• Journal of the Korean Data and Information Science Society
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• 제24권4호
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• pp.867-876
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• 2013

대사증후군은 심혈관질환의 발생을 증가시키는 주요 요인으로 알려져 왔다. 특히 만성적인 대사장애로 여러 질병이 한 개인에게서 복합되어 나타나는 대사증후군의 경우 우리나라에서도 유병률이 점차 증가하는 추세이다. 이에 본 연구는 다중인자 차원 축소 방법을 이용하여 대사증후군의 위험도를 확인하고 여러 대사증후군 진단 조합 중에서 가장 위험한 조합을 제시하는 데 목적을 둔다. 자료는 질병관리본부에서 실시한 제 5기 국민건강영양조사 1차년도 (2010년)자료를 이용하여 성인 중에서 분석방법에 적용이 가능한 3,990명을 대상자로 결정하였다. 다중인자 차원 축소 방법을 적용시킨 결과 대사증후군에 가장 위험한 단일 요인은 복부비만이었고, 복부비만을 포함한 대사증후군 진단 조합은 복부비만과 고지혈증, 고혈압이 가장 위험한 것으로 나타났다. 이것은 대사증후군의 새로운 진단 결과이다. 특히, 남성의 경우는 복부비만, 저 HDL-콜레스테롤혈증, 고혈압이 가장 위험한 조합으로 확인되었고 체질량 지수가 $25kg/m^2$이상인 사람에게서는 복부비만, 고지혈증, 고혈당의 조합이 가장 위험한 대사증후군 조합이었다.

• 사상체질의학회지
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• 제34권4호
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• pp.27-37
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• 2022

Objectives The purpose of this study is to propose a method to more specifically identify Sasang constitutional risk factors of metabolic syndromes by adjusting the cut-off value of Korea Sasang Constitutional Diagnostic Questionnaire (KS-15). Methods Data of 1997 participants in Korean medicine Daejeon Citizen Cohort study (KDCC) were analyzed. Metabolic syndrome was defined according to the NCEP-ATP III, lifestyle information, and hematologic information including KS-15 and demographic characteristics were used as covariates. Results The 179 subjects with metabolic syndrome accounted for 9.0% of the total. As a result of determining the Sasang constitution for the KS-15 response based on the cut-off values (approximate 0.33), 0.5, and 0.6 of the constitutional score, when performed at the 0.6 cut-off model, the odds ratio of TE was 2.46 which showed a statistically significantly higher risk than the borderline group. For the accuracy of the model and the Area under the curve (AUC), the model accuracy based on the original cut-off of the KS-15 was 0.902 and AUC was 0.737. The accuracy of the model with cut-off of 0.5 and with of 0.6 were 0.904 and 0.902, respectively, and the AUCs were 0.687 and 0.741, respectively. Conclusion In this study, we confirmed that it is effective to increase the cut-off value of KS-15 to 0.6 in the metabolic syndrome risk model. It is expected that this could increase the accuracy of identifying high-risk groups for metabolic syndrome.

• 한국식품영양학회지
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• 제31권3호
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• pp.425-434
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• 2018

Metabolic syndrome is a risk factor for cardiovascular and type 2 diabetes. This study was conducted to examine the relevance between nutrition intake, meal quality, and high-sensitivity C-reactive protein in Koreans with metabolic syndrome. The 2,536 subjects, aged 19~64, who participated in 2015 National Nutrition Survey were included in this study. The 24-hour recall method was employed to analyze nutrition intake and dietary quality. Subjects were grouped into either the non-metabolic syndrome group (n=1,938) or the metabolic syndrome group (n=598). Total males and females were divided into 3 groups according to the high-sensitivity C-reactive protein (hs-CRP) level to study its relationship to metabolic syndrome and its components, including odds ratio (OR) and confidence interval (CI). Results showed the homeostasis model assessment of insulin resistance (HOMA-IR) value was higher in the metabolic syndrome group (3.37) than non-metabolic syndrome group (1.57) (p<0.001). In the Index of Nutrition Quality, males in the non-metabolic syndrome group showed higher niacin (p<0.05) than males in metabolic syndrome group. Females in the non-metabolic syndrome group had higher vitamin $B_1$ (p<0.01), vitamin $B_2$ (p<0.001), niacin (p<0.05), calcium (p<0.001), and phosphate (p<0.01). Female in the high hs-CRP group showed high OR in blood glucose component (OR 2.488, 95% CI: 1.269~4.879) and metabolic syndrome risk (OR 2.856, 95% CI: 1.292~6.314). Females in the middle hs-CRP group had high triglycerides component (OR 2.956, 95% CI: 1.920~4.551), compared to the low hs-CRP group. The study showed females with higher hs-CRP had a higher risk of metabolic syndrome.

• 동서간호학연구지
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• 제30권1호
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• pp.60-69
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• 2024

Purpose: This study was conducted to determine the impact of premature menopause (PM) on metabolic syndrome and its components to determine its contribution to the health of Korean women undergoing natural menopause. Methods: This study used data from the 4^th to 8^th National Health and Nutrition Examination Survey (2007~2021). A total of 11,989 women aged 30 to 65 who responded to questions about their current menstrual status, natural menopause status and its age. Complex sample multivariate Cox proportional hazards regression analysis was used. Results: Compared with women with late menopause, women with PM had a 1.34 times higher risk of developing metabolic syndrome. Excluding the risk of high blood pressure, women with PM had a significantly higher risks of increased waist circumference, decreased high-density lipoprotein, increased risk of high triglycerides, and increased fasting blood glucose. Conclusions: The results of this study provided data that can be applied to policies or interventions to prevent or manage metabolic syndrome in women with PM in Korea.

• 한국식품영양학회지
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• 제28권6호
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• pp.988-994
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• 2015

Menopausal status and hormonal changes are important factors related to the prevalence of metabolic syndrome in women. Nutrient intake is also a risk factor for metabolic syndrome. Although, postmenopausal status and hormonal changes result in a 60% increased risk for metabolic syndrome, there has been no method to elucidate the effects of nutrient intake on metabolic syndrome following menopause. This study was conducted to evaluate the effects of nutrient intake by menopausal women on the prevalence of metabolic syndrome. All data were obtained from the Korean National Health and Nutrition Examination Survey 2007-2009. Menopausal women showed a 1.8-fold increase in the prevalence of metabolic syndrome. Metabolic syndrome group showed significantly lower values in calcium, iron, vitamin A, carotin, retinol and riboflavin intake than those of normal group in premenopausal women. In postmenopausal women, there are significant differences in crude fiber, calcium, iron, potassium, riboflavin and niacin. Indeed, different patterns of nutrient intake were observed by menopausal status and metabolic syndrome. As menopause cannot be controlled, a diet with adequate nutrient intake may be useful to control the rapid increase in the prevalence of metabolic syndrome due to menopause.

• 대한지역사회영양학회지
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• 제29권3호
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• pp.173-188
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• 2024

Objectives: The study aim was to analyze the regional differences in dietary protein intake and protein sources of Korean older adults and their association with metabolic syndrome. Methods: Study participants were 1,721 older adults aged 65 and over who participated in 2016-2019 Korea National Health and Nutrition Examination Survey. Using 24-hour recall dietary intake data, protein intake and their food sources were examined. The association between protein intake and metabolic syndrome, obesity, and abdominal obesity were analyzed by multiple logistic regression. Results: Total protein and animal protein intakes were higher in urban area (60.0 g, 24.4 g, respectively) than in rural area (54.6 g, 19.6 g, respectively). With increase of protein intake level, animal to total protein proportion was increased in both areas. Total protein and plant protein intake was negatively associated with the risk of obesity, abdominal obesity in both areas. Animal protein intake was negatively associated with the risk of obesity in both areas, and with abdominal obesity only in urban area. In urban area, plant protein intake was also negatively associated with the risks of metabolic syndrome, elevated triglyceride, and reduced high density lipoprotein-cholesterol. In urban area, the risk of metabolic syndrome was decreased when their protein intake was more than 0.91 g/kg and was lowest when their protein intake was more than 1.5 g/kg (P for trend < 0.001). Conclusions: Korean older adults showed inadequate protein intake and those in rural area showed lower animal protein intake than in urban area. The risk of obesity and metabolic syndrome was decreased with the increase of protein intake level. These findings may help develop effective nutrition support strategy for older adults to reduce regional health disparity.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.1-13
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• 2012

Metabolic syndrome has become quite prevalent within our society. Over the past two decades, the prevalence of metabolic syndrome has sharply increased worldwide and it has become a major public health problem in several countries. It is associated with the global epidemic of obesity and diabetes mellitus and imposes numerous cardiovascular risks. Prostate cancer is the second most common cancer among men, surpassed only by non-melanoma skin cancer. A considerable body of evidence exists suggesting that some components of the metabolic syndrome have been associated with the risk of prostate cancer. These components include obesity, an abdominal fat distribution, and hyperinsulinemia. Androgen deprivation therapy (ADT) is the most widely used therapeutic modality in prostate cancer. It changed the body composition and lipid profile of men with prostate cancer. Androgen deficiency is associated with increased levels of total cholesterol, low-density lipoprotein (LDL)-cholesterol, increased production of proinflammatory factors, and increased thickness of the arterial wall and contributes to endothelial dysfunction. The aim of this review is to evaluate the association between metabolic syndrome and prostate cancer and to discuss the implications of androgen deficiency in men with cardiovascular risk factors. A comprehensive literature search was carried out with the use of PubMed from 1980 through 2011, and relevant articles pertinent to metabolic syndrome and prostate cancer are evaluated and discussed.

• 한국직업건강간호학회지
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• 제27권4호
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• pp.235-246
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• 2018

Purpose: This study aimed to comprehend the real context of metabolic syndrome-related factors of Korean male blue-collar workers from small-sized companies based on the health belief model. Methods: A total of 37 workers from three companies were interviewed, and three series of focus group interviews were conducted. Data were analyzed using deductive content analysis. Results: Data were classified into four categories: knowledge, perceived susceptibility and severity, perceived barriers, and beliefs. Knowledge referred to low knowledge level; perceived susceptibility and severity referred to unawareness of susceptibility and severity; perceived barriers referred to shift work, overtime work, and a social context including having no choice but to drink; and beliefs referred to believing that health promotion behaviors do not relate to preventing metabolic syndrome, believing that one cannot prevent metabolic syndrome oneself, and believing that professional help is required. Conclusion: To prevent and reduce the risk of metabolic syndrome among Korean male blue-collar workers, interventions should focus on strategies to increase metabolic syndrome-related knowledge and perceptions, social support, and self-efficacy for practicing health behaviors. In addition, it is necessary to develop policies for establishing a healthy drinking culture in companies.

• Journal of Information Technology Applications and Management
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• 제30권1호
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• pp.71-80
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• 2023

The purpose of this study is to promote understanding of physical activity and metabolic syndrome in middle-aged adults and to provide basic data of interventions development for the prevention and management of metabolic syndrome. Using the 2020 data for Korea National Health and Nutrition Examination Survey, 1,786 middle-aged adults between the ages of 40 and 64 with no missing data were analyzed. As a result of the study, 56.5(±2.1)% of men and 52.9(±1.81)% of women were sufficient activity group among physical activity, and the proportion of men was higher than that of women, but it was not statistically significant(t=1.27, p=.207). The prevalence of metabolic syndrome was 38.9(±2.1%) of men and 25.4(±1.5)% of women, the prevalence of men was significantly higher than that of women(t=5.12, p<.001). Compared to the insufficient activity group, the sufficient activity group had a 0.71(95% CI: 0.57~0.88) times the risk of developing low HDL(high density lipoprotein)- cholesterol(p=.002), and this pattern was maintained even after adjusting for age, education level, body mass index, smoking status, and drinking status(p=.002). Based on the results of this study, a physical activity and metabolic syndrome risk group in middle-aged adults should be selected, and physical activity promotion program to improve high density lipoprotein-cholesterol among metabolic syndrome indicators should be developed.

• 한국환경보건학회지
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• 제41권5호
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• pp.335-348
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• 2015

Objectives: We aimed to assess the risk of metabolic syndrome one year after the 2007 Hebei Spirit oil spill in Taean, Korea among people exposed to spilt oil during clean-up work. Methods: A total of 6,923 adults, including 3,019 males and 3,904 females, participated in the study. Health examinations and blood tests (total cholesterol, triglycerides, HDL, fasting blood sugar) were performed. A logistic regression model adjusting for age, gender, smoking history, drinking history, income, education, and marital status was used to estimate the risk of metabolic syndrome associated with the level of oil spill exposure. Results: The prevalence of metabolic syndrome was 24.9% among males and 18% among females. Compared with people living within 20 km of the coastline, the risk of metabolic syndrome among people living within 0.8 km of the coastline was significantly higher (male OR=1.696, 95% CI=1.320-2.178, female OR=1.992, 95% CI=1.549-2.561), including a significant dose-response relationship for distance from early contaminate coastline (p<0.001). The risk of metabolic syndrome was higher according to the increase of duration of cleaning work. The risk of metabolic syndrome among people who participated in the clean-up work for more than 116 days, compared with people who participated in the cleaning work for or less 14 days, was significantly higher (male OR=1.845, 95% CI=1.448-2.353, female OR=1.752, CI=1.378-2.228), with a significant dose-response relationship for days of clean-up work (p<0.001). Conclusion: This study showed that there is a significant association between exposure to the oil spill during the clean-up work, distance from early contaminate coastline and the risk of metabolic syndrome in a doseresponse manner.