS)을 억제하기 위하여 pseudo-random binary sequence (PRBS) 신호로 위상 변조 및 비트길이를 최적화한 선폭 약 10 GHz의 시드 레이저를 구현하였으며, 이를 이용하여 3단 증폭을 하였다. 주 증폭단에서는 모드 불안정성 현상(mode instability, MI)의 문턱값을 높이기 위하여 코어 및 클래딩의 직경이 각각 20 ㎛, 40 ㎛인 편광유지(polarization maintaining, PM) 이터븀 첨가 광섬유를 이용하고 지름이 약 9-12 cm인 나선형 홈에 적용하였다. 그 결과, 입사된 여기광 대비 기울기 효율이 83.7%인 1.004 kW의 레이저 출력을 얻었다. 또한, 빔품질(M2)과 편광소광율(polarization extinction ratio, PER)은 각각 1.12와 21.5 dB로 측정되었다. 더욱이, 역방향 스펙트럼의 레일리 신호와 SBS 신호의 첨두 세기 비율은 2.36 dB로 관측되어, SBS가 완화된 레이저 구현을 확인하였다. 또한 증폭 출력에 따라 기울기 효율 및 빔품질의 저하가 없어 모드불안정이 발생하지 않음을 확인하였다.

Headspace GC-MS Analysis of Spring Blossom Fragrance at Chungnam National University Daedeok Campus

  • Choi, Yeonwoo;Lee, Sanghyun;Kim, Young-Mi;Nguyen, Huu-Quang;Kim, Jeongkwon;Lee, Jaebeom
    • Mass Spectrometry Letters
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    • 제13권4호
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    • pp.125-132
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    • 2022
  • There are many types of spring blossoms on the Daedeok campus of Chungnam National University (CNU) at the area of 1,600,000 square meters. As an assignment for the class of Analytical Chemistry I for second-year undergraduate students, 2021, flower petals collected from various floral groups (Korean azalea, Korean forsythia, Dilatata lilac, Lilytree, Lily magnolia, and Prunus yedoensis) were analyzed using headspace extraction coupled to gas chromatography-mass spectrometry (HS-GC-MS) to study the aromatic profiles and fragrance compounds of each sample group. Various types of compounds associated with the aroma profiles were detected, including saturated alcohols and aldehydes (ethanol, 1-hexanol, and nonanal), terpenes (limonene, pinene, and ocimene), and aromatic compounds (benzyl alcohol, benzaldehyde). The different contribution of these compounds for each floral type was visualized using statistical tools and classification models based on principal component analysis with high reliability (R2 = 0.824, Q2 = 0.616). These results showed that HS-GC-MS with statistical analysis is a powerful method to characterize the volatile aromatic profile of biological specimens.

한국 남부 지역별 돼지 장내 미생물생태 비교분석 (Differences in swine gut microbiota in southern region of Republic of Korea)

  • 김정만;;;운노타쯔야
    • 미생물학회지
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    • 제51권1호
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    • pp.81-85
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    • 2015
  • 성장촉진제로 항생제 사용이 금지가 된 이후, 가축들의 사망률이 증가되어 항생제 대체제를 개발해야 하는 것이 시급하다. 그러한 대체제 개발에 새로운 접근 중 하나는 숙주의 신체적 기능에 영향을 준다고 알려진 장내미생물생태를 조절하는 것이다. 하지만 가축의 장내미생물에 대한 이해가 인간과 비교하여 볼 때 많이 부족한 실정이다. 본 연구에서는 돼지장내미생물생태가 지역적 차이가 있음에 대한 기본적인 정보를 제공한다. 돼지 분변샘플은 제주(n=40), 광주(n=28), 해남(n=30) 농가로부터 채취하였으며, MiSeq을 이용하여 16S rRNA V4 지역을 시퀀싱하였다. 또한 Mothur 파이프라인을 이용하여 MiSeq으로부터 얻은 데이터를 처리하였다. 총 5,642,125 reads를 얻었으며, 에러시퀀스들을 제거한 후 최종적으로 3,868,143 reads가 남았다. Phylum 수준의 taxonomic composition 분석에서는 제주 돼지들이 Firmicutes를 가장 많이 포함하고 있었으며, Operational Taxonomic Units 분포분석에서 또한 지역적 차이에 따라 돼지장내미생물생태가 다르다는 것을 확인하였다. Non-metric multidimensional scaling과 Phyla의 풍부함 사이의 상관관계분석에서는 Actinobacter, Verrucomicrobia, Firmicutes, Fibrobacteres이 세 개의 지역에 있는 돼지들의 장내미생물생태 차이를 나타나게 하는 장내 미생물 요소라는 것을 확인하였다. 그러한 가축의 장내미생물생태는 농장에서 사용하는 사료와 사양관리에 의해 많은 영향을 미치는 것으로 생각된다. 본 연구결과는 돼지장내미생물생태가 지역적으로 많은 차이가 있다는 것을 나타내며, 추후에 가축의 장내미생물생태에 관한 연구는 지역적 차이가 있다는 것을 고려하여 설계해야 될 것이다.

일 지역사회 산업장 근로자의 음주형태, 직무스트레스 및 여가만족도가 건강증진행위에 미치는 영향 (The Effects of Drinking Patterns, Job Stress, and Leisure Satisfaction on Health Promotion Behaviors of Industrial Workers)

  • 장경오;박미화
    • 한국산학기술학회논문지
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    • 제22권3호
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    • pp.499-510
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    • 2021
  • 본 연구는 산업장 근로자의 음주형태, 직무스트레스 및 여가만족도가 건강증진 행위에 미치는 영향을 파악하기 위한 서술적 조사연구이다. 조사대상은 U광역시에 소재한 3개의 병원에서 건강검진을 받는 산업장 근로자 207명을 대상으로 시행하였으며, 구조화된 설문지를 통해 2019년 11월 1일부터 2019년 11월 30일까지 자료를 수집하였다. 자료 분석은 IBM SPSS 24.0 통계프로그램으로 분석하였다. 그 결과, 대상자의 음주빈도는 주 2~3회 음주가 36.3%로 가장 많았고, 술을 마시는 동기는 친목 도모가 54.6%이었다. 직무스트레스의 평균 점수는 62.46±5.59점, 여가만족도는 30.29±6.39점, 건강증진행위는 125.64±8.77점으로 중간보다 다소 높았다. 연구대상자의 건강증진행위는 연령(r=-.162, p<.020)과 음의 상관관계, 결혼상태(r=.149, p<.032), 직무스트레스(r=.227, p<.001) 여가만족도(r=.542, p<.001)는 유의한 양의 상관관계가 있는 것으로 나타났다. 연구대상자의 건강증진행위에 영향을 미치는 요인을 다중회귀로 분석한 결과, 음주형태, 직무스트레스 및 여가 만족도가 건강증진행위에 영향을 미치는 요인으로 설명력은 29.7%이었다. 본 연구를 기반으로 산업장 근로자들이 음주가 아닌 여가활동을 통한 친목 도모와 건강증진을 위한 다양한 여가활동으로 직무스트레스에서 벗어날 수 있도록 지속적인 지원이 필요하며, 이를 위한 프로그램운영과 시스템 지원으로 산업장 근로자들이 건강한 생활양식과 건강증진 활동을 통한 삶의 질 개선을 기대한다.

여대생의 월경전 증후군과 성역할과의 관계 (The Relationship between Premenstrual Syndrome and Sex Role of College Students)

  • 신미아;정미현
    • 지역사회간호학회지
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    • 제17권1호
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    • pp.125-133
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    • 2006
  • Purpose: This study was performed to identify the relationship between PMS and sex role. Method: Data were collected from 417 female college students in Seoul and Gyeonggi-do area during the period from the 6th of September to the 15th of October in 2004. Collected data were analyzed using SPSS WIN 11.0. Result: The results of this study were as follows: 1) Perceived subjective symptoms were clustered endogenous depressive feature ($2.76{\pm}.97$), anxiety ($2.76{\pm}1.09$), and impulsivity ($2.72{\pm}1.02$). 2) PMS was significantly different according to the general characteristics of menarche age (F=5.910, p=.003), pain (F=7.886. p=.000) and family history (F=5.366, p=.005), masculinity was significantly different according to menarche age (F=3.174, p=.043), and femininity was significantly different according to menarche age (F=3.742, p=.025) and pain (F=3.256. p=.040). 3) Femininity and PMS were in a positive correlation with each other (r=.623. p=.000). Conclusion: This results showed that there is a significant correlation between PMS and sex role. For future research, it is recommended to identify major factors affecting PMS and the relationships between them and various subjects.

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都市 超高層 住居建築의 室內空氣環境의 評價에 관한 硏究 (A Study on the Evaluation of Indoor Air Environment in Super High-Rise Dwelling House)

  • 박미진
    • 한국안전학회지
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    • 제17권4호
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    • pp.119-125
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    • 2002
  • The concept of dwelling space is tend to be changed not only to have reasonable mobility but also to have high quality of indoor air with psychologicaa satisfaction and comfortable. Moreover, recent constructed buildings have a big problem because of exhausted pollution gas and particles from building materials. More serious problem occurs from its high air tightness reducing the ventilation for saving the energy and superior adiabatic insulators to have high heat efficiency. Indoor air quality in super high-rise dwelling house was investigated by measuring pollutants such as $CO_2,=;CO,\;MO_2,\;R_n,\;TSP,\;PM_{10}$, HCHO, Offensive ordor. Subjective evaluation of residential environment is processed for the inhabitants who live in research space by testing environmental load in accordance with environment morphology, exterior environmental factor and post occupancy correlation and influence of attention.