• 한국심리학회지 : 문화 및 사회문제
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• 제17권1호
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• pp.63-79
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• 2011

본 연구의 목적은 청소년의 분노표현 양식과 지각된 정서적 유능성이 학교분노에 미치는 효과를 조사하는 것이다. 이를 위해 본 연구에서는 고등학생 304명(남자 134명, 여자 170명)에게 한국판 상태-특성 분노표현 척도(Korean Version of State-Trait Anger Expression Inventory; STAXI-K) 중 분노표현 양식 척도(분노표출, 분노억제, 분노통제), 한국판 학교분노 척도(Korean Version of School Anger Inventory), 그리고 한국판 특성 메타-기분 척도(Korean Version of Trait Meta-Mood Scale; K-TMMS)를 실시하였다. 본 연구 결과, 학교분노는 분노표출 및 분노억제와는 정적인 상관을 그리고 분노통제 및 지각된 정서적 유능성과는 부적인 상관을 보였다. 학교분노에 대한 분노표출과 지각된 정서적 유능성의 상호작용 효과 그리고 학교분노에 대한 분노억제와 지각된 정서적 유능성의 상호작용 효과는 유의미하지 않았다. 반면에 학교분노에 대한 분노통제와 지각된 정서적 유능성의 상호작용 효과는 유의미한 것으로 나타났다. 사후분석에서 지각된 정서적 유능성 점수가 낮은 경우에는 학교분노에 대한 분노 통제의 효과가 유의미하지 않은 반면에 지각된 정서적 유능성 점수가 높은 경우에는 학교분노에 대한 분노 통제의 효과가 유의미한 것으로 나타났다. 이러한 결과에 기초하여 청소년의 학교분노 수준을 경감시키기 위한 심리학적인 프로그램에서 분노통제의 기술과 더불어 지각된 정서적 유능성을 높일 수 있는 방안을 함께 다루어야 할 필요성이 논의되었다.

• 미술이론과 현장
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• 제16호
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• pp.7-40
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• 2013

Historian Eric J. Hobsbawm once said "the task that historians have is to analyze the meanings of the past within the context of society and to track the changes and implementation." It would not be too far of a stretch to apply Hobsbawm's quote to art historian since art history, although quite specific, is still history. In addition, Hobsbaum also asserted that, "a mold called the past continuously forms the present or at least thought to be." It is my recognition that the major westernization of the last century took place under the Japanese colonization which served as the channel to usher in western art; however, the current 20thcentury Korean art history fails to recognize that the mold of the past, namely western art in this case, has formed the modern art of the present. Based on this recognition, attention was given to what lacked in the analysis of the current 20th-century Korean art history in terms of "Informel" which was identified as the turning point towards "modern art" in the Korean art history as well as the following "experimental art." My belief is that the art history of Korea has to be reassessed from, a socio-cultural perspective as well as adopting multi-level and diachronic understanding. However, the existing Korean art, especially the one between the end of 1950s to the 1970s was based on the perspective of "severance"; thus, raising the needs for the starting point of a new perspective. It is my conviction that meta perspective on writing is most essential in order to lay a solid basis for the Korean art scene to have a productive discussion. I feel the utmost necessity to reinterpret the typified history analysis and criticism which stemmed from the trauma under the Japanese colonization. The most urgent task is to avoid academic closeness and to share the research. Painting is an individual expression of the artist, but the act of expression is not free from the cultural and societal influence to which the artist belongs.

• 미생물학회지
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• 제30권1호
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• pp.1-7
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• 1992

Pseudomonas sp. DJ77 의 chromosomal DNA로 부터 6-8kb XhoI 절편 상에 존재하는 phenanthrene 분해에 관련된 유전자군을 vector pBLUESCRIPT SK(+)에 클로닝하였다. 이렇게 얻은 재조합 plasmid인 pHENX7을 가지고 있는 JM101 균주는 3-methylcatechol을 노란색의 meta-cleavage 화합물로 전환학 수 있었다. 그러자 삽입된 절편의 방향이 반대가 되도록 제조한 pHENX7R 은 extradiol dioxygenase 활성을 나타내지 않기 때문에 전사방향을 알 수 있었다. pHENX7과 이의 유도체들을 지니는 JM101 균주에서 PhnC(24kDa), PhnD(31 kDa), PhnE(34 kDA), PhnF(15 kDa) 의 4 polypeptide 를 확인학 수 있었고 개개의 유전자의 위치와 범위를 알 수 있었다. 유전자 순서는 phnC-phnD-phnE-phnF-phnG 이었으며, phnD, phnE, phnG 는 각기 gluthione S-transferase, meta-cleavage compound hydrolase, extradiol dioxygenase, metacleavage compound dehydrogenase 의 유전자이었다.

• 대한두개안면성형외과학회지
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• 제24권6호
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• pp.251-259
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• 2023

Background: Periosteum-mediated bone regeneration (PMBR) is a recognized method for mandibular reconstruction. Despite its unpredictable nature and the limited degree to which it is understood, it does not share the concerns of developmental changes to donor and recipient tissues that other treatment options do. The definitive role of the periosteum in bone regeneration in any mammal remains largely unexplored. The purpose of this study was to identify the genetic determinants of PMBR in mammals through a systematic review. Methods: Our search methodology was designed in accordance with the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. We conducted a quality assessment of each publication, and evaluated the differences in gene expression between days 7 and 15. Results: A total of four studies satisfied the inclusion criteria. The subjects and tissues examined in these studies were Wistar rat calvaria in two studies, mini-pigs in one study, and calves and mice in one study. Three out of the four studies achieved the necessary quality score of ≥ 3. Gene expression analysis showed increased activity of genes responsible for angiogenesis, cytokine activities, and immune-inflammatory responses on day 7. Additionally, genes related to skeletal development and signaling pathways were upregulated on day 15. Conclusions: The results suggest that skeletal morphogenesis is regulated by genes associated with skeletal development, and the gene expression patterns of PMBR may be characterized by specific pathways.

• Molecules and Cells
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• 제37권2호
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• pp.118-125
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• 2014

Osteosarcoma is the most common primary malignant bone tumor with a very poor prognosis. Treating osteosarcoma remains a challenge due to its high transitivity. Tenascin-C, with large molecular weight variants including different combinations of its alternative spliced FNIII repeats, is specifically over expressed in tumor tissues. This study examined the expression of Tenascin-C FNIIIA1 in osteosarcoma tissues, and estimated the effect of mechanical stimulation on A1 expression in MG-63 cells. Through immunohistochemical analysis, we found that the A1 protein was expressed at a higher level in osteosarcoma tissues than in adjacent normal tissues. By cell migration assay, we observed that there was a significant correlation between A1 expression and MG-63 cell migration. The relation is that Tenascin-C FNIIIA1 can promote MG-63 cell migration. According to our further study into the effect of mechanical stimulation on A1 expression in MG-63 cells, the mRNA and protein levels of A1 were significantly up-regulated under mechanical stress with the mTOR molecule proving indispensable. Meanwhile, 4E-BP1 and S6K1 (downstream molecule of mTOR) are necessary for A1 normal expression in MG-63 cells whether or not mechanical stress has been encountered. We found that Tenascin-C FNIIIA1 is over-expressed in osteosar-coma tissues and can promote MG-63 cell migration. Furthermore, mechanical stress can facilitate MG-63 cell migration though facilitating A1 overexpression with the necessary molecules (mTOR, 4E-BP1 and S6K1). In con-clusion, high expression of A1 may promote the meta-stasis of osteosarcoma by facilitating MG-63 cell migration. Tenascin-C FNIIIA1 could be used as an indicator in metastatic osteosarcoma patients.

• 성인간호학회지
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• 제20권2호
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• pp.280-295
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• 2008

Purpose: This ethnography in communication aimed to explore the changes in consciousness on time and temporality as an elderly became older. This study focused on time as a primary message systems of Edward Hall. Methods: The assumption of the study was that the aging body as an expression of biological time is a meta of physical, personal, and social time. Data were collected from iterative fieldwork in a clan between Jan, 1990 and April, 2007. The key informants were 13 women and men aged 70 years old or more at the beginning of study. Changes in physical time and temporality as the women's body declined in its physical function was analyzed. As the cultural context, informants' every life and the history of the clan were also analyzed. Results: The meta-time of the informants were constituted as follows: In the low-contextual dimension, physical time perceived as longer and personal time perceived as shorter than they were young; In high-contextual dimension, informant and residents had a polychronic perspective and aged-centered time perspectives.; In the supernatural dimension of time, sacred time were reinforced by rituals. Informants extended temporality to their springs' world and ancestors' world. Conclusion: As the informants recognized slugged body movements and time-limited present life, their views on their life world towards the future of spring and of the sacred world of ancestors. Thereby, their identity as a member of a clan was reinforced. This result informed us on what we should focus on when caring with older women.

• 미생물학회지
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• 제33권1호
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• pp.22-26
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• 1997

Pseudomonas sp. DJ77의 게놈 library로부터 phenanthrene 분해에 관련된 유전자를 포함하는 약 5-kb의 XhoI 절편을 pBLUESCRIPT SK(+)로 클로닝하였으며, 이 재조합 plasmid를 pUPX5라 명명하였다. 이 재조합 균주에 catechol과 2,3-dihydroxybiphenyl 용액을 분무하면 노란색의 meta-cleavage 화합물이 생성됨을 관찰 할 수 있었다. 그리고 효소 활성을 측정한 결과 catechol에서보다 2,3-dihydroxybiphenyl에 더 큰 활성을 나타냈다. 이 부분에 존재하는 2,3-dihydroxybiphenyl 1,2-dioxygenase 유전자의 위치를 결정하고, 이 유전자를 phnQ라 명명하였다.

• Physical Therapy Rehabilitation Science
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• 제11권3호
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• pp.304-310
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• 2022

Objective: Mild cognitive impairment (MCI) is a condition in which cognitive and executive functions are reduced, and older adults with MCI are ten times more likely to develop dementia than healthy older adults. Expression of brain-derived neurotrophic factor (BDNF) through aerobic exercise is associated with increased cognitive and executive functions. in this review, randomized controlled trials (RCTs) on the effects of aerobic exercise on BDNF in individuals with mild cognitive impairment are summarized and qualitatively and quantitatively analyzed to suggest the necessity of aerobic exercise. Design: a systematic review and meta-analysis. Methods: RCTs were searched for changes in BDNF through aerobic exercise using four international databases. Quality assessment and quantitative analysis were performed using RevMan 5.4. Quantitative analysis was quantified with a standardized mean difference (SMD) and presented as a random effect model. Results: Three RCTs evaluated BDNF in 123 patients with MCI. There was a significant improvement in the experimental group that performed aerobic exercise compared to the control group. The results analyzed using the random effects model were SMD = 0.48. Conclusions: In this review, we reported the effects and mechanisms of aerobic exercise in individuals with MCI. As a result of synthesizing RCTs that performed aerobic exercise, a significant increase in BDNF was confirmed.

• 한국실내디자인학회논문집
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• 제22권2호
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• pp.68-80
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• 2013

This study is about expressive aspects of subversive mimesis found in architectural design under 2nd Modernity. Architectural works under 2nd Modernity are described based on pseudo-scientific positivism and philosophical ontology of Deleuze. However, subversiveness found in works of arts by architects such as Rem Koolhaas present a few complexities to relay on such a description. This is about 'subversiveness' which absorbs the positive and negative factors of modernity which has been multi-layered as 'cultural capital'. This study aims to identify meta-phenomenon as well as the specific correlations between expression and purposes of any work of art that is presented in the form of subversiveness. To achieve this aim, this study approached with the concepts of appropriation and detournment based on Adorno's subversive mimesis concept. Meta-phenomena of architectural design methods occur from relations of three, which are social reality, artist, and work of art. This was connected to productivity of mimesis practice of self-reference and self-examination, which was then, summed up from the perspectives of appropriation in pure arts and d$\acute{e}$tournment of situationalists. Based on this work, subversive expressive characteristics of architecture under 2nd Modernity were framed from the perspectives of the absorption of cultural capital, reflection and negation, autonomy, instrumentality, and meta properties. In this way, this study found that Adorno's subversiveness should be effective for creative and methodological systemization in terms of interpretation of cognition, practice, and effect after materialization.

• Structural Engineering and Mechanics
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• 제62권6호
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• pp.749-758
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• 2017

In structural mechanics, traditional analyses methods usually employ matrix operations for obtaining displacement and internal forces of the structure under the external effects, such as distributed loads, earthquake or wind excitations, and temperature changing inter alia. These matrices are derived from the well-known principle of mechanics called minimum potential energy. According to this principle, a system can be in the equilibrium state only in case when the total potential energy of system is minimum. A close examination of the expression of the well-known equilibrium condition for linear problems, $P=K{\Delta}$, where P is the load vector, K is the stiffness matrix and ${\Delta}$ is the displacement vector, it is seen that, basically this principle searches the displacement set (or deformed shape) for a system that minimizes the total potential energy of it. Instead of using mathematical operations used in the conventional methods, with a different formulation, meta-heuristic algorithms can also be used for solving this minimization problem by defining total potential energy as objective function and displacements as design variables. Based on this idea the technique called Total Potential Optimization using Meta-heuristic Algorithms (TPO/MA) is proposed. The method has been successfully applied for linear and non-linear analyses of trusses and truss-like structures, and the results have shown that the approach is much more successful than conventional methods, especially for analyses of non-linear systems. In this study, the application of TPO/MA, with Harmony Search as the selected meta-heuristic algorithm, to cables net system is presented. The results have shown that the method is robust, powerful and accurate.