• The Journal of the Korea Contents Association
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• v.19 no.3
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• pp.375-384
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• 2019

The purpose of this study is to investigate the relationship among stress, smartphone addiction, and depression of university students and whether depression is mediators in the relationship between stress and smartphone addiction. For this purpose, data were collected from May 1st to 31, 2017 from 400 university students, and analyzed 381 valid ones. Frequency analysis, reliability analysis, correlation analysis and regression analysis were used as analysis methods; and the Soble test was conducted in addition to verification of mediator effect according to procedures of Baron & Kenny(1986) for verification of mediator effect. The results of this study are as follows. First, stress of the subjects was positively correlated with depression(employment stress r=.353, economic stress r=.193, heterosexual relationship stress r=.138) and smartphone addiction(employment stress r=.262, economic stress r=.178, heterosexual relationship stress r=.190). Second, depression was a statistically significant partial mediator between employment-stress and smartphone addiction(Z=2.7151, p<.001). Based on the results of this study, I proposed education/counseling programs that can relieve employment-stress and depression.

• Journal of Microbiology and Biotechnology
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• v.21 no.2
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• pp.170-175
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• 2011

This study was carried out for the molecular level identification of recombinant protein vaccine efficacy, by oral feeding against white spot syndrome virus infection, with the comparison of viral mRNA transcriptional levels in shrimp cells. For the determination of WSSV dilution ratio for the vaccination experiment by oral feeding, in vivo virus titration was carried out using different virus dilutions of virus stock ($1{\times}10^2$, $2{\times}10^2$, and $1{\times}10^3$). Among the dilution ratios, $2{\times}10^2$ diluted WSSV stock was chosen as the optimal condition because this dilution showed 90% mortality at 10 days after virus injection. Recombinant viral proteins, rVP19 and rVP28, produced as protein vaccines were delivered in shrimps by oral feeding. The cumulative mortalities of the shrimps vaccinated with rVP19 and rVP28 at 21 days after the challenge with WSSV were 66.7% and 41.7%, respectively. This indicates that rVP28 showed a better protective effect against WSSV in shrimp than rVP19. Through the comparison of mRNA transcriptional levels of viral genes from collected shrimp organ samples, it was confirmed that viral gene transcriptions of vaccinated shrimps were delayed for 4~10 days compared with those of unvaccinated shrimps. Protection from WSSV infection in shrimp by the vaccination with recombinant viral proteins could be accomplished by the prevention of entry of WSSV due to the shrimp immune system activated by recombinant protein vaccines.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2329-2334
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• 2012

Introduction: Many studies have reported that microRNA-21 (miR-21) mihght predict the survival outcome in non-small cell lung cancers (NSCLCs) but the opposite opinion has also been expressed. The aim of this study was to summarize the evidence for a prognostic role of miR-21. Materials and Methods: All the eligible studies was searched by Medline and EMBASE and patients' clinical characteristics and survival outcome were extracted. Then a meta-analysis was performed to clarify the prognostic role of the miR-21 expression in different subgroups. Results: A total of 8 eligible articles were yielded covering survival outcomes or clinical characteristics. The combined hazard ratio (HR) and 95% confidence interval (95% CI) for overall survival (OS) was 2.19 [0.76, 6.30], while the combined HR (95% CI) of Asian group for OS had a significant result, 5.49 [2.46, 12.27]. The combined HR (95% CI) for recurrence free survival or disease free survival (RFS/DFS) was 2.31 [1.52, 3.49]. Odds ratios (ORs) showed that the miR-21 expression was associated with lymph node status and histological type. Conclusion: miR-21 expression could predict the prognostic outcome of NSCLC in Asians, despite some deficiencies in the study data.

• Women's Health Nursing
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• v.29 no.4
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• pp.274-290
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• 2023

Purpose: This study investigated the effects of prenatal education characteristics, pandemic-related pregnancy stress, and health behaviors during pregnancy on prenatal depression in pregnant women during the coronavirus disease 2019 (COVID-19) pandemic. Methods: The participants were 180 pregnant Korean women, recruited from internet communities for pregnancy preparation, childbirth, and childcare, from July 5 to 15, 2022. The collected data were analyzed using the t-test, analysis of variance, the Mann-Whitney U-test, the Kruskal-Wallis test, and multiple regression analysis. Results: The scores for pandemic-related pregnancy stress (24.50±6.37) and health behaviors during pregnancy (67.07±9.20) were high. Nearly half of the participants (n=89, 49.4%) presented with prenatal depression, with scores of 10 or greater. Prenatal depression had a positive correlation with gestational age (r=.18, p=.019) and pandemic-related pregnancy stress (r=.27, p<.001), and a negative correlation with health behaviors during pregnancy (r=-.42, p<.001). The factors associated with prenatal depression were pandemic-related pregnancy stress (t=4.70, p<.001), marital satisfaction (dissatisfied) (t=3.66, p<.001), pregnancy healthcare practice behaviors (t=-3.31, p=.001), family type (weekend couple) (t=2.84, p=.005), and gestational age (t=2.32, p=.022). The explanatory power of these variables was 38.2%. Conclusion: Since participants had a high level of prenatal depression during the pandemic, and infectious diseases such as COVID-19 may recur, strategies should be developed to improve pregnant women's mental health with consideration of the unique variables that are relevant in a pandemic. It is also necessary to develop efficient online prenatal education programs that can be implemented even in special circumstances such as social distancing, and to evaluate their effectiveness.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.12
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• pp.1695-1704
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• 2014

Maternal malnutrition during pregnancy may give rise to female offspring with disrupted ovary functions in adult age. Neonatal ovary development predisposes adult ovary function, yet the effect of maternal nutrition on the neonatal ovary has not been described. Therefore, here we show the impact of maternal protein restriction on the expression of folliculogenic and steroidogenic genes, their regulatory microRNAs and promoter DNA methylation in the ovary of neonatal piglets. Sows were fed either standard-protein (SP, 15% crude protein) or low-protein (LP, 7.5% crude protein) diets throughout gestation. Female piglets born to LP sows showed significantly decreased ovary weight relative to body weight (p<0.05) at birth, which was accompanied with an increased serum estradiol level (p<0.05). The LP piglets demonstrated higher ratio of bcl-2 associated X protein/B cell lymphoma/leukemia-2 mRNA (p<0.01), which was associated with up-regulated mRNA expression of bone morphogenic protein 4 (BMP4) (p<0.05) and proliferating cell nuclear antigen (PCNA) (p<0.05). The steroidogenic gene, cytochrome P450 aromatase (CYP19A1) was significantly down-regulated (p<0.05) in LP piglets. The alterations in ovarian gene expression were associated with a significant down-regulation of follicle-stimulating hormone receptor mRNA expression (p<0.05) in LP piglets. Moreover, three microRNAs, including miR-423-5p targeting both CYP19A1 and PCNA, miR-378 targeting CYP19A1 and miR-210 targeting BMP4, were significantly down-regulated (p<0.05) in the ovary of LP piglets. These results suggest that microRNAs are involved in mediating the effect of maternal protein restriction on ovarian function through regulating the expression of folliculogenic and steroidogenic genes in newborn piglets.

• Journal of Digital Convergence
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• v.19 no.5
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• pp.333-342
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• 2021

The purpose of this study was to examine to identify factors affecting wellness of fire officials. This study collected questionnaire data from 219 fire officials working in Gyeongsangnam-do. Data were analyzed using descriptive statistics, Pearson's correlation, Sobel test and multiple regression analysis with IBM SPSS statistics 24.0 program. Wellness of fire officials was correlated with job stress(r=.-49, p<.001) and positive psychological capital(r=.70, p<.001). In addition, job stress showed a significant negative correlation with positive psychological capital (r=-.56, p<.001). As a result of analyzing the mediating effect of positive psychological capital on the relationship between job stress and wellness of fire officials, positive psychological capital showed a significant mediating effect. Based on the finding, it is necessary to develop an intervention program that strengthens positive psychological capital in order to improve the wellness of fire officials and reduce job stress.

• The Journal of Korean Academic Society of Nursing Education
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• v.19 no.2
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• pp.228-240
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• 2013

Purpose: This study was to evaluate the applicability of an emergent care management simulation practicum which is for enhancing nursing students' emergent care management competency based on the Nursing Education Simulation Model. Methods: One group pre-post experimental design was conducted for evaluation of the applicability of the simulation practicum. A convenient sample of 60 senior nursing students was participated. The simulation practicum was provided for 26 hours per student at the end of the first semester of senior year. Educational practices in simulation scale, simulation design scale and learning outcomes were measured. Higher positive correlations between variables represent applicability. Descriptive analysis, paired t-test and Pearson correlation coefficient were used for data analyses. Results: Among contractual components of nursing education simulation model, educational practices in simulation and simulation design (r=.80, p<.010), learning outcomes (r=.71-.28, p<.050), simulation design and learning outcomes (r=.72-.30, p<.050) were significantly correlated. Critical thinking (t=-3.63, p<.050) and problem solving competence (t=-2.55, p<.050) were significantly increased by this simulation practicum. It represents the applicability of an emergent care management simulation practicum. Conclusion: This emergent care management simulation practicum was appropriate to enhance the nursing students' emergent care management coping competency.

• Journal of Korean Biological Nursing Science
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• v.19 no.4
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• pp.215-226
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• 2017

Purpose: The purpose of this study was to investigate the effects of general, health, and alcohol-related characteristics on blood pressure and stress according to the Alcohol Use Disorders Identification Test (AUDIT). Methods: This was a descriptive study. From participants in the 2013 Korea National Health and Nutrition Examination Survey, 319 participants who responded to the survey when they were attending college or university were selected. Data were analyzed using the SPSS Win 23.0 program for composite sample data reflecting the composite design elements of stratification, colonization, and weighting. Results: Mean age of onset of alcohol drinking was $17.91{\pm}0.16$ years, the average AUDIT score was $7.56{\pm}0.41$, and 25 (9.1%) participants fell into the high-risk drinking group. In the high-risk AUDIT group, systolic blood pressure was influenced by age, gender, institution, health status, body mass index, and suicidal ideation, and the explanatory power of the model ($R^2$) was 75.0%. For diastolic blood pressure, institution and health status were the influential factors, and $R^2$ was 66.2%. Predictors of stress were health status, depression, and the age of onset of drinking, and $R^2$ was 57.2%. Conclusion: It was confirmed that the explanatory power of the variables in models of systolic and diastolic blood pressure and stress is greater in those with higher scores on AUDIT.

• Journal of Korean Clinical Nursing Research
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• v.28 no.3
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• pp.299-307
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• 2022

Purpose: The purpose of this study was to understand the effects of infection control fatigue and social support on burnout among nurses during the Coronavirus Disease 2019 (COVID-19) pandemic. Methods: This study is a descriptive survey study designed to confirm the effects of nurses' infection control fatigue and social support on burnout among nurses during the COVID-19 pandemic. The collected data were analyzed using frequency, percentage, mean, standard devia analyzed using frequency, percentage, mean, standard deviation, independent t-test, One-way ANOVA, Scheffe test, Pearson's correlation coefficient, and stepwise multiple regression analysis using SPSS Statistics 26.0. Results: An analysis of the correlations between fatigue from infection control, social support, and burnout showed a positive correlation between burnout and fatigue from infection control (r=.39, p<.001), and a negative correlation between burnout and social support (r=-.29, p<.001). Conflict and lack of support due to uncertain circumstances (β=.51, p<.001), support from supervisor's (β=-.22, p<.001), and experience of infection management education during the previous 1year (β=-.15, p=.007) were identified as the factors that influenced burnout among nurses, and explained 39.0% of the variance in burnout. Conclusion: The results of this study demonstrate that fatigue from infection control and social support influence burnout levels among nurses, which suggests the need to establish a new kind of work culture. Additionally, the findings call for the development and implementation of interventional programs that can reduce fatigue from infection control and increase social support for nurses.

• Journal of the Korean Society of Radiology
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• v.15 no.4
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• pp.519-524
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• 2021

As the COVID-19 situation continued to spread to the local community along with the spread due to influx, each university had to conduct all online classes and partially online classes. The purpose of this study was to investigate the satisfaction of learners with the content and lecture contents by paying attention to online non-face-to-face classes according to the change of the class environment in the Corona 19 situation. Satisfaction survey on online non-face-to-face class major subjects was analyzed using questionnaires from June 1 to June 11, 2021, targeting 2nd and 3rd year students in the Department of Radiology at S University in Daegu. As a result of the study, satisfaction with content and class content was found to be an average of 3.78 ± 0.75 points, and learning satisfaction was found to be an average of 3.00 ± 1.14 points. In addition, when taking online non-face-to-face classes, the correlation between students' class attitude and content and class content satisfaction was the highest (r=0.555, p<0.01), and it was found that there was also a correlation between content and class content satisfaction and learning satisfaction. (r=0.331, p<0.01). I think that satisfaction with non-face-to-face online classes can be improved if the quality of content is improved during non-face-to-face online major classes as well as more active interactions between students and professors.