• Title/Summary/Keyword: measurement Noise

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Optimization of Subtraction Brain Perfusion SPECT with Basal/Acetazolamide Consecutive Acquisition (기저/아세타졸아미드 부하 연속 촬영 뇌관류 SPECT 최적화)

  • Lee, Dong-Soo;Lee, Tae-Hoon;Kim, Kyeong-Min;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.3
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    • pp.330-338
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    • 1997
  • This study investigated the method to adjust acquisition time(a) and injection dose (i) to make the best basal and subtraction images in consecutive SPECT. Image quality was assumed to be mainly affected by signal to noise ratio(S/N). Basal image was subtracted from the second image consecutively acquired at the same position. We calculated S/N ratio in basal SPECT images($S_1/N_1$) and subtraction SPECT images(Ss/Ns) to find a(time) and i(dose) to maximize S/N of both images at the same time. From phantom images, we drew the relation of image counts and a(time) and i(dose) in our system using fanbeam-high-resolution collimated triple head SPECT. Noise by imaging process depended on Poisson distribution. We took maximum tolerable duration of consecutive acquisition as 30 minutes and maximum injectible dose as 1,850MBq(50 mCi)(sum of two injections) per study. Counts of second-acquired image($S_2$), counts($S_s$) and noise($N_s$) of subtraction SPECT were as follows. $C_1$ was the coefficient of measurement with our system. $$S_2=S_1{\cdot}(\frac{30-a}{a})+background{\cdot}(1-\frac{30-a}{a})+C_1{\cdot}(30-a){\cdot}{\epsilon}{\cdot}(50-i)$$ $$Ss=S_2-\{S_1{\cdot}(\frac{30-a}{a})+background{\cdot}(1-\frac{(30-a)}{a})\}$$ $$Ns={\sqrt{N_2^2+N_1^2{\cdot}\frac{(30-a)^2}{a^2}}={\sqrt{S_2+S_1{\cdot}\frac{(30-a)^2}{a^2}}$$ In case of rest/acetazolamide study, effect(${\epsilon}$) of acetazolamide to increase global brain uptake of Tc-99m-HMPAO could be 1.5 or less. Varying ${\epsilon}$ from 1 to 1.5, a(time) and i(dose) pair to maximize both $S_1/N_l$ and Ss/Ns was determined. 15 mCi/17 min and 35mCi/13min was the best a(time) and i(dose) pair for rest/acetazolamide study(when ${\epsilon}$ were 1.2) and came to be used for our clinical routine after this study. We developed simple method to maximize S/N ratios of basal and subtraction SPECT from consecutive acquisition. This method could be applied to ECD/HMPAO and brain activation studies as well as rest/acetazolamide studies.

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Asymmetric Activation in the Prefrontal Cortex and Heart Rate Variability by Sound-induced Affects (음향감성에 의한 전전두엽의 비대칭성과 심박동변이도)

  • Jang Eun-Hye;Lee Ji-Hye;Lee Sang-Tae;Kim Wuon-Shik
    • Science of Emotion and Sensibility
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    • v.8 no.1
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    • pp.47-54
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    • 2005
  • This study is aimed to inspect how the different sensitivities in Behavioral activation system(BAS) and behavioral inhibition system(BIS) modulate on the properties of physiological responses stimulated by positive or negative affective sound. We measured the electroencephalogram(EEG) and electrocardiogram (ECG) of 32 students, consisted of four groups depending on the BAS and BIS sensitivities, during listening to meditation music or noise. The EEG was recorded at Fpl and Fp2 sites and Power spectral density(PSD) of HRV was derived from the ECG, and the power of HRV was calculated for 3 major frequency ranges(low frequency[LF], medium frequency and high frequency[HF]). After listening to music or noise, subjects reported the affect induced by the sound. For EEG, the power in the alpha band at Fp2, especially in the alpha-2 band(9.0-11.0 Hz) increased during the subjects listening to music, while the power at Fpl increased during noise. During listening to meditation music, there is a tendency that the left-sided activation in prefrontal cortex(PFC) is positively correlated with the difference of BAS(Z)-BIS(Z). During listening to noise, there is a tendency that the right-sided activation in PFC is dominant in case any of the sensitivity of BAS or BIS is high. For HRV, we found that the index of MF/(LF+HF), during listening to music, was higher significantly in the individuals with a low BIS but high BAS than in the individuals with a low sensitivity both BIS and BAS individuals. With high BIS, regardless of the BAS sensitivity, the difference of this index values was not significant. From these results we suggest that the physiological responses of different individuals in BAS and BIS react differently under the same emotionally provocative challenge.

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Wideband CMOS Voltage-Controlled Oscillator(VCO) for Multi-mode Vehicular Terminal (융복합 차량 수신기를 위한 광대역 전압제어 발진기)

  • Choi, Hyun-Seok;Diep, Bui Quag;Kang, So-Young;Jang, Joo-Young;Bang, Jai-Hoon;Oh, Inn-Yul;Park, Chul-Soon
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.7 no.6
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    • pp.63-69
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    • 2008
  • Reconfigurable RF one-chip solutions have been researched with the objective of designing for smaller-sized and more economical RF transceiver and it can be applied to a vehicular wireless terminal. The proposed voltage-controlled oscillator satisfies the targeted frequency range ($4.2{\sim}5.4\;GHz$) and the frequency planning which correspond to the standards such as CDMA(IS-95), PCS, GSM850, EGSM, WCDMA, WLAN, Bluetooth, WiBro, S-DMB, DSRC, GPS, and DVB-H/DMB-H/L(L Band). In order to improve phase noise performance, PMOS is adopted in the cross-coupled pair, the tail current source and MOS varactor in this VCO and differential-typed switching is proposed in capacitor array. Based on the measurement results, a total power dissipation is $5.3{\sim}6.0\;mW$ at 1.8 V power supply voltage. The oscillator is tuned from 4.05 to 5.62 GHz; The tuning range is 33%. The phase noise is -117.16 dBc/Hz at 1 MHz offset frequency and the FOM (Figure Of Merit) is $-180.84{\sim}-180.5$.

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Development of V-band Wireless Transceiver using MMIC Modules (MMIC 모듈을 이용한 V-band 무선 송수신 시스템의 구축)

  • Lee, Sang-Jin;An, Dan;Lee, Mun-Kyo;Go, Du-Hyun;Jin, Jin-Man;Kim, Sung-Chan;Kim, Sam-Dong;Park, Hyun-Chang;Park, Hyung-Moo;Rhee, Jin-Koo
    • Proceedings of the IEEK Conference
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    • 2005.11a
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    • pp.575-578
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    • 2005
  • We report on a low-cost V-band wireless transceiver with no use of any local oscillator in the receiver block using a self-heterodyne architecture. V-band Microwave monolithic IC (MMIC) modules were developed to demonstrate the wireless transceiver using coplanar waveguide (CPW) and GaAs PHEMT technologies. The MMIC modules such as the MMIC low noise amplifier (LNA), medium power amplifier (MPA) and the up/down-mixer were installed in the transceiver system. To interface the MMIC chips with the component modules for the transceiver system, CPW-to-waveguide fin-line transition modules of WR-15 type were designed and fabricated. The fabricated LNA modules showed a $S_{21}$ gain of 8.4 dB and a noise figure of 5.6 dB at 58 GHz. The MPA modules exhibited a gain of 6.9 dB and a $P_1$ $_{dB}$ of 5.4 dBm at 58 GHz. The conversion losses of the up-mixer and the down-mixer module were 14.3 dB at a LO power of 15 dBm, and 19.7 dB at a LO power of 0 dBm, respectively. From the measurement of V-band wireless transceiver, a conversion gain of 0.2 dB and a P $_{1dB}$ of 5.2 dBm were obtained in the transmitter block. The receiver block showed a conversion gain of 2.1 dB and a P $_{1dB}$ of -18.6 dBm. The wireless transceiver system demonstrated a successful data transfer within a distance of 5 meters.

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Performance evaluation using BER/SNR of wearable fabric reconfigurable beam-steering antenna for On/Off-body communication systems (On/Off-body 통신시스템을 위한 직물소재 웨어러블 재구성 빔 스티어링 안테나의 BER/SNR 성능 검증)

  • Kang, Seonghun;Jeong, Sangsoo;Jung, Chang Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.7
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    • pp.4842-4848
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    • 2015
  • This paper presents a comparison of communication performance between the reconfigurable beam-steering antenna and the omni-directional (loop) antenna during standstill and walking motion. Both omni-directional and reconfigurable antennas were manufactured on the same fabric (${\varepsilon}_r=1.35$, $tqn{\delta}=0.02$) substrate and operated around 5 GHz band. The reconfigurable antenna was designed to steer the beam directions. To implement the beam-steering capability, the antenna used two PIN diodes. The measured peak gains were 5.9-6.6 dBi and the overall half power beam width (HPBW) was $102^{\circ}$. In order to compare the communication efficiency, both the bit error rate (BER) and the signal-to-noise ratio (SNR) were measured using a GNU Radio Companion software tool and user software radio peripheral (USRP) devices. The measurement were performed when both antennas were standstill and walking motion in an antenna chamber as well as in a smart home environment. From these results, the performances of the reconfigurable beam steering antenna outperformed that of the loop antenna. In addition, in terms of communication efficiencies, in an antenna chamber was better than in a smart home environment. In terms of movement of antennas, standstill state has better results than walking motion state.

Investigation Into Reflectance Characteristics of Trees Infected by Pine Wilt Disease (소나무재선충병 감염목의 분광반사 특성 구명)

  • Kim, So-Ra;Lee, Woo-Kyun;Nam, Kijun;Song, Yongho;Yu, Hangnan;Kim, Moon-Il;Lee, Jong-Yeol;Lee, Seung-Ho
    • Journal of Korean Society of Forest Science
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    • v.102 no.4
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    • pp.499-505
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    • 2013
  • Pine wilt disease has known as a serious forest disease in East Asia such as Japan, Korea and China. Fumigation and burning are considered as best way to treat infected tree at early detection. For investigate spectral reflectance characteristics of infected trees, periodic measurement has been done in both infected and non-infected trees. Infected and non-infected trees' reflectance (400 nm~2,500 nm wavelength) are detected from June to October with GER3700 spectrometer. Noise of reflectance data was corrected using cubic spline interpolation method. Reflectance was changed in most of infected trees with ranges Red (600 nm~700 nm) and Middle Infrared (1,400 nm~1,500 nm) within two months after injected by Pine Wood nematode (PWN), but there was no differences in non-infected trees. Infected and non-infected trees were compared statistically in each period. As a result, we found that a statistically significant difference was occurred at Red and Middle Infrared (MIR) 2 months after injection (p<0.05), however, no significant difference in near infrared (p>0.05). Therefore, the early detection of infested pine trees by PWN may possible through detecting the change of spectral reflectance at red and MIR.

Comparison of Three, Motion-Resistant MR Sequences on Hepatobiliary Phase for Gadoxetic Acid (Gd-EOB-DTPA)-Enhanced MR Imaging of the Liver

  • Kim, Doo Ri;Kim, Bong Soo;Lee, Jeong Sub;Choi, Guk Myung;Kim, Seung Hyoung;Goh, Myeng Ju;Song, Byung-Cheol;Lee, Mu Sook;Lee, Kyung Ryeol;Ko, Su Yeon
    • Investigative Magnetic Resonance Imaging
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    • v.21 no.2
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    • pp.71-81
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    • 2017
  • Purpose: To compare three, motion-resistant, T1-weighted MR sequences on the hepatobiliary phase for gadoxetic acid-enhanced MR imaging of the liver. Materials and Methods: In this retrospective study, 79 patients underwent gadoxetic acid-enhanced, 3T liver MR imaging. Fifty-nine were examined using a standard protocol, and 20 were examined using a motion-resistant protocol. During the hepatocyte-specific phase, three MR sequences were acquired: 1) gradient recalled echo (GRE) with controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA); 2) radial GRE with the interleaved angle-bisection scheme (ILAB); and 3) radial GRE with golden-angle scheme (GA). Two readers independently assessed images with motion artifacts, streaking artifacts, liver-edge sharpness, hepatic vessel clarity, lesion conspicuity, and overall image quality, using a 5-point scale. The images were assessed by measurement of liver signal-to-noise ratio (SNR), and tumor-to-liver contrast-to-noise ratio (CNR). The results were compared, using repeated post-hoc, paired t-tests with Bonferroni correction and the Wilcoxon signed rank test with Bonferroni correction. Results: In the qualitative analysis of cooperative patients, the results for CAIPIRINHA had significantly higher ratings for streak artifacts, liver-edge sharpness, hepatic vessel clarity, and overall image quality as compared to, radial GRE, (P < 0.016). In the imaging of uncooperative patients, higher scores were recorded for ILAB and GA with respect to all of the qualitative assessments, except for streak artifact, compared with CAIPIRINHA (P < 0.016). However, no significant differences were found between ILAB and GA. For quantitative analysis in uncooperative patients, the mean liver SNR and lesion-to-liver CNR with radial GRE were significantly higher than those of CAIPIRINHA (P < 0.016). Conclusion: In uncooperative patients, the use of the radial GRE sequence can improve the image quality compared to GRE imaging with CAIPIRINHA, despite the data acquisition methods used. The GRE imaging with CAIPIRINHA is applicable for patients without breath-holding difficulties.

Photochemical/Biophysical Properties of Proteorhodopsin and Anabaena Sensory Rhodopsin in Various Physical Environments (막 단백질인 Proteorhodopsin과 Anabaena Sensory Rhodopsin의 다양한 측정 환경에 따른 광화학/생물리학적 특성)

  • Choi, Ah-Reum;Han, Song-I;Chung, Young-Ho;Jung, Kwang-Hwan
    • Korean Journal of Microbiology
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    • v.47 no.1
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    • pp.22-29
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    • 2011
  • Rhodopsin is a membrane protein with seven transmembrane region which contains a retinal as its chromophore. Although there have been recently reports on various photo-biochemical features of rhodopsins by a wide range of purifying and measurement methods, there was no actual comparison related to the difference of biochemical characteristics according to their physical environment of rhodopsins. First, proteorhodopsin (PR) was found in marine proteobacteria whose function is known for pumping proton using light energy. Second one is Anabaena sensory rhodopsin (Nostoc sp.) PCC7120 (ASR) which belongs to eubacteria acts as sensory regulator since it is co-expressed with transducer 14 kDa in an operon. In this study, we applied two types of rhodopsins (PR and ASR) to various environmental conditions such as in Escherichia coli membranes, membrane in acrylamide gel, in DDM (n-dodecyl-${\beta}$-D-maltopyranoside), OG (octyl-${\beta}$-D-glucopyranoside), and reconstituted with DOPC (1,2-didecanoyl-sn-glycero-3-phosphocholine). According to the light-induced difference spectroscopy, rhodopsins in 0.02% DDM clearly showed photointermediates like M, and O states which respond to the different wavelengths, respectively and showed the best signal/noise ratio. The laser-induced difference spectra showed the fast formation and decay rate of photointermediates in the DDM solubilized samples than gel encapsulated rhodopsin. Each of rhodopsins seemed to be adapted to its surrounding environment.

Transient Torsional Vibration Analysis of Ice-class Propulsion Shafting System Driven by Electric Motor (전기 모터 구동 대빙급 추진 시스템의 과도 비틀림 진동 분석)

  • Barro, Ronald D.;Lee, Don Chool
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.24 no.9
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    • pp.667-674
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    • 2014
  • A ship's propulsion shafting system is subjected to varying magnitudes of intermittent loadings that pose great risks such as failure. Consequently, the dynamic characteristic of a propulsion shafting system must be designed to withstand the resonance that occurs during operation. This resonance results from hydrodynamic interaction between the propeller and fluid. For ice-class vessels, this interaction takes place between the propeller and ice. Producing load- and resonance-induced stresses, the propeller-ice interaction is the primary source of excitation, making it a major focus in the design requirements of propulsion shafting systems. This paper examines the transient torsional vibration response of the propulsion shafting system of an ice-class research vessel. The propulsion train is composed of an electric motor, flexible coupling, spherical gears, and a propeller configuration. In this paper, the theoretical analysis of transient torsional vibration and propeller-ice interaction loading is first discussed, followed by an explanation of the actual transient torsional vibration measurements. Measurement data for the analysis were compared with an applied estimation factor for the propulsion shafting design torque limit, and they were evaluated using an existing international standard. Addressing the transient torsional vibration of a propulsion shafting system with an electric motor, this paper also illustrates the influence of flexible coupling stiffness design on resulting resonance. Lastly, the paper concludes with a proposal to further study the existence of negative torque on a gear train and its overall effect on propulsion shafting systems.

The study of X-ray detection characteristic and fabrication photoconductor film thickness for Screen printing method (Screen printing method로 제작된 의료용 광도전체 필름의 Tickness의 따른 X선 검출 특성 평가)

  • Lee, Y.K.;Yon, M.S.;KIM, D.H.;Chun, S.L.;Jung, B.D.;Gang, Sang-Sik;Park, J.G.;Mun, C.W.;Nam, S.H.
    • Journal of the Korean Society of Radiology
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    • v.3 no.2
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    • pp.11-16
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    • 2009
  • Mercury Iodide as good sensitivity at radiation and has an easy peculiarity that operates at low voltage for other photoconductors(a-Se, a-Si, Ge, etc) Based on this characteristic, we studied about an efficiency of the digital x-ray detector in acccordance with the thickness of photoconductor. To solve the problem that is difficult to make a large area film using PVD(Physical Vapor Deposition)method, we used a PIB(Particle In Binder)method. To make a binder paste, we used a PVB(Polyvinylbutyral) as a binder and a DGME(Diethylene Glycol Monobutyl Ether), DGMEA(Diethylene Glycol Monobutyl Ether Acetate) as a solvent. Using this binder paste, we made a polycrystal mercury iodide film that has an each thickness. To evaluate the electrical properties of this films, we measured a darkcurrent, sensitivity and SNR(Signal to Noise Ratio). Mercury iodide film of the 200um thickness has good electrical properties as a result of the measurement. From this result there is a good chance that replace the existing a-Se(Amnorphous seleinum; a-se) with the mercury iodide.

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