• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3119-3121
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• 2012

Non-small-cell lung cancer (NSCLC) is a leading cause of cancer deaths worldwide. Crizotinib has been approved by the U.S. Food and Drug Administration for the treatment of patients with advanced NSCLC. However, understanding of mechanisms of action is still limited. In our studies, we confirmed crizotinib-induced apoptosis in A549 lung cancer cells. In order to assess mechanisms, small molecular docking technology was used as a preliminary simulation of signaling pathways. Interesting, our results of experiments were consistent with the results of computer simulation. This indicates that small molecular docking technology should find wide use for its reliability and convenience.

• 대한의용생체공학회:의공학회지
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• 제41권4호
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• pp.154-164
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• 2020

Various simulator systems for surgery training have been developed and recently become more widely utilized with technology advancement and change in medical education adopting actively simulation-based training. The authors have developed tissue-instrument interaction modeling and graphical simulation algorithms for an arthroscopic surgery training simulator system. In this paper, we propose algorithms for basic surgical techniques, such as cutting, shaving, drilling, grasping, suturing and knot tying for rotator cuff surgery. The proposed method constructs a virtual 3-dimensional model from actual patient data and implements a real-time deformation of the surgical object model through interaction between ten types of arthroscopic surgical tools and a surgical object model. The implementation is based on the Simulation Open Framework Architecture (SOFA, Inria Foundation, France) and custom algorithms were implemented as pulg-in codes. Qualitative review of the developed results by physicians showed both feasibility and limitations of the system for actual use in surgery training.

• 한국응급구조학회지
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• 제22권2호
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• pp.93-102
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• 2018

Purpose: The study aims to establish an effective training strategy and methods by comparing the effects of educational interest, satisfaction, and achievements of virtual reality and videos education before simulation training. Methods: The randomized control study was implemented on May 31, 2018, by randomly selecting 36 participants to compare educational virtual reality and videos. Statistical analyses were performed using SPSS 20.0. Results: The participants were divided into an intervention group of 17(47.2%) and a control group of 19(52.8%). Regarding the levels of satisfaction, a significant difference (p= .010) was noted between the control (3.88 points) and the intervention groups (4.45 points). A significant difference (p= .001) was also noted between the intervention (80.3 points) and control (63.3 points) in terms of total simulation practical skills. Conclusion: Educational virtual reality can be an alternative training method to achieve the standard educational objectives by raising levels of educational interest and of achievement with practical skills.

• 한국응급구조학회지
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• 제15권2호
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• pp.55-66
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• 2011

Purpose: The purpose of this study was to develop a scenario and evaluate the performance of paramedic students in head trauma simulation education. Method: This study selected a refined head trauma scenario that was developed by graduate students during class from september to November, 2010. Evaluation on implementation of head trauma simulation was conducted on seventeen paramedic students divided into four groups during November, 2010. Results: 1. The head trauma scenario was developed according to the patient assessment for approximately 10 minutes. It contained scene size-up, initial assessment and intervention, rapid trauma assessment and intervention, and decision of transfer. 2. The average time turned out to be 9 min and 36 sec after simulation learning. Total mean score in simulation performance was 2.20, the highest score was 2.44 in initial assessment and intervention, and the lowest score was 1.5 in decision of transfer. 3. Confidence mean was high with the score of 1.0. Conclusion: The finding of this study demonstrate that the simulation education can improve problem-solving ability and critical thinking, and increase the confidence in prehospital emergency care; therefore, simulation may be the new effective paramedic education strategy and simulation learning is needed for further development of various scenarios.

• 한국응급구조학회지
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• 제25권3호
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• pp.111-125
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• 2021

Purpose: This study aimed to analyze the impact of rapid cycle deliberate practice (RCDP) simulation education on advanced cardiac life support knowledge, confidence, satisfaction, and performance ability among paramedic students, and provide basic data on the appropriate methods of educational instruction. Methods: The 48 subjects to be instructed were divided into the traditional simulation education group and the RCDP simulation education group. Six participants were randomly assigned to each group and pre-surveyed. They were then exposed to a lecture about advanced cardiac life support related theories for 60 min and post-surveyed through questionnaires with the same learning goals and scenarios. Results: The advanced cardiac life support knowledge (t=-4.813, p=.000) and performance ability (t=-2.903, p=.006) were significantly different between the traditional simulation education and RCDP simulation education groups The results also showed a significant difference in attach monitor (z=6.857, p=.009), analyze EKG rhythm (z=11.111, p=.001), and defibrillation (z=12.632, p=.000), indicating differences in performance capabilities between the two groups. Conclusion: To improve advanced cardiac life support knowledge, performance ability, and confidence in the paramedic students who receive RCDP simulation education, simulation education methods that are appropriate for the subjects being taught, and detailed learning goals and feedback are necessary.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2006년도 제33회 추계학술대회 발표논문집
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• pp.140-140
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• 2006

• 한국멀티미디어학회논문지
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• 제14권9호
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• pp.1175-1181
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• 2011

최근 의료 환경에 도입되고 있는 가상 의료 시뮬레이션을 통한 실습 교육은 학습 효과를 최대화한다. 특히 최소 침습적 수술 분야에서 가상 수술 의료 시뮬레이션의 필요성이 매우 증가하고 있다. 최소 침습적 수술 환경에서 많이 발생하는 소작 효과는 단순 출혈 효과로 표현되고 있어 아직까지 현실감이 있는 소작 효과 애니메이션 기술은 제안되지 않고 있다. 본 논문에서는 사실적인 실시간 소작 애니메이션 기법을 제안한 다. 제안 기법은 메쉬의 정점에 대한 칼라 값을 구성하는 각 요소 색상을 개별적으로 변화시키고, sigmoid 함수를 이용한 가중치 부여로 유효 영역 메쉬 내부의 부드러운 색상 변화를 통하여 사실적이고, 자연스러운 소작 효과의 애니메이션이 가능하였다. 또한, 소작 칼라 버퍼를 제안하여 중첩된 소작 효과 애니메이션도 자연스럽게 표현하였다. 본 논문에서 제안한 기법은 가상 수술 의료 시뮬레이션의 현실감, 몰입감을 크게 증진시켜 이러한 시뮬레이션을 사용하는 의사 혹은 의대생들에 대한 교육의 효과를 극대화시킬 수 있다.

• Journal of International Society for Simulation Surgery
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• 제2권2호
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• pp.76-79
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• 2015

One of the most serious complications after head and neck radiation is osteoradionecrosis (ORN) of the jaw. The etiology of ORN is extraction, minor dental procedure or dental implant surgery. When ORN of the jaw progressed to stage III, free fibular flap is the most useful methods for reconstruction. In this case report, a 67-year-old ORN patient who underwent fibular free flap reconstruction using simulation surgery with 3-dimensional rapid prototype (3D RP) model was reviewed. After partial mandibulectomy, a osteocutaneous fibula flap was used for reconstruction. Oro-cutaneous fistula was resolved after operation. Patients reported improved food intake after operation without pus discharge. Functional and esthetic results showed successful reconstruction.

• 한국응급구조학회지
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• 제28권2호
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• pp.131-142
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• 2024

Purpose: This study aimed to explore the use of web-based virtual simulations to improve the learning flow, problem-solving ability, and academic self-efficacy of paramedicine students. Methods: This study used a pre-post comparison design with 40 pamedicine students at one university. the participants were third grade students and participated in web based virtual simulation(vSim®). The difference between the pre-post was analyzed using a Paired Sample t-test with SPSS 26.0. Results: After web based virtual simulation using vSim® program than before, significantly higher learning flow(t=12.74, p<.001), problem-solving process(t=5.78, p<.001), academic self-efficacy(t=2.77, p<.001), Paramedic-Care Skills Confidence(t=6.30, p<.001). Conclusion: The results indicated the positive effects of web-based virtual simulation(vSim®) learning method and suggests implications for learners and instructors.

• Journal of Yeungnam Medical Science
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• 제24권2호
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• pp.148-153
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• 2007

배경 : 의학시뮬레이션 교육방법이 새로이 도입되면서 다양한 방법이 개발되었다. 특히 컴퓨터와 인터넷을 이용한 시뮬레이션 교육이 학생들에게 사전에 임상수기 교육 및 임상경험을 가능하게 하여 많은 도움을 주고 있다. 본 연구는 $Microsim^{(R)}$ 프로그램을 이용한 학생들의 첫 경험을 보고하고 컴퓨터와 인터넷을 이용한 시뮬레이션 교육에 대하여 소개하고자 한다. 대상 및 방법 : 의학과 3학년 학생을 대상으로 임상의학입문 과정의 일환으로 $Microsim^{(R)}$ 프로그램을 이용하여 2주간의 실습후 획득한 점수를 산정하여 통과여부를 알아보고자 하였다. 모듈 1은 기도 및 호흡, 모듈 2는 심정지, 모듈 3은 심장 부정맥, 모듈 4는 흉통으로 정하였으며, 4개의 모듈에서 미리 지정된 각각의 증례하나를 선택하여 반복하여 실습하고 최종적으로 각각 통과점수가 70% 이상이 되어야 인정되도록 하였다. 결과 : 전체 75명의 학생이 참가하여 이중 56명(74.7%)이 4개의 모듈을 모두 통과하였다. 각각의 모듈의 평균 통과율은 모듈 1이 86.7%, 모듈 2가 85.3%, 모듈 3과 4가 각각 84.0%였으며, 4개 모듈의 평균점수는 88.6이었다. 결론 : 의학시뮬레이션이 비록 완전하게 통과되지는 않았지만 학생들로 하여금 실제적인 임상경험을 가능하게 하였다. 하지만 이는 아직은 기존의 교육방식의 보조적인 역할을 담당한다고 할 수 있으며 향후 좀 더 다양한 방법으로 반복된 시뮬레이션 교육과 이에 대한 평가가 필요할 것으로 사료된다. 아울러 의학시뮬레이션의 다양한 교육방법에 대하여 소개를 하고자 하였다.