• 벤처혁신연구
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• 제2권1호
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• pp.33-55
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• 2019

최근 들어 기업의 사회적 책임(CSR)에 대한 인식이 달라지고 있다. 지금까지 기업의 사회적 책임은 기업의 이미지 개선을 위해 일시적 방편 정도로 인식되었으나 기업의 지속성장을 위한 필수요건이라는 인식이 확산되고 있다. 기업의 사회적 책임은 시대나 경제환경에 따라 변해 왔으며 특히 글로벌 가치사슬이 중요해지면서 수출중소기업의 성장전략으로 자리잡게 되었다. 이러한 상황에서 CSR은 기업의 활동에 점점 필수불가결한 영역이 되고 있으며 이는 중소기업에게도 예외가 아니라고 할 수 있다. 그럼에도 아직 우리나라의 중소기업 CSR은 미진한 상황이며, 그렇기에 짧은 기간에도 불구하고 중소기업까지 CSR이 확산된 일본의 사례는 우리에게 정책적 시사점을 줄 수 있다고 판단된다. 일본의 경우 기업의 사회적 책임은 17세기 오미 상인들로부터 전통으로 내려왔다. 이들이 생각한 기업의 사회적 책임은 판매자에게 이롭고 구매자에게 이득이 있으며 사회에도 도움이 되어야 한다는 이른바 산포요시 정신으로 요약된다. 이런 전통이 일본의 중소기업들에게까지 순조롭게 적용된 일본의 CSR 사례를 바탕으로 다음과 같은 정책적 시사점을 제공하고자 한다. 첫째 국가적인 장기계획의 수립 및 보급이 필요하다는 점이다. 둘째 중소기업의 전략적 CSR 도입이 시급하다는 점이다. 셋째 대기업과 중소기업이 상생 협력하는 CSR을 추진해야 한다는 것이다.

• 기술혁신연구
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• 제22권2호
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• pp.77-104
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• 2014

중소기업 R&D지원은 정책적으로 매우 중요하며 예산 또한 매년 증가하고 있다. 본 연구에서는 중소기업 R&D지원에 대한 성과를 종합적이고 체계적으로 분석할 수 있는 새로운 성과분석 방법을 제안하며 이 모델을 기반으로 중소기업청의 대표적인 R&D지원 사업에 대하여 실증분석하였다. 중소기업 R&D지원사업의 성과는 시차(time-lag)를 두고 발생하는데 이때, 단기적인 성과를 효율성, 중 장기적인 성과를 효과성으로 측정하였다. 효율성과 효과성을 나타내는 지표는 과거 선행연구를 기반으로 선정했으며 분석대상 사업별 사업목적, 취지, 내용 등의 특성을 반영하기 위해 지표별 가중치를 도출하였다. 이렇게 효율성과 효과성의 최종 점수가 도출되고 각 사업별 성과의 차이를 통계 검정하였다. 분석 결과, 중소기업청의 5개 R&D지원사업의 효율성은 통계적으로 유의한 차이를 나타냈으며 효과성은 통계적으로 차이가 없었다. 효율성 점수는 전반적으로 낮게 나타나며 효과성 점수는 보통이상으로 높은 수준을 보였다. 중소기업청의 R&D지원사업은 대체로 단기적인 성과인 효율성이 낮아 R&D수행상의 비효율을 초래하는 것으로 나타나는 반면, 중 장기적인 효과성에 대한 기대는 높아 R&D수행을 통한 사회경제적 파급효과는 클 것으로 예상된다. 그러나 효율성이 개선되지 않고는 지속적인 성과를 기대하기 힘들기 때문에 이에 대한 정책적 노력이 필요하다.

• Asian-Australasian Journal of Animal Sciences
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• 제29권10호
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• pp.1407-1415
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• 2016

Isolation and culture of spermatogonial stem cells (SSCs) are attractive for production of genetic modified offspring. In the present study, buffalo spermatogonial stem-like cells were isolated, cultured and expression pattern of different germ cell marker genes were determined. To recover spermatogonia, testes from age 3 to 7 months of buffalo were decapsulated, and seminiferous tubules were enzymatically dissociated. Two types of cells, immature sertoli cell and type A spermatogonia were observed in buffalo testes in this stage. Germ cell marker genes, OCT3/4 (Pou5f1), THY-1, c-kit, PGP9.5 (UCHL-1) and Dolichos biflorus agglutinin, were determined to be expressed both in mRNA and protein level by reverse transcription polymerase chain reaction and immunostaining in buffalo testes and buffalo spermatogonial stem-like cells, respectively. In the following, when the isolated buffalo buffalo spermatogonial stem-like cells were cultured in the medium supplemented 2.5% fetal bovine serum and 40 ng/mL glial cell-derived neurotrophic factor medium, SSCs proliferation efficiency and colony number were significantly improved than those of other groups (p<0.05). These findings may help in isolation and establishing long term in vitro culture system for buffalo spermatogonial stem-like cells, and accelerating the generation of genetic modified buffaloes.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6875-6881
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• 2013

Background: Studies evaluating smoking cessation treatment outcomes in cancer patients are scarce, despite smoking cessation importance in cancer care. We sought to add to the literature by evaluating smoking cessation in a challenging group of cancer patients (medium-to-heavy smokers) visiting an out-patient smoking cessation clinic (SCC) in a cancer center in Amman, Jordan. Materials and Methods: Patients smoking >9 cigarettes per day (CPD) and referred to the SCC between June 2009 and May 2012 were studied. Clinic records were reviewed to measure demographic and baseline clinical characteristics, and longitudinal (3-, 6- and 12- month) follow-up by phone/clinic visit was conducted. At each follow-up, patients were asked if they experienced medication side-effects, if they had returned to smoking, and reasons for failing to abstain. Descriptive and multivariable logistic regression analyses were performed. Results: A total of 201 smokers were included in the analysis. The 3-month abstinence was 23.4% and significantly associated with older age, being married, and presenting with lower (${\leq}10ppm$) baseline carbon monoxide (CO) levels. On a multivariable level, lower CO levels, a higher income (relative to the lowest income group), being older, and reporting severe dependence (relative to dependence reported as 'somewhat' or 'not') were significant predictors of higher odds of abstinence at three months. Reasons for failing to quit included not being able to handle withdrawal and seeing no value in quitting. Long-term ARs did not reach 7%. Conclusions: In a sample of Jordanian smokers (>9CPD) with cancer and receiving smoking cessation treatment, ARs were low and further declined with time. Results underscore the need for more aggressive patient management and rigorous follow-up during and after smoking cessation treatment, particularly when this takes place in challenging settings. Observed reasons for failure to abstain should be used to tailor counseling practices.

• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.4973-4977
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• 2012

Introduction: Tobacco use is a global health care problem. Repetitive exposure to nicotine produces neuroadaptation resulting in nicotine dependence. Smoking is associated with a range of diseases, causing high levels of morbidity and mortality and is one of the leading causes of preventable deaths, with more than 4.6 million smokers worldwide dying each year from smoking related illnesses. Stopping smoking has major health benefits. Quitting at any age provides both short and long term benefits. Materials and methods: 45 patients attending the outpatient department at the Oxford Dental College, Bangalore, were randomly allocated to three groups of interventions namely placebo, counseling and nicotine replacement therapy (NRT). Initially each one was assessed for carbon monoxide levels using a breath analyser (pico smokerlyser bedfont UK). They were followed up for six months and the carbon monoxide levels were again assessed using the same instrument. The paired t test was used to compare the results before and after the intervention. Results: The scores before the initiation of intervention and after treatment were compared and all three interventions were found to be statistically significant after six months. It was noticed that patients with very low or low dependence followed by high dependence had good response in the placebo group (68% and 47.6% respectively), in the counseling group maximum response was seen in the medium followed by the very low group (61% and 59% respectively), and maximum response was seen in very high followed by the very low group with NRT (78.7% and 60.5% respectively). Conclusion: The inference that can be drawn from the present study is that non-invasive, non pharmacological methods like placebo and counseling are effective in low to medium groups, and NRT is effective with higher nicotine dependence.

• Journal of Plant Biotechnology
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• 제36권2호
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• pp.193-196
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• 2009

Pinellia koreana K-H Tae & J-H Kim is a recently discovered Korea endemic medicinal plant species whose natural habitat is rapidly destroyed by industrial development. Described in this paper are culture conditions for high frequency plant regeneration via bulblet formation from leaf explant cultures of P. koreana. Leaf explants formed white nodular structures and off-white calluses at a frequency of 91.2% when cultured on MS medium supplemented with 2 mg/L BA and 0.5 mg/L NAA. However, the frequency of white nodular structures and off-white calluses formation was slightly decreased with an increasing concentration of NAA up to 4 mg/L, where the frequency reached 31.7%. Most petiole explants did not form white nodular structures and off-white calluses except the combination treatment of 2 mg/L BA and 2 mg/L NAA. Upon transfer onto MS basal medium, over 90% of nodular structures gave rise to numerous bulblets and developed into plantlets. Plantlets regenerated from bulblets were transplanted to potting soil and grown to maturity at a survival rate of over 95% in a growth chamber. Therefore, the in vitro plant regeneration system of P. koreana obtained in this study will be useful for mass propagation and long-term preservation of genetic resources of P. koreana.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2023년도 임시총회 및 춘계학술대회
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• pp.33-33
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• 2023

Potatoes are the world's 4th major food crop after maize, rice, and wheat and also are a staple food for 1.3 billion people. Due to their wide adaptability to various environmental conditions, their yeild capacity, and high commercial value, potatoes have contributed to global food security. Many potato germplasms are commonly preserved as whole plants in fields or in storage to maintain their particular genetic combinations. However, field maintenance is expensive and has the risk of potential losses from diseases, pests, plant ageing and climate change. Over the past four decades, meaningful efforts have been made toward the safe long-term conservation of potatoes through cryopreservation methods such as droplet-vitrification. In this study, we tested 4 Korean potato varieties('Golden Egg', 'Golden Ball', 'Ja-Young' and 'Ha-Ryeong') with the modified potato droplet -vitrification protocol. Potato shoot tips are precultured in a sucrose-enriched medium(0.3 and 0.7M for 7 and 17hrs, respectively) and submitted to a loading step with C4 solution for osmoprotection. The treated explants were dehydrated with Plant Vitrification Solution(PVS)2 which is 80% A3 solution in ice for 30 minutes. Thawing and unloading steps were performed with 0.8M sucrose solution for 30 sec(40℃) followed by 30min(25℃, room temperature). In a potato post-culture medium(MS+0.1 mg·L^-1 GA₃+0.1 mg·L^-1 kinetin), we obtained a survival rates of post-thawed explants ranging 16.1-82.2%. The results suggest that modified and optimized protocols are required dependinig on every cultivar, genetic and ecological types. To achieve higher survival and regeneration rates, each step within the cryoprocedure must be carefully optimized.

• 한국식품과학회지
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• 제22권3호
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• pp.266-271
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• 1990

콩기름으로 팽화시킨 유과의 저장가능 시간을 확인하고 저장 중 물리화학적 변화를 관찰하였으며 팽화매체를 대체하기 위하여 공기팽화를 시도하였다. 기름팽화 유과의 저장가능 기간은 $30^{\circ}C$에서 4주 이내였으며 9주 저장 중 조직의 물리적 변화는 미미하였다. 고온 공기에 의하여 유과의 팽화는 가능하였고 최적 팽화온도는 $250^{\circ}C$였으며, 기름팽화 유과와 비교할 때 팽화도는 떨어지나 경도는 비슷하였고 아삭아삭한 정도는 높았다. 공기팽화 유과는 기름팽화 유과에 비하여 냄새, 굳은 정도 및 조직에서 관능적인 차이가 없으나 맛은 떨어지는 결과였고 이는 기름 맛에 기인하는 것으로 보고 이의 개선이 필요하였다. 팽화된 조직의 형태는 팽화매체에 따라 차이가 없었다.

• Journal of Forest and Environmental Science
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• 제25권1호
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• pp.35-41
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• 2009

Agroforestry combines agriculture and forestry technologies to create more integrated, diverse, productive, profitable, healthy and sustainable land-use systems. This study was performed in three union of Chhagalnaiya Upazila (Sub-district; administrative entity) under Feni district, Southern Bangladesh with a view to identify the tree resources, utilization pattern and economic return of major fruit and timber tree species. Information collected from a total of 45 households ranging from marginal, small, medium and large categories. Number of plant species increased with the increase of homestead area. A total of 39 plant species were recorded from the homegarden, of which 23 were fruit and 16 were timber tree species. Considerable number of vegetables was also planted under the shade of the homestead trees. The investment analysis showed that average benefit-cost ratios were greater than one, net present values were positive and internal rate of returns were more than 10%. Long term investment on horticulture and timber tree species is highly profitable if species like Swietenia mahagoni and Tectona grandis, Spondias pinnata, Syzygium cumini and Areca catechu were planted.

• Biomolecules & Therapeutics
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• 제22권6호
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• pp.570-576
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• 2014

Studies have demonstrated that electromagnetic waves, as the one of the most important physical factors, may alter cognitive and non-cognitive behaviors, depending on the frequency and energy. Moreover, non-ionizing radiation of low energy waves e.g. very low frequency waves could alter this phenomenon via alterations in neurotransmitters and neurohormones. In this study, short, medium, and long-term exposure to the extremely low frequency electromagnetic field (ELF-EMF) (1 and 5 Hz radiation) on behavioral, hormonal, and metabolic changes in male Wistar rats (250 g) were studied. In addition, changes in plasma concentrations for two main stress hormones, noradrenaline and adrenocorticotropic hormone (ACTH) were evaluated. ELF-EMF exposure did not alter body weight, and food and water intake. Plasma glucose level was increased and decreased in the groups which exposed to the 5 and 1Hz wave, respectively. Plasma ACTH concentration increased in both using frequencies, whereas noradrenaline concentration showed overall reduction. At last, numbers of rearing, sniffing, locomotor activity was increased in group receiving 5 Hz wave over the time. In conclusions, these data showed that the effects of 1 and 5 Hz on the hormonal, metabolic and stress-like behaviors may be different. Moreover, the influence of waves on stress system is depending on time of exposure.